Characterization and application of fungal metabolites and assessment of new biofungicides potential

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Characterization and application of fungal metabolites and assessment of new biofungicides potential (en)
Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (sr)
Karakterizacija i primena metabolita gljiva i utvrđivanje potencijala novih biofungicida (sr_RS)
Authors

Publications

Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa

Stanković, Jovana; Gođevac, Dejan; Tešević, Vele; Dajić-Stevanović, Zora; Ćirić, Ana D.; Soković, Marina; Novaković, Miroslav M.

(American Chemical Society, 2019)

TY  - JOUR
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3725
AB  - A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa
VL  - 82
IS  - 6
SP  - 1487
EP  - 1495
DO  - 10.1021/acs.jnatprod.8b00970
ER  - 
@article{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
abstract = "A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa",
volume = "82",
number = "6",
pages = "1487-1495",
doi = "10.1021/acs.jnatprod.8b00970"
}
Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products
American Chemical Society., 82(6), 1487-1495.
https://doi.org/10.1021/acs.jnatprod.8b00970
Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products. 2019;82(6):1487-1495.
doi:10.1021/acs.jnatprod.8b00970 .
Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa" in Journal of Natural Products, 82, no. 6 (2019):1487-1495,
https://doi.org/10.1021/acs.jnatprod.8b00970 . .
4
5
5
4

Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970

Stanković, Jovana; Gođevac, Dejan; Tešević, Vele; Dajić-Stevanović, Zora; Ćirić, Ana D.; Soković, Marina; Novaković, Miroslav M.

(American Chemical Society, 2019)

TY  - DATA
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3726
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970
ER  - 
@misc{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970"
}
Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products
American Chemical Society..
Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products. 2019;..
Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970" in Journal of Natural Products (2019).

Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003

Ljaljević-Grbić, Milica; Unković, Nikola; Dimkić, Ivica; Janaćković, Peđa T.; Gavrilović, Milan; Stanojević, Olja; Stupar, Miloš; Vujisić, Ljubodrag V.; Jelikić, Aleksa; Stanković, Slaviša; Vukojević, Jelena

(Elsevier Ireland Ltd, Clare, 2018)

TY  - DATA
AU  - Ljaljević-Grbić, Milica
AU  - Unković, Nikola
AU  - Dimkić, Ivica
AU  - Janaćković, Peđa T.
AU  - Gavrilović, Milan
AU  - Stanojević, Olja
AU  - Stupar, Miloš
AU  - Vujisić, Ljubodrag V.
AU  - Jelikić, Aleksa
AU  - Stanković, Slaviša
AU  - Vukojević, Jelena
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2931
PB  - Elsevier Ireland Ltd, Clare
T2  - Journal of Ethnopharmacology
T1  - Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003
ER  - 
@misc{
author = "Ljaljević-Grbić, Milica and Unković, Nikola and Dimkić, Ivica and Janaćković, Peđa T. and Gavrilović, Milan and Stanojević, Olja and Stupar, Miloš and Vujisić, Ljubodrag V. and Jelikić, Aleksa and Stanković, Slaviša and Vukojević, Jelena",
year = "2018",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Journal of Ethnopharmacology",
title = "Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003"
}
Ljaljević-Grbić, M., Unković, N., Dimkić, I., Janaćković, P. T., Gavrilović, M., Stanojević, O., Stupar, M., Vujisić, L. V., Jelikić, A., Stanković, S.,& Vukojević, J.. (2018). Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003. in Journal of Ethnopharmacology
Elsevier Ireland Ltd, Clare..
Ljaljević-Grbić M, Unković N, Dimkić I, Janaćković PT, Gavrilović M, Stanojević O, Stupar M, Vujisić LV, Jelikić A, Stanković S, Vukojević J. Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003. in Journal of Ethnopharmacology. 2018;..
Ljaljević-Grbić, Milica, Unković, Nikola, Dimkić, Ivica, Janaćković, Peđa T., Gavrilović, Milan, Stanojević, Olja, Stupar, Miloš, Vujisić, Ljubodrag V., Jelikić, Aleksa, Stanković, Slaviša, Vukojević, Jelena, "Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003" in Journal of Ethnopharmacology (2018).

Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526

Ilic, Bojan; Dimkić, Ivica; Unković, Nikola; Ljaljević-Grbić, Milica; Vukojević, Jelena; Vujisić, Ljubodrag V.; Tešević, Vele; Stanković, Slaviša; Makarov, Slobodan E.; Lučić, Luka

(Wiley, Hoboken, 2018)

TY  - DATA
AU  - Ilic, Bojan
AU  - Dimkić, Ivica
AU  - Unković, Nikola
AU  - Ljaljević-Grbić, Milica
AU  - Vukojević, Jelena
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Stanković, Slaviša
AU  - Makarov, Slobodan E.
AU  - Lučić, Luka
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3238
PB  - Wiley, Hoboken
T2  - Journal of Applied Entomology
T1  - Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526
ER  - 
@misc{
author = "Ilic, Bojan and Dimkić, Ivica and Unković, Nikola and Ljaljević-Grbić, Milica and Vukojević, Jelena and Vujisić, Ljubodrag V. and Tešević, Vele and Stanković, Slaviša and Makarov, Slobodan E. and Lučić, Luka",
year = "2018",
publisher = "Wiley, Hoboken",
journal = "Journal of Applied Entomology",
title = "Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526"
}
Ilic, B., Dimkić, I., Unković, N., Ljaljević-Grbić, M., Vukojević, J., Vujisić, L. V., Tešević, V., Stanković, S., Makarov, S. E.,& Lučić, L.. (2018). Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526. in Journal of Applied Entomology
Wiley, Hoboken..
Ilic B, Dimkić I, Unković N, Ljaljević-Grbić M, Vukojević J, Vujisić LV, Tešević V, Stanković S, Makarov SE, Lučić L. Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526. in Journal of Applied Entomology. 2018;..
Ilic, Bojan, Dimkić, Ivica, Unković, Nikola, Ljaljević-Grbić, Milica, Vukojević, Jelena, Vujisić, Ljubodrag V., Tešević, Vele, Stanković, Slaviša, Makarov, Slobodan E., Lučić, Luka, "Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526" in Journal of Applied Entomology (2018).

Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?

Ljaljević-Grbić, Milica; Unković, Nikola; Dimkić, Ivica; Janaćković, Peđa T.; Gavrilović, Milan; Stanojević, Olja; Stupar, Miloš; Vujisić, Ljubodrag V.; Jelikić, Aleksa; Stanković, Slaviša; Vukojević, Jelena

(Elsevier Ireland Ltd, Clare, 2018)

TY  - JOUR
AU  - Ljaljević-Grbić, Milica
AU  - Unković, Nikola
AU  - Dimkić, Ivica
AU  - Janaćković, Peđa T.
AU  - Gavrilović, Milan
AU  - Stanojević, Olja
AU  - Stupar, Miloš
AU  - Vujisić, Ljubodrag V.
AU  - Jelikić, Aleksa
AU  - Stanković, Slaviša
AU  - Vukojević, Jelena
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2158
AB  - Ethnopharmacological relevance: Essential oils obtained from resins of Boswellia carteri Birdw. and Commiphora myrrha (Nees) Engl., commonly known as frankincense and true myrrh respectively, have been used extensively since 2800 BCE for the treatment of skin sores, wounds, teeth, inflammation, and urinary tract diseases in traditional medicine; for preparation of mummification balms and unguents; and also as incense and perfumes. Since ancient times, burning of frankincense and myrrh in places of worship for spiritual purposes and contemplation (a ubiquitous practice across various religions) had hygienic functions, to refine the smell and reduce contagion by purifying the indoor air. Aim of the study: The general purpose of the study was to assess the in vitro antimicrobial potential of the liquid and vapour phases of B. carteri and C. myrrha essential oils and burn incense, as well as to test the effectiveness of their in situ application to cleanse microbially-contaminated air within the ambient of an investigated 17th century church. Materials and methods: The chemical composition of B. carteri and C. myrrha essential oils, obtained by hydro distillation of frankincense and true myrrh oleo gum resins was determined using GC/MS, and antimicrobial properties of their liquid and vapour phases were assessed by the broth microdilution and microatmosphere diffusion methods. Chemical analysis of burn incense fume obtained using bottle gas washing with dichloromethane as a solvent was performed by GC/MS, while its antimicrobial activity was evaluated using a modified microatmosphere diffusion method to evaluate germination inhibition for fungi and CFU count reduction for bacteria. The in situ antimicrobial activity of B. carteri burn incense and essential oil vapour phase was assessed in the sealed nave and diaconicon of the church, respectively. Results: The dominant compounds of B. carteri EO were a-pinene (38.41%) and myrcene (15.21%), while C. myrrha EO was characterized by high content of furanoeudesma-1,3-diene (17.65%), followed by curzerene (12.97%), f3-elemene (12.70%), and germacrene B (12.15%). Burn incense fume and soot had a-pinene (68.6%) and incensole (28.6%) as the most dominant compounds, respectively. In vitro antimicrobial assays demonstrated high bacterial and fungal sensitivity to the liquid and vapour phases of Eos, and burn incense fume. In situ application of B. carteri EO vapour and incense fume resulted in reduction of air -borne viable microbial counts by up to 45.39 +/- 2.83% for fungi and 67.56 +/- 3.12% for bacteria (EO); and by up to 80.43 +/- 2.07% for fungi and 91.43 +/- 1.26% for bacteria (incense fume). Conclusions: The antimicrobial properties of essential oil derived from frankincense, a compound with wellknown traditional use, showed that it possesses a clear potential as a natural antimicrobial agent. Moreover, the results suggest possible application of B. carteri EO vapour and incense fume as occasional air purifiers in sacral ambients, apart from daily church rituals.
PB  - Elsevier Ireland Ltd, Clare
T2  - Journal of Ethnopharmacology
T1  - Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?
VL  - 219
SP  - 1
EP  - 14
DO  - 10.1016/j.jep.2018.03.003
UR  - Kon_3489
ER  - 
@article{
author = "Ljaljević-Grbić, Milica and Unković, Nikola and Dimkić, Ivica and Janaćković, Peđa T. and Gavrilović, Milan and Stanojević, Olja and Stupar, Miloš and Vujisić, Ljubodrag V. and Jelikić, Aleksa and Stanković, Slaviša and Vukojević, Jelena",
year = "2018",
abstract = "Ethnopharmacological relevance: Essential oils obtained from resins of Boswellia carteri Birdw. and Commiphora myrrha (Nees) Engl., commonly known as frankincense and true myrrh respectively, have been used extensively since 2800 BCE for the treatment of skin sores, wounds, teeth, inflammation, and urinary tract diseases in traditional medicine; for preparation of mummification balms and unguents; and also as incense and perfumes. Since ancient times, burning of frankincense and myrrh in places of worship for spiritual purposes and contemplation (a ubiquitous practice across various religions) had hygienic functions, to refine the smell and reduce contagion by purifying the indoor air. Aim of the study: The general purpose of the study was to assess the in vitro antimicrobial potential of the liquid and vapour phases of B. carteri and C. myrrha essential oils and burn incense, as well as to test the effectiveness of their in situ application to cleanse microbially-contaminated air within the ambient of an investigated 17th century church. Materials and methods: The chemical composition of B. carteri and C. myrrha essential oils, obtained by hydro distillation of frankincense and true myrrh oleo gum resins was determined using GC/MS, and antimicrobial properties of their liquid and vapour phases were assessed by the broth microdilution and microatmosphere diffusion methods. Chemical analysis of burn incense fume obtained using bottle gas washing with dichloromethane as a solvent was performed by GC/MS, while its antimicrobial activity was evaluated using a modified microatmosphere diffusion method to evaluate germination inhibition for fungi and CFU count reduction for bacteria. The in situ antimicrobial activity of B. carteri burn incense and essential oil vapour phase was assessed in the sealed nave and diaconicon of the church, respectively. Results: The dominant compounds of B. carteri EO were a-pinene (38.41%) and myrcene (15.21%), while C. myrrha EO was characterized by high content of furanoeudesma-1,3-diene (17.65%), followed by curzerene (12.97%), f3-elemene (12.70%), and germacrene B (12.15%). Burn incense fume and soot had a-pinene (68.6%) and incensole (28.6%) as the most dominant compounds, respectively. In vitro antimicrobial assays demonstrated high bacterial and fungal sensitivity to the liquid and vapour phases of Eos, and burn incense fume. In situ application of B. carteri EO vapour and incense fume resulted in reduction of air -borne viable microbial counts by up to 45.39 +/- 2.83% for fungi and 67.56 +/- 3.12% for bacteria (EO); and by up to 80.43 +/- 2.07% for fungi and 91.43 +/- 1.26% for bacteria (incense fume). Conclusions: The antimicrobial properties of essential oil derived from frankincense, a compound with wellknown traditional use, showed that it possesses a clear potential as a natural antimicrobial agent. Moreover, the results suggest possible application of B. carteri EO vapour and incense fume as occasional air purifiers in sacral ambients, apart from daily church rituals.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Journal of Ethnopharmacology",
title = "Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?",
volume = "219",
pages = "1-14",
doi = "10.1016/j.jep.2018.03.003",
url = "Kon_3489"
}
Ljaljević-Grbić, M., Unković, N., Dimkić, I., Janaćković, P. T., Gavrilović, M., Stanojević, O., Stupar, M., Vujisić, L. V., Jelikić, A., Stanković, S.,& Vukojević, J.. (2018). Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?. in Journal of Ethnopharmacology
Elsevier Ireland Ltd, Clare., 219, 1-14.
https://doi.org/10.1016/j.jep.2018.03.003
Kon_3489
Ljaljević-Grbić M, Unković N, Dimkić I, Janaćković PT, Gavrilović M, Stanojević O, Stupar M, Vujisić LV, Jelikić A, Stanković S, Vukojević J. Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?. in Journal of Ethnopharmacology. 2018;219:1-14.
doi:10.1016/j.jep.2018.03.003
Kon_3489 .
Ljaljević-Grbić, Milica, Unković, Nikola, Dimkić, Ivica, Janaćković, Peđa T., Gavrilović, Milan, Stanojević, Olja, Stupar, Miloš, Vujisić, Ljubodrag V., Jelikić, Aleksa, Stanković, Slaviša, Vukojević, Jelena, "Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?" in Journal of Ethnopharmacology, 219 (2018):1-14,
https://doi.org/10.1016/j.jep.2018.03.003 .,
Kon_3489 .
25
14
12
13

Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents

Ilic, Bojan; Dimkić, Ivica; Unković, Nikola; Ljaljević-Grbić, Milica; Vukojević, Jelena; Vujisić, Ljubodrag V.; Tešević, Vele; Stanković, Slaviša; Makarov, Slobodan E.; Lučić, Luka

(Wiley, Hoboken, 2018)

TY  - JOUR
AU  - Ilic, Bojan
AU  - Dimkić, Ivica
AU  - Unković, Nikola
AU  - Ljaljević-Grbić, Milica
AU  - Vukojević, Jelena
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Stanković, Slaviša
AU  - Makarov, Slobodan E.
AU  - Lučić, Luka
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2198
AB  - In the light of growing interest in discovering new sources of natural antimicrobial agents, we extracted and tested the efficiency of julid defensive secretions in comparison with commercially used antibiotic and antimycotics. This work involved chemical characterization of the defensive secretions of Cylindroiulus boleti (C. L. Koch, 1847), Megaphyllum bosniense (Verhoeff, 1897) and M.unilineatum (C. L. Koch, 1838), as well as in vitro evaluation of their antimicrobial activity against 11 bacteria, one yeast and eight filamentous fungi. Compounds of the analysed defensive secretions included p-benzoquinones, alkyl esters of fatty acids and ketones. Ketones were recorded for the first time in the order Julida, and they were detected in secretions of both Megaphyllum species. All three analysed defensive secretions showed antibacterial and antifungal potential against all of the tested pathogens. Staphylococcus aureus proved to be the most sensitive bacterial strain to all analysed secretions. Also, defensive secretion of M.unilineatum showed significant antibacterial potential against Bacillus subtilis. The most resistant bacterial strains in this study were Escherichia coli, Erwinia persicina and Pseudomonas syringae pv. tomato. Analysed defensive secretions achieved the strongest antifungal activity against Aspergillus parasiticus (secretions of all three millipede species), Penicillium griseofulvum (secretions of C.boleti and M.bosniense) and Cladosporium oxysporum (secretion of M.unilineatum). The most resistant mycromycetes were A.niger (to all tested defensive secretions), A.flavus (to secretion of M.unilineatum) and P.lanosum (to secretions of C.boleti and M.bosniense). Our results showed a generally lower level of activity compared to antibiotic and a significantly higher level compared to antimycotics. The results of this study elucidate and open opportunities for further research in the field of millipede chemical ecology.
PB  - Wiley, Hoboken
T2  - Journal of Applied Entomology
T1  - Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents
VL  - 142
IS  - 8
SP  - 775
EP  - 791
DO  - 10.1111/jen.12526
UR  - Kon_3529
ER  - 
@article{
author = "Ilic, Bojan and Dimkić, Ivica and Unković, Nikola and Ljaljević-Grbić, Milica and Vukojević, Jelena and Vujisić, Ljubodrag V. and Tešević, Vele and Stanković, Slaviša and Makarov, Slobodan E. and Lučić, Luka",
year = "2018",
abstract = "In the light of growing interest in discovering new sources of natural antimicrobial agents, we extracted and tested the efficiency of julid defensive secretions in comparison with commercially used antibiotic and antimycotics. This work involved chemical characterization of the defensive secretions of Cylindroiulus boleti (C. L. Koch, 1847), Megaphyllum bosniense (Verhoeff, 1897) and M.unilineatum (C. L. Koch, 1838), as well as in vitro evaluation of their antimicrobial activity against 11 bacteria, one yeast and eight filamentous fungi. Compounds of the analysed defensive secretions included p-benzoquinones, alkyl esters of fatty acids and ketones. Ketones were recorded for the first time in the order Julida, and they were detected in secretions of both Megaphyllum species. All three analysed defensive secretions showed antibacterial and antifungal potential against all of the tested pathogens. Staphylococcus aureus proved to be the most sensitive bacterial strain to all analysed secretions. Also, defensive secretion of M.unilineatum showed significant antibacterial potential against Bacillus subtilis. The most resistant bacterial strains in this study were Escherichia coli, Erwinia persicina and Pseudomonas syringae pv. tomato. Analysed defensive secretions achieved the strongest antifungal activity against Aspergillus parasiticus (secretions of all three millipede species), Penicillium griseofulvum (secretions of C.boleti and M.bosniense) and Cladosporium oxysporum (secretion of M.unilineatum). The most resistant mycromycetes were A.niger (to all tested defensive secretions), A.flavus (to secretion of M.unilineatum) and P.lanosum (to secretions of C.boleti and M.bosniense). Our results showed a generally lower level of activity compared to antibiotic and a significantly higher level compared to antimycotics. The results of this study elucidate and open opportunities for further research in the field of millipede chemical ecology.",
publisher = "Wiley, Hoboken",
journal = "Journal of Applied Entomology",
title = "Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents",
volume = "142",
number = "8",
pages = "775-791",
doi = "10.1111/jen.12526",
url = "Kon_3529"
}
Ilic, B., Dimkić, I., Unković, N., Ljaljević-Grbić, M., Vukojević, J., Vujisić, L. V., Tešević, V., Stanković, S., Makarov, S. E.,& Lučić, L.. (2018). Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents. in Journal of Applied Entomology
Wiley, Hoboken., 142(8), 775-791.
https://doi.org/10.1111/jen.12526
Kon_3529
Ilic B, Dimkić I, Unković N, Ljaljević-Grbić M, Vukojević J, Vujisić LV, Tešević V, Stanković S, Makarov SE, Lučić L. Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents. in Journal of Applied Entomology. 2018;142(8):775-791.
doi:10.1111/jen.12526
Kon_3529 .
Ilic, Bojan, Dimkić, Ivica, Unković, Nikola, Ljaljević-Grbić, Milica, Vukojević, Jelena, Vujisić, Ljubodrag V., Tešević, Vele, Stanković, Slaviša, Makarov, Slobodan E., Lučić, Luka, "Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents" in Journal of Applied Entomology, 142, no. 8 (2018):775-791,
https://doi.org/10.1111/jen.12526 .,
Kon_3529 .
4
4
4

In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity

Božunović, Jelena; Živković, Suzana; Gašić, Uroš M.; Glamočlija, Jasmina; Ćirić, Ana D.; Matekalo, Dragana; Šiler, Branislav; Soković, Marina; Tešić, Živoslav Lj.; Mišić, Danijela

(Elsevier Science Bv, Amsterdam, 2018)

TY  - JOUR
AU  - Božunović, Jelena
AU  - Živković, Suzana
AU  - Gašić, Uroš M.
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Matekalo, Dragana
AU  - Šiler, Branislav
AU  - Soković, Marina
AU  - Tešić, Živoslav Lj.
AU  - Mišić, Danijela
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2579
AB  - The present study was principally aimed at ascertaining the differences in metabolomics profiles and biological activities between non-hydrolyzed (ME) and hydrolyzed methanol extract (HME) of Centaurium erythraea Rafn. UHPLC-MS/MS Orbitrap analysis showed that the enzymatic hydrolysis of the extract caused changes in beta-Dglycoside/aglycone ratio of both flavonoid and secoiridoid compounds. UHPLC/DAD/ + HESI - qqqMS characterization and/or quantification of secoiridoid glucosides (SGs) and their aglycones in both ME and HME revealed gentiopicral and erythrocentaurin as the major aglycones, the same metabolic products which appear after the hydrolysis of pure swertiamarin, the dominant secoiridoid glucoside of C. erythraea. SGs played an antioxidant role only in ABTS assay, whilst the remarkable antioxidant potential of C. erythraea methanol extract is ascribed chiefly to phenolics detected in it. Interestingly, antioxidant activities of swertiamarin and sweroside recorded in ABTS assay increased after the compounds have been hydrolyzed, which highlighted their possible antioxidant role during ingestion. Strong antimicrobial activities of ME and HME against a vast array of pathogens, which exceed the effects of the reference antibiotics and antimycotics, largely depended on the amount of secoiridoids in either of the glycosylation forms. Extracts and pure secoiridoids were especially effective against most of the tested Penicillium species. On the other hand, P. funiculosum has evolved an efficient mechanism of detoxification of sub-lethal concentrations of secoiridoid glucosides, involving their biotransformation and complete digestion. The presented findings will contribute to clarify the fate and role of the SGs after C. erythraea ingestion within in vivo systems, and to further promote this remarkable plant as a food preservation additive with significant health benefits.
PB  - Elsevier Science Bv, Amsterdam
T2  - Industrial Crops and Products
T1  - In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity
VL  - 111
SP  - 705
EP  - 721
DO  - 10.1016/j.indcrop.2017.11.040
UR  - Kon_3395
ER  - 
@article{
author = "Božunović, Jelena and Živković, Suzana and Gašić, Uroš M. and Glamočlija, Jasmina and Ćirić, Ana D. and Matekalo, Dragana and Šiler, Branislav and Soković, Marina and Tešić, Živoslav Lj. and Mišić, Danijela",
year = "2018",
abstract = "The present study was principally aimed at ascertaining the differences in metabolomics profiles and biological activities between non-hydrolyzed (ME) and hydrolyzed methanol extract (HME) of Centaurium erythraea Rafn. UHPLC-MS/MS Orbitrap analysis showed that the enzymatic hydrolysis of the extract caused changes in beta-Dglycoside/aglycone ratio of both flavonoid and secoiridoid compounds. UHPLC/DAD/ + HESI - qqqMS characterization and/or quantification of secoiridoid glucosides (SGs) and their aglycones in both ME and HME revealed gentiopicral and erythrocentaurin as the major aglycones, the same metabolic products which appear after the hydrolysis of pure swertiamarin, the dominant secoiridoid glucoside of C. erythraea. SGs played an antioxidant role only in ABTS assay, whilst the remarkable antioxidant potential of C. erythraea methanol extract is ascribed chiefly to phenolics detected in it. Interestingly, antioxidant activities of swertiamarin and sweroside recorded in ABTS assay increased after the compounds have been hydrolyzed, which highlighted their possible antioxidant role during ingestion. Strong antimicrobial activities of ME and HME against a vast array of pathogens, which exceed the effects of the reference antibiotics and antimycotics, largely depended on the amount of secoiridoids in either of the glycosylation forms. Extracts and pure secoiridoids were especially effective against most of the tested Penicillium species. On the other hand, P. funiculosum has evolved an efficient mechanism of detoxification of sub-lethal concentrations of secoiridoid glucosides, involving their biotransformation and complete digestion. The presented findings will contribute to clarify the fate and role of the SGs after C. erythraea ingestion within in vivo systems, and to further promote this remarkable plant as a food preservation additive with significant health benefits.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Industrial Crops and Products",
title = "In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity",
volume = "111",
pages = "705-721",
doi = "10.1016/j.indcrop.2017.11.040",
url = "Kon_3395"
}
Božunović, J., Živković, S., Gašić, U. M., Glamočlija, J., Ćirić, A. D., Matekalo, D., Šiler, B., Soković, M., Tešić, Ž. Lj.,& Mišić, D.. (2018). In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity. in Industrial Crops and Products
Elsevier Science Bv, Amsterdam., 111, 705-721.
https://doi.org/10.1016/j.indcrop.2017.11.040
Kon_3395
Božunović J, Živković S, Gašić UM, Glamočlija J, Ćirić AD, Matekalo D, Šiler B, Soković M, Tešić ŽL, Mišić D. In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity. in Industrial Crops and Products. 2018;111:705-721.
doi:10.1016/j.indcrop.2017.11.040
Kon_3395 .
Božunović, Jelena, Živković, Suzana, Gašić, Uroš M., Glamočlija, Jasmina, Ćirić, Ana D., Matekalo, Dragana, Šiler, Branislav, Soković, Marina, Tešić, Živoslav Lj., Mišić, Danijela, "In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity" in Industrial Crops and Products, 111 (2018):705-721,
https://doi.org/10.1016/j.indcrop.2017.11.040 .,
Kon_3395 .
1
16
13
16

Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative

Bukvicki, Danka; Giweli, Abdulhmid; Stojković, Dejan; Vujisić, Ljubodrag V.; Tešević, Vele; Nikolić, Miloš; Soković, Marina; Marin, Petar D.

(Elsevier Science Inc, New York, 2018)

TY  - JOUR
AU  - Bukvicki, Danka
AU  - Giweli, Abdulhmid
AU  - Stojković, Dejan
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Nikolić, Miloš
AU  - Soković, Marina
AU  - Marin, Petar D.
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2140
AB  - The essential oil of Thymus algeriensis was analyzed as a potential preservative in soft cheese. We developed a novel method to test the preserving properties of essential oil in soft cheese. Contamination incidence of Penicillium aurantiogriseum was absent after 30 d of storage at 4 degrees C with 25 mu L of essential oil added. The antimicrobial activity was tested against 8 bacteria and 8 fungi. Thymus algeriensis oil showed inhibitory activity against tested bacteria at 0.03 to 0.09 mg/mL, and bactericidal activity was achieved at 0.05 to 0.15 mg/mL. For antifungal activity, minimum inhibitory concentrations ranged between 0.01 and 0.04 mg/mL and minimum fungicidal concentrations between 0.01 and 0.04 mg/mL. Furthermore, the oil was also screened for antiradical activity using the 1,1-diphenyl-2-picrylhydrazyl assay. The results showed that the oil was active and achieved half-maximal inhibitory activity at 0.132 mg/mL. We used gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectrometry to investigate the volatile compounds from the oil. Carvacrol was identified as the main compound in the oil, represented by 80.9% of the total constituents, followed by p-cymene (7.7%).
PB  - Elsevier Science Inc, New York
T2  - Journal of Dairy Science
T1  - Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative
VL  - 101
IS  - 5
SP  - 3859
EP  - 3865
DO  - 10.3168/jds.2017-13714
UR  - Kon_3471
ER  - 
@article{
author = "Bukvicki, Danka and Giweli, Abdulhmid and Stojković, Dejan and Vujisić, Ljubodrag V. and Tešević, Vele and Nikolić, Miloš and Soković, Marina and Marin, Petar D.",
year = "2018",
abstract = "The essential oil of Thymus algeriensis was analyzed as a potential preservative in soft cheese. We developed a novel method to test the preserving properties of essential oil in soft cheese. Contamination incidence of Penicillium aurantiogriseum was absent after 30 d of storage at 4 degrees C with 25 mu L of essential oil added. The antimicrobial activity was tested against 8 bacteria and 8 fungi. Thymus algeriensis oil showed inhibitory activity against tested bacteria at 0.03 to 0.09 mg/mL, and bactericidal activity was achieved at 0.05 to 0.15 mg/mL. For antifungal activity, minimum inhibitory concentrations ranged between 0.01 and 0.04 mg/mL and minimum fungicidal concentrations between 0.01 and 0.04 mg/mL. Furthermore, the oil was also screened for antiradical activity using the 1,1-diphenyl-2-picrylhydrazyl assay. The results showed that the oil was active and achieved half-maximal inhibitory activity at 0.132 mg/mL. We used gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectrometry to investigate the volatile compounds from the oil. Carvacrol was identified as the main compound in the oil, represented by 80.9% of the total constituents, followed by p-cymene (7.7%).",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Dairy Science",
title = "Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative",
volume = "101",
number = "5",
pages = "3859-3865",
doi = "10.3168/jds.2017-13714",
url = "Kon_3471"
}
Bukvicki, D., Giweli, A., Stojković, D., Vujisić, L. V., Tešević, V., Nikolić, M., Soković, M.,& Marin, P. D.. (2018). Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative. in Journal of Dairy Science
Elsevier Science Inc, New York., 101(5), 3859-3865.
https://doi.org/10.3168/jds.2017-13714
Kon_3471
Bukvicki D, Giweli A, Stojković D, Vujisić LV, Tešević V, Nikolić M, Soković M, Marin PD. Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative. in Journal of Dairy Science. 2018;101(5):3859-3865.
doi:10.3168/jds.2017-13714
Kon_3471 .
Bukvicki, Danka, Giweli, Abdulhmid, Stojković, Dejan, Vujisić, Ljubodrag V., Tešević, Vele, Nikolić, Miloš, Soković, Marina, Marin, Petar D., "Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative" in Journal of Dairy Science, 101, no. 5 (2018):3859-3865,
https://doi.org/10.3168/jds.2017-13714 .,
Kon_3471 .
1
11
10
11

Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps

Ćilerdžić, Jasmina; Sofrenić, Ivana V.; Tešević, Vele; Brčeski, Ilija; Duletić-Laušević, Sonja; Vukojević, Jelena; Stajić, Mirjana

(Wiley-V C H Verlag Gmbh, Weinheim, 2018)

TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Sofrenić, Ivana V.
AU  - Tešević, Vele
AU  - Brčeski, Ilija
AU  - Duletić-Laušević, Sonja
AU  - Vukojević, Jelena
AU  - Stajić, Mirjana
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2153
AB  - Various neurodegenerative diseases are the main challenges to the modern medicine and there is a great need for novel, natural, neuroprotective agents. Ganoderma lucidum is a well-known medicinal mushroom, which health benefits have been confirmed by numerous studies. As demand for its basidiocarps is increased and traditional cultivation on hardwoods is not environmentally friendly and economically justified, finding of alternative substrates is necessary. The aim of the study was to assess the effect of alternative cultivation substrates on the chemical profile of G.lucidum basidiocarps and their capacity to inhibit acetylcholinesterase and tyrosinase, which higher activity is directly associated with neurodegenerative processes. Extracts of basidiocarps cultivated on alternative substrates, especially on clear wheat straw, showed significantly higher inhibition capacities than extracts of commercially-grown ones. These extracts were considerably different chemically from commercial basidiocarps extracts and even nine new compounds were isolated from them. Our results suggest that cultivation substrate greatly affect the chemical profile and neuroprotective capacity of obtained basidiocarps and wheat straw is a promising cultivation substrate.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry and Biodiversity
T1  - Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps
VL  - 15
IS  - 5
DO  - 10.1002/cbdv.201800036
UR  - Kon_3484
ER  - 
@article{
author = "Ćilerdžić, Jasmina and Sofrenić, Ivana V. and Tešević, Vele and Brčeski, Ilija and Duletić-Laušević, Sonja and Vukojević, Jelena and Stajić, Mirjana",
year = "2018",
abstract = "Various neurodegenerative diseases are the main challenges to the modern medicine and there is a great need for novel, natural, neuroprotective agents. Ganoderma lucidum is a well-known medicinal mushroom, which health benefits have been confirmed by numerous studies. As demand for its basidiocarps is increased and traditional cultivation on hardwoods is not environmentally friendly and economically justified, finding of alternative substrates is necessary. The aim of the study was to assess the effect of alternative cultivation substrates on the chemical profile of G.lucidum basidiocarps and their capacity to inhibit acetylcholinesterase and tyrosinase, which higher activity is directly associated with neurodegenerative processes. Extracts of basidiocarps cultivated on alternative substrates, especially on clear wheat straw, showed significantly higher inhibition capacities than extracts of commercially-grown ones. These extracts were considerably different chemically from commercial basidiocarps extracts and even nine new compounds were isolated from them. Our results suggest that cultivation substrate greatly affect the chemical profile and neuroprotective capacity of obtained basidiocarps and wheat straw is a promising cultivation substrate.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry and Biodiversity",
title = "Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps",
volume = "15",
number = "5",
doi = "10.1002/cbdv.201800036",
url = "Kon_3484"
}
Ćilerdžić, J., Sofrenić, I. V., Tešević, V., Brčeski, I., Duletić-Laušević, S., Vukojević, J.,& Stajić, M.. (2018). Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps. in Chemistry and Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 15(5).
https://doi.org/10.1002/cbdv.201800036
Kon_3484
Ćilerdžić J, Sofrenić IV, Tešević V, Brčeski I, Duletić-Laušević S, Vukojević J, Stajić M. Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps. in Chemistry and Biodiversity. 2018;15(5).
doi:10.1002/cbdv.201800036
Kon_3484 .
Ćilerdžić, Jasmina, Sofrenić, Ivana V., Tešević, Vele, Brčeski, Ilija, Duletić-Laušević, Sonja, Vukojević, Jelena, Stajić, Mirjana, "Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps" in Chemistry and Biodiversity, 15, no. 5 (2018),
https://doi.org/10.1002/cbdv.201800036 .,
Kon_3484 .
4
14
11
12

Potential of selected micromycetes for wheat straw degradation

Galić, Milica; Ćilerdžić, Jasmina; Vukojević, Jelena; Stajić, Mirjana; Brčeski, Ilija

(2018)

TY  - JOUR
AU  - Galić, Milica
AU  - Ćilerdžić, Jasmina
AU  - Vukojević, Jelena
AU  - Stajić, Mirjana
AU  - Brčeski, Ilija
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/357
AB  - For the last several years, there is an increasing research interest for lignocellulosic biomass because of its renewable nature. Wheat straw, as one of the most abundant plant wastes, could potentially be transformed into various high valued products (food, feed, paper, biofuel). Micromycetes play an important role in lignocellulose conversion owing to their powerfull enzymatic system. They posses different potentials to synthetise lignocelullolytic enzymes and degrade biomass. Therefore, the objectives of this study were determination of Mn-oxidising peroxidases and laccases activities and extent of wheat straw depolymerisation during solid-state fermentation by selected micromycetes species/strains. The highest Mn-dependent-and Mn-independent peroxidases activities were noted in Clonostachys rosea BEOFB 1610m on day 14 of cultivation (210.23 and 303.03 U l–1, respectively), while Alternaria sp. BEOFB 202m was the unique producer of laccase which maximum activity (1558.59 U l–1) was observed after 7 days of wheat straw fermentation. After 21 days of wheat straw depolymerisation, the highest level of lignin degradation was caused by C. rosea BEOFB 1610m (13.67%), while Alternaria sp. BEOFB 202m was the most efficient hemicellulose and cellulose degrader (38.1 and 29.8%, respectively). These data demonstrate that studied fungal species/strains could potentially be used in various biotechnological processes for the plant raw materials transformation. © 2018, Scibulcom Ltd. All rights reserved.
T2  - Journal of Environmental Protection and Ecology
T1  - Potential of selected micromycetes for wheat straw degradation
VL  - 19
IS  - 3
SP  - 1116
EP  - 1122
UR  - Kon_1328
ER  - 
@article{
author = "Galić, Milica and Ćilerdžić, Jasmina and Vukojević, Jelena and Stajić, Mirjana and Brčeski, Ilija",
year = "2018",
abstract = "For the last several years, there is an increasing research interest for lignocellulosic biomass because of its renewable nature. Wheat straw, as one of the most abundant plant wastes, could potentially be transformed into various high valued products (food, feed, paper, biofuel). Micromycetes play an important role in lignocellulose conversion owing to their powerfull enzymatic system. They posses different potentials to synthetise lignocelullolytic enzymes and degrade biomass. Therefore, the objectives of this study were determination of Mn-oxidising peroxidases and laccases activities and extent of wheat straw depolymerisation during solid-state fermentation by selected micromycetes species/strains. The highest Mn-dependent-and Mn-independent peroxidases activities were noted in Clonostachys rosea BEOFB 1610m on day 14 of cultivation (210.23 and 303.03 U l–1, respectively), while Alternaria sp. BEOFB 202m was the unique producer of laccase which maximum activity (1558.59 U l–1) was observed after 7 days of wheat straw fermentation. After 21 days of wheat straw depolymerisation, the highest level of lignin degradation was caused by C. rosea BEOFB 1610m (13.67%), while Alternaria sp. BEOFB 202m was the most efficient hemicellulose and cellulose degrader (38.1 and 29.8%, respectively). These data demonstrate that studied fungal species/strains could potentially be used in various biotechnological processes for the plant raw materials transformation. © 2018, Scibulcom Ltd. All rights reserved.",
journal = "Journal of Environmental Protection and Ecology",
title = "Potential of selected micromycetes for wheat straw degradation",
volume = "19",
number = "3",
pages = "1116-1122",
url = "Kon_1328"
}
Galić, M., Ćilerdžić, J., Vukojević, J., Stajić, M.,& Brčeski, I.. (2018). Potential of selected micromycetes for wheat straw degradation. in Journal of Environmental Protection and Ecology, 19(3), 1116-1122.
Kon_1328
Galić M, Ćilerdžić J, Vukojević J, Stajić M, Brčeski I. Potential of selected micromycetes for wheat straw degradation. in Journal of Environmental Protection and Ecology. 2018;19(3):1116-1122.
Kon_1328 .
Galić, Milica, Ćilerdžić, Jasmina, Vukojević, Jelena, Stajić, Mirjana, Brčeski, Ilija, "Potential of selected micromycetes for wheat straw degradation" in Journal of Environmental Protection and Ecology, 19, no. 3 (2018):1116-1122,
Kon_1328 .

Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor

Ćilerdžić, Jasmina; Galić, Milica; Ivanović, Žarko; Brčeski, Ilija; Vukojević, Jelena; Stajić, Mirjana

(2018)

TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Galić, Milica
AU  - Ivanović, Žarko
AU  - Brčeski, Ilija
AU  - Vukojević, Jelena
AU  - Stajić, Mirjana
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/346
AB  - Biological pretreatment of the lignocellulosic residues, in which white-rot fungi have a crucial role, has many advantages compared to the chemical, physical, and physico-chemical methods of delignification and therefore attracts increasing scientific attention. Regarding the fact that properties and capacities of the ligninolytic enzymes of Daedaleopsis spp. are still unknown, the aim of this study was to research how nitrogen sources and inducers affect the potential of Daedaleopsis confragosa and Daedaleopsis tricolor to degrade cherry sawdust. NH4NO3, (NH4)2SO4, and peptone were tested as nitrogen sources, while veratryl alcohol, p-anisidine, vanillic acid, and phenylmethylsulfonyl fluoride were the studied inducers. As Mn-dependent peroxidase and laccase were the leader enzymes and cherry sawdust/peptone medium the best stimulator of their activities, the effect of inducers on delignification potential of these species was studied during fermentation of that substrate. Veratryl alcohol was the best stimulator of laccase and phenylmethylsulfonyl fluoride of Mn-dependent peroxidase activity (27,610.0 and 1338.4 U/L, respectively). These inducers also increased cherry sawdust delignification selectivity, particularly in D. tricolor in the presence of phenylmethylsulfonyl fluoride (lignin:hemicellulose:cellulose = 32.1%:0.9%:11.7%). Owing to the presented results, studied species could have an important role in the phase of lignocellulose pretreatment in various biotechnological processes. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
T2  - Applied Biochemistry and Biotechnology
T1  - Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor
DO  - 10.1007/s12010-018-2884-2
UR  - Kon_1317
ER  - 
@article{
author = "Ćilerdžić, Jasmina and Galić, Milica and Ivanović, Žarko and Brčeski, Ilija and Vukojević, Jelena and Stajić, Mirjana",
year = "2018",
abstract = "Biological pretreatment of the lignocellulosic residues, in which white-rot fungi have a crucial role, has many advantages compared to the chemical, physical, and physico-chemical methods of delignification and therefore attracts increasing scientific attention. Regarding the fact that properties and capacities of the ligninolytic enzymes of Daedaleopsis spp. are still unknown, the aim of this study was to research how nitrogen sources and inducers affect the potential of Daedaleopsis confragosa and Daedaleopsis tricolor to degrade cherry sawdust. NH4NO3, (NH4)2SO4, and peptone were tested as nitrogen sources, while veratryl alcohol, p-anisidine, vanillic acid, and phenylmethylsulfonyl fluoride were the studied inducers. As Mn-dependent peroxidase and laccase were the leader enzymes and cherry sawdust/peptone medium the best stimulator of their activities, the effect of inducers on delignification potential of these species was studied during fermentation of that substrate. Veratryl alcohol was the best stimulator of laccase and phenylmethylsulfonyl fluoride of Mn-dependent peroxidase activity (27,610.0 and 1338.4 U/L, respectively). These inducers also increased cherry sawdust delignification selectivity, particularly in D. tricolor in the presence of phenylmethylsulfonyl fluoride (lignin:hemicellulose:cellulose = 32.1%:0.9%:11.7%). Owing to the presented results, studied species could have an important role in the phase of lignocellulose pretreatment in various biotechnological processes. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.",
journal = "Applied Biochemistry and Biotechnology",
title = "Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor",
doi = "10.1007/s12010-018-2884-2",
url = "Kon_1317"
}
Ćilerdžić, J., Galić, M., Ivanović, Ž., Brčeski, I., Vukojević, J.,& Stajić, M.. (2018). Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor. in Applied Biochemistry and Biotechnology.
https://doi.org/10.1007/s12010-018-2884-2
Kon_1317
Ćilerdžić J, Galić M, Ivanović Ž, Brčeski I, Vukojević J, Stajić M. Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor. in Applied Biochemistry and Biotechnology. 2018;.
doi:10.1007/s12010-018-2884-2
Kon_1317 .
Ćilerdžić, Jasmina, Galić, Milica, Ivanović, Žarko, Brčeski, Ilija, Vukojević, Jelena, Stajić, Mirjana, "Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor" in Applied Biochemistry and Biotechnology (2018),
https://doi.org/10.1007/s12010-018-2884-2 .,
Kon_1317 .
2
2
2

Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia

Knežević, Aleksandar; Stajić, Mirjana; Sofrenić, Ivana V.; Stanojković, Tatjana; Milovanović, Ivan; Tešević, Vele; Vukojević, Jelena

(Public Library Science, San Francisco, 2018)

TY  - JOUR
AU  - Knežević, Aleksandar
AU  - Stajić, Mirjana
AU  - Sofrenić, Ivana V.
AU  - Stanojković, Tatjana
AU  - Milovanović, Ivan
AU  - Tešević, Vele
AU  - Vukojević, Jelena
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2211
AB  - In a last few decades mushrooms are increasingly attracting attention as functional food and sources of biologically active compounds. Several Trametes species have been used for centuries in traditional medicine of East Asia cultures, but only T. versicolorwas studied sufficiently while there are less substantial data about medicinal properties of other species. Trametes versicolor, T. hirsuta and T. gibbosa were the species tested for biological activities. Antifungal potentials of extracts were assessed for clinical strains of selected Candida and Aspergillus species. ABTS and FRAP assays were used to evaluate antioxidant capacities of studied extracts. Cytotoxic activity was determined against human cervix and lung adenocarcinoma and colon carcinoma cell lines. Antineurodegenerative activity was assessed by determining the rate of acetylcholinesterase and tyrosinase activity. The presence of metabolites in extracts of mycelia and basidiocarps of studied Trametes species was analyzed by H-1 NMR spectroscopy. Studied extracts showed low antifungal potential in comparison with ketoconazole. Basidiocarp extracts were more effective ABTS(+) scavengers and Fe2+ reducers than mycelium ones but less effective in comparison with L-ascorbic acid. Results showed that mycelium extracts had stronger cytotoxic effects against three cancer cell lines than basidiocarp ones, and that cervix adenocarcinoma cells were the most sensitive to the extracts and commercial cytostatics. T. versicolor mycelium extract was the most effective inhibitor of acetylcholinesterase activity but double weaker than galantamine, and T. gibbosa mycelium extract was significantly better inhibitor of tyrosinase activity than kojic acid for 40.9%. Chemical analysis indicated strong synergistic action of triterpenes, sugars and polyphenols in applied assays. The results suggest that tested Trametes species have significant medicinal potentials which could be attributed to antioxidative and cytotoxic activity. Additionally both, basidiocarps and mycelia extracts can strongly inhibit activity of acetylcholinesterase and tyrosinase.
PB  - Public Library Science, San Francisco
T2  - PLoS One / Public Library of Science
T1  - Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia
VL  - 13
IS  - 8
DO  - 10.1371/journal.pone.0203064
UR  - Kon_3542
ER  - 
@article{
author = "Knežević, Aleksandar and Stajić, Mirjana and Sofrenić, Ivana V. and Stanojković, Tatjana and Milovanović, Ivan and Tešević, Vele and Vukojević, Jelena",
year = "2018",
abstract = "In a last few decades mushrooms are increasingly attracting attention as functional food and sources of biologically active compounds. Several Trametes species have been used for centuries in traditional medicine of East Asia cultures, but only T. versicolorwas studied sufficiently while there are less substantial data about medicinal properties of other species. Trametes versicolor, T. hirsuta and T. gibbosa were the species tested for biological activities. Antifungal potentials of extracts were assessed for clinical strains of selected Candida and Aspergillus species. ABTS and FRAP assays were used to evaluate antioxidant capacities of studied extracts. Cytotoxic activity was determined against human cervix and lung adenocarcinoma and colon carcinoma cell lines. Antineurodegenerative activity was assessed by determining the rate of acetylcholinesterase and tyrosinase activity. The presence of metabolites in extracts of mycelia and basidiocarps of studied Trametes species was analyzed by H-1 NMR spectroscopy. Studied extracts showed low antifungal potential in comparison with ketoconazole. Basidiocarp extracts were more effective ABTS(+) scavengers and Fe2+ reducers than mycelium ones but less effective in comparison with L-ascorbic acid. Results showed that mycelium extracts had stronger cytotoxic effects against three cancer cell lines than basidiocarp ones, and that cervix adenocarcinoma cells were the most sensitive to the extracts and commercial cytostatics. T. versicolor mycelium extract was the most effective inhibitor of acetylcholinesterase activity but double weaker than galantamine, and T. gibbosa mycelium extract was significantly better inhibitor of tyrosinase activity than kojic acid for 40.9%. Chemical analysis indicated strong synergistic action of triterpenes, sugars and polyphenols in applied assays. The results suggest that tested Trametes species have significant medicinal potentials which could be attributed to antioxidative and cytotoxic activity. Additionally both, basidiocarps and mycelia extracts can strongly inhibit activity of acetylcholinesterase and tyrosinase.",
publisher = "Public Library Science, San Francisco",
journal = "PLoS One / Public Library of Science",
title = "Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia",
volume = "13",
number = "8",
doi = "10.1371/journal.pone.0203064",
url = "Kon_3542"
}
Knežević, A., Stajić, M., Sofrenić, I. V., Stanojković, T., Milovanović, I., Tešević, V.,& Vukojević, J.. (2018). Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia. in PLoS One / Public Library of Science
Public Library Science, San Francisco., 13(8).
https://doi.org/10.1371/journal.pone.0203064
Kon_3542
Knežević A, Stajić M, Sofrenić IV, Stanojković T, Milovanović I, Tešević V, Vukojević J. Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia. in PLoS One / Public Library of Science. 2018;13(8).
doi:10.1371/journal.pone.0203064
Kon_3542 .
Knežević, Aleksandar, Stajić, Mirjana, Sofrenić, Ivana V., Stanojković, Tatjana, Milovanović, Ivan, Tešević, Vele, Vukojević, Jelena, "Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia" in PLoS One / Public Library of Science, 13, no. 8 (2018),
https://doi.org/10.1371/journal.pone.0203064 .,
Kon_3542 .
5
14
11
15

Supplementary material for the article: Knežević, A.; Stajić, M.; Sofrenić, I.; Stanojković, T.; Milovanović, I.; Tešević, V.; Vukojević, J. Antioxidative, Antifungal, Cytotoxic and Antineurodegenerative Activity of Selected Trametes Species from Serbia. PLoS ONE 2018, 13 (8). https://doi.org/10.1371/journal.pone.0203064

Knežević, Aleksandar; Stajić, Mirjana; Sofrenić, Ivana V.; Stanojković, Tatjana; Milovanović, Ivan; Tešević, Vele; Vukojević, Jelena

(Public Library Science, San Francisco, 2018)

TY  - DATA
AU  - Knežević, Aleksandar
AU  - Stajić, Mirjana
AU  - Sofrenić, Ivana V.
AU  - Stanojković, Tatjana
AU  - Milovanović, Ivan
AU  - Tešević, Vele
AU  - Vukojević, Jelena
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3169
PB  - Public Library Science, San Francisco
T2  - PLoS One / Public Library of Science
T1  - Supplementary material for the article: Knežević, A.; Stajić, M.; Sofrenić, I.; Stanojković, T.; Milovanović, I.; Tešević, V.; Vukojević, J. Antioxidative, Antifungal, Cytotoxic and Antineurodegenerative Activity of Selected Trametes Species from Serbia. PLoS ONE 2018, 13 (8). https://doi.org/10.1371/journal.pone.0203064
ER  - 
@misc{
author = "Knežević, Aleksandar and Stajić, Mirjana and Sofrenić, Ivana V. and Stanojković, Tatjana and Milovanović, Ivan and Tešević, Vele and Vukojević, Jelena",
year = "2018",
publisher = "Public Library Science, San Francisco",
journal = "PLoS One / Public Library of Science",
title = "Supplementary material for the article: Knežević, A.; Stajić, M.; Sofrenić, I.; Stanojković, T.; Milovanović, I.; Tešević, V.; Vukojević, J. Antioxidative, Antifungal, Cytotoxic and Antineurodegenerative Activity of Selected Trametes Species from Serbia. PLoS ONE 2018, 13 (8). https://doi.org/10.1371/journal.pone.0203064"
}
Knežević, A., Stajić, M., Sofrenić, I. V., Stanojković, T., Milovanović, I., Tešević, V.,& Vukojević, J.. (2018). Supplementary material for the article: Knežević, A.; Stajić, M.; Sofrenić, I.; Stanojković, T.; Milovanović, I.; Tešević, V.; Vukojević, J. Antioxidative, Antifungal, Cytotoxic and Antineurodegenerative Activity of Selected Trametes Species from Serbia. PLoS ONE 2018, 13 (8). https://doi.org/10.1371/journal.pone.0203064. in PLoS One / Public Library of Science
Public Library Science, San Francisco..
Knežević A, Stajić M, Sofrenić IV, Stanojković T, Milovanović I, Tešević V, Vukojević J. Supplementary material for the article: Knežević, A.; Stajić, M.; Sofrenić, I.; Stanojković, T.; Milovanović, I.; Tešević, V.; Vukojević, J. Antioxidative, Antifungal, Cytotoxic and Antineurodegenerative Activity of Selected Trametes Species from Serbia. PLoS ONE 2018, 13 (8). https://doi.org/10.1371/journal.pone.0203064. in PLoS One / Public Library of Science. 2018;..
Knežević, Aleksandar, Stajić, Mirjana, Sofrenić, Ivana V., Stanojković, Tatjana, Milovanović, Ivan, Tešević, Vele, Vukojević, Jelena, "Supplementary material for the article: Knežević, A.; Stajić, M.; Sofrenić, I.; Stanojković, T.; Milovanović, I.; Tešević, V.; Vukojević, J. Antioxidative, Antifungal, Cytotoxic and Antineurodegenerative Activity of Selected Trametes Species from Serbia. PLoS ONE 2018, 13 (8). https://doi.org/10.1371/journal.pone.0203064" in PLoS One / Public Library of Science (2018).

The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens

Nenadic, Marija; Soković, Marina; Glamočlija, Jasmina; Ćirić, Ana D.; Peric-Mataruga, Vesna; Ilijin, Larisa; Tešević, Vele; Todosijević, Marina; Vujisić, Ljubodrag V.; Vesović, Nikola; Ćurčić, Srećko

(Springer, New York, 2017)

TY  - JOUR
AU  - Nenadic, Marija
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Peric-Mataruga, Vesna
AU  - Ilijin, Larisa
AU  - Tešević, Vele
AU  - Todosijević, Marina
AU  - Vujisić, Ljubodrag V.
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2381
AB  - Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of Calosoma sycophanta against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (Carabus spp., Laemostenus punctatus and Abax parallelepipedus). Aspergillus versicolor proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (Escherichia coli), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of C. sycophanta is investigated and discussed.
PB  - Springer, New York
T2  - Applied Microbiology and Biotechnology
T1  - The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens
VL  - 101
IS  - 3
SP  - 977
EP  - 985
DO  - 10.1007/s00253-016-8082-7
UR  - Kon_3197
ER  - 
@article{
author = "Nenadic, Marija and Soković, Marina and Glamočlija, Jasmina and Ćirić, Ana D. and Peric-Mataruga, Vesna and Ilijin, Larisa and Tešević, Vele and Todosijević, Marina and Vujisić, Ljubodrag V. and Vesović, Nikola and Ćurčić, Srećko",
year = "2017",
abstract = "Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of Calosoma sycophanta against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (Carabus spp., Laemostenus punctatus and Abax parallelepipedus). Aspergillus versicolor proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (Escherichia coli), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of C. sycophanta is investigated and discussed.",
publisher = "Springer, New York",
journal = "Applied Microbiology and Biotechnology",
title = "The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens",
volume = "101",
number = "3",
pages = "977-985",
doi = "10.1007/s00253-016-8082-7",
url = "Kon_3197"
}
Nenadic, M., Soković, M., Glamočlija, J., Ćirić, A. D., Peric-Mataruga, V., Ilijin, L., Tešević, V., Todosijević, M., Vujisić, L. V., Vesović, N.,& Ćurčić, S.. (2017). The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens. in Applied Microbiology and Biotechnology
Springer, New York., 101(3), 977-985.
https://doi.org/10.1007/s00253-016-8082-7
Kon_3197
Nenadic M, Soković M, Glamočlija J, Ćirić AD, Peric-Mataruga V, Ilijin L, Tešević V, Todosijević M, Vujisić LV, Vesović N, Ćurčić S. The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens. in Applied Microbiology and Biotechnology. 2017;101(3):977-985.
doi:10.1007/s00253-016-8082-7
Kon_3197 .
Nenadic, Marija, Soković, Marina, Glamočlija, Jasmina, Ćirić, Ana D., Peric-Mataruga, Vesna, Ilijin, Larisa, Tešević, Vele, Todosijević, Marina, Vujisić, Ljubodrag V., Vesović, Nikola, Ćurčić, Srećko, "The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens" in Applied Microbiology and Biotechnology, 101, no. 3 (2017):977-985,
https://doi.org/10.1007/s00253-016-8082-7 .,
Kon_3197 .
6
5
6

Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes

Nenadic, Marija; Ljaljević-Grbić, Milica; Stupar, Miloš; Vukojević, Jelena; Ćirić, Ana D.; Tešević, Vele; Vujisić, Ljubodrag V.; Todosijević, Marina; Vesović, Nikola; Živković, Nemanja; Ćurčić, Srećko

(Springer Heidelberg, Heidelberg, 2017)

TY  - JOUR
AU  - Nenadic, Marija
AU  - Ljaljević-Grbić, Milica
AU  - Stupar, Miloš
AU  - Vukojević, Jelena
AU  - Ćirić, Ana D.
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Vesović, Nikola
AU  - Živković, Nemanja
AU  - Ćurčić, Srećko
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2474
AB  - The antifungal potential of the pygidial gland secretion of the troglophilic ground beetle Laemostenus punctatus from a cave in Southeastern Serbia against cave-dwelling micromycetes, isolated from the same habitat, has been investigated. Eleven collected samples were analyzed and 32 isolates of cave-dwelling fungi were documented. A total of 14 fungal species were identified as members of the genera Aspergillus, Penicillium, Alternaria, Cladosporium, Rhizopus, Trichoderma, Arthrinium, Aureobasidium, Epicoccum, Talaromyces, and Fusarium. Five isolates were selected for testing the antifungal activity of the pygidial gland secretion : Talaromyces duclauxi, Aspergillus brunneouniseriatus, Penicillium sp., Rhizopus stolonifer, and Trichoderma viride. The microdilution method has been applied to detect minimal inhibitory concentrations (MICs) and minimal fungicidal concentrations (MFCs). The most sensitive isolate was Penicillium sp., while the other isolates demonstrated a high level of resistance to the tested agent. L. punctatus has developed a special mechanism of producing specific compounds that act synergistically within the secretion mixture, which are responsible for the antifungal action against pathogens from the cave. The results open opportunities for further research in the field of ground beetle defense against pathogens, which could have an important application in human medicine, in addition to the environmental impact, primarily.
PB  - Springer Heidelberg, Heidelberg
T2  - Naturwissenschaften
T1  - Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes
VL  - 104
IS  - 5-6
SP  - 52
DO  - 10.1007/s00114-017-1474-4
UR  - Kon_3290
ER  - 
@article{
author = "Nenadic, Marija and Ljaljević-Grbić, Milica and Stupar, Miloš and Vukojević, Jelena and Ćirić, Ana D. and Tešević, Vele and Vujisić, Ljubodrag V. and Todosijević, Marina and Vesović, Nikola and Živković, Nemanja and Ćurčić, Srećko",
year = "2017",
abstract = "The antifungal potential of the pygidial gland secretion of the troglophilic ground beetle Laemostenus punctatus from a cave in Southeastern Serbia against cave-dwelling micromycetes, isolated from the same habitat, has been investigated. Eleven collected samples were analyzed and 32 isolates of cave-dwelling fungi were documented. A total of 14 fungal species were identified as members of the genera Aspergillus, Penicillium, Alternaria, Cladosporium, Rhizopus, Trichoderma, Arthrinium, Aureobasidium, Epicoccum, Talaromyces, and Fusarium. Five isolates were selected for testing the antifungal activity of the pygidial gland secretion : Talaromyces duclauxi, Aspergillus brunneouniseriatus, Penicillium sp., Rhizopus stolonifer, and Trichoderma viride. The microdilution method has been applied to detect minimal inhibitory concentrations (MICs) and minimal fungicidal concentrations (MFCs). The most sensitive isolate was Penicillium sp., while the other isolates demonstrated a high level of resistance to the tested agent. L. punctatus has developed a special mechanism of producing specific compounds that act synergistically within the secretion mixture, which are responsible for the antifungal action against pathogens from the cave. The results open opportunities for further research in the field of ground beetle defense against pathogens, which could have an important application in human medicine, in addition to the environmental impact, primarily.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Naturwissenschaften",
title = "Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes",
volume = "104",
number = "5-6",
pages = "52",
doi = "10.1007/s00114-017-1474-4",
url = "Kon_3290"
}
Nenadic, M., Ljaljević-Grbić, M., Stupar, M., Vukojević, J., Ćirić, A. D., Tešević, V., Vujisić, L. V., Todosijević, M., Vesović, N., Živković, N.,& Ćurčić, S.. (2017). Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes. in Naturwissenschaften
Springer Heidelberg, Heidelberg., 104(5-6), 52.
https://doi.org/10.1007/s00114-017-1474-4
Kon_3290
Nenadic M, Ljaljević-Grbić M, Stupar M, Vukojević J, Ćirić AD, Tešević V, Vujisić LV, Todosijević M, Vesović N, Živković N, Ćurčić S. Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes. in Naturwissenschaften. 2017;104(5-6):52.
doi:10.1007/s00114-017-1474-4
Kon_3290 .
Nenadic, Marija, Ljaljević-Grbić, Milica, Stupar, Miloš, Vukojević, Jelena, Ćirić, Ana D., Tešević, Vele, Vujisić, Ljubodrag V., Todosijević, Marina, Vesović, Nikola, Živković, Nemanja, Ćurčić, Srećko, "Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes" in Naturwissenschaften, 104, no. 5-6 (2017):52,
https://doi.org/10.1007/s00114-017-1474-4 .,
Kon_3290 .
1
5
3
4

Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide

Thiesen, L. C. T.; Sugauara, E. Y. Y.; Tešević, Vele; Glamočlija, Jasmina; Soković, Marina; Goncalves, J. E.; Gazim, Z. C.; Linde, G. A.; Colauto, N. B.

(Funpec-Editora, Ribeirao Preto, 2017)

TY  - JOUR
AU  - Thiesen, L. C. T.
AU  - Sugauara, E. Y. Y.
AU  - Tešević, Vele
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Goncalves, J. E.
AU  - Gazim, Z. C.
AU  - Linde, G. A.
AU  - Colauto, N. B.
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2562
AB  - Brunfelsia genus is traditionally utilized in popular medicine due to its antibacterial and antifungal properties to name but a few. However, studies on the antimicrobial activity of Brunfelsia uniflora flower oleoresin have not been found yet. This study aimed to evaluate the chemical composition and antimicrobial activity of B. uniflora flower oleoresin obtained by supercritical carbon dioxide. Oleoresin from the plant dried flowers was obtained by carbon dioxide, and the chemical composition was analyzed by gas chromatographic-mass spectrometry. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentration (MFC) of this oleoresin for seven bacteria and eight fungi were determined using 96-well microtiter plates. The oleoresin MBC for Bacillus cereus, Enterobacter cloacae, Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, Salmonella enterica, and Staphylococcus aureus ranged from 0.01 to 0.08 mg/mL, whereas the controls streptomycin and ampicillin varied from 0.1 and 0.5 mg/mL. The oleoresin MFC for Aspergillus fumigatus, Aspergillus niger, Aspergillus ochraceus, Aspergillus versicolor, Penicillium funiculosum, Penicillium ochrochloron, Penicillium verrucosum var. cyclopium, and Trichoderma viride varied from 0.01 to 0.08 mg/mL, whereas the controls bifonazole and ketoconazole ranged from 0.2 to 3.5 mg/mL. The oleoresin obtained by supercritical carbon dioxide presented bacteriostatic, bactericidal, fungistatic, and fungicidal activities that were higher than the positive controls streptomycin, ampicillin, bifonazole, and ketoconazole. The high antimicrobial activity was related to the high content of (E, E)-geranyllinalool that composes 21.0% of the oleoresin and a possible synergic action with fatty acid esters that made up 50.5% of the oleoresin. The oleoresin antimicrobial activity against common multiresistant bacteria in severe infectious processes as P. aeruginosa or against toxin-producing fungi such as P. ochrochloron or fungi that are difficult to control such as T. viride suggests the development of promising applications of this product in the food, farming, livestock, and pharmaceutical industry.
PB  - Funpec-Editora, Ribeirao Preto
T2  - Genetics and Molecular Research
T1  - Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide
VL  - 16
IS  - 2
DO  - 10.4238/gmr16029548
UR  - Kon_3378
ER  - 
@article{
author = "Thiesen, L. C. T. and Sugauara, E. Y. Y. and Tešević, Vele and Glamočlija, Jasmina and Soković, Marina and Goncalves, J. E. and Gazim, Z. C. and Linde, G. A. and Colauto, N. B.",
year = "2017",
abstract = "Brunfelsia genus is traditionally utilized in popular medicine due to its antibacterial and antifungal properties to name but a few. However, studies on the antimicrobial activity of Brunfelsia uniflora flower oleoresin have not been found yet. This study aimed to evaluate the chemical composition and antimicrobial activity of B. uniflora flower oleoresin obtained by supercritical carbon dioxide. Oleoresin from the plant dried flowers was obtained by carbon dioxide, and the chemical composition was analyzed by gas chromatographic-mass spectrometry. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentration (MFC) of this oleoresin for seven bacteria and eight fungi were determined using 96-well microtiter plates. The oleoresin MBC for Bacillus cereus, Enterobacter cloacae, Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, Salmonella enterica, and Staphylococcus aureus ranged from 0.01 to 0.08 mg/mL, whereas the controls streptomycin and ampicillin varied from 0.1 and 0.5 mg/mL. The oleoresin MFC for Aspergillus fumigatus, Aspergillus niger, Aspergillus ochraceus, Aspergillus versicolor, Penicillium funiculosum, Penicillium ochrochloron, Penicillium verrucosum var. cyclopium, and Trichoderma viride varied from 0.01 to 0.08 mg/mL, whereas the controls bifonazole and ketoconazole ranged from 0.2 to 3.5 mg/mL. The oleoresin obtained by supercritical carbon dioxide presented bacteriostatic, bactericidal, fungistatic, and fungicidal activities that were higher than the positive controls streptomycin, ampicillin, bifonazole, and ketoconazole. The high antimicrobial activity was related to the high content of (E, E)-geranyllinalool that composes 21.0% of the oleoresin and a possible synergic action with fatty acid esters that made up 50.5% of the oleoresin. The oleoresin antimicrobial activity against common multiresistant bacteria in severe infectious processes as P. aeruginosa or against toxin-producing fungi such as P. ochrochloron or fungi that are difficult to control such as T. viride suggests the development of promising applications of this product in the food, farming, livestock, and pharmaceutical industry.",
publisher = "Funpec-Editora, Ribeirao Preto",
journal = "Genetics and Molecular Research",
title = "Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide",
volume = "16",
number = "2",
doi = "10.4238/gmr16029548",
url = "Kon_3378"
}
Thiesen, L. C. T., Sugauara, E. Y. Y., Tešević, V., Glamočlija, J., Soković, M., Goncalves, J. E., Gazim, Z. C., Linde, G. A.,& Colauto, N. B.. (2017). Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide. in Genetics and Molecular Research
Funpec-Editora, Ribeirao Preto., 16(2).
https://doi.org/10.4238/gmr16029548
Kon_3378
Thiesen LCT, Sugauara EYY, Tešević V, Glamočlija J, Soković M, Goncalves JE, Gazim ZC, Linde GA, Colauto NB. Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide. in Genetics and Molecular Research. 2017;16(2).
doi:10.4238/gmr16029548
Kon_3378 .
Thiesen, L. C. T., Sugauara, E. Y. Y., Tešević, Vele, Glamočlija, Jasmina, Soković, Marina, Goncalves, J. E., Gazim, Z. C., Linde, G. A., Colauto, N. B., "Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide" in Genetics and Molecular Research, 16, no. 2 (2017),
https://doi.org/10.4238/gmr16029548 .,
Kon_3378 .
2
1
1
2

Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus

Stajić, Mirjana; Knezevic, A.; Vukojević, Jelena; Ćilerdžić, Jasmina; Brčeski, Ilija

(Scibulcom Ltd, Sofia, 2017)

TY  - JOUR
AU  - Stajić, Mirjana
AU  - Knezevic, A.
AU  - Vukojević, Jelena
AU  - Ćilerdžić, Jasmina
AU  - Brčeski, Ilija
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2073
AB  - Plant raw materials could be potential sources for fibre production and this biomass could be also transformed in valued food, feed, energy sources (biofuels), and paper pulp in the processes where fungi take the major role. Effectiveness of these processes depends on capacity of the fungal species but also on the presence of trace elements which can also remarkably modulate the enzyme activity and to affect biodegradation processes. Pleurotus ostreatus HAI 493 produced ligninolytic enzymes during solid-state fermentation of grapevine sawdust with significant variability in the activity level depending on presence of Fe, Zn, or Se. Enzyme activities in trace element enriched media showed increasing of laccase activity and decreasing of Mn-oxidising peroxidase activity. The highest enlargement of laccase activity (65.9%) was noted after 10 days of cultivation in the presence of Na2SeO4. The highest inhibitory level of Mn-dependent peroxidase activity (59.6%) was noted in the presence of Na2SeO4.
PB  - Scibulcom Ltd, Sofia
T2  - Journal of Environmental Protection and Ecology
T1  - Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus
VL  - 18
IS  - 4
SP  - 1498
EP  - 1504
UR  - Kon_3404
ER  - 
@article{
author = "Stajić, Mirjana and Knezevic, A. and Vukojević, Jelena and Ćilerdžić, Jasmina and Brčeski, Ilija",
year = "2017",
abstract = "Plant raw materials could be potential sources for fibre production and this biomass could be also transformed in valued food, feed, energy sources (biofuels), and paper pulp in the processes where fungi take the major role. Effectiveness of these processes depends on capacity of the fungal species but also on the presence of trace elements which can also remarkably modulate the enzyme activity and to affect biodegradation processes. Pleurotus ostreatus HAI 493 produced ligninolytic enzymes during solid-state fermentation of grapevine sawdust with significant variability in the activity level depending on presence of Fe, Zn, or Se. Enzyme activities in trace element enriched media showed increasing of laccase activity and decreasing of Mn-oxidising peroxidase activity. The highest enlargement of laccase activity (65.9%) was noted after 10 days of cultivation in the presence of Na2SeO4. The highest inhibitory level of Mn-dependent peroxidase activity (59.6%) was noted in the presence of Na2SeO4.",
publisher = "Scibulcom Ltd, Sofia",
journal = "Journal of Environmental Protection and Ecology",
title = "Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus",
volume = "18",
number = "4",
pages = "1498-1504",
url = "Kon_3404"
}
Stajić, M., Knezevic, A., Vukojević, J., Ćilerdžić, J.,& Brčeski, I.. (2017). Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus. in Journal of Environmental Protection and Ecology
Scibulcom Ltd, Sofia., 18(4), 1498-1504.
Kon_3404
Stajić M, Knezevic A, Vukojević J, Ćilerdžić J, Brčeski I. Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus. in Journal of Environmental Protection and Ecology. 2017;18(4):1498-1504.
Kon_3404 .
Stajić, Mirjana, Knezevic, A., Vukojević, Jelena, Ćilerdžić, Jasmina, Brčeski, Ilija, "Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus" in Journal of Environmental Protection and Ecology, 18, no. 4 (2017):1498-1504,
Kon_3404 .
1

Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe

Ćilerdžić, Jasmina; Galić, Milica; Vukojević, Jelena; Brčeski, Ilija; Stajić, Mirjana

(2017)

TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Galić, Milica
AU  - Vukojević, Jelena
AU  - Brčeski, Ilija
AU  - Stajić, Mirjana
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/321
AB  - Background: Structural component of plant biomass, lignocellulose, is the most abundant renewable resource in nature. Lignin is the most recalcitrant natural aromatic polymer and its degradation presents great challenge. Nowadays, the special attention is given to biological delignification, the process where white-rot fungi take the crucial place owing to strong ligninolytic enzyme system. However, fungal species, even strains, differ in potential to produce high active ligninolytic enzymes and consequently to delignify plant biomass. Therefore, the goals of the study were characterization of Mn-oxidizing peroxidases and laccases of numerous mushrooms as well as determination of their potential to delignify wheat straw, the plant raw material that, according to annual yield, takes the first place in Europe and the second one in the world. Results: During wheat straw fermentation, Lentinus edodes HAI 858 produced the most active Mn-dependent and Mn-independent peroxidases (1443.2 U L-1 and 1045.5 U L-1, respectively), while Pleurotus eryngii HAI 711 was the best laccase producer (7804.3 U L-1). Visualized bends on zymogram confirmed these activities and demonstrated that laccases were the dominant ligninolytic enzymes in the studied species. Ganoderma lucidum BEOFB 435 showed considerable ability to degrade lignin (58.5%) and especially hemicellulose (74.8%), while the cellulose remained almost intact (0.7%). Remarkable selectivity in lignocellulose degradation was also noted in Pleurotus pulmonarius HAI 573 where degraded amounts of lignin, hemicellulose and cellulose were in ratio of 50.4%:15.3%:3.8%. Conclusions: According to the presented results, it can be concluded that white-rot fungi, due to ligninolytic enzymes features and degradation potential, could be important participants in various biotechnological processes including biotransformation of lignocellulose residues/wastes in food, feed, paper and biofuels. © 2017 The Author(s).
T2  - BMC Plant Biology
T1  - Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe
VL  - 17
DO  - 10.1186/s12870-017-1196-y
UR  - Kon_1292
ER  - 
@article{
author = "Ćilerdžić, Jasmina and Galić, Milica and Vukojević, Jelena and Brčeski, Ilija and Stajić, Mirjana",
year = "2017",
abstract = "Background: Structural component of plant biomass, lignocellulose, is the most abundant renewable resource in nature. Lignin is the most recalcitrant natural aromatic polymer and its degradation presents great challenge. Nowadays, the special attention is given to biological delignification, the process where white-rot fungi take the crucial place owing to strong ligninolytic enzyme system. However, fungal species, even strains, differ in potential to produce high active ligninolytic enzymes and consequently to delignify plant biomass. Therefore, the goals of the study were characterization of Mn-oxidizing peroxidases and laccases of numerous mushrooms as well as determination of their potential to delignify wheat straw, the plant raw material that, according to annual yield, takes the first place in Europe and the second one in the world. Results: During wheat straw fermentation, Lentinus edodes HAI 858 produced the most active Mn-dependent and Mn-independent peroxidases (1443.2 U L-1 and 1045.5 U L-1, respectively), while Pleurotus eryngii HAI 711 was the best laccase producer (7804.3 U L-1). Visualized bends on zymogram confirmed these activities and demonstrated that laccases were the dominant ligninolytic enzymes in the studied species. Ganoderma lucidum BEOFB 435 showed considerable ability to degrade lignin (58.5%) and especially hemicellulose (74.8%), while the cellulose remained almost intact (0.7%). Remarkable selectivity in lignocellulose degradation was also noted in Pleurotus pulmonarius HAI 573 where degraded amounts of lignin, hemicellulose and cellulose were in ratio of 50.4%:15.3%:3.8%. Conclusions: According to the presented results, it can be concluded that white-rot fungi, due to ligninolytic enzymes features and degradation potential, could be important participants in various biotechnological processes including biotransformation of lignocellulose residues/wastes in food, feed, paper and biofuels. © 2017 The Author(s).",
journal = "BMC Plant Biology",
title = "Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe",
volume = "17",
doi = "10.1186/s12870-017-1196-y",
url = "Kon_1292"
}
Ćilerdžić, J., Galić, M., Vukojević, J., Brčeski, I.,& Stajić, M.. (2017). Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe. in BMC Plant Biology, 17.
https://doi.org/10.1186/s12870-017-1196-y
Kon_1292
Ćilerdžić J, Galić M, Vukojević J, Brčeski I, Stajić M. Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe. in BMC Plant Biology. 2017;17.
doi:10.1186/s12870-017-1196-y
Kon_1292 .
Ćilerdžić, Jasmina, Galić, Milica, Vukojević, Jelena, Brčeski, Ilija, Stajić, Mirjana, "Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe" in BMC Plant Biology, 17 (2017),
https://doi.org/10.1186/s12870-017-1196-y .,
Kon_1292 .
1
15
18
17

Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa

Bukvicki, Danka; Ćirić, Ana D.; Soković, Marina; Vannini, Lucia; Nissen, Lorenzo; Novaković, Miroslav M.; Vujisić, Ljubodrag V.; Asakawa, Yoshinori; Marin, Petar D.

(Natural Products Inc, Westerville, 2016)

TY  - JOUR
AU  - Bukvicki, Danka
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Vannini, Lucia
AU  - Nissen, Lorenzo
AU  - Novaković, Miroslav M.
AU  - Vujisić, Ljubodrag V.
AU  - Asakawa, Yoshinori
AU  - Marin, Petar D.
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2374
AB  - The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa
VL  - 11
IS  - 12
SP  - 1903
EP  - 1906
UR  - Kon_3190
ER  - 
@article{
author = "Bukvicki, Danka and Ćirić, Ana D. and Soković, Marina and Vannini, Lucia and Nissen, Lorenzo and Novaković, Miroslav M. and Vujisić, Ljubodrag V. and Asakawa, Yoshinori and Marin, Petar D.",
year = "2016",
abstract = "The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa",
volume = "11",
number = "12",
pages = "1903-1906",
url = "Kon_3190"
}
Bukvicki, D., Ćirić, A. D., Soković, M., Vannini, L., Nissen, L., Novaković, M. M., Vujisić, L. V., Asakawa, Y.,& Marin, P. D.. (2016). Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa. in Natural Product Communications
Natural Products Inc, Westerville., 11(12), 1903-1906.
Kon_3190
Bukvicki D, Ćirić AD, Soković M, Vannini L, Nissen L, Novaković MM, Vujisić LV, Asakawa Y, Marin PD. Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa. in Natural Product Communications. 2016;11(12):1903-1906.
Kon_3190 .
Bukvicki, Danka, Ćirić, Ana D., Soković, Marina, Vannini, Lucia, Nissen, Lorenzo, Novaković, Miroslav M., Vujisić, Ljubodrag V., Asakawa, Yoshinori, Marin, Petar D., "Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa" in Natural Product Communications, 11, no. 12 (2016):1903-1906,
Kon_3190 .
4
4

Antimicrobial activity of the pygidial gland secretion of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828) (Insecta: Coleoptera: Carabidae)

Nenadic, M.; Soković, Marina; Glamočlija, Jasmina; Ćirić, Ana D.; Peric-Mataruga, V.; Tešević, Vele; Vujisić, Ljubodrag V.; Todosijević, Marina; Vesović, Nikola; Curcic, S.

(Cambridge Univ Press, Cambridge, 2016)

TY  - JOUR
AU  - Nenadic, M.
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Peric-Mataruga, V.
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Vesović, Nikola
AU  - Curcic, S.
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2274
AB  - The antimicrobial activity of the pygidial gland secretion released by adult individuals of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828), applying microdilution method with the aim to detect minimal inhibitory concentration, minimal bactericidal concentration and minimal fungicidal concentration, has been investigated. In addition, morphology of the pygidial glands is observed. Wehave tested 16 laboratory and clinical strains of human pathogens-eight bacterial both gram-positive and gram-negative species and eight fungal species. The pygidial secretion samples have showed antimicrobial properties against all strains of treated bacteria and fungi. Micrococcus flavus proved to be more resistant compared with other bacterial strains. More significant antimicrobial properties of the secretion are observed against Escherichia coli, which proved to be the most sensitive bacteria. Aspergillus fumigatus proved to be the most resistant, while Penicillium ochrochloron and Penicillium verrucosum var. cyclopium themost sensitive micromycetes. Commercial antibiotics Streptomycin and Ampicillin and antimycotics Ketoconazole and Bifonazole, applied as positive controls, showed higher antibacterial properties for all bacterial and fungal strains, except for P. ochrochloron, which proved to be more resistant on Ketoconazole compared with the pygidial gland secretion of L. (P.) punctatus. Apart from the role in ecological aspects, the antimicrobial properties of the tested secretion possibly might have medical significance in the future.
PB  - Cambridge Univ Press, Cambridge
T2  - Bulletin of Entomological Research
T1  - Antimicrobial activity of the pygidial gland secretion of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828) (Insecta: Coleoptera: Carabidae)
VL  - 106
IS  - 4
SP  - 474
EP  - 480
DO  - 10.1017/S0007485316000109
UR  - Kon_3090
ER  - 
@article{
author = "Nenadic, M. and Soković, Marina and Glamočlija, Jasmina and Ćirić, Ana D. and Peric-Mataruga, V. and Tešević, Vele and Vujisić, Ljubodrag V. and Todosijević, Marina and Vesović, Nikola and Curcic, S.",
year = "2016",
abstract = "The antimicrobial activity of the pygidial gland secretion released by adult individuals of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828), applying microdilution method with the aim to detect minimal inhibitory concentration, minimal bactericidal concentration and minimal fungicidal concentration, has been investigated. In addition, morphology of the pygidial glands is observed. Wehave tested 16 laboratory and clinical strains of human pathogens-eight bacterial both gram-positive and gram-negative species and eight fungal species. The pygidial secretion samples have showed antimicrobial properties against all strains of treated bacteria and fungi. Micrococcus flavus proved to be more resistant compared with other bacterial strains. More significant antimicrobial properties of the secretion are observed against Escherichia coli, which proved to be the most sensitive bacteria. Aspergillus fumigatus proved to be the most resistant, while Penicillium ochrochloron and Penicillium verrucosum var. cyclopium themost sensitive micromycetes. Commercial antibiotics Streptomycin and Ampicillin and antimycotics Ketoconazole and Bifonazole, applied as positive controls, showed higher antibacterial properties for all bacterial and fungal strains, except for P. ochrochloron, which proved to be more resistant on Ketoconazole compared with the pygidial gland secretion of L. (P.) punctatus. Apart from the role in ecological aspects, the antimicrobial properties of the tested secretion possibly might have medical significance in the future.",
publisher = "Cambridge Univ Press, Cambridge",
journal = "Bulletin of Entomological Research",
title = "Antimicrobial activity of the pygidial gland secretion of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828) (Insecta: Coleoptera: Carabidae)",
volume = "106",
number = "4",
pages = "474-480",
doi = "10.1017/S0007485316000109",
url = "Kon_3090"
}
Nenadic, M., Soković, M., Glamočlija, J., Ćirić, A. D., Peric-Mataruga, V., Tešević, V., Vujisić, L. V., Todosijević, M., Vesović, N.,& Curcic, S.. (2016). Antimicrobial activity of the pygidial gland secretion of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828) (Insecta: Coleoptera: Carabidae). in Bulletin of Entomological Research
Cambridge Univ Press, Cambridge., 106(4), 474-480.
https://doi.org/10.1017/S0007485316000109
Kon_3090
Nenadic M, Soković M, Glamočlija J, Ćirić AD, Peric-Mataruga V, Tešević V, Vujisić LV, Todosijević M, Vesović N, Curcic S. Antimicrobial activity of the pygidial gland secretion of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828) (Insecta: Coleoptera: Carabidae). in Bulletin of Entomological Research. 2016;106(4):474-480.
doi:10.1017/S0007485316000109
Kon_3090 .
Nenadic, M., Soković, Marina, Glamočlija, Jasmina, Ćirić, Ana D., Peric-Mataruga, V., Tešević, Vele, Vujisić, Ljubodrag V., Todosijević, Marina, Vesović, Nikola, Curcic, S., "Antimicrobial activity of the pygidial gland secretion of the troglophilic ground beetle Laemostenus (Pristonychus) punctatus (Dejean, 1828) (Insecta: Coleoptera: Carabidae)" in Bulletin of Entomological Research, 106, no. 4 (2016):474-480,
https://doi.org/10.1017/S0007485316000109 .,
Kon_3090 .
1
8
6
5

Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)

Nenadic, Marija; Soković, Marina; Glamočlija, Jasmina; Ćirić, Ana D.; Peric-Mataruga, Vesna; Ilijin, Larisa; Tešević, Vele; Vujisić, Ljubodrag V.; Todosijević, Marina; Vesović, Nikola; Ćurčić, Srećko

(Springer Heidelberg, Heidelberg, 2016)

TY  - JOUR
AU  - Nenadic, Marija
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Peric-Mataruga, Vesna
AU  - Ilijin, Larisa
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/1904
AB  - The antimicrobial properties of the pygidial gland secretions released by the adults of the three ground beetle species, Carabus ullrichii, C. coriaceus, and Abax parallelepipedus, have been tested. Microdilution method was applied for detection of minimal inhibitory concentrations (MICs), minimal bactericidal concentrations (MBCs), and minimal fungicidal concentrations (MFCs). Additionally, morpho-histology of the pygidial glands is investigated. We have tested 16 laboratory and clinical strains of human pathogens-eight bacterial both gram-positive and gram-negative species and eight fungal species. The pygidial secretion samples of C. ullrichii have showed the strongest antimicrobial effect against all strains of treated bacteria and fungi. Staphylococcus aureus, Lysteria monocytogenes, and Salmonella typhimurium proved to be the most sensitive bacterial strains. Penicillium funiculosum proved to be the most sensitive micromycete, while P. ochrochloron and P. verrucosum var. cyclopium the most resistant micromycetes. The pygidial secretion of C. coriaceus has showed antibacterial potential solely against Pseudomonas aeruginosa and antifungal activity against Aspergillus fumigatus, A. versicolor, A. ochraceus, and P. ochrochloron. Antibacterial properties of pygidial gland secretion of A. parallelepipedus were achieved against P. aeruginosa, while antifungal activity was detected against five of the eight tested micromycetes (A. fumigatus, A. versicolor, A. ochraceus, Trichoderma viride, and P. verrucosum var. cyclopium). Commercial antibiotics Streptomycin and Ampicillin and mycotics Ketoconazole and Bifonazole, applied as the positive controls, showed higher antibacterial/antifungal properties for all bacterial and fungal strains. The results of this observation might have a significant impact on the environmental aspects and possible medical purpose in the future.
PB  - Springer Heidelberg, Heidelberg
T2  - Naturwissenschaften
T1  - Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)
VL  - 103
IS  - 3-4
SP  - 34
DO  - 10.1007/s00114-016-1358-z
UR  - Kon_3023
ER  - 
@article{
author = "Nenadic, Marija and Soković, Marina and Glamočlija, Jasmina and Ćirić, Ana D. and Peric-Mataruga, Vesna and Ilijin, Larisa and Tešević, Vele and Vujisić, Ljubodrag V. and Todosijević, Marina and Vesović, Nikola and Ćurčić, Srećko",
year = "2016",
abstract = "The antimicrobial properties of the pygidial gland secretions released by the adults of the three ground beetle species, Carabus ullrichii, C. coriaceus, and Abax parallelepipedus, have been tested. Microdilution method was applied for detection of minimal inhibitory concentrations (MICs), minimal bactericidal concentrations (MBCs), and minimal fungicidal concentrations (MFCs). Additionally, morpho-histology of the pygidial glands is investigated. We have tested 16 laboratory and clinical strains of human pathogens-eight bacterial both gram-positive and gram-negative species and eight fungal species. The pygidial secretion samples of C. ullrichii have showed the strongest antimicrobial effect against all strains of treated bacteria and fungi. Staphylococcus aureus, Lysteria monocytogenes, and Salmonella typhimurium proved to be the most sensitive bacterial strains. Penicillium funiculosum proved to be the most sensitive micromycete, while P. ochrochloron and P. verrucosum var. cyclopium the most resistant micromycetes. The pygidial secretion of C. coriaceus has showed antibacterial potential solely against Pseudomonas aeruginosa and antifungal activity against Aspergillus fumigatus, A. versicolor, A. ochraceus, and P. ochrochloron. Antibacterial properties of pygidial gland secretion of A. parallelepipedus were achieved against P. aeruginosa, while antifungal activity was detected against five of the eight tested micromycetes (A. fumigatus, A. versicolor, A. ochraceus, Trichoderma viride, and P. verrucosum var. cyclopium). Commercial antibiotics Streptomycin and Ampicillin and mycotics Ketoconazole and Bifonazole, applied as the positive controls, showed higher antibacterial/antifungal properties for all bacterial and fungal strains. The results of this observation might have a significant impact on the environmental aspects and possible medical purpose in the future.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Naturwissenschaften",
title = "Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)",
volume = "103",
number = "3-4",
pages = "34",
doi = "10.1007/s00114-016-1358-z",
url = "Kon_3023"
}
Nenadic, M., Soković, M., Glamočlija, J., Ćirić, A. D., Peric-Mataruga, V., Ilijin, L., Tešević, V., Vujisić, L. V., Todosijević, M., Vesović, N.,& Ćurčić, S.. (2016). Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae). in Naturwissenschaften
Springer Heidelberg, Heidelberg., 103(3-4), 34.
https://doi.org/10.1007/s00114-016-1358-z
Kon_3023
Nenadic M, Soković M, Glamočlija J, Ćirić AD, Peric-Mataruga V, Ilijin L, Tešević V, Vujisić LV, Todosijević M, Vesović N, Ćurčić S. Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae). in Naturwissenschaften. 2016;103(3-4):34.
doi:10.1007/s00114-016-1358-z
Kon_3023 .
Nenadic, Marija, Soković, Marina, Glamočlija, Jasmina, Ćirić, Ana D., Peric-Mataruga, Vesna, Ilijin, Larisa, Tešević, Vele, Vujisić, Ljubodrag V., Todosijević, Marina, Vesović, Nikola, Ćurčić, Srećko, "Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)" in Naturwissenschaften, 103, no. 3-4 (2016):34,
https://doi.org/10.1007/s00114-016-1358-z .,
Kon_3023 .
2
13
10
11

Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1

Mileski, Ksenija S.; Ćirić, Ana D.; Trifunović, Snežana S.; Ristić, Mihailo S.; Soković, Marina; Matevski, Vlado S.; Tešević, Vele; Jadranin, Milka; Marin, Petar D.; Džamić, Ana M.

(Royal Soc Chemistry, Cambridge, 2016)

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Ćirić, Ana D.
AU  - Trifunović, Snežana S.
AU  - Ristić, Mihailo S.
AU  - Soković, Marina
AU  - Matevski, Vlado S.
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Džamić, Ana M.
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3521
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food and Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
UR  - Kon_3132
ER  - 
@article{
author = "Mileski, Ksenija S. and Ćirić, Ana D. and Trifunović, Snežana S. and Ristić, Mihailo S. and Soković, Marina and Matevski, Vlado S. and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Džamić, Ana M.",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food and Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k",
url = "Kon_3132"
}
Mileski, K. S., Ćirić, A. D., Trifunović, S. S., Ristić, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Džamić, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k
Kon_3132
Mileski KS, Ćirić AD, Trifunović SS, Ristić MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Džamić AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k
Kon_3132 .
Mileski, Ksenija S., Ćirić, Ana D., Trifunović, Snežana S., Ristić, Mihailo S., Soković, Marina, Matevski, Vlado S., Tešević, Vele, Jadranin, Milka, Marin, Petar D., Džamić, Ana M., "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food and Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k .,
Kon_3132 .
1
8
7
7

Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1

Mileski, Ksenija S.; Ćirić, Ana D.; Trifunović, Snežana S.; Ristić, Mihailo S.; Soković, Marina; Matevski, Vlado S.; Tešević, Vele; Jadranin, Milka; Marin, Petar D.; Džamić, Ana M.

(Royal Soc Chemistry, Cambridge, 2016)

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Ćirić, Ana D.
AU  - Trifunović, Snežana S.
AU  - Ristić, Mihailo S.
AU  - Soković, Marina
AU  - Matevski, Vlado S.
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Džamić, Ana M.
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2316
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food and Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
UR  - Kon_3132
ER  - 
@article{
author = "Mileski, Ksenija S. and Ćirić, Ana D. and Trifunović, Snežana S. and Ristić, Mihailo S. and Soković, Marina and Matevski, Vlado S. and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Džamić, Ana M.",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food and Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k",
url = "Kon_3132"
}
Mileski, K. S., Ćirić, A. D., Trifunović, S. S., Ristić, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Džamić, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k
Kon_3132
Mileski KS, Ćirić AD, Trifunović SS, Ristić MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Džamić AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k
Kon_3132 .
Mileski, Ksenija S., Ćirić, Ana D., Trifunović, Snežana S., Ristić, Mihailo S., Soković, Marina, Matevski, Vlado S., Tešević, Vele, Jadranin, Milka, Marin, Petar D., Džamić, Ana M., "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food and Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k .,
Kon_3132 .
1
8
7
7

Supplementary data for the article: Spasojević, D.; Zmejkoski, D.; Glamočlija, J.; Nikolić, M.; Soković, M.; Milošević, V.; Jarić, I.; Stojanović, M.; Marinković, E.; Barisani-Asenbauer, T.; et al. Lignin Model Compound in Alginate Hydrogel: A Strong Antimicrobial Agent with High Potential in Wound Treatment. International Journal of Antimicrobial Agents 2016, 48 (6), 732–735. https://doi.org/10.1016/j.ijantimicag.2016.08.014

Spasojević, Dragica; Zmejkoski, Danica; Glamoclija, Jasmina; Nikolić, Miloš; Soković, Marina; Milošević, Verica; Jarić, Ivana; Stojanović, Marijana M.; Marinković, Emilija; Barisani-Asenbauer, Talin; Prodanović, Radivoje; Jovanović, Miloš; Radotić, Ksenija

(Elsevier Science Bv, Amsterdam, 2016)

TY  - DATA
AU  - Spasojević, Dragica
AU  - Zmejkoski, Danica
AU  - Glamoclija, Jasmina
AU  - Nikolić, Miloš
AU  - Soković, Marina
AU  - Milošević, Verica
AU  - Jarić, Ivana
AU  - Stojanović, Marijana M.
AU  - Marinković, Emilija
AU  - Barisani-Asenbauer, Talin
AU  - Prodanović, Radivoje
AU  - Jovanović, Miloš
AU  - Radotić, Ksenija
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3560
PB  - Elsevier Science Bv, Amsterdam
T2  - International Journal of Antimicrobial Agents
T1  - Supplementary data for the article: Spasojević, D.; Zmejkoski, D.; Glamočlija, J.; Nikolić, M.; Soković, M.; Milošević, V.; Jarić, I.; Stojanović, M.; Marinković, E.; Barisani-Asenbauer, T.; et al. Lignin Model Compound in Alginate Hydrogel: A Strong Antimicrobial Agent with High Potential in Wound Treatment. International Journal of Antimicrobial Agents 2016, 48 (6), 732–735. https://doi.org/10.1016/j.ijantimicag.2016.08.014
ER  - 
@misc{
author = "Spasojević, Dragica and Zmejkoski, Danica and Glamoclija, Jasmina and Nikolić, Miloš and Soković, Marina and Milošević, Verica and Jarić, Ivana and Stojanović, Marijana M. and Marinković, Emilija and Barisani-Asenbauer, Talin and Prodanović, Radivoje and Jovanović, Miloš and Radotić, Ksenija",
year = "2016",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "International Journal of Antimicrobial Agents",
title = "Supplementary data for the article: Spasojević, D.; Zmejkoski, D.; Glamočlija, J.; Nikolić, M.; Soković, M.; Milošević, V.; Jarić, I.; Stojanović, M.; Marinković, E.; Barisani-Asenbauer, T.; et al. Lignin Model Compound in Alginate Hydrogel: A Strong Antimicrobial Agent with High Potential in Wound Treatment. International Journal of Antimicrobial Agents 2016, 48 (6), 732–735. https://doi.org/10.1016/j.ijantimicag.2016.08.014"
}
Spasojević, D., Zmejkoski, D., Glamoclija, J., Nikolić, M., Soković, M., Milošević, V., Jarić, I., Stojanović, M. M., Marinković, E., Barisani-Asenbauer, T., Prodanović, R., Jovanović, M.,& Radotić, K.. (2016). Supplementary data for the article: Spasojević, D.; Zmejkoski, D.; Glamočlija, J.; Nikolić, M.; Soković, M.; Milošević, V.; Jarić, I.; Stojanović, M.; Marinković, E.; Barisani-Asenbauer, T.; et al. Lignin Model Compound in Alginate Hydrogel: A Strong Antimicrobial Agent with High Potential in Wound Treatment. International Journal of Antimicrobial Agents 2016, 48 (6), 732–735. https://doi.org/10.1016/j.ijantimicag.2016.08.014. in International Journal of Antimicrobial Agents
Elsevier Science Bv, Amsterdam..
Spasojević D, Zmejkoski D, Glamoclija J, Nikolić M, Soković M, Milošević V, Jarić I, Stojanović MM, Marinković E, Barisani-Asenbauer T, Prodanović R, Jovanović M, Radotić K. Supplementary data for the article: Spasojević, D.; Zmejkoski, D.; Glamočlija, J.; Nikolić, M.; Soković, M.; Milošević, V.; Jarić, I.; Stojanović, M.; Marinković, E.; Barisani-Asenbauer, T.; et al. Lignin Model Compound in Alginate Hydrogel: A Strong Antimicrobial Agent with High Potential in Wound Treatment. International Journal of Antimicrobial Agents 2016, 48 (6), 732–735. https://doi.org/10.1016/j.ijantimicag.2016.08.014. in International Journal of Antimicrobial Agents. 2016;..
Spasojević, Dragica, Zmejkoski, Danica, Glamoclija, Jasmina, Nikolić, Miloš, Soković, Marina, Milošević, Verica, Jarić, Ivana, Stojanović, Marijana M., Marinković, Emilija, Barisani-Asenbauer, Talin, Prodanović, Radivoje, Jovanović, Miloš, Radotić, Ksenija, "Supplementary data for the article: Spasojević, D.; Zmejkoski, D.; Glamočlija, J.; Nikolić, M.; Soković, M.; Milošević, V.; Jarić, I.; Stojanović, M.; Marinković, E.; Barisani-Asenbauer, T.; et al. Lignin Model Compound in Alginate Hydrogel: A Strong Antimicrobial Agent with High Potential in Wound Treatment. International Journal of Antimicrobial Agents 2016, 48 (6), 732–735. https://doi.org/10.1016/j.ijantimicag.2016.08.014" in International Journal of Antimicrobial Agents (2016).

Antifungal and antibacterial activities of Petroselinum crispum essential oil

Linde, G. A.; Gazim, Z. C.; Cardoso, B. K.; Jorge, L. F.; Tešević, Vele; Glamočlija, Jasmina; Soković, Marina; Colauto, N. B.

(Funpec-Editora, Ribeirao Preto, 2016)

TY  - JOUR
AU  - Linde, G. A.
AU  - Gazim, Z. C.
AU  - Cardoso, B. K.
AU  - Jorge, L. F.
AU  - Tešević, Vele
AU  - Glamočlija, Jasmina
AU  - Soković, Marina
AU  - Colauto, N. B.
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2323
AB  - Parsley [Petroselinum crispum (Mill.) Fuss] is regarded as an aromatic, culinary, and medicinal plant and is used in the cosmetic, food, and pharmaceutical industries. However, few studies with conflicting results have been conducted on the antimicrobial activity of parsley essential oil. In addition, there have been no reports of essential oil obtained from parsley aerial parts, except seeds, as an alternative natural antimicrobial agent. Also, microorganism resistance is still a challenge for health and food production. Based on the demand for natural products to control microorganisms, and the reevaluation of potential medicinal plants for controlling diseases, the objective of this study was to determine the chemical composition and antibacterial and antifungal activities of parsley essential oil against foodborne diseases and opportunistic pathogens. Seven bacteria and eight fungi were tested. The essential oil major compounds were apiol, myristicin, and beta-phellandrene. Parsley essential oil had bacteriostatic activity against all tested bacteria, mainly Staphylococcus aureus, Listeria monocytogenes, and Salmonella enterica, at similar or lower concentrations than at least one of the controls, and bactericidal activity against all tested bacteria, mainly S. aureus, at similar or lower concentrations than at least one of the controls. This essential oil also had fungistatic activity against all tested fungi, mainly, Penicillium ochrochloron and Trichoderma viride, at lower concentrations than the ketoconazole control and fungicidal activity against all tested fungi at higher concentrations than the controls. Parsley is used in cooking and medicine, and its essential oil is an effective antimicrobial agent.
PB  - Funpec-Editora, Ribeirao Preto
T2  - Genetics and Molecular Research
T1  - Antifungal and antibacterial activities of Petroselinum crispum essential oil
VL  - 15
IS  - 3
DO  - 10.4238/gmr.15038538
UR  - Kon_3139
ER  - 
@article{
author = "Linde, G. A. and Gazim, Z. C. and Cardoso, B. K. and Jorge, L. F. and Tešević, Vele and Glamočlija, Jasmina and Soković, Marina and Colauto, N. B.",
year = "2016",
abstract = "Parsley [Petroselinum crispum (Mill.) Fuss] is regarded as an aromatic, culinary, and medicinal plant and is used in the cosmetic, food, and pharmaceutical industries. However, few studies with conflicting results have been conducted on the antimicrobial activity of parsley essential oil. In addition, there have been no reports of essential oil obtained from parsley aerial parts, except seeds, as an alternative natural antimicrobial agent. Also, microorganism resistance is still a challenge for health and food production. Based on the demand for natural products to control microorganisms, and the reevaluation of potential medicinal plants for controlling diseases, the objective of this study was to determine the chemical composition and antibacterial and antifungal activities of parsley essential oil against foodborne diseases and opportunistic pathogens. Seven bacteria and eight fungi were tested. The essential oil major compounds were apiol, myristicin, and beta-phellandrene. Parsley essential oil had bacteriostatic activity against all tested bacteria, mainly Staphylococcus aureus, Listeria monocytogenes, and Salmonella enterica, at similar or lower concentrations than at least one of the controls, and bactericidal activity against all tested bacteria, mainly S. aureus, at similar or lower concentrations than at least one of the controls. This essential oil also had fungistatic activity against all tested fungi, mainly, Penicillium ochrochloron and Trichoderma viride, at lower concentrations than the ketoconazole control and fungicidal activity against all tested fungi at higher concentrations than the controls. Parsley is used in cooking and medicine, and its essential oil is an effective antimicrobial agent.",
publisher = "Funpec-Editora, Ribeirao Preto",
journal = "Genetics and Molecular Research",
title = "Antifungal and antibacterial activities of Petroselinum crispum essential oil",
volume = "15",
number = "3",
doi = "10.4238/gmr.15038538",
url = "Kon_3139"
}
Linde, G. A., Gazim, Z. C., Cardoso, B. K., Jorge, L. F., Tešević, V., Glamočlija, J., Soković, M.,& Colauto, N. B.. (2016). Antifungal and antibacterial activities of Petroselinum crispum essential oil. in Genetics and Molecular Research
Funpec-Editora, Ribeirao Preto., 15(3).
https://doi.org/10.4238/gmr.15038538
Kon_3139
Linde GA, Gazim ZC, Cardoso BK, Jorge LF, Tešević V, Glamočlija J, Soković M, Colauto NB. Antifungal and antibacterial activities of Petroselinum crispum essential oil. in Genetics and Molecular Research. 2016;15(3).
doi:10.4238/gmr.15038538
Kon_3139 .
Linde, G. A., Gazim, Z. C., Cardoso, B. K., Jorge, L. F., Tešević, Vele, Glamočlija, Jasmina, Soković, Marina, Colauto, N. B., "Antifungal and antibacterial activities of Petroselinum crispum essential oil" in Genetics and Molecular Research, 15, no. 3 (2016),
https://doi.org/10.4238/gmr.15038538 .,
Kon_3139 .
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