TY  - CONF
AU  - Radosavljević, Jelena
AU  - Smiljanić, Katarina
AU  - Vasović, Tamara
AU  - Apostolović, Danijela
AU  - Ćirković-Veličković, Tanja
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5766
AB  - Pollen allergies have tremendous global clinical impact. Diagnosis of allergy in a clinical setting
is based on the use of purified allergens which are considered to be more accurate and sensitive
than crude pollen extracts. Thus, proper identification and characterization of allergens at the
molecular level and production of a recombinant counterpart are of outmost importance for the
efficient use of the current diagnostic tools for allergy. Recombinant allergens are nowadays
produced instead of natural, as isolation of a natural allergen is a troublesome process. Tree
pollens that are most commonly associated with respiratory allergies are produced by birch in the
Northern, Central, and Eastern Europe, and by olive and cypress in the Mediterranean regions.
Accordingly, most research so far has focused on the allergenicity of pollens from birch, olive and
cypress. Allergy to linden pollen has been known, but no allergen has been described from this
source yet. Here we propose cloning and production of the first recombinant linden pollen
allergen that can be used as a marker allergen of linden pollen allergenicity and complement
existing diagnostic allergen-arrays. Also, production of this recombinant allergen has potential to
contribute to the development of novel allergen-diagnostic tools through collaborations with
biotech companies.
PB  - Univerzitet u Beogradu - Hemijski fakultet
C3  - Book of Abstracts of the 3rd Workshop FoodenTwin 2021, Belgrade 15 June
T1  - Production of the protein, probable marker for linden allergy
SP  - 10
EP  - 10
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5766
ER  - 

@conference{
author = "Radosavljević, Jelena and Smiljanić, Katarina and Vasović, Tamara and Apostolović, Danijela and Ćirković-Veličković, Tanja",
year = "2021",
abstract = "Pollen allergies have tremendous global clinical impact. Diagnosis of allergy in a clinical setting
is based on the use of purified allergens which are considered to be more accurate and sensitive
than crude pollen extracts. Thus, proper identification and characterization of allergens at the
molecular level and production of a recombinant counterpart are of outmost importance for the
efficient use of the current diagnostic tools for allergy. Recombinant allergens are nowadays
produced instead of natural, as isolation of a natural allergen is a troublesome process. Tree
pollens that are most commonly associated with respiratory allergies are produced by birch in the
Northern, Central, and Eastern Europe, and by olive and cypress in the Mediterranean regions.
Accordingly, most research so far has focused on the allergenicity of pollens from birch, olive and
cypress. Allergy to linden pollen has been known, but no allergen has been described from this
source yet. Here we propose cloning and production of the first recombinant linden pollen
allergen that can be used as a marker allergen of linden pollen allergenicity and complement
existing diagnostic allergen-arrays. Also, production of this recombinant allergen has potential to
contribute to the development of novel allergen-diagnostic tools through collaborations with
biotech companies.",
publisher = "Univerzitet u Beogradu - Hemijski fakultet",
journal = "Book of Abstracts of the 3rd Workshop FoodenTwin 2021, Belgrade 15 June",
title = "Production of the protein, probable marker for linden allergy",
pages = "10-10",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5766"
}

Radosavljević, J., Smiljanić, K., Vasović, T., Apostolović, D.,& Ćirković-Veličković, T.. (2021). Production of the protein, probable marker for linden allergy. in Book of Abstracts of the 3rd Workshop FoodenTwin 2021, Belgrade 15 June
Univerzitet u Beogradu - Hemijski fakultet., 10-10.
https://hdl.handle.net/21.15107/rcub_cherry_5766

Radosavljević J, Smiljanić K, Vasović T, Apostolović D, Ćirković-Veličković T. Production of the protein, probable marker for linden allergy. in Book of Abstracts of the 3rd Workshop FoodenTwin 2021, Belgrade 15 June. 2021;:10-10.
https://hdl.handle.net/21.15107/rcub_cherry_5766 .

Radosavljević, Jelena, Smiljanić, Katarina, Vasović, Tamara, Apostolović, Danijela, Ćirković-Veličković, Tanja, "Production of the protein, probable marker for linden allergy" in Book of Abstracts of the 3rd Workshop FoodenTwin 2021, Belgrade 15 June (2021):10-10,
https://hdl.handle.net/21.15107/rcub_cherry_5766 .