Sinteze, fizičke, strukturne i biološke karakteristike novih kompleksnih jedenjenja

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Sinteze, fizičke, strukturne i biološke karakteristike novih kompleksnih jedenjenja (en)
Синтезе, физичке, структурне и биолошке карактеристике нових комплексних једењења (sr)
Sinteze, fizičke, strukturne i biološke karakteristike novih kompleksnih jedenjenja (sr_RS)
Authors

Publications

Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids

Joksović, Milan D.; Bogdanović, Gordana; Kojić, Vesna; Szecsenyi, Katalin Meszaros; Leovac, Vukadin M.; Jakimov, Dimitar; Trifunović, Snežana S.; Marković, Violeta; Joksović, Ljubinka

(Wiley-Blackwell, Malden, 2010)

TY  - JOUR
AU  - Joksović, Milan D.
AU  - Bogdanović, Gordana
AU  - Kojić, Vesna
AU  - Szecsenyi, Katalin Meszaros
AU  - Leovac, Vukadin M.
AU  - Jakimov, Dimitar
AU  - Trifunović, Snežana S.
AU  - Marković, Violeta
AU  - Joksović, Ljubinka
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1097
AB  - New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential.
PB  - Wiley-Blackwell, Malden
T2  - Journal of Heterocyclic Chemistry
T1  - Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids
VL  - 47
IS  - 4
SP  - 850
EP  - 856
DO  - 10.1002/jhet.400
ER  - 
@article{
author = "Joksović, Milan D. and Bogdanović, Gordana and Kojić, Vesna and Szecsenyi, Katalin Meszaros and Leovac, Vukadin M. and Jakimov, Dimitar and Trifunović, Snežana S. and Marković, Violeta and Joksović, Ljubinka",
year = "2010",
abstract = "New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential.",
publisher = "Wiley-Blackwell, Malden",
journal = "Journal of Heterocyclic Chemistry",
title = "Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids",
volume = "47",
number = "4",
pages = "850-856",
doi = "10.1002/jhet.400"
}
Joksović, M. D., Bogdanović, G., Kojić, V., Szecsenyi, K. M., Leovac, V. M., Jakimov, D., Trifunović, S. S., Marković, V.,& Joksović, L.. (2010). Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids. in Journal of Heterocyclic Chemistry
Wiley-Blackwell, Malden., 47(4), 850-856.
https://doi.org/10.1002/jhet.400
Joksović MD, Bogdanović G, Kojić V, Szecsenyi KM, Leovac VM, Jakimov D, Trifunović SS, Marković V, Joksović L. Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids. in Journal of Heterocyclic Chemistry. 2010;47(4):850-856.
doi:10.1002/jhet.400 .
Joksović, Milan D., Bogdanović, Gordana, Kojić, Vesna, Szecsenyi, Katalin Meszaros, Leovac, Vukadin M., Jakimov, Dimitar, Trifunović, Snežana S., Marković, Violeta, Joksović, Ljubinka, "Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids" in Journal of Heterocyclic Chemistry, 47, no. 4 (2010):850-856,
https://doi.org/10.1002/jhet.400 . .
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New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity

Krstić, Milena; Sovilj, Sofija P.; Grgurić-Šipka, Sanja; Evans, Ivana Radosavljevic; Borozan, Sunčica; Santibanez, Juan Francisco; Kocic, Jelena

(Elsevier France-Editions Scientifiques Medicales Elsevier, Paris, 2010)

TY  - JOUR
AU  - Krstić, Milena
AU  - Sovilj, Sofija P.
AU  - Grgurić-Šipka, Sanja
AU  - Evans, Ivana Radosavljevic
AU  - Borozan, Sunčica
AU  - Santibanez, Juan Francisco
AU  - Kocic, Jelena
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1113
AB  - Three new complexes of the general formula L[RuCl(3)(DMSO)(3)] (1-3), where L = chlorpromazine hydrochloride, trifluoroperazine dihydrochloride or thioridazine hydrochloride, were prepared and characterized by elemental analysis and spectroscopic methods (FT-IR, UV-Vis, (1)H NMR and (13)C NMR). In addition, the crystal structure of the complex 2 containing trifluoroperazine dihydrochloride was solved by single crystal X-ray diffraction. The complex crystallizes in the monoclinic system, space group P2(1)/n, with a = 10.4935(7) angstrom, b = 18.6836(12) angstrom, c = 19.9250(13) angstrom, beta = 98.448(2)degrees, V = 3864.0(4) angstrom(3). The structure was refined to the agreement factors of R = 4.79%, R(w) = 11.23%. The effect of three different doses (0.4, 4.5 and 90.4 mu M/kg bw) of complex 2 on superoxide dismutase (SOD) and catalase (CAT) activity was investigated under physiological conditions. Influence on nitrite production (NO(2)(-)) and the level of erythrocytes malondialdehyde (MDA) in rats blood was also evaluated. Complex 2 did not affect the CAT enzyme activity in vivo and did not cause the hydroxyl radicals production. In the 0.4 and 4.5 mu M/kg bw doses it showed almost the same or lower SOD activity and nitrite levels, while the dose of 90.4 mu M/kg bw significantly increased these parameters. Finally, the cytotoxicity of complexes were assayed in four human carcinoma cell lines MCF-7, MDA-MB-453 (breast carcinoma), SW-480 (colon adenocarcinoma) and IM9 (myeloma multiple cells). Antiproliferative activity in vitro with low IC(50) during 48 h of treatment was observed. (C) 2010 Elsevier Masson SAS. All rights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2  - European Journal of Medicinal Chemistry
T1  - New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity
VL  - 45
IS  - 9
SP  - 3669
EP  - 3676
DO  - 10.1016/j.ejmech.2010.05.013
ER  - 
@article{
author = "Krstić, Milena and Sovilj, Sofija P. and Grgurić-Šipka, Sanja and Evans, Ivana Radosavljevic and Borozan, Sunčica and Santibanez, Juan Francisco and Kocic, Jelena",
year = "2010",
abstract = "Three new complexes of the general formula L[RuCl(3)(DMSO)(3)] (1-3), where L = chlorpromazine hydrochloride, trifluoroperazine dihydrochloride or thioridazine hydrochloride, were prepared and characterized by elemental analysis and spectroscopic methods (FT-IR, UV-Vis, (1)H NMR and (13)C NMR). In addition, the crystal structure of the complex 2 containing trifluoroperazine dihydrochloride was solved by single crystal X-ray diffraction. The complex crystallizes in the monoclinic system, space group P2(1)/n, with a = 10.4935(7) angstrom, b = 18.6836(12) angstrom, c = 19.9250(13) angstrom, beta = 98.448(2)degrees, V = 3864.0(4) angstrom(3). The structure was refined to the agreement factors of R = 4.79%, R(w) = 11.23%. The effect of three different doses (0.4, 4.5 and 90.4 mu M/kg bw) of complex 2 on superoxide dismutase (SOD) and catalase (CAT) activity was investigated under physiological conditions. Influence on nitrite production (NO(2)(-)) and the level of erythrocytes malondialdehyde (MDA) in rats blood was also evaluated. Complex 2 did not affect the CAT enzyme activity in vivo and did not cause the hydroxyl radicals production. In the 0.4 and 4.5 mu M/kg bw doses it showed almost the same or lower SOD activity and nitrite levels, while the dose of 90.4 mu M/kg bw significantly increased these parameters. Finally, the cytotoxicity of complexes were assayed in four human carcinoma cell lines MCF-7, MDA-MB-453 (breast carcinoma), SW-480 (colon adenocarcinoma) and IM9 (myeloma multiple cells). Antiproliferative activity in vitro with low IC(50) during 48 h of treatment was observed. (C) 2010 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity",
volume = "45",
number = "9",
pages = "3669-3676",
doi = "10.1016/j.ejmech.2010.05.013"
}
Krstić, M., Sovilj, S. P., Grgurić-Šipka, S., Evans, I. R., Borozan, S., Santibanez, J. F.,& Kocic, J.. (2010). New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Paris., 45(9), 3669-3676.
https://doi.org/10.1016/j.ejmech.2010.05.013
Krstić M, Sovilj SP, Grgurić-Šipka S, Evans IR, Borozan S, Santibanez JF, Kocic J. New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity. in European Journal of Medicinal Chemistry. 2010;45(9):3669-3676.
doi:10.1016/j.ejmech.2010.05.013 .
Krstić, Milena, Sovilj, Sofija P., Grgurić-Šipka, Sanja, Evans, Ivana Radosavljevic, Borozan, Sunčica, Santibanez, Juan Francisco, Kocic, Jelena, "New ruthenium(II) complexes with N-alkylphenothiazines: Synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxicity" in European Journal of Medicinal Chemistry, 45, no. 9 (2010):3669-3676,
https://doi.org/10.1016/j.ejmech.2010.05.013 . .
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Different intermolecular interactions in azido[2-(diphenylphosphino)benzaldehyde semicarbazonato-kappa P-2,N-1,O]nickel(II)

Novaković, Sladjana B.; Bogdanović, Goran A.; Brčeski, Ilija; Leovac, Vukadin M.

(Wiley-Blackwell, Malden, 2009)

TY  - JOUR
AU  - Novaković, Sladjana B.
AU  - Bogdanović, Goran A.
AU  - Brčeski, Ilija
AU  - Leovac, Vukadin M.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1000
AB  - The title compound, [Ni(C20H17N3OP)(N-3)], is the first complex with a semicarbazide-based ligand having a P atom as one of the donors. The influence of the P atom on the deformation of the coordination geometry of the Ni-II ion is evident but less expressed than in the cases of complexes with analogous seleno-and thiosemicarbazide ligands. The torsion angles involving the two bonds formed by the P atom within the six-membered chelate ring have the largest values [C-P-Ni-N = 24.3 (2)degrees and C-C-P-Ni = -24.2 (4)degrees], suggesting that the P atom considerably influences the conformation of the ring. Two types of N-H center dot center dot center dot N hydrogen bond connect the complex units into chains.
PB  - Wiley-Blackwell, Malden
T2  - Acta Crystallographica. Section C: Crystal Structure Communications
T1  - Different intermolecular interactions in azido[2-(diphenylphosphino)benzaldehyde semicarbazonato-kappa P-2,N-1,O]nickel(II)
VL  - 65
DO  - 10.1107/S0108270109021970
ER  - 
@article{
author = "Novaković, Sladjana B. and Bogdanović, Goran A. and Brčeski, Ilija and Leovac, Vukadin M.",
year = "2009",
abstract = "The title compound, [Ni(C20H17N3OP)(N-3)], is the first complex with a semicarbazide-based ligand having a P atom as one of the donors. The influence of the P atom on the deformation of the coordination geometry of the Ni-II ion is evident but less expressed than in the cases of complexes with analogous seleno-and thiosemicarbazide ligands. The torsion angles involving the two bonds formed by the P atom within the six-membered chelate ring have the largest values [C-P-Ni-N = 24.3 (2)degrees and C-C-P-Ni = -24.2 (4)degrees], suggesting that the P atom considerably influences the conformation of the ring. Two types of N-H center dot center dot center dot N hydrogen bond connect the complex units into chains.",
publisher = "Wiley-Blackwell, Malden",
journal = "Acta Crystallographica. Section C: Crystal Structure Communications",
title = "Different intermolecular interactions in azido[2-(diphenylphosphino)benzaldehyde semicarbazonato-kappa P-2,N-1,O]nickel(II)",
volume = "65",
doi = "10.1107/S0108270109021970"
}
Novaković, S. B., Bogdanović, G. A., Brčeski, I.,& Leovac, V. M.. (2009). Different intermolecular interactions in azido[2-(diphenylphosphino)benzaldehyde semicarbazonato-kappa P-2,N-1,O]nickel(II). in Acta Crystallographica. Section C: Crystal Structure Communications
Wiley-Blackwell, Malden., 65.
https://doi.org/10.1107/S0108270109021970
Novaković SB, Bogdanović GA, Brčeski I, Leovac VM. Different intermolecular interactions in azido[2-(diphenylphosphino)benzaldehyde semicarbazonato-kappa P-2,N-1,O]nickel(II). in Acta Crystallographica. Section C: Crystal Structure Communications. 2009;65.
doi:10.1107/S0108270109021970 .
Novaković, Sladjana B., Bogdanović, Goran A., Brčeski, Ilija, Leovac, Vukadin M., "Different intermolecular interactions in azido[2-(diphenylphosphino)benzaldehyde semicarbazonato-kappa P-2,N-1,O]nickel(II)" in Acta Crystallographica. Section C: Crystal Structure Communications, 65 (2009),
https://doi.org/10.1107/S0108270109021970 . .
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A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives

Vuckovic, Gordana; Tanaskovic, Sladana B.; Antonijević-Nikolić, Mirjana; Živković-Radovanović, Vukosava; Gojgić-Cvijović, Gordana D.

(Serbian Chemical Soc, Belgrade, 2009)

TY  - JOUR
AU  - Vuckovic, Gordana
AU  - Tanaskovic, Sladana B.
AU  - Antonijević-Nikolić, Mirjana
AU  - Živković-Radovanović, Vukosava
AU  - Gojgić-Cvijović, Gordana D.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1003
AB  - Four new air-stable mixed-ligand Co(II) complexes having the general formula [Co(2)(Y)tpmc]Z(3)center dot q(H(2)O/CH(3)CN) (HY = N-methylglycine/N,N-dimethylglycine, Z = BF(4)(-), qH(2)O = 4 or 3; HY = S-norvaline/S-valine Z = ClO(4)(-), qCH(3)CN = 0.5; qH(2)O = 0.5; tpmc = N,N',N '',N'"-tetrakis(2-pyridymethyl)-1,4,8,11-tetraazacyclotetradecane) were prepared. The composition, some physical and chemical properties and their tentative geometries were evaluated based on elemental analysis (C, H, N), conductometric and magnetic measurernents, spectroscopic data (UV/Vis, IR) and cyclic voltammetry. The data were compared with earlier described analogous complexes containing the macrocyclic ligand and aliphatic aminocarboxylates. It is assumed that all complexes are binuclear with an exo coordination mode of the octaazarnacrocyclic pendant ligand in the boat conformation. In addition, two -N-(CH(2))(2)-N- portions of the cyclam ring within the tpmc ligand and Co(II) ions in the high-spin state are most probably bridged via oxygen atoms from the anion of the aminocarboxylate/derivatives, whereas nitrogen atoms rest uncoordinated. In all cases, a combined chelate-bridged coordination is proposed as the most probable. The complexes were electrochemically stable in the potential range -1.0 to 1.0 V. They were also preliminary assayed toward some microorganisms together with the ligands, starting simple salts and solvents as test substances. In some cases, certain antimicrobial activity of the complexes was detected.
AB  - Dobijena su četiri nova mešovito-ligandna kompleksa Co(II), stabilna na vazduhu, opšte formule [Co2(Y)tpmc]Z3×q(H2O/CH3CN) (HY = N-metilglicin/N,N-dimetilglicin, Z=-4BF , qH2O=4 ili 3); HY = S-norvalin/S-valin, Z=-ClO4, qCH3CN=0,5; qH2O=0,5; tpmc= N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11-tetraazaciklotetradekan). Sastav, neka fizička i hemijska svojstva i njihove približne geometrije su izvedene na osnovu elementalne analize (C, H, N), konduktometrijskih i magnetnih merenja, spektroskopskih podataka (UV/Vis, IR) odnosno ciklične voltametrije. Podaci su upoređeni sa ranije opisanim analogim kompleksima koji sadrže makrociklični ligand i alifatične aminokarboksilate. Pretpostavljeno je da su svi kompleksi dinuklearni sa egzo koordinacijom pendantnog oktaazamakrocikla u konformaciji lađe. Pored dva -N-(CH2)2-N- dela ciklamovog prstena unutar tpmc-a, joni visoko-spinskog Co(II) su najverovatnije premošćeni angažovanjem kiseonikovih atoma sa anjona aminokarboksilata/derivata, dok atomi azota ostaju nekoordinovani. Za sve komplekse predložen je kombinovani helatno-mostovni način vezivanja. Kompleksi su bili elektrohemijski stabilni u opsegu potencijala -1,0 do 1,0 V. Oni su preliminarno testirani na mikroorganizme zajedno sa ligandima, polaznim prostim solima i rastvaračima kao test supstancama. U nekim slučajevima je nađena izvesna antimikrobna aktivnost kompleksa.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives
T1  - Proučavanje novih kompleksa kobalta(II) sa oktaazamakrociklom i aminokarboksilatima ili njihovim derivatima
VL  - 74
IS  - 6
SP  - 629
EP  - 640
DO  - 10.2298/JSC0906629V
ER  - 
@article{
author = "Vuckovic, Gordana and Tanaskovic, Sladana B. and Antonijević-Nikolić, Mirjana and Živković-Radovanović, Vukosava and Gojgić-Cvijović, Gordana D.",
year = "2009",
abstract = "Four new air-stable mixed-ligand Co(II) complexes having the general formula [Co(2)(Y)tpmc]Z(3)center dot q(H(2)O/CH(3)CN) (HY = N-methylglycine/N,N-dimethylglycine, Z = BF(4)(-), qH(2)O = 4 or 3; HY = S-norvaline/S-valine Z = ClO(4)(-), qCH(3)CN = 0.5; qH(2)O = 0.5; tpmc = N,N',N '',N'"-tetrakis(2-pyridymethyl)-1,4,8,11-tetraazacyclotetradecane) were prepared. The composition, some physical and chemical properties and their tentative geometries were evaluated based on elemental analysis (C, H, N), conductometric and magnetic measurernents, spectroscopic data (UV/Vis, IR) and cyclic voltammetry. The data were compared with earlier described analogous complexes containing the macrocyclic ligand and aliphatic aminocarboxylates. It is assumed that all complexes are binuclear with an exo coordination mode of the octaazarnacrocyclic pendant ligand in the boat conformation. In addition, two -N-(CH(2))(2)-N- portions of the cyclam ring within the tpmc ligand and Co(II) ions in the high-spin state are most probably bridged via oxygen atoms from the anion of the aminocarboxylate/derivatives, whereas nitrogen atoms rest uncoordinated. In all cases, a combined chelate-bridged coordination is proposed as the most probable. The complexes were electrochemically stable in the potential range -1.0 to 1.0 V. They were also preliminary assayed toward some microorganisms together with the ligands, starting simple salts and solvents as test substances. In some cases, certain antimicrobial activity of the complexes was detected., Dobijena su četiri nova mešovito-ligandna kompleksa Co(II), stabilna na vazduhu, opšte formule [Co2(Y)tpmc]Z3×q(H2O/CH3CN) (HY = N-metilglicin/N,N-dimetilglicin, Z=-4BF , qH2O=4 ili 3); HY = S-norvalin/S-valin, Z=-ClO4, qCH3CN=0,5; qH2O=0,5; tpmc= N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11-tetraazaciklotetradekan). Sastav, neka fizička i hemijska svojstva i njihove približne geometrije su izvedene na osnovu elementalne analize (C, H, N), konduktometrijskih i magnetnih merenja, spektroskopskih podataka (UV/Vis, IR) odnosno ciklične voltametrije. Podaci su upoređeni sa ranije opisanim analogim kompleksima koji sadrže makrociklični ligand i alifatične aminokarboksilate. Pretpostavljeno je da su svi kompleksi dinuklearni sa egzo koordinacijom pendantnog oktaazamakrocikla u konformaciji lađe. Pored dva -N-(CH2)2-N- dela ciklamovog prstena unutar tpmc-a, joni visoko-spinskog Co(II) su najverovatnije premošćeni angažovanjem kiseonikovih atoma sa anjona aminokarboksilata/derivata, dok atomi azota ostaju nekoordinovani. Za sve komplekse predložen je kombinovani helatno-mostovni način vezivanja. Kompleksi su bili elektrohemijski stabilni u opsegu potencijala -1,0 do 1,0 V. Oni su preliminarno testirani na mikroorganizme zajedno sa ligandima, polaznim prostim solima i rastvaračima kao test supstancama. U nekim slučajevima je nađena izvesna antimikrobna aktivnost kompleksa.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives, Proučavanje novih kompleksa kobalta(II) sa oktaazamakrociklom i aminokarboksilatima ili njihovim derivatima",
volume = "74",
number = "6",
pages = "629-640",
doi = "10.2298/JSC0906629V"
}
Vuckovic, G., Tanaskovic, S. B., Antonijević-Nikolić, M., Živković-Radovanović, V.,& Gojgić-Cvijović, G. D.. (2009). A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 74(6), 629-640.
https://doi.org/10.2298/JSC0906629V
Vuckovic G, Tanaskovic SB, Antonijević-Nikolić M, Živković-Radovanović V, Gojgić-Cvijović GD. A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives. in Journal of the Serbian Chemical Society. 2009;74(6):629-640.
doi:10.2298/JSC0906629V .
Vuckovic, Gordana, Tanaskovic, Sladana B., Antonijević-Nikolić, Mirjana, Živković-Radovanović, Vukosava, Gojgić-Cvijović, Gordana D., "A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives" in Journal of the Serbian Chemical Society, 74, no. 6 (2009):629-640,
https://doi.org/10.2298/JSC0906629V . .
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Synthesis, characterization and antitumor activity of novel N-substituted alpha-amino acids containing ferrocenyl pyrazole-moiety

Joksović, Milan D.; Marković, Violeta; Juranić, Zorica D.; Stanojković, Tatjana; Jovanović, Ljiljana S.; Damljanovic, Ivan S.; Szecsenyi, Katalin Meszaros; Todorović, Nina; Trifunović, Snežana S.; Vukicevic, Rastko D.

(Elsevier Science Sa, Lausanne, 2009)

TY  - JOUR
AU  - Joksović, Milan D.
AU  - Marković, Violeta
AU  - Juranić, Zorica D.
AU  - Stanojković, Tatjana
AU  - Jovanović, Ljiljana S.
AU  - Damljanovic, Ivan S.
AU  - Szecsenyi, Katalin Meszaros
AU  - Todorović, Nina
AU  - Trifunović, Snežana S.
AU  - Vukicevic, Rastko D.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1024
AB  - A series of new N-[(3-ferrocenyl-1-phenylpyrazol-4-yl)methyl] alpha-amino acids were prepared and characterized by a range of spectroscopic techniques and cyclic voltammetry. The in vitro antitumor activity of all synthesized compounds was investigated against cervix adenocarcinoma HeLa, melanoma Fem-x and myelogenous leukemia K562 cell lines using the MTT method. Tryptophan derivative 11 exhibited the highest cytotoxic activity in the cell growth inhibition of all three types of cell lines. (C) 2009 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Sa, Lausanne
T2  - Journal of Organometallic Chemistry
T1  - Synthesis, characterization and antitumor activity of novel N-substituted alpha-amino acids containing ferrocenyl pyrazole-moiety
VL  - 694
IS  - 24
SP  - 3935
EP  - 3942
DO  - 10.1016/j.jorganchem.2009.08.013
ER  - 
@article{
author = "Joksović, Milan D. and Marković, Violeta and Juranić, Zorica D. and Stanojković, Tatjana and Jovanović, Ljiljana S. and Damljanovic, Ivan S. and Szecsenyi, Katalin Meszaros and Todorović, Nina and Trifunović, Snežana S. and Vukicevic, Rastko D.",
year = "2009",
abstract = "A series of new N-[(3-ferrocenyl-1-phenylpyrazol-4-yl)methyl] alpha-amino acids were prepared and characterized by a range of spectroscopic techniques and cyclic voltammetry. The in vitro antitumor activity of all synthesized compounds was investigated against cervix adenocarcinoma HeLa, melanoma Fem-x and myelogenous leukemia K562 cell lines using the MTT method. Tryptophan derivative 11 exhibited the highest cytotoxic activity in the cell growth inhibition of all three types of cell lines. (C) 2009 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Journal of Organometallic Chemistry",
title = "Synthesis, characterization and antitumor activity of novel N-substituted alpha-amino acids containing ferrocenyl pyrazole-moiety",
volume = "694",
number = "24",
pages = "3935-3942",
doi = "10.1016/j.jorganchem.2009.08.013"
}
Joksović, M. D., Marković, V., Juranić, Z. D., Stanojković, T., Jovanović, L. S., Damljanovic, I. S., Szecsenyi, K. M., Todorović, N., Trifunović, S. S.,& Vukicevic, R. D.. (2009). Synthesis, characterization and antitumor activity of novel N-substituted alpha-amino acids containing ferrocenyl pyrazole-moiety. in Journal of Organometallic Chemistry
Elsevier Science Sa, Lausanne., 694(24), 3935-3942.
https://doi.org/10.1016/j.jorganchem.2009.08.013
Joksović MD, Marković V, Juranić ZD, Stanojković T, Jovanović LS, Damljanovic IS, Szecsenyi KM, Todorović N, Trifunović SS, Vukicevic RD. Synthesis, characterization and antitumor activity of novel N-substituted alpha-amino acids containing ferrocenyl pyrazole-moiety. in Journal of Organometallic Chemistry. 2009;694(24):3935-3942.
doi:10.1016/j.jorganchem.2009.08.013 .
Joksović, Milan D., Marković, Violeta, Juranić, Zorica D., Stanojković, Tatjana, Jovanović, Ljiljana S., Damljanovic, Ivan S., Szecsenyi, Katalin Meszaros, Todorović, Nina, Trifunović, Snežana S., Vukicevic, Rastko D., "Synthesis, characterization and antitumor activity of novel N-substituted alpha-amino acids containing ferrocenyl pyrazole-moiety" in Journal of Organometallic Chemistry, 694, no. 24 (2009):3935-3942,
https://doi.org/10.1016/j.jorganchem.2009.08.013 . .
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Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel

Živković-Radovanović, Vukosava; Vuckovic, Gordana

(Vieweg, Wiesbaden, 2008)

TY  - JOUR
AU  - Živković-Radovanović, Vukosava
AU  - Vuckovic, Gordana
PY  - 2008
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/911
AB  - Saturated aqueous solutions of 28 different salts have been studied as a potential mobile phases for salting-out thin-layer chromatography, on silica gel, of a series of four mixed bis-aminocarboxylato cobalt(III) complexes. In addition, by linear regression analysis of chromatographic data obtained for fifteen mixed aminocarboxylato Co(III) complexes (four series) with solutions of ammonium chloride, three alkali metal chlorides, and four alkaline earth metal chlorides, four linear dependences previously established on different adsorbents with (NH4)(2)SO4 solutions were confirmed. The qualities of the separations achieved with the salts were compared and Li+, Mg2+, and Ca2+ chlorides are proposed as the most suitable.
PB  - Vieweg, Wiesbaden
T2  - Chromatographia
T1  - Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel
VL  - 67
IS  - 3-4
SP  - 259
EP  - 267
DO  - 10.1365/s10337-007-0489-y
ER  - 
@article{
author = "Živković-Radovanović, Vukosava and Vuckovic, Gordana",
year = "2008",
abstract = "Saturated aqueous solutions of 28 different salts have been studied as a potential mobile phases for salting-out thin-layer chromatography, on silica gel, of a series of four mixed bis-aminocarboxylato cobalt(III) complexes. In addition, by linear regression analysis of chromatographic data obtained for fifteen mixed aminocarboxylato Co(III) complexes (four series) with solutions of ammonium chloride, three alkali metal chlorides, and four alkaline earth metal chlorides, four linear dependences previously established on different adsorbents with (NH4)(2)SO4 solutions were confirmed. The qualities of the separations achieved with the salts were compared and Li+, Mg2+, and Ca2+ chlorides are proposed as the most suitable.",
publisher = "Vieweg, Wiesbaden",
journal = "Chromatographia",
title = "Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel",
volume = "67",
number = "3-4",
pages = "259-267",
doi = "10.1365/s10337-007-0489-y"
}
Živković-Radovanović, V.,& Vuckovic, G.. (2008). Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel. in Chromatographia
Vieweg, Wiesbaden., 67(3-4), 259-267.
https://doi.org/10.1365/s10337-007-0489-y
Živković-Radovanović V, Vuckovic G. Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel. in Chromatographia. 2008;67(3-4):259-267.
doi:10.1365/s10337-007-0489-y .
Živković-Radovanović, Vukosava, Vuckovic, Gordana, "Use of different salt solutions in salting-out TLC of Co(III) complexes on silica gel" in Chromatographia, 67, no. 3-4 (2008):259-267,
https://doi.org/10.1365/s10337-007-0489-y . .
8
7
8
8

Comparison of structural features of three new cis-dioxomolybdenum(VI) complexes with 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone: Possible role of intermolecular interactions on the geometry of the cis-MoO(2) unit

Tomić, Zoran D.; Kapor, Agnes; Zmiric, Aleksandra; Leovac, Vukadin M.; Zobel, Dieter; Zarić, Snežana D.

(Elsevier Science Sa, Lausanne, 2007)

TY  - JOUR
AU  - Tomić, Zoran D.
AU  - Kapor, Agnes
AU  - Zmiric, Aleksandra
AU  - Leovac, Vukadin M.
AU  - Zobel, Dieter
AU  - Zarić, Snežana D.
PY  - 2007
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/830
AB  - Three closely related [MoO(2)(L)(ML)] complexes, where L is the 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone ligand, and ML is EtOH (I), Py (II) and DMSO (III), were synthesized, characterized by NMR and IR spectra, and their X-ray crystal structures were determined. The crystal structure properties of these three closely related complexes were compared. Two cis-Mo-O bond lengths were almost the same in the crystal structure of complexes II and III, while in complex I a significant difference between the two cis-Mo-O bond lengths was observed. At the same time, the geometry of L ligand in complex I is different, compared to II and III. DFT calculations on the isolated molecule I, as well as geometrical analysis of the complexes indicate that intramolecular interactions are not responsible for these structural differences. On the other hand, the pattern of intermolecular contacts in the crystal structure of I differs from those observed in II and III. Analyses indicate that differences in cis-Mo-O bond lengths and in the geometry of ligand L could be related to intermolecular interactions. These results suggest the possibility that in enzymes oxotransferases or in their model systems, the Mo-O bond length could be designed by the interactions of chelate ligands with the surroundings. (C) 2006 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Sa, Lausanne
T2  - Inorganica Chimica Acta
T1  - Comparison of structural features of three new cis-dioxomolybdenum(VI) complexes with 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone: Possible role of intermolecular interactions on the geometry of the cis-MoO(2) unit
VL  - 360
IS  - 7
SP  - 2197
EP  - 2206
DO  - 10.1016/j.ica.2006.10.026
ER  - 
@article{
author = "Tomić, Zoran D. and Kapor, Agnes and Zmiric, Aleksandra and Leovac, Vukadin M. and Zobel, Dieter and Zarić, Snežana D.",
year = "2007",
abstract = "Three closely related [MoO(2)(L)(ML)] complexes, where L is the 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone ligand, and ML is EtOH (I), Py (II) and DMSO (III), were synthesized, characterized by NMR and IR spectra, and their X-ray crystal structures were determined. The crystal structure properties of these three closely related complexes were compared. Two cis-Mo-O bond lengths were almost the same in the crystal structure of complexes II and III, while in complex I a significant difference between the two cis-Mo-O bond lengths was observed. At the same time, the geometry of L ligand in complex I is different, compared to II and III. DFT calculations on the isolated molecule I, as well as geometrical analysis of the complexes indicate that intramolecular interactions are not responsible for these structural differences. On the other hand, the pattern of intermolecular contacts in the crystal structure of I differs from those observed in II and III. Analyses indicate that differences in cis-Mo-O bond lengths and in the geometry of ligand L could be related to intermolecular interactions. These results suggest the possibility that in enzymes oxotransferases or in their model systems, the Mo-O bond length could be designed by the interactions of chelate ligands with the surroundings. (C) 2006 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Inorganica Chimica Acta",
title = "Comparison of structural features of three new cis-dioxomolybdenum(VI) complexes with 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone: Possible role of intermolecular interactions on the geometry of the cis-MoO(2) unit",
volume = "360",
number = "7",
pages = "2197-2206",
doi = "10.1016/j.ica.2006.10.026"
}
Tomić, Z. D., Kapor, A., Zmiric, A., Leovac, V. M., Zobel, D.,& Zarić, S. D.. (2007). Comparison of structural features of three new cis-dioxomolybdenum(VI) complexes with 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone: Possible role of intermolecular interactions on the geometry of the cis-MoO(2) unit. in Inorganica Chimica Acta
Elsevier Science Sa, Lausanne., 360(7), 2197-2206.
https://doi.org/10.1016/j.ica.2006.10.026
Tomić ZD, Kapor A, Zmiric A, Leovac VM, Zobel D, Zarić SD. Comparison of structural features of three new cis-dioxomolybdenum(VI) complexes with 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone: Possible role of intermolecular interactions on the geometry of the cis-MoO(2) unit. in Inorganica Chimica Acta. 2007;360(7):2197-2206.
doi:10.1016/j.ica.2006.10.026 .
Tomić, Zoran D., Kapor, Agnes, Zmiric, Aleksandra, Leovac, Vukadin M., Zobel, Dieter, Zarić, Snežana D., "Comparison of structural features of three new cis-dioxomolybdenum(VI) complexes with 2-hydroxy-1-naphthaldehyde-S-methylisothiosemicarbazone: Possible role of intermolecular interactions on the geometry of the cis-MoO(2) unit" in Inorganica Chimica Acta, 360, no. 7 (2007):2197-2206,
https://doi.org/10.1016/j.ica.2006.10.026 . .
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