Italian Ministry of Education (MIUR)

Link to this page

Italian Ministry of Education (MIUR)

Authors

Publications

Fullerene Unsymmetrical Bis-Adducts as Models for Novel Peptidomimetics

Milić, Dragana; Prato, Maurizio

(Wiley-V C H Verlag Gmbh, Weinheim, 2010)

TY  - JOUR
AU  - Milić, Dragana
AU  - Prato, Maurizio
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1044
AB  - Two classes of unsymmetrical, orthogonally protected bis-fulleropyrrohdine amino acids have been prepared as models for fullerene-based peptidomimetics with the carbon sphere inserted into the peptide backbone Two successive [3+2] cycloadditions of azomethine ylides (thermally generated from formaldehyde and the corresponding orthogonally protected glycino-amines and -acids) to C(60) afforded NHFmoc/CO(2)tBu and NHBoc/CO(2)Me fulleropyrrolidine couples, offering the possibility of selective deprotection under both acidic and basic conditions In both classes of unsymmetrical bis-adducts, the distribution of all the trans (t(1)-t(4)) and equatorial (e' and e '') isomers was quite similar except. for the t(3) NHBoc/CO(2)Me compound, which rapidly decomposed during chromatography All compounds were characterized by UV/Vis, (1)H and (13)C NMR spectroscopy, and mass spectrometry
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - European Journal of Organic Chemistry
T1  - Fullerene Unsymmetrical Bis-Adducts as Models for Novel Peptidomimetics
IS  - 3
SP  - 476
EP  - 483
DO  - 10.1002/ejoc.200900791
ER  - 
@article{
author = "Milić, Dragana and Prato, Maurizio",
year = "2010",
abstract = "Two classes of unsymmetrical, orthogonally protected bis-fulleropyrrohdine amino acids have been prepared as models for fullerene-based peptidomimetics with the carbon sphere inserted into the peptide backbone Two successive [3+2] cycloadditions of azomethine ylides (thermally generated from formaldehyde and the corresponding orthogonally protected glycino-amines and -acids) to C(60) afforded NHFmoc/CO(2)tBu and NHBoc/CO(2)Me fulleropyrrolidine couples, offering the possibility of selective deprotection under both acidic and basic conditions In both classes of unsymmetrical bis-adducts, the distribution of all the trans (t(1)-t(4)) and equatorial (e' and e '') isomers was quite similar except. for the t(3) NHBoc/CO(2)Me compound, which rapidly decomposed during chromatography All compounds were characterized by UV/Vis, (1)H and (13)C NMR spectroscopy, and mass spectrometry",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "European Journal of Organic Chemistry",
title = "Fullerene Unsymmetrical Bis-Adducts as Models for Novel Peptidomimetics",
number = "3",
pages = "476-483",
doi = "10.1002/ejoc.200900791"
}
Milić, D.,& Prato, M.. (2010). Fullerene Unsymmetrical Bis-Adducts as Models for Novel Peptidomimetics. in European Journal of Organic Chemistry
Wiley-V C H Verlag Gmbh, Weinheim.(3), 476-483.
https://doi.org/10.1002/ejoc.200900791
Milić D, Prato M. Fullerene Unsymmetrical Bis-Adducts as Models for Novel Peptidomimetics. in European Journal of Organic Chemistry. 2010;(3):476-483.
doi:10.1002/ejoc.200900791 .
Milić, Dragana, Prato, Maurizio, "Fullerene Unsymmetrical Bis-Adducts as Models for Novel Peptidomimetics" in European Journal of Organic Chemistry, no. 3 (2010):476-483,
https://doi.org/10.1002/ejoc.200900791 . .
20
17
19
19