TY  - THES
AU  - Rakić, Gordana M.
PY  - 2017
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=5596
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:17104/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49836559
UR  - http://nardus.mpn.gov.rs/123456789/9176
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2747
AB  - U ovoj doktorskoj disertaciji opisana je sinteza, karakterizacija i antitumorskaaktivnost šest kompleksa trans-platine(II) i pet kompleksa trans-platine(IV) sapiridinskim derivatima kao ligandima. Sintetisani kompleksi dobijeni su reakcijompolaznih kompleksa platine, K2[PtCl4] odnosno K2[PtCl6], sa odgovarajućim ligandimau molskom odnosu 1 : 2 u vodi, uz blago zagrevanje. Za sintezu kompleksa korišćeni sukomercijalno dostupni ligandi koji predstavljaju piridinske derivate sa acetilsupstituentima (3- i 4-acetilpiridin) i sa dve karboksilne grupe (2,3-, 2,4-, 2,5- i2,6-piridindikarboksilna kiselina)...
AB  - In this doctoral dissertation, synthesis, characterization and antitumour activityof six trans-platinum(II) and five trans-platinum(IV) complexes with pyridinederivatives as ligands were described. The complexes were synthesized in the reactionof starting compounds of platinum K2[PtCl4] and K2[PtCl6], with the correspondingligand in a 1 : 2 molar ratio in water, with mild heating. Commercially available ligandsused for preparation of complexes could be considered as pyridine derivatives withacetyl substituted (3- and 4-acetylpyridine) and with two carboxylic groups (2,3-, 2,4-,2,5- i 2,6-pyridinedicarboxylic acid)...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Sinteza, karakterizacija i antitumorska aktivnost trans-kompleksa Pt(II) i Pt(IV) sa piridinskim derivatima kao ligandima
UR  - https://hdl.handle.net/21.15107/rcub_nardus_9176
ER  - 

@phdthesis{
author = "Rakić, Gordana M.",
year = "2017",
abstract = "U ovoj doktorskoj disertaciji opisana je sinteza, karakterizacija i antitumorskaaktivnost šest kompleksa trans-platine(II) i pet kompleksa trans-platine(IV) sapiridinskim derivatima kao ligandima. Sintetisani kompleksi dobijeni su reakcijompolaznih kompleksa platine, K2[PtCl4] odnosno K2[PtCl6], sa odgovarajućim ligandimau molskom odnosu 1 : 2 u vodi, uz blago zagrevanje. Za sintezu kompleksa korišćeni sukomercijalno dostupni ligandi koji predstavljaju piridinske derivate sa acetilsupstituentima (3- i 4-acetilpiridin) i sa dve karboksilne grupe (2,3-, 2,4-, 2,5- i2,6-piridindikarboksilna kiselina)..., In this doctoral dissertation, synthesis, characterization and antitumour activityof six trans-platinum(II) and five trans-platinum(IV) complexes with pyridinederivatives as ligands were described. The complexes were synthesized in the reactionof starting compounds of platinum K2[PtCl4] and K2[PtCl6], with the correspondingligand in a 1 : 2 molar ratio in water, with mild heating. Commercially available ligandsused for preparation of complexes could be considered as pyridine derivatives withacetyl substituted (3- and 4-acetylpyridine) and with two carboxylic groups (2,3-, 2,4-,2,5- i 2,6-pyridinedicarboxylic acid)...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Sinteza, karakterizacija i antitumorska aktivnost trans-kompleksa Pt(II) i Pt(IV) sa piridinskim derivatima kao ligandima",
url = "https://hdl.handle.net/21.15107/rcub_nardus_9176"
}

Rakić, G. M.. (2017). Sinteza, karakterizacija i antitumorska aktivnost trans-kompleksa Pt(II) i Pt(IV) sa piridinskim derivatima kao ligandima. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_9176

Rakić GM. Sinteza, karakterizacija i antitumorska aktivnost trans-kompleksa Pt(II) i Pt(IV) sa piridinskim derivatima kao ligandima. in Универзитет у Београду. 2017;.
https://hdl.handle.net/21.15107/rcub_nardus_9176 .

Rakić, Gordana M., "Sinteza, karakterizacija i antitumorska aktivnost trans-kompleksa Pt(II) i Pt(IV) sa piridinskim derivatima kao ligandima" in Универзитет у Београду (2017),
https://hdl.handle.net/21.15107/rcub_nardus_9176 .

TY  - THES
AU  - Andrić, Filip
PY  - 2014
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=3262
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:11665/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=45318927
UR  - http://nardus.mpn.gov.rs/123456789/5903
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2688
AB  - Cilj ove disertacije bio je razvoj metoda tankoslojne hromatografije zaodređivanje podeonih koeficijenata, pre svega oktanol-voda (logKOW), zemljište-voda(logKOC), vazduh-voda (logKAW) i solvatohromnih (A, B i S) parametara malihorganskih molekula na osnovu kojih se, primenom pristupa lineranih odnosa energijesolvatacije (LSER), mogu dalje proceniti: stepen aporpcije u gastrointestinalnom traktu(% Abs), raspodela u sistemu krv-koža (logPskin), voda-koža (logKP, logKSC) i krvmoždana-barijera(log BBB).Za određivanje datih parametara izvorne metode su vremenski zahtevne,podrazumevaju veliku količinu analita i imaju ograničeni radni opseg. Zbog toga su uvelikoj meri zamenjene različitim hromatografskim tehnikama, pre svega visokoefikasnomtečnom hromatografijom (HPLC). Međutim, tankoslojna hromatografija imaniz prednosti nad HPLC metodom. To je jednostavna, brza, jeftina metoda, koja koristimale količine analita i reagenasa. Do sada nije sistematski ispitivana njena primena uodređivanju pomenutih parametara.U okviru ove disertacije primenjeni su različiti reverezno-fazni i normalno-faznihromatografski sistemi na skupu od 70 organskih jedinjenja malih molekulskih masa, ukombinaciji sa različitim kalibracionim tehnikama: univarijantna regresija (OLS),regresija glavnih komponenata (PCR), regresija metodom delimičnih najmanjihkvadrata (PLS). Pri tome je izvršena selekcija hromatografskih sistema i definisanjeradnih opsega za svaki od proučavanih pariticionih koeficijenata te, tipova organskihjedinjenja na koja se dati izbor hromatografskih uslova može primeniti. Razvijenipostupci su okarakterisani parametrima preciznosti, tačnosti, prediktivne moći i ostalimparametarima validacije modela
AB  - The aim of this thesis was the development of thin-layer chromatographicmethods for the determination of partition coefficients, primarily octanol-water(logKow), soil-water (logKOC), air-to-water (logKAW ) and Abraham’s solvatochromicparameters of small organic molecules which can be further used to estimate: thegastrointestinal tract absorption (%Abs), the blood to skin distribution (logPskin), water- skin (logKP, logKsc) and the blood to brain partition (logBBB).Original methods used to determine the aforementioned parameters are timeconsuming, involve a large amount of the analyte and have limited working range.Therefore, they are, to a large extent, replaced by various chromatographic techniques,especially high-performance liquid chromatography. However, thin-layerchromatography has a number of advantages over HPLC method. It is simple, fast,inexpensive method that uses small amounts of analytes and reagents. So far itsapplication in the determination of the parameters mentioned above has not beensystematically studied.In the scope of this dissertation, several reversed-phase and normal-phasechromatographic systems were applied on a set of 70 organic compounds of lowmolecular weight in order to determine the partitioning as well as solvatochromicparameters, in combination with a variety of calibration methods: univariate regression(OLS), principal component regression (PCR), partial least squares regression (PLS).For each of the studied pratitioning coefficients careful selection and definition ofchromatographic systems, operating conditions, working ranges and the types of organiccompounds on which the developed method could be applied have been done.The developed methods were fruther characterized by the parameters ofprecision, accuracy, predictive power, and other parameters of the model validation
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Određivanje podeonih koeficijenata i solvatohromnih parametara malih organskih molekula primenom tankoslojne hromatografije i hemometrije
T1  - Determination of partition coefficients and solvatochromic parameters of small organic molecules by thin-layer chromatography and chemometrics
UR  - https://hdl.handle.net/21.15107/rcub_nardus_5903
ER  - 

@phdthesis{
author = "Andrić, Filip",
year = "2014",
abstract = "Cilj ove disertacije bio je razvoj metoda tankoslojne hromatografije zaodređivanje podeonih koeficijenata, pre svega oktanol-voda (logKOW), zemljište-voda(logKOC), vazduh-voda (logKAW) i solvatohromnih (A, B i S) parametara malihorganskih molekula na osnovu kojih se, primenom pristupa lineranih odnosa energijesolvatacije (LSER), mogu dalje proceniti: stepen aporpcije u gastrointestinalnom traktu(% Abs), raspodela u sistemu krv-koža (logPskin), voda-koža (logKP, logKSC) i krvmoždana-barijera(log BBB).Za određivanje datih parametara izvorne metode su vremenski zahtevne,podrazumevaju veliku količinu analita i imaju ograničeni radni opseg. Zbog toga su uvelikoj meri zamenjene različitim hromatografskim tehnikama, pre svega visokoefikasnomtečnom hromatografijom (HPLC). Međutim, tankoslojna hromatografija imaniz prednosti nad HPLC metodom. To je jednostavna, brza, jeftina metoda, koja koristimale količine analita i reagenasa. Do sada nije sistematski ispitivana njena primena uodređivanju pomenutih parametara.U okviru ove disertacije primenjeni su različiti reverezno-fazni i normalno-faznihromatografski sistemi na skupu od 70 organskih jedinjenja malih molekulskih masa, ukombinaciji sa različitim kalibracionim tehnikama: univarijantna regresija (OLS),regresija glavnih komponenata (PCR), regresija metodom delimičnih najmanjihkvadrata (PLS). Pri tome je izvršena selekcija hromatografskih sistema i definisanjeradnih opsega za svaki od proučavanih pariticionih koeficijenata te, tipova organskihjedinjenja na koja se dati izbor hromatografskih uslova može primeniti. Razvijenipostupci su okarakterisani parametrima preciznosti, tačnosti, prediktivne moći i ostalimparametarima validacije modela, The aim of this thesis was the development of thin-layer chromatographicmethods for the determination of partition coefficients, primarily octanol-water(logKow), soil-water (logKOC), air-to-water (logKAW ) and Abraham’s solvatochromicparameters of small organic molecules which can be further used to estimate: thegastrointestinal tract absorption (%Abs), the blood to skin distribution (logPskin), water- skin (logKP, logKsc) and the blood to brain partition (logBBB).Original methods used to determine the aforementioned parameters are timeconsuming, involve a large amount of the analyte and have limited working range.Therefore, they are, to a large extent, replaced by various chromatographic techniques,especially high-performance liquid chromatography. However, thin-layerchromatography has a number of advantages over HPLC method. It is simple, fast,inexpensive method that uses small amounts of analytes and reagents. So far itsapplication in the determination of the parameters mentioned above has not beensystematically studied.In the scope of this dissertation, several reversed-phase and normal-phasechromatographic systems were applied on a set of 70 organic compounds of lowmolecular weight in order to determine the partitioning as well as solvatochromicparameters, in combination with a variety of calibration methods: univariate regression(OLS), principal component regression (PCR), partial least squares regression (PLS).For each of the studied pratitioning coefficients careful selection and definition ofchromatographic systems, operating conditions, working ranges and the types of organiccompounds on which the developed method could be applied have been done.The developed methods were fruther characterized by the parameters ofprecision, accuracy, predictive power, and other parameters of the model validation",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Određivanje podeonih koeficijenata i solvatohromnih parametara malih organskih molekula primenom tankoslojne hromatografije i hemometrije, Determination of partition coefficients and solvatochromic parameters of small organic molecules by thin-layer chromatography and chemometrics",
url = "https://hdl.handle.net/21.15107/rcub_nardus_5903"
}

Andrić, F.. (2014). Određivanje podeonih koeficijenata i solvatohromnih parametara malih organskih molekula primenom tankoslojne hromatografije i hemometrije. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_5903

Andrić F. Određivanje podeonih koeficijenata i solvatohromnih parametara malih organskih molekula primenom tankoslojne hromatografije i hemometrije. in Универзитет у Београду. 2014;.
https://hdl.handle.net/21.15107/rcub_nardus_5903 .

Andrić, Filip, "Određivanje podeonih koeficijenata i solvatohromnih parametara malih organskih molekula primenom tankoslojne hromatografije i hemometrije" in Универзитет у Београду (2014),
https://hdl.handle.net/21.15107/rcub_nardus_5903 .

TY  - JOUR
AU  - Dabić Zagorac, Dragana
AU  - Natić, Maja
AU  - Džambaski, Zdravko
AU  - Stojanović, Milovan
AU  - Marković, Rade
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav Lj.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1346
AB  - The chromatographic behavior of 23 new 2-alkylidene-4-oxothiazolidine derivatives was investigated by means of the reversed-phase thin-layer chromatography (RP TLC) on the C18 and CN stationary phases. Binary mixtures of methanol-water, acetonitrile-water, and tetrahydrofuran-water were used as mobile phases. Linear relationships between the volume fraction of the organic mobile phase modifier and the RM values were established for each solute with high correlation coefficient values (r0.99). The investigated 4-oxothiazolidines are a congeneric set of compounds, and significant correlations were obtained between the chromatographically determined [image omitted] and m values. The lipophilicity parameters obtained from the reversed-phase experiments were compared with the calculated log P values. Some of these correlations offer very good predicting models, which are important for a better understanding of the relationships between chemical structure and retention, and can prove helpful in the structure-activity studies as well. Finally, our investigation was focused on chemometric processing of the retention data in different chromatographic systems. To this effect, Principal Component Analysis (PCA) was performed, yielding the results helpful in interpretation of interactions among investigated substances, binary mobile phases, and the two different stationary phases.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography and Related Technologies
T1  - Estimation of Lipophilicity of N-Substituted 2-Alkylidene-4-Oxothiazolidines by Means of Reversed-Phase Thin-Layer Chromatography
VL  - 34
IS  - 10-11
SP  - 791
EP  - 804
DO  - 10.1080/10826076.2011.571157
ER  - 

@article{
author = "Dabić Zagorac, Dragana and Natić, Maja and Džambaski, Zdravko and Stojanović, Milovan and Marković, Rade and Milojković-Opsenica, Dušanka and Tešić, Živoslav Lj.",
year = "2011",
abstract = "The chromatographic behavior of 23 new 2-alkylidene-4-oxothiazolidine derivatives was investigated by means of the reversed-phase thin-layer chromatography (RP TLC) on the C18 and CN stationary phases. Binary mixtures of methanol-water, acetonitrile-water, and tetrahydrofuran-water were used as mobile phases. Linear relationships between the volume fraction of the organic mobile phase modifier and the RM values were established for each solute with high correlation coefficient values (r0.99). The investigated 4-oxothiazolidines are a congeneric set of compounds, and significant correlations were obtained between the chromatographically determined [image omitted] and m values. The lipophilicity parameters obtained from the reversed-phase experiments were compared with the calculated log P values. Some of these correlations offer very good predicting models, which are important for a better understanding of the relationships between chemical structure and retention, and can prove helpful in the structure-activity studies as well. Finally, our investigation was focused on chemometric processing of the retention data in different chromatographic systems. To this effect, Principal Component Analysis (PCA) was performed, yielding the results helpful in interpretation of interactions among investigated substances, binary mobile phases, and the two different stationary phases.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography and Related Technologies",
title = "Estimation of Lipophilicity of N-Substituted 2-Alkylidene-4-Oxothiazolidines by Means of Reversed-Phase Thin-Layer Chromatography",
volume = "34",
number = "10-11",
pages = "791-804",
doi = "10.1080/10826076.2011.571157"
}

Dabić Zagorac, D., Natić, M., Džambaski, Z., Stojanović, M., Marković, R., Milojković-Opsenica, D.,& Tešić, Ž. Lj.. (2011). Estimation of Lipophilicity of N-Substituted 2-Alkylidene-4-Oxothiazolidines by Means of Reversed-Phase Thin-Layer Chromatography. in Journal of Liquid Chromatography and Related Technologies
Taylor & Francis Inc, Philadelphia., 34(10-11), 791-804.
https://doi.org/10.1080/10826076.2011.571157

Dabić Zagorac D, Natić M, Džambaski Z, Stojanović M, Marković R, Milojković-Opsenica D, Tešić ŽL. Estimation of Lipophilicity of N-Substituted 2-Alkylidene-4-Oxothiazolidines by Means of Reversed-Phase Thin-Layer Chromatography. in Journal of Liquid Chromatography and Related Technologies. 2011;34(10-11):791-804.
doi:10.1080/10826076.2011.571157 .

Dabić Zagorac, Dragana, Natić, Maja, Džambaski, Zdravko, Stojanović, Milovan, Marković, Rade, Milojković-Opsenica, Dušanka, Tešić, Živoslav Lj., "Estimation of Lipophilicity of N-Substituted 2-Alkylidene-4-Oxothiazolidines by Means of Reversed-Phase Thin-Layer Chromatography" in Journal of Liquid Chromatography and Related Technologies, 34, no. 10-11 (2011):791-804,
https://doi.org/10.1080/10826076.2011.571157 . .

TY  - JOUR
AU  - Ivanović, Ivanka
AU  - Grgurić-Šipka, Sanja
AU  - Gligorijević, Nevenka
AU  - Radulović, Siniša
AU  - Roller, Alexander
AU  - Tešić, Živoslav Lj.
AU  - Keppler, Bernhard K.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1149
AB  - A ruthenium(II)-arene complex with picolinic acid, [(eta(6)-p-cymene)RuCl(pico)]center dot H(2)O, was prepared by the reaction of [(eta(6)-p-cymene)RuCl(2)](2) with picolinic acid in a 1:2 molar ratio in 2-propanol. The compound was characterized by elemental analysis, and IR and NMR spectroscopy. X-ray diffraction analysis showed that the molecule adopts a "three-leg piano-stool" geometry, which is common for this type of complexes. The cytotoxic activity of the complex was tested in two human cancer cell lines HeLa (cervix) and FemX (melanoma) by MTT assay. The IC(50) values were at 82.0 and 36.2 mu mol dm(-3) for HeLa and FemX cells, respectively.
AB  - Rutenijum(II)-arenski kompleks sa pikolinskom kiselinom [(η6-p-cimen)RuCl(pikolinato)]·H2O sintetisan je u reakciji [(η6-p-cimen)RuCl2]2 kompleksa sa pikolinskom kiselinom u molskom odnosu 1:2 u izopropanolu. Jedinjenje je okarakterisano elementalnom analizom, IC i NMR spektroskopijom. Analiza difrakcijom X-zracima pokazala je da molekul ima tzv. 'three-leg piano-stool' geometriju koja je karakteristična za ovaj tip kompleksa. Citotoksična aktivnost kompleksa je određena na dve humane tumorske ćelijske linije, HeLa (grlića materice) i FemX (melanoma), MTT testom. IC50 vrednosti su bile 82,0 i 36,2 µmol dm-3 za HeLa i FemX ćelije, redom.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - X-Ray structure and cytotoxic activity of a picolinate ruthenium(II)-arene complex
T1  - Rendgenska strukturna analiza i citotoksična aktivnost pikolinato rutenijum(II)-arenskog kompleksa
VL  - 76
IS  - 1
SP  - 53
EP  - 61
DO  - 10.2298/JSC100517017I
ER  - 

@article{
author = "Ivanović, Ivanka and Grgurić-Šipka, Sanja and Gligorijević, Nevenka and Radulović, Siniša and Roller, Alexander and Tešić, Živoslav Lj. and Keppler, Bernhard K.",
year = "2011",
abstract = "A ruthenium(II)-arene complex with picolinic acid, [(eta(6)-p-cymene)RuCl(pico)]center dot H(2)O, was prepared by the reaction of [(eta(6)-p-cymene)RuCl(2)](2) with picolinic acid in a 1:2 molar ratio in 2-propanol. The compound was characterized by elemental analysis, and IR and NMR spectroscopy. X-ray diffraction analysis showed that the molecule adopts a "three-leg piano-stool" geometry, which is common for this type of complexes. The cytotoxic activity of the complex was tested in two human cancer cell lines HeLa (cervix) and FemX (melanoma) by MTT assay. The IC(50) values were at 82.0 and 36.2 mu mol dm(-3) for HeLa and FemX cells, respectively., Rutenijum(II)-arenski kompleks sa pikolinskom kiselinom [(η6-p-cimen)RuCl(pikolinato)]·H2O sintetisan je u reakciji [(η6-p-cimen)RuCl2]2 kompleksa sa pikolinskom kiselinom u molskom odnosu 1:2 u izopropanolu. Jedinjenje je okarakterisano elementalnom analizom, IC i NMR spektroskopijom. Analiza difrakcijom X-zracima pokazala je da molekul ima tzv. 'three-leg piano-stool' geometriju koja je karakteristična za ovaj tip kompleksa. Citotoksična aktivnost kompleksa je određena na dve humane tumorske ćelijske linije, HeLa (grlića materice) i FemX (melanoma), MTT testom. IC50 vrednosti su bile 82,0 i 36,2 µmol dm-3 za HeLa i FemX ćelije, redom.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "X-Ray structure and cytotoxic activity of a picolinate ruthenium(II)-arene complex, Rendgenska strukturna analiza i citotoksična aktivnost pikolinato rutenijum(II)-arenskog kompleksa",
volume = "76",
number = "1",
pages = "53-61",
doi = "10.2298/JSC100517017I"
}

Ivanović, I., Grgurić-Šipka, S., Gligorijević, N., Radulović, S., Roller, A., Tešić, Ž. Lj.,& Keppler, B. K.. (2011). X-Ray structure and cytotoxic activity of a picolinate ruthenium(II)-arene complex. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 76(1), 53-61.
https://doi.org/10.2298/JSC100517017I

Ivanović I, Grgurić-Šipka S, Gligorijević N, Radulović S, Roller A, Tešić ŽL, Keppler BK. X-Ray structure and cytotoxic activity of a picolinate ruthenium(II)-arene complex. in Journal of the Serbian Chemical Society. 2011;76(1):53-61.
doi:10.2298/JSC100517017I .

Ivanović, Ivanka, Grgurić-Šipka, Sanja, Gligorijević, Nevenka, Radulović, Siniša, Roller, Alexander, Tešić, Živoslav Lj., Keppler, Bernhard K., "X-Ray structure and cytotoxic activity of a picolinate ruthenium(II)-arene complex" in Journal of the Serbian Chemical Society, 76, no. 1 (2011):53-61,
https://doi.org/10.2298/JSC100517017I . .

TY  - JOUR
AU  - Ilic, Sanja
AU  - Natić, Maja
AU  - Dabić Zagorac, Dragana
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav Lj.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1336
AB  - Two-dimensional (2D) TLC of eleven phenols has been performed on octadecyl-silica. The most efficient systems were selected by analysis of retention data obtained by one-dimensional chromatography using aqueous and non-aqueous mobile phases. Correlation graphs were plotted to illustrate the separation in the chromatographic systems examined. Complete separation of the phenols was achieved by using an aqueous mobile phase in the first dimension and a non-aqueous mobile phase in the second dimension. Statistical methods (principal-components analysis and cluster analysis) were used for better characterization of the TLC systems.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - 2D TLC Separation of Phenols by Use of RP-18 Silica Plates with Aqueous and Non-Aqueous Mobile Phases
VL  - 24
IS  - 2
SP  - 93
EP  - 98
DO  - 10.1556/JPC.24.2011.2.1
ER  - 

@article{
author = "Ilic, Sanja and Natić, Maja and Dabić Zagorac, Dragana and Milojković-Opsenica, Dušanka and Tešić, Živoslav Lj.",
year = "2011",
abstract = "Two-dimensional (2D) TLC of eleven phenols has been performed on octadecyl-silica. The most efficient systems were selected by analysis of retention data obtained by one-dimensional chromatography using aqueous and non-aqueous mobile phases. Correlation graphs were plotted to illustrate the separation in the chromatographic systems examined. Complete separation of the phenols was achieved by using an aqueous mobile phase in the first dimension and a non-aqueous mobile phase in the second dimension. Statistical methods (principal-components analysis and cluster analysis) were used for better characterization of the TLC systems.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "2D TLC Separation of Phenols by Use of RP-18 Silica Plates with Aqueous and Non-Aqueous Mobile Phases",
volume = "24",
number = "2",
pages = "93-98",
doi = "10.1556/JPC.24.2011.2.1"
}

Ilic, S., Natić, M., Dabić Zagorac, D., Milojković-Opsenica, D.,& Tešić, Ž. Lj.. (2011). 2D TLC Separation of Phenols by Use of RP-18 Silica Plates with Aqueous and Non-Aqueous Mobile Phases. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Research Inst Medicinal Plants, Budakalasz., 24(2), 93-98.
https://doi.org/10.1556/JPC.24.2011.2.1

Ilic S, Natić M, Dabić Zagorac D, Milojković-Opsenica D, Tešić ŽL. 2D TLC Separation of Phenols by Use of RP-18 Silica Plates with Aqueous and Non-Aqueous Mobile Phases. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2011;24(2):93-98.
doi:10.1556/JPC.24.2011.2.1 .

Ilic, Sanja, Natić, Maja, Dabić Zagorac, Dragana, Milojković-Opsenica, Dušanka, Tešić, Živoslav Lj., "2D TLC Separation of Phenols by Use of RP-18 Silica Plates with Aqueous and Non-Aqueous Mobile Phases" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 24, no. 2 (2011):93-98,
https://doi.org/10.1556/JPC.24.2011.2.1 . .

TY  - JOUR
AU  - Sajewicz, Mieczyslaw
AU  - Staszek, Dorota
AU  - Natić, Maja
AU  - Waksmundzka-Hajnos, Monika
AU  - Kowalska, Teresa
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1180
PB  - Oxford Univ Press Inc, Cary
T2  - Journal of Chromatographic Science
T1  - TLC-MS Versus TLC-LC-MS Fingerprints of Herbal Extracts. Part III. Application of the Reversed-Phase liquid Chromatography Systems With C-18 Stationary Phase
VL  - 49
IS  - 7
SP  - 560
EP  - 567
DO  - 10.1093/chrsci/49.7.560
ER  - 

@article{
author = "Sajewicz, Mieczyslaw and Staszek, Dorota and Natić, Maja and Waksmundzka-Hajnos, Monika and Kowalska, Teresa",
year = "2011",
publisher = "Oxford Univ Press Inc, Cary",
journal = "Journal of Chromatographic Science",
title = "TLC-MS Versus TLC-LC-MS Fingerprints of Herbal Extracts. Part III. Application of the Reversed-Phase liquid Chromatography Systems With C-18 Stationary Phase",
volume = "49",
number = "7",
pages = "560-567",
doi = "10.1093/chrsci/49.7.560"
}

Sajewicz, M., Staszek, D., Natić, M., Waksmundzka-Hajnos, M.,& Kowalska, T.. (2011). TLC-MS Versus TLC-LC-MS Fingerprints of Herbal Extracts. Part III. Application of the Reversed-Phase liquid Chromatography Systems With C-18 Stationary Phase. in Journal of Chromatographic Science
Oxford Univ Press Inc, Cary., 49(7), 560-567.
https://doi.org/10.1093/chrsci/49.7.560

Sajewicz M, Staszek D, Natić M, Waksmundzka-Hajnos M, Kowalska T. TLC-MS Versus TLC-LC-MS Fingerprints of Herbal Extracts. Part III. Application of the Reversed-Phase liquid Chromatography Systems With C-18 Stationary Phase. in Journal of Chromatographic Science. 2011;49(7):560-567.
doi:10.1093/chrsci/49.7.560 .

Sajewicz, Mieczyslaw, Staszek, Dorota, Natić, Maja, Waksmundzka-Hajnos, Monika, Kowalska, Teresa, "TLC-MS Versus TLC-LC-MS Fingerprints of Herbal Extracts. Part III. Application of the Reversed-Phase liquid Chromatography Systems With C-18 Stationary Phase" in Journal of Chromatographic Science, 49, no. 7 (2011):560-567,
https://doi.org/10.1093/chrsci/49.7.560 . .

TY  - JOUR
AU  - Sajewicz, Mieczyslaw
AU  - Staszek, Dorota
AU  - Natić, Maja
AU  - Wojtal, Lukasz
AU  - Waksmundzka-Hajnos, Monika
AU  - Kowalska, Teresa
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1348
AB  - In the previous paper from this series, we proposed mass spectrometric fingerprinting of a complex and volatile botanical sample upon an example of the essential oil derived from Salvia lavandulifolia. In that paper, we compared two variants of fractionation of such a mixture. A simpler one-dimensional variant consisted of the low-temperature thin-layer chromatographic fractionation coupled with mass spectrometric fingerprinting of each separated fraction (1D LT TLC-MS). A more sophisticated variant was the two-dimensional liquid chromatographic system composed of the low-temperature thin-layer chromatography, high-performance liquid chromatography, and mass spectrometric detection (2D LT TLC-LC-MS). In this study, we present an analogous approach to the non-volatile botanical mixtures upon an example of the pharmacologically important phenolic acids and flavonoids selectively extracted from Salvia lavandulifolia. With these non-volatile fractions, the thin-layer chromatographic separations were carried out at ambient temperature (21 +/- 0.5 degrees C). Once again, we compared two variants of fractionation. A simpler one-dimensional variant consisted of the thin-layer chromatographic mode coupled with mass spectrometric fingerprinting of each separated fraction (1D TLC-MS). A more sophisticated variant was the two-dimensional liquid chromatographic system composed of the thin-layer chromatography and high-performance liquid chromatography, with mass spectrometric detection (2D TLC-LC-MS). As expected, the two-dimensional mode proved better performing than the one-dimensional mode (1D TLC-MS). It was concluded that thin-layer chromatography directly or indirectly coupled with mass spectrometric detection can prove very useful in the analysis of the phenolic acid and flavonoid fraction selectively extracted from botanical material.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography and Related Technologies
T1  - Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part Ii. Phenolic Acids and Flavonoids
VL  - 34
IS  - 10-11
SP  - 864
EP  - 887
DO  - 10.1080/10826076.2011.571131
ER  - 

@article{
author = "Sajewicz, Mieczyslaw and Staszek, Dorota and Natić, Maja and Wojtal, Lukasz and Waksmundzka-Hajnos, Monika and Kowalska, Teresa",
year = "2011",
abstract = "In the previous paper from this series, we proposed mass spectrometric fingerprinting of a complex and volatile botanical sample upon an example of the essential oil derived from Salvia lavandulifolia. In that paper, we compared two variants of fractionation of such a mixture. A simpler one-dimensional variant consisted of the low-temperature thin-layer chromatographic fractionation coupled with mass spectrometric fingerprinting of each separated fraction (1D LT TLC-MS). A more sophisticated variant was the two-dimensional liquid chromatographic system composed of the low-temperature thin-layer chromatography, high-performance liquid chromatography, and mass spectrometric detection (2D LT TLC-LC-MS). In this study, we present an analogous approach to the non-volatile botanical mixtures upon an example of the pharmacologically important phenolic acids and flavonoids selectively extracted from Salvia lavandulifolia. With these non-volatile fractions, the thin-layer chromatographic separations were carried out at ambient temperature (21 +/- 0.5 degrees C). Once again, we compared two variants of fractionation. A simpler one-dimensional variant consisted of the thin-layer chromatographic mode coupled with mass spectrometric fingerprinting of each separated fraction (1D TLC-MS). A more sophisticated variant was the two-dimensional liquid chromatographic system composed of the thin-layer chromatography and high-performance liquid chromatography, with mass spectrometric detection (2D TLC-LC-MS). As expected, the two-dimensional mode proved better performing than the one-dimensional mode (1D TLC-MS). It was concluded that thin-layer chromatography directly or indirectly coupled with mass spectrometric detection can prove very useful in the analysis of the phenolic acid and flavonoid fraction selectively extracted from botanical material.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography and Related Technologies",
title = "Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part Ii. Phenolic Acids and Flavonoids",
volume = "34",
number = "10-11",
pages = "864-887",
doi = "10.1080/10826076.2011.571131"
}

Sajewicz, M., Staszek, D., Natić, M., Wojtal, L., Waksmundzka-Hajnos, M.,& Kowalska, T.. (2011). Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part Ii. Phenolic Acids and Flavonoids. in Journal of Liquid Chromatography and Related Technologies
Taylor & Francis Inc, Philadelphia., 34(10-11), 864-887.
https://doi.org/10.1080/10826076.2011.571131

Sajewicz M, Staszek D, Natić M, Wojtal L, Waksmundzka-Hajnos M, Kowalska T. Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part Ii. Phenolic Acids and Flavonoids. in Journal of Liquid Chromatography and Related Technologies. 2011;34(10-11):864-887.
doi:10.1080/10826076.2011.571131 .

Sajewicz, Mieczyslaw, Staszek, Dorota, Natić, Maja, Wojtal, Lukasz, Waksmundzka-Hajnos, Monika, Kowalska, Teresa, "Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part Ii. Phenolic Acids and Flavonoids" in Journal of Liquid Chromatography and Related Technologies, 34, no. 10-11 (2011):864-887,
https://doi.org/10.1080/10826076.2011.571131 . .

TY  - JOUR
AU  - Sajewicz, Mieczyslaw
AU  - Wojtal, Lukasz
AU  - Natić, Maja
AU  - Staszek, Dorota
AU  - Waksmundzka-Hajnos, Monika
AU  - Kowalska, Teresa
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1347
AB  - In our earlier studies, we proposed the low-temperature thin-layer chromatography with densitometric and mass spectrometric detection for fingerprinting of essential oils derived from several different species from the Salvia genus. Development of the proposed LT-TLC-MS approach was only possible with use of the TLC-MS interface able to couple the chromatographic plate with mass spectrometer. The goal of this study was to develop for the same purpose the two-dimensional liquid chromatographic system, which was only possible with use of the TLC-MS interface. It included the low-temperature thin-layer chromatography coupled with high-performance liquid chromatography, to build an overall LT TLC-LC-MS system. We compared the fingerprinting results for the essential oil of Salvia lavandulifolia obtained with use of the one-dimensional system (1D LT TLC-MS) with those obtained with use of the two-dimensional system (2D LT TLC-LC-MS). It was shown that the 2D approach provides more fingerprints for further investigations than the 1D approach. Moreover, it is also clear that the 2D approach is better suited for identification of individual chemical species contained in a given mixture, due to the simpler patterns of mass spectra obtained from the 2D analytical mode than from the 1D one. However, with the constituents of the essential oil derived from Salvia lavandulifolia, a straightforward identification was not possible, basically due to numerous groups of isomers among the terpenes and terpenoids contained in the examined sample that have the same molecular weights and hence, can give identical m/z signals.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography and Related Technologies
T1  - Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part I. Essential Oils
VL  - 34
IS  - 10-11
SP  - 848
EP  - 863
DO  - 10.1080/10826076.2011.571136
ER  - 

@article{
author = "Sajewicz, Mieczyslaw and Wojtal, Lukasz and Natić, Maja and Staszek, Dorota and Waksmundzka-Hajnos, Monika and Kowalska, Teresa",
year = "2011",
abstract = "In our earlier studies, we proposed the low-temperature thin-layer chromatography with densitometric and mass spectrometric detection for fingerprinting of essential oils derived from several different species from the Salvia genus. Development of the proposed LT-TLC-MS approach was only possible with use of the TLC-MS interface able to couple the chromatographic plate with mass spectrometer. The goal of this study was to develop for the same purpose the two-dimensional liquid chromatographic system, which was only possible with use of the TLC-MS interface. It included the low-temperature thin-layer chromatography coupled with high-performance liquid chromatography, to build an overall LT TLC-LC-MS system. We compared the fingerprinting results for the essential oil of Salvia lavandulifolia obtained with use of the one-dimensional system (1D LT TLC-MS) with those obtained with use of the two-dimensional system (2D LT TLC-LC-MS). It was shown that the 2D approach provides more fingerprints for further investigations than the 1D approach. Moreover, it is also clear that the 2D approach is better suited for identification of individual chemical species contained in a given mixture, due to the simpler patterns of mass spectra obtained from the 2D analytical mode than from the 1D one. However, with the constituents of the essential oil derived from Salvia lavandulifolia, a straightforward identification was not possible, basically due to numerous groups of isomers among the terpenes and terpenoids contained in the examined sample that have the same molecular weights and hence, can give identical m/z signals.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography and Related Technologies",
title = "Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part I. Essential Oils",
volume = "34",
number = "10-11",
pages = "848-863",
doi = "10.1080/10826076.2011.571136"
}

Sajewicz, M., Wojtal, L., Natić, M., Staszek, D., Waksmundzka-Hajnos, M.,& Kowalska, T.. (2011). Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part I. Essential Oils. in Journal of Liquid Chromatography and Related Technologies
Taylor & Francis Inc, Philadelphia., 34(10-11), 848-863.
https://doi.org/10.1080/10826076.2011.571136

Sajewicz M, Wojtal L, Natić M, Staszek D, Waksmundzka-Hajnos M, Kowalska T. Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part I. Essential Oils. in Journal of Liquid Chromatography and Related Technologies. 2011;34(10-11):848-863.
doi:10.1080/10826076.2011.571136 .

Sajewicz, Mieczyslaw, Wojtal, Lukasz, Natić, Maja, Staszek, Dorota, Waksmundzka-Hajnos, Monika, Kowalska, Teresa, "Tlc-Ms Versus Tlc-Lc-Ms Fingerprints of Herbal Extracts. Part I. Essential Oils" in Journal of Liquid Chromatography and Related Technologies, 34, no. 10-11 (2011):848-863,
https://doi.org/10.1080/10826076.2011.571136 . .

TY  - JOUR
AU  - Trifković, Jelena
AU  - Andrić, Filip
AU  - Ristivojević, Petar
AU  - Andrić, Deana
AU  - Tešić, Živoslav Lj.
AU  - Milojković-Opsenica, Dušanka
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1124
AB  - A quantitative structure retention relationship study has been performed to correlate the retention of 33 newly synthesized arylpiperazines with their molecular characteristics, using thin-layer chromatography. Principal component analysis followed by multiple linear regression (MLR), principal component regression (PCR) and partial least squares (PLS) was performed to identify the most important factors, to quantify their influences, and to select descriptors that best describe the behavior of the compounds investigated. The best statistical performance was achieved by applying PLS regression, leading to the lowest value of the standard error (root mean square errors of calibration of 0.159 and cross-validated value RMSE cross-validation = 0.231 units), followed by the PCR (root mean square errors of calibration = 0.195 and RMSE cross-validation = 0.305) and MLR (R(adj)(2) = 0 9499, F = 102.017, mean square error = 0.052 and predicted residual error sum of squares = 2.23). Two factors of the highest influence: surface tension and hydrophilic lipophilic balance appear as the part of obtained models. In addition, polar surface area and hydrophilic surface area are included by both PLS and PCR models. Moreover, log P has been added to the PLS model. Besides, PCR model includes following descriptors: hydrogen bond acceptor, hydrogen bond donor and LUMO energy, whereas topological descriptors: connectivity indices 0 and 2, and valence index 3 are included in the MLR model.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Journal of Separation Science
T1  - Structure-retention relationship study of arylpiperazines by linear multivariate modeling
VL  - 33
IS  - 17-18
SP  - 2619
EP  - 2628
DO  - 10.1002/jssc.201000200
ER  - 

@article{
author = "Trifković, Jelena and Andrić, Filip and Ristivojević, Petar and Andrić, Deana and Tešić, Živoslav Lj. and Milojković-Opsenica, Dušanka",
year = "2010",
abstract = "A quantitative structure retention relationship study has been performed to correlate the retention of 33 newly synthesized arylpiperazines with their molecular characteristics, using thin-layer chromatography. Principal component analysis followed by multiple linear regression (MLR), principal component regression (PCR) and partial least squares (PLS) was performed to identify the most important factors, to quantify their influences, and to select descriptors that best describe the behavior of the compounds investigated. The best statistical performance was achieved by applying PLS regression, leading to the lowest value of the standard error (root mean square errors of calibration of 0.159 and cross-validated value RMSE cross-validation = 0.231 units), followed by the PCR (root mean square errors of calibration = 0.195 and RMSE cross-validation = 0.305) and MLR (R(adj)(2) = 0 9499, F = 102.017, mean square error = 0.052 and predicted residual error sum of squares = 2.23). Two factors of the highest influence: surface tension and hydrophilic lipophilic balance appear as the part of obtained models. In addition, polar surface area and hydrophilic surface area are included by both PLS and PCR models. Moreover, log P has been added to the PLS model. Besides, PCR model includes following descriptors: hydrogen bond acceptor, hydrogen bond donor and LUMO energy, whereas topological descriptors: connectivity indices 0 and 2, and valence index 3 are included in the MLR model.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Journal of Separation Science",
title = "Structure-retention relationship study of arylpiperazines by linear multivariate modeling",
volume = "33",
number = "17-18",
pages = "2619-2628",
doi = "10.1002/jssc.201000200"
}

Trifković, J., Andrić, F., Ristivojević, P., Andrić, D., Tešić, Ž. Lj.,& Milojković-Opsenica, D.. (2010). Structure-retention relationship study of arylpiperazines by linear multivariate modeling. in Journal of Separation Science
Wiley-V C H Verlag Gmbh, Weinheim., 33(17-18), 2619-2628.
https://doi.org/10.1002/jssc.201000200

Trifković J, Andrić F, Ristivojević P, Andrić D, Tešić ŽL, Milojković-Opsenica D. Structure-retention relationship study of arylpiperazines by linear multivariate modeling. in Journal of Separation Science. 2010;33(17-18):2619-2628.
doi:10.1002/jssc.201000200 .

Trifković, Jelena, Andrić, Filip, Ristivojević, Petar, Andrić, Deana, Tešić, Živoslav Lj., Milojković-Opsenica, Dušanka, "Structure-retention relationship study of arylpiperazines by linear multivariate modeling" in Journal of Separation Science, 33, no. 17-18 (2010):2619-2628,
https://doi.org/10.1002/jssc.201000200 . .

TY  - JOUR
AU  - Grgurić-Šipka, Sanja
AU  - Ivanović, Ivanka
AU  - Rakic, Gordana
AU  - Todorović, Nina
AU  - Gligorijević, Nevenka
AU  - Radulović, Siniša
AU  - Arion, Vladimir B.
AU  - Keppler, Bernhard K.
AU  - Tešić, Živoslav Lj.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1058
AB  - Ruthenium(II)-arene complexes of general formulae [(eta(6)-p-cymene)Ru(L1-3)Cl-2], where L1-3 is 3-acetylpyridine (1), 4-acetylpyridine (2) and 2-amino-5-chloropyridine (3), Correspondingly, [(eta(6)-p-cymene)Ru(HL4,5)Cl-2], where HL4 and HL5 are respectively isonicotinic acid (4) and nicotinic acid (5) and [(eta(6)-p-cymene)Ru(HL6-9)Cl], where H2L6-9 represent 2,3-pyridinedicarboxylic acid (6), 2,4-pyidinedicarboxylic acid (7), 2,5-pyridinedicarboxylic acid (8) and 2,6-pyridinedicarboxylic acid (9), were prepared by the reaction of (eta(6)-p-cymene)(2)RuCl2](2) (10) with the corresponding ligand in 1:2 molar ratio in isopropanol. The complexes were characterized by elemental analysis, mass spectrometry, IR and NMR spectroscopies. According to these data the molecules adopt the usual "three-leg piano-stool" geometry which is common for this type of complexes. The structures of I and 7 were determined by X-ray crystallography. The complexes revealed low antiproliferative activity in six investigated tumor cell lines (HeLa, B16, FemX, MDA-MB-361, MDA-MB-453 and LS-174). The reaction of 6 with 9-methyladenine was studied by H-1 NMR, H-1, H-1 COSY and H-1, H-1 NOESY spectroscopy. (C) 2009 Elsevier Masson SAS. All rights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity
VL  - 45
IS  - 3
SP  - 1051
EP  - 1058
DO  - 10.1016/j.ejmech.2009.11.055
ER  - 

@article{
author = "Grgurić-Šipka, Sanja and Ivanović, Ivanka and Rakic, Gordana and Todorović, Nina and Gligorijević, Nevenka and Radulović, Siniša and Arion, Vladimir B. and Keppler, Bernhard K. and Tešić, Živoslav Lj.",
year = "2010",
abstract = "Ruthenium(II)-arene complexes of general formulae [(eta(6)-p-cymene)Ru(L1-3)Cl-2], where L1-3 is 3-acetylpyridine (1), 4-acetylpyridine (2) and 2-amino-5-chloropyridine (3), Correspondingly, [(eta(6)-p-cymene)Ru(HL4,5)Cl-2], where HL4 and HL5 are respectively isonicotinic acid (4) and nicotinic acid (5) and [(eta(6)-p-cymene)Ru(HL6-9)Cl], where H2L6-9 represent 2,3-pyridinedicarboxylic acid (6), 2,4-pyidinedicarboxylic acid (7), 2,5-pyridinedicarboxylic acid (8) and 2,6-pyridinedicarboxylic acid (9), were prepared by the reaction of (eta(6)-p-cymene)(2)RuCl2](2) (10) with the corresponding ligand in 1:2 molar ratio in isopropanol. The complexes were characterized by elemental analysis, mass spectrometry, IR and NMR spectroscopies. According to these data the molecules adopt the usual "three-leg piano-stool" geometry which is common for this type of complexes. The structures of I and 7 were determined by X-ray crystallography. The complexes revealed low antiproliferative activity in six investigated tumor cell lines (HeLa, B16, FemX, MDA-MB-361, MDA-MB-453 and LS-174). The reaction of 6 with 9-methyladenine was studied by H-1 NMR, H-1, H-1 COSY and H-1, H-1 NOESY spectroscopy. (C) 2009 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity",
volume = "45",
number = "3",
pages = "1051-1058",
doi = "10.1016/j.ejmech.2009.11.055"
}

Grgurić-Šipka, S., Ivanović, I., Rakic, G., Todorović, N., Gligorijević, N., Radulović, S., Arion, V. B., Keppler, B. K.,& Tešić, Ž. Lj.. (2010). Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 45(3), 1051-1058.
https://doi.org/10.1016/j.ejmech.2009.11.055

Grgurić-Šipka S, Ivanović I, Rakic G, Todorović N, Gligorijević N, Radulović S, Arion VB, Keppler BK, Tešić ŽL. Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity. in European Journal of Medicinal Chemistry. 2010;45(3):1051-1058.
doi:10.1016/j.ejmech.2009.11.055 .

Grgurić-Šipka, Sanja, Ivanović, Ivanka, Rakic, Gordana, Todorović, Nina, Gligorijević, Nevenka, Radulović, Siniša, Arion, Vladimir B., Keppler, Bernhard K., Tešić, Živoslav Lj., "Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity" in European Journal of Medicinal Chemistry, 45, no. 3 (2010):1051-1058,
https://doi.org/10.1016/j.ejmech.2009.11.055 . .

TY  - JOUR
AU  - Andrić, Filip
AU  - Trifković, Jelena
AU  - Radoičić, Aleksandra
AU  - Šegan, Sandra B.
AU  - Tešić, Živoslav Lj.
AU  - Milojković-Opsenica, Dušanka
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1125
AB  - In order to determine the soil-water partition coefficient for eleven mono- and poly-substituted phenolic compounds, for which there is still no literature data available. the possibility of using thin-layer chromatography (TLC) as a means for rapid and reliable log K-OC estimation was examined A series of chromatographically derived descriptors R-M(0), b, C-0 and PC1 (first principal component), calculated from retention data obtained under reversed-phase conditions, were used for the assessment of models as well as for a direct calibration procedure The final calibration models are discussed with regard to the achieved accuracy and statistical quality, the type of descriptors used and the corresponding chromatographic conditions The estimated log K-OC values of the studied phenols were compared with those obtained by other means (a) the present OECD guideline based on an HPLC technique, (b) the KOCWIN software package, available free of charge from the US Environmental Protection Agency web site and (c) general LSER models established by Nguyen and coworkers, and Poole and coworkers The proposed method showed the best agreement with the results obtained by the OECD procedure, followed by the LSER models of Poole and Nguyen Lower quality correlations were achieved with the KOCWIN calculated values, especially those predicted by molecular connectivity indices. (C) 2010 Elsevier Ltd All rights reserved
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Chemosphere
T1  - Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography
VL  - 81
IS  - 3
SP  - 299
EP  - 305
DO  - 10.1016/j.chemosphere.2010.07.049
ER  - 

@article{
author = "Andrić, Filip and Trifković, Jelena and Radoičić, Aleksandra and Šegan, Sandra B. and Tešić, Živoslav Lj. and Milojković-Opsenica, Dušanka",
year = "2010",
abstract = "In order to determine the soil-water partition coefficient for eleven mono- and poly-substituted phenolic compounds, for which there is still no literature data available. the possibility of using thin-layer chromatography (TLC) as a means for rapid and reliable log K-OC estimation was examined A series of chromatographically derived descriptors R-M(0), b, C-0 and PC1 (first principal component), calculated from retention data obtained under reversed-phase conditions, were used for the assessment of models as well as for a direct calibration procedure The final calibration models are discussed with regard to the achieved accuracy and statistical quality, the type of descriptors used and the corresponding chromatographic conditions The estimated log K-OC values of the studied phenols were compared with those obtained by other means (a) the present OECD guideline based on an HPLC technique, (b) the KOCWIN software package, available free of charge from the US Environmental Protection Agency web site and (c) general LSER models established by Nguyen and coworkers, and Poole and coworkers The proposed method showed the best agreement with the results obtained by the OECD procedure, followed by the LSER models of Poole and Nguyen Lower quality correlations were achieved with the KOCWIN calculated values, especially those predicted by molecular connectivity indices. (C) 2010 Elsevier Ltd All rights reserved",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Chemosphere",
title = "Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography",
volume = "81",
number = "3",
pages = "299-305",
doi = "10.1016/j.chemosphere.2010.07.049"
}

Andrić, F., Trifković, J., Radoičić, A., Šegan, S. B., Tešić, Ž. Lj.,& Milojković-Opsenica, D.. (2010). Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography. in Chemosphere
Pergamon-Elsevier Science Ltd, Oxford., 81(3), 299-305.
https://doi.org/10.1016/j.chemosphere.2010.07.049

Andrić F, Trifković J, Radoičić A, Šegan SB, Tešić ŽL, Milojković-Opsenica D. Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography. in Chemosphere. 2010;81(3):299-305.
doi:10.1016/j.chemosphere.2010.07.049 .

Andrić, Filip, Trifković, Jelena, Radoičić, Aleksandra, Šegan, Sandra B., Tešić, Živoslav Lj., Milojković-Opsenica, Dušanka, "Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography" in Chemosphere, 81, no. 3 (2010):299-305,
https://doi.org/10.1016/j.chemosphere.2010.07.049 . .

TY  - JOUR
AU  - Šumar-Ristović, Maja
AU  - Minić, Dragica M.
AU  - Poleti, Dejan
AU  - Miodragović, Zoran
AU  - Miodragović Đenana U.
AU  - Anđelković, Katarina K.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1117
AB  - Thermal behavior of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand was investigated using the results of TG, DSC and DTG analysis obtained at different heating rates (2.5 to 30 A degrees C min(-1)), from room temperature to about 900 A degrees C. Mechanisms of complex degradation, as well as enthalpies of the degradation processes were determined. It is shown that thermal stability of investigated complexes correlates with their crystal structures, especially with the presence of crystallization and coordinated water molecules. The values of dehydration enthalpies are discussed and correlated with composition of the complexes. Kissinger's, Ozawa's, and Friedman's isoconversion methods were used for the determination of kinetic parameters: the pre-exponential factor A and the apparent activation energy E (a). For all three complexes and all steps of degradation, the values of kinetics parameters obtained by Kissinger's and Ozawa's methods are in good agreement. The results obtained by Friedman's method showed that some decomposition steps are simple and some others are complex ones.
PB  - Springer, Dordrecht
T2  - Journal of Thermal Analysis and Calorimetry
T1  - Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand
VL  - 102
IS  - 1
SP  - 83
EP  - 90
DO  - 10.1007/s10973-010-0748-2
ER  - 

@article{
author = "Šumar-Ristović, Maja and Minić, Dragica M. and Poleti, Dejan and Miodragović, Zoran and Miodragović Đenana U. and Anđelković, Katarina K.",
year = "2010",
abstract = "Thermal behavior of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand was investigated using the results of TG, DSC and DTG analysis obtained at different heating rates (2.5 to 30 A degrees C min(-1)), from room temperature to about 900 A degrees C. Mechanisms of complex degradation, as well as enthalpies of the degradation processes were determined. It is shown that thermal stability of investigated complexes correlates with their crystal structures, especially with the presence of crystallization and coordinated water molecules. The values of dehydration enthalpies are discussed and correlated with composition of the complexes. Kissinger's, Ozawa's, and Friedman's isoconversion methods were used for the determination of kinetic parameters: the pre-exponential factor A and the apparent activation energy E (a). For all three complexes and all steps of degradation, the values of kinetics parameters obtained by Kissinger's and Ozawa's methods are in good agreement. The results obtained by Friedman's method showed that some decomposition steps are simple and some others are complex ones.",
publisher = "Springer, Dordrecht",
journal = "Journal of Thermal Analysis and Calorimetry",
title = "Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand",
volume = "102",
number = "1",
pages = "83-90",
doi = "10.1007/s10973-010-0748-2"
}

Šumar-Ristović, M., Minić, D. M., Poleti, D., Miodragović, Z., Miodragović Đenana U.,& Anđelković, K. K.. (2010). Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand. in Journal of Thermal Analysis and Calorimetry
Springer, Dordrecht., 102(1), 83-90.
https://doi.org/10.1007/s10973-010-0748-2

Šumar-Ristović M, Minić DM, Poleti D, Miodragović Z, Miodragović Đenana U., Anđelković KK. Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand. in Journal of Thermal Analysis and Calorimetry. 2010;102(1):83-90.
doi:10.1007/s10973-010-0748-2 .

Šumar-Ristović, Maja, Minić, Dragica M., Poleti, Dejan, Miodragović, Zoran, Miodragović Đenana U., Anđelković, Katarina K., "Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand" in Journal of Thermal Analysis and Calorimetry, 102, no. 1 (2010):83-90,
https://doi.org/10.1007/s10973-010-0748-2 . .

TY  - JOUR
AU  - Filipović, Nenad R.
AU  - Todorović, Tamara
AU  - Marković, Rade
AU  - Marinković, Aleksandar
AU  - Tufegdžić, Srđan
AU  - Gođevac, Dejan
AU  - Anđelković, Katarina K.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1099
AB  - Condensation derivatives of ethyl hydrazinoacetate with 2-formylpyridine and quinoline-2-carboxaldehyde were synthesized. Pd(II), Pt(II) and Cd(II) complexes with the 2-formylpyridine derivative and a Cd(II) complex with the quinoline-2-carboxaldehyde derivative were synthesized and characterized by spectroscopic techniques. In the complexes, both ligands are coordinated in neutral NN bidentate modes, while the remaining two coordination sites are occupied by chloride. All compounds showed biological activity when tested against Escherichia coli, Bacillus subtilis and Staphylococcus aureus.
PB  - Springer, Dordrecht
T2  - Transition Metal Chemistry
T1  - Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)
VL  - 35
IS  - 6
SP  - 765
EP  - 772
DO  - 10.1007/s11243-010-9391-9
ER  - 

@article{
author = "Filipović, Nenad R. and Todorović, Tamara and Marković, Rade and Marinković, Aleksandar and Tufegdžić, Srđan and Gođevac, Dejan and Anđelković, Katarina K.",
year = "2010",
abstract = "Condensation derivatives of ethyl hydrazinoacetate with 2-formylpyridine and quinoline-2-carboxaldehyde were synthesized. Pd(II), Pt(II) and Cd(II) complexes with the 2-formylpyridine derivative and a Cd(II) complex with the quinoline-2-carboxaldehyde derivative were synthesized and characterized by spectroscopic techniques. In the complexes, both ligands are coordinated in neutral NN bidentate modes, while the remaining two coordination sites are occupied by chloride. All compounds showed biological activity when tested against Escherichia coli, Bacillus subtilis and Staphylococcus aureus.",
publisher = "Springer, Dordrecht",
journal = "Transition Metal Chemistry",
title = "Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)",
volume = "35",
number = "6",
pages = "765-772",
doi = "10.1007/s11243-010-9391-9"
}

Filipović, N. R., Todorović, T., Marković, R., Marinković, A., Tufegdžić, S., Gođevac, D.,& Anđelković, K. K.. (2010). Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II). in Transition Metal Chemistry
Springer, Dordrecht., 35(6), 765-772.
https://doi.org/10.1007/s11243-010-9391-9

Filipović NR, Todorović T, Marković R, Marinković A, Tufegdžić S, Gođevac D, Anđelković KK. Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II). in Transition Metal Chemistry. 2010;35(6):765-772.
doi:10.1007/s11243-010-9391-9 .

Filipović, Nenad R., Todorović, Tamara, Marković, Rade, Marinković, Aleksandar, Tufegdžić, Srđan, Gođevac, Dejan, Anđelković, Katarina K., "Synthesis, characterization and biological activities of N-heteroaromatic hydrazones and their complexes with Pd(II), Pt(II) and Cd(II)" in Transition Metal Chemistry, 35, no. 6 (2010):765-772,
https://doi.org/10.1007/s11243-010-9391-9 . .

TY  - JOUR
AU  - Jeremić, Dejan
AU  - Kaluđerović, Goran N.
AU  - Gomez-Ruiz, Santiago
AU  - Brčeski, Ilija
AU  - Kasalica, Becko
AU  - Leovac, Vukadin M.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1049
AB  - Novel hexaaquametal(II) bis(D-camphor-10-sulfonates) with Mn(II), Fe(II), and Co(II) ions were synthesized as large single crystals. During the crystallization process, suitable metal wires were used to induce crystallization. Crystals were analyzed by means of X-ray analysis, IR spectrophotometry, and solid state UV-vis spectroscopy. The obtained substances are stable in air, and their UV-vis spectra imply their potential use as optical filters and optical materials.
PB  - Amer Chemical Soc, Washington
T2  - Crystal Growth and Design
T1  - Large Single Crystals of Isomorphous Hexaaquametal(II) D-Camphor-10-sulfonates
VL  - 10
IS  - 2
SP  - 559
EP  - 563
DO  - 10.1021/cg9009288
ER  - 

@article{
author = "Jeremić, Dejan and Kaluđerović, Goran N. and Gomez-Ruiz, Santiago and Brčeski, Ilija and Kasalica, Becko and Leovac, Vukadin M.",
year = "2010",
abstract = "Novel hexaaquametal(II) bis(D-camphor-10-sulfonates) with Mn(II), Fe(II), and Co(II) ions were synthesized as large single crystals. During the crystallization process, suitable metal wires were used to induce crystallization. Crystals were analyzed by means of X-ray analysis, IR spectrophotometry, and solid state UV-vis spectroscopy. The obtained substances are stable in air, and their UV-vis spectra imply their potential use as optical filters and optical materials.",
publisher = "Amer Chemical Soc, Washington",
journal = "Crystal Growth and Design",
title = "Large Single Crystals of Isomorphous Hexaaquametal(II) D-Camphor-10-sulfonates",
volume = "10",
number = "2",
pages = "559-563",
doi = "10.1021/cg9009288"
}

Jeremić, D., Kaluđerović, G. N., Gomez-Ruiz, S., Brčeski, I., Kasalica, B.,& Leovac, V. M.. (2010). Large Single Crystals of Isomorphous Hexaaquametal(II) D-Camphor-10-sulfonates. in Crystal Growth and Design
Amer Chemical Soc, Washington., 10(2), 559-563.
https://doi.org/10.1021/cg9009288

Jeremić D, Kaluđerović GN, Gomez-Ruiz S, Brčeski I, Kasalica B, Leovac VM. Large Single Crystals of Isomorphous Hexaaquametal(II) D-Camphor-10-sulfonates. in Crystal Growth and Design. 2010;10(2):559-563.
doi:10.1021/cg9009288 .

Jeremić, Dejan, Kaluđerović, Goran N., Gomez-Ruiz, Santiago, Brčeski, Ilija, Kasalica, Becko, Leovac, Vukadin M., "Large Single Crystals of Isomorphous Hexaaquametal(II) D-Camphor-10-sulfonates" in Crystal Growth and Design, 10, no. 2 (2010):559-563,
https://doi.org/10.1021/cg9009288 . .

TY  - JOUR
AU  - Baošić, Rada
AU  - Radojevic, Ana D.
AU  - Tešić, Živoslav Lj.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1077
AB  - Quantitative structure retention relationships for a series of 30 mixed beta-diketonato complexes of cobalt(III), chromium(III) and ruthenium(III) were derived by multiple linear regression analyses using molecular descriptors obtained by quantum chemical calculations. The retention parameters were obtained by thin layer chromatography on silica gel using mono and two-component solvent systems. The molecular descriptors included in the multiple linear regression analysis were molecular weight, molecular volume, surface area, hydrophilic lipophilic balance, percent hydrophilic surface area, dipole moment, polarizability, refractivity, energy of the highest occupied molecular orbital and energy of the lowest unoccupied molecular orbital. High agreement between the experimental and predicted retention parameters was obtained when polarizability and the hydrophilic lipophilic balance were used as the molecular descriptors. Comparison of the models with those established on polyacrylonitrile showed that the structure of the sorbent is responsible for the chromatographic behaviour of the same compounds. The presented models can be used for the prediction of the retention of new solutes in screening chromatographic systems.
AB  - U ovom radu kvantifikovan je odnos strukture i retencije 30 mešovitih β-diketonato kompleksa kobalta(III), hroma(III) i rutenijuma(III) primenom multilinearne regresione analize korišćenjem molekulskih deskriptora, koji su dobijeni pomoću kvantno-hemijskih izračunavanja. Retencioni parametri su dobijeni tankoslojnom hromatografijom na silika-gelu primenom mono-i dvokomponetnih rastvarača. Molekulski deskriptori koji su uključeni u multilinearnu regresionu analizu su molekulska težina, molekulska zapremina, površina, hidrofilni-lipofilni balans, procenat hidrofilne površine, dipolni momenat, polarizabilnost, refraktivnost, energija najviše zauzete molekulske orbitale i energija najniže prazne molekulske orbitale. Dobijena je zadovoljavajuća korelacija između eksperimentalnih retencionih parametara i retencionih parametara predviđenih postavljenim modelima, koji sadrže polarizabilnost i hidrofilni-lipofilni balans kao deskriptore. Poređenja ovih modela sa modelima dobijenim na poliakrilonitrilnom sorbentu, za ista jedinjenja, pokazuju da je struktura sorbenta odgovorna za hromatografsko ponašanje. Ovi modeli se mogu koristiti za predviđanje retencije novih jedinjenja u datim hromatografskim sistemima.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Prediction of the retention of beta-diketonato complexes in TLC systems on silica gel by quantitative structure-retention relationships
T1  - Predviđanje retencije β-diketonato kompleksa u TLC sistemima na silika-gelu primenom kvantitativnog odnosa strukture i retencije
VL  - 75
IS  - 4
SP  - 513
EP  - 521
DO  - 10.2298/JSC090225002B
ER  - 

@article{
author = "Baošić, Rada and Radojevic, Ana D. and Tešić, Živoslav Lj.",
year = "2010",
abstract = "Quantitative structure retention relationships for a series of 30 mixed beta-diketonato complexes of cobalt(III), chromium(III) and ruthenium(III) were derived by multiple linear regression analyses using molecular descriptors obtained by quantum chemical calculations. The retention parameters were obtained by thin layer chromatography on silica gel using mono and two-component solvent systems. The molecular descriptors included in the multiple linear regression analysis were molecular weight, molecular volume, surface area, hydrophilic lipophilic balance, percent hydrophilic surface area, dipole moment, polarizability, refractivity, energy of the highest occupied molecular orbital and energy of the lowest unoccupied molecular orbital. High agreement between the experimental and predicted retention parameters was obtained when polarizability and the hydrophilic lipophilic balance were used as the molecular descriptors. Comparison of the models with those established on polyacrylonitrile showed that the structure of the sorbent is responsible for the chromatographic behaviour of the same compounds. The presented models can be used for the prediction of the retention of new solutes in screening chromatographic systems., U ovom radu kvantifikovan je odnos strukture i retencije 30 mešovitih β-diketonato kompleksa kobalta(III), hroma(III) i rutenijuma(III) primenom multilinearne regresione analize korišćenjem molekulskih deskriptora, koji su dobijeni pomoću kvantno-hemijskih izračunavanja. Retencioni parametri su dobijeni tankoslojnom hromatografijom na silika-gelu primenom mono-i dvokomponetnih rastvarača. Molekulski deskriptori koji su uključeni u multilinearnu regresionu analizu su molekulska težina, molekulska zapremina, površina, hidrofilni-lipofilni balans, procenat hidrofilne površine, dipolni momenat, polarizabilnost, refraktivnost, energija najviše zauzete molekulske orbitale i energija najniže prazne molekulske orbitale. Dobijena je zadovoljavajuća korelacija između eksperimentalnih retencionih parametara i retencionih parametara predviđenih postavljenim modelima, koji sadrže polarizabilnost i hidrofilni-lipofilni balans kao deskriptore. Poređenja ovih modela sa modelima dobijenim na poliakrilonitrilnom sorbentu, za ista jedinjenja, pokazuju da je struktura sorbenta odgovorna za hromatografsko ponašanje. Ovi modeli se mogu koristiti za predviđanje retencije novih jedinjenja u datim hromatografskim sistemima.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Prediction of the retention of beta-diketonato complexes in TLC systems on silica gel by quantitative structure-retention relationships, Predviđanje retencije β-diketonato kompleksa u TLC sistemima na silika-gelu primenom kvantitativnog odnosa strukture i retencije",
volume = "75",
number = "4",
pages = "513-521",
doi = "10.2298/JSC090225002B"
}

Baošić, R., Radojevic, A. D.,& Tešić, Ž. Lj.. (2010). Prediction of the retention of beta-diketonato complexes in TLC systems on silica gel by quantitative structure-retention relationships. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 75(4), 513-521.
https://doi.org/10.2298/JSC090225002B

Baošić R, Radojevic AD, Tešić ŽL. Prediction of the retention of beta-diketonato complexes in TLC systems on silica gel by quantitative structure-retention relationships. in Journal of the Serbian Chemical Society. 2010;75(4):513-521.
doi:10.2298/JSC090225002B .

Baošić, Rada, Radojevic, Ana D., Tešić, Živoslav Lj., "Prediction of the retention of beta-diketonato complexes in TLC systems on silica gel by quantitative structure-retention relationships" in Journal of the Serbian Chemical Society, 75, no. 4 (2010):513-521,
https://doi.org/10.2298/JSC090225002B . .

TY  - JOUR
AU  - Baošić, Rada
AU  - Radojevic, Ana
AU  - Tripkovic, Tatjana
AU  - Aburas, Najat M.
AU  - Tešić, Živoslav Lj.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1061
AB  - Mathematical models which define the effects of molecular properties on the retention and lipophilicity and prediction lipophilicity of some Schiff base ligands, and complexes with copper(II) and nickel(II) were developed. Following molecular descriptors were calculated: molecular volume, surface area, energy of the highest occupied/lowest unoccupied molecular orbital, dipole moment, refractivity, polarizability, hydrophilic-lipophilic balance, and lipophilicity parameters, which are correlated with chromatographically determinated lipophilicity parameters. A multiple linear regression procedure was used to derive the models. High agreement between experimental and predicted values obtained in this validation procedure indicates the good quality of the derived models.
PB  - Springer Heidelberg, Heidelberg
T2  - Chromatographia
T1  - RP-TLC Quantitative Retention-Property Relationships Studies of Some Schiff Base Ligands and Their Complexes
VL  - 72
IS  - 5-6
SP  - 545
EP  - 549
DO  - 10.1365/s10337-010-1664-0
ER  - 

@article{
author = "Baošić, Rada and Radojevic, Ana and Tripkovic, Tatjana and Aburas, Najat M. and Tešić, Živoslav Lj.",
year = "2010",
abstract = "Mathematical models which define the effects of molecular properties on the retention and lipophilicity and prediction lipophilicity of some Schiff base ligands, and complexes with copper(II) and nickel(II) were developed. Following molecular descriptors were calculated: molecular volume, surface area, energy of the highest occupied/lowest unoccupied molecular orbital, dipole moment, refractivity, polarizability, hydrophilic-lipophilic balance, and lipophilicity parameters, which are correlated with chromatographically determinated lipophilicity parameters. A multiple linear regression procedure was used to derive the models. High agreement between experimental and predicted values obtained in this validation procedure indicates the good quality of the derived models.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Chromatographia",
title = "RP-TLC Quantitative Retention-Property Relationships Studies of Some Schiff Base Ligands and Their Complexes",
volume = "72",
number = "5-6",
pages = "545-549",
doi = "10.1365/s10337-010-1664-0"
}

Baošić, R., Radojevic, A., Tripkovic, T., Aburas, N. M.,& Tešić, Ž. Lj.. (2010). RP-TLC Quantitative Retention-Property Relationships Studies of Some Schiff Base Ligands and Their Complexes. in Chromatographia
Springer Heidelberg, Heidelberg., 72(5-6), 545-549.
https://doi.org/10.1365/s10337-010-1664-0

Baošić R, Radojevic A, Tripkovic T, Aburas NM, Tešić ŽL. RP-TLC Quantitative Retention-Property Relationships Studies of Some Schiff Base Ligands and Their Complexes. in Chromatographia. 2010;72(5-6):545-549.
doi:10.1365/s10337-010-1664-0 .

Baošić, Rada, Radojevic, Ana, Tripkovic, Tatjana, Aburas, Najat M., Tešić, Živoslav Lj., "RP-TLC Quantitative Retention-Property Relationships Studies of Some Schiff Base Ligands and Their Complexes" in Chromatographia, 72, no. 5-6 (2010):545-549,
https://doi.org/10.1365/s10337-010-1664-0 . .

TY  - JOUR
AU  - Jeremić, Dejan
AU  - Kaluđerović, Goran N.
AU  - Gomez-Ruiz, Santiago
AU  - Brčeski, Ilija
AU  - Anđelković, Katarina K.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/620
AB  - The structure of the title compound, [Ca(C(10)H(15)O(4)S)(2)(H(2)O)(4)], is the first example in which two d-camphor-10-sulfonate anions are coordinated to a metal ion, in this case with direct Ca-O bonding. The molecule has crystallographically imposed twofold symmetry with the Ca atom on the twofold axis. Hydrogen bonds are formed between the coordinated water molecules and the O atoms of the SO(3)(-) groups of adjacent molecules, leading to the formation of a two-dimensional layered network. The compound displays sharp wavelength-selective transparency in the UV-visible spectrum, offering the potential for application as an optical filter.
PB  - Wiley-Blackwell Publishing, Inc, Malden
T2  - Acta Crystallographica. Section C: Crystal Structure Communications
T1  - Tetraaquabis(D-camphor-10-sulfonato)calcium(II)
VL  - 65
DO  - 10.1107/S0108270109004193
ER  - 

@article{
author = "Jeremić, Dejan and Kaluđerović, Goran N. and Gomez-Ruiz, Santiago and Brčeski, Ilija and Anđelković, Katarina K.",
year = "2009",
abstract = "The structure of the title compound, [Ca(C(10)H(15)O(4)S)(2)(H(2)O)(4)], is the first example in which two d-camphor-10-sulfonate anions are coordinated to a metal ion, in this case with direct Ca-O bonding. The molecule has crystallographically imposed twofold symmetry with the Ca atom on the twofold axis. Hydrogen bonds are formed between the coordinated water molecules and the O atoms of the SO(3)(-) groups of adjacent molecules, leading to the formation of a two-dimensional layered network. The compound displays sharp wavelength-selective transparency in the UV-visible spectrum, offering the potential for application as an optical filter.",
publisher = "Wiley-Blackwell Publishing, Inc, Malden",
journal = "Acta Crystallographica. Section C: Crystal Structure Communications",
title = "Tetraaquabis(D-camphor-10-sulfonato)calcium(II)",
volume = "65",
doi = "10.1107/S0108270109004193"
}

Jeremić, D., Kaluđerović, G. N., Gomez-Ruiz, S., Brčeski, I.,& Anđelković, K. K.. (2009). Tetraaquabis(D-camphor-10-sulfonato)calcium(II). in Acta Crystallographica. Section C: Crystal Structure Communications
Wiley-Blackwell Publishing, Inc, Malden., 65.
https://doi.org/10.1107/S0108270109004193

Jeremić D, Kaluđerović GN, Gomez-Ruiz S, Brčeski I, Anđelković KK. Tetraaquabis(D-camphor-10-sulfonato)calcium(II). in Acta Crystallographica. Section C: Crystal Structure Communications. 2009;65.
doi:10.1107/S0108270109004193 .

Jeremić, Dejan, Kaluđerović, Goran N., Gomez-Ruiz, Santiago, Brčeski, Ilija, Anđelković, Katarina K., "Tetraaquabis(D-camphor-10-sulfonato)calcium(II)" in Acta Crystallographica. Section C: Crystal Structure Communications, 65 (2009),
https://doi.org/10.1107/S0108270109004193 . .

TY  - JOUR
AU  - Atrrog, Abubaker A. B.
AU  - Natić, Maja
AU  - Tosti, Tomislav
AU  - Milojković-Opsenica, Dušanka
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Milosavljević, Slobodan M.
AU  - Lazić, Milan
AU  - Radulović, Siniša
AU  - Tešić, Živoslav Lj.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/609
AB  - In this study 10 guaianolide-type sesquiterpene gamma-lactones named amphoricarpolides, isolated from the aerial parts of two endemic subspecies of Amphoricarpos neumayeri (ssp. neumayeri and ssp. murbeckii Bosnjak), were investigated by means of reversed-phase thin-layer chromatography. Methanol-water and tetrahydrofuran-water binary mixtures were used as mobile phase in order to determine lipophilicity parameters R(M)(0) and C(0). Some of the investigated compounds were screened for their cytotoxic activity against HeLa and B16 cells. Chromatographically obtained lipophilicity parameters were correlated with calculated logP values and IC(50) values. Principal component analysis identified the dominant pattern in the chromatographically obtained data. Copyright (C) 2008 John Wiley & Sons, Ltd.
PB  - John Wiley & Sons Ltd, Chichester
T2  - Biomedical Chromatography
T1  - Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro
VL  - 23
IS  - 3
SP  - 250
EP  - 256
DO  - 10.1002/bmc.1091
ER  - 

@article{
author = "Atrrog, Abubaker A. B. and Natić, Maja and Tosti, Tomislav and Milojković-Opsenica, Dušanka and Đorđević, Iris and Tešević, Vele and Jadranin, Milka and Milosavljević, Slobodan M. and Lazić, Milan and Radulović, Siniša and Tešić, Živoslav Lj.",
year = "2009",
abstract = "In this study 10 guaianolide-type sesquiterpene gamma-lactones named amphoricarpolides, isolated from the aerial parts of two endemic subspecies of Amphoricarpos neumayeri (ssp. neumayeri and ssp. murbeckii Bosnjak), were investigated by means of reversed-phase thin-layer chromatography. Methanol-water and tetrahydrofuran-water binary mixtures were used as mobile phase in order to determine lipophilicity parameters R(M)(0) and C(0). Some of the investigated compounds were screened for their cytotoxic activity against HeLa and B16 cells. Chromatographically obtained lipophilicity parameters were correlated with calculated logP values and IC(50) values. Principal component analysis identified the dominant pattern in the chromatographically obtained data. Copyright (C) 2008 John Wiley & Sons, Ltd.",
publisher = "John Wiley & Sons Ltd, Chichester",
journal = "Biomedical Chromatography",
title = "Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro",
volume = "23",
number = "3",
pages = "250-256",
doi = "10.1002/bmc.1091"
}

Atrrog, A. A. B., Natić, M., Tosti, T., Milojković-Opsenica, D., Đorđević, I., Tešević, V., Jadranin, M., Milosavljević, S. M., Lazić, M., Radulović, S.,& Tešić, Ž. Lj.. (2009). Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro. in Biomedical Chromatography
John Wiley & Sons Ltd, Chichester., 23(3), 250-256.
https://doi.org/10.1002/bmc.1091

Atrrog AAB, Natić M, Tosti T, Milojković-Opsenica D, Đorđević I, Tešević V, Jadranin M, Milosavljević SM, Lazić M, Radulović S, Tešić ŽL. Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro. in Biomedical Chromatography. 2009;23(3):250-256.
doi:10.1002/bmc.1091 .

Atrrog, Abubaker A. B., Natić, Maja, Tosti, Tomislav, Milojković-Opsenica, Dušanka, Đorđević, Iris, Tešević, Vele, Jadranin, Milka, Milosavljević, Slobodan M., Lazić, Milan, Radulović, Siniša, Tešić, Živoslav Lj., "Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro" in Biomedical Chromatography, 23, no. 3 (2009):250-256,
https://doi.org/10.1002/bmc.1091 . .

TY  - JOUR
AU  - Rakic, Gordana M.
AU  - Grgurić-Šipka, Sanja
AU  - Kaluđerović, Goran N.
AU  - Gomez-Ruiz, Santiago
AU  - Bjelogrlić, Snežana K.
AU  - Radulović, Siniša
AU  - Tešić, Živoslav Lj.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/630
AB  - Novel complexes of platinum(II) with 3- (1) or 4-acetylpyridine (2) have been synthesized and characterized by elemental analyses, IR, H-1 and C-13 NMR spectroscopy. Single crystal X-ray diffraction revealed the trans geometry of complex 2. DFT calculations confirm formation of trans isomers for both complexes. The complexes have been tested for their cytotoxicity against HeLa (human cervical cancer), U2OS (human osteosarcoma), U2OScisR (human osteosarcoma cisplatin resistant), B16 (murine melanoma), MDA-453, MDA-361, and MCF-7 (human breast cancer), LS-174 (human colon cancer) and Femx (human melanoma) cell lines. The most promising compound trans-dichloridobis(4-acetylpyridine)platinum(II) (2) overcomes cisplatin resistance of U2OScisR cells after 48 h of drug exposure. (C) 2008 Elsevier Masson SAS. All rights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2  - European Journal of Medicinal Chemistry
T1  - Novel trans-dichloridoplatinum(II) complexes with 3-and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity
VL  - 44
IS  - 5
SP  - 1921
EP  - 1925
DO  - 10.1016/j.ejmech.2008.11.004
ER  - 

@article{
author = "Rakic, Gordana M. and Grgurić-Šipka, Sanja and Kaluđerović, Goran N. and Gomez-Ruiz, Santiago and Bjelogrlić, Snežana K. and Radulović, Siniša and Tešić, Živoslav Lj.",
year = "2009",
abstract = "Novel complexes of platinum(II) with 3- (1) or 4-acetylpyridine (2) have been synthesized and characterized by elemental analyses, IR, H-1 and C-13 NMR spectroscopy. Single crystal X-ray diffraction revealed the trans geometry of complex 2. DFT calculations confirm formation of trans isomers for both complexes. The complexes have been tested for their cytotoxicity against HeLa (human cervical cancer), U2OS (human osteosarcoma), U2OScisR (human osteosarcoma cisplatin resistant), B16 (murine melanoma), MDA-453, MDA-361, and MCF-7 (human breast cancer), LS-174 (human colon cancer) and Femx (human melanoma) cell lines. The most promising compound trans-dichloridobis(4-acetylpyridine)platinum(II) (2) overcomes cisplatin resistance of U2OScisR cells after 48 h of drug exposure. (C) 2008 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "Novel trans-dichloridoplatinum(II) complexes with 3-and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity",
volume = "44",
number = "5",
pages = "1921-1925",
doi = "10.1016/j.ejmech.2008.11.004"
}

Rakic, G. M., Grgurić-Šipka, S., Kaluđerović, G. N., Gomez-Ruiz, S., Bjelogrlić, S. K., Radulović, S.,& Tešić, Ž. Lj.. (2009). Novel trans-dichloridoplatinum(II) complexes with 3-and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Paris., 44(5), 1921-1925.
https://doi.org/10.1016/j.ejmech.2008.11.004

Rakic GM, Grgurić-Šipka S, Kaluđerović GN, Gomez-Ruiz S, Bjelogrlić SK, Radulović S, Tešić ŽL. Novel trans-dichloridoplatinum(II) complexes with 3-and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity. in European Journal of Medicinal Chemistry. 2009;44(5):1921-1925.
doi:10.1016/j.ejmech.2008.11.004 .

Rakic, Gordana M., Grgurić-Šipka, Sanja, Kaluđerović, Goran N., Gomez-Ruiz, Santiago, Bjelogrlić, Snežana K., Radulović, Siniša, Tešić, Živoslav Lj., "Novel trans-dichloridoplatinum(II) complexes with 3-and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity" in European Journal of Medicinal Chemistry, 44, no. 5 (2009):1921-1925,
https://doi.org/10.1016/j.ejmech.2008.11.004 . .

TY  - JOUR
AU  - Filipović, Nenad R.
AU  - Borrmann, Horst
AU  - Todorović, Tamara
AU  - Borna, Marija
AU  - Spasojević, Vojislav
AU  - Sladić, Dušan
AU  - Novaković, Irena T.
AU  - Anđelković, Katarina K.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/629
AB  - Three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine or 2-quinolinecarboxaldehyde with ethyl hydrazinoacetate hydrochloride were synthesized. X-ray crystal structures of all three complexes were determined. Crystallographic data indicate a common basis of the structures with some major differences. Both pyridine derivatives form complexes of the type [CuCl2L] with distorted square-planar geometry around copper(II), but show a decisive difference in the side chain orientation. The quinoline derivative forms a dimeric complex of type [Cu2Cl4L2] with distorted trigonal bipyramidal geometry around copper(II), but a rather short Cu center dot center dot center dot Cu contact, which is reflected in its magnetic properties. All three complexes showed antibacterial activity. (c) 2008 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Sa, Lausanne
T2  - Inorganica Chimica Acta
T1  - Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity
VL  - 362
IS  - 6
SP  - 1996
EP  - 2000
DO  - 10.1016/j.ica.2008.09.019
ER  - 

@article{
author = "Filipović, Nenad R. and Borrmann, Horst and Todorović, Tamara and Borna, Marija and Spasojević, Vojislav and Sladić, Dušan and Novaković, Irena T. and Anđelković, Katarina K.",
year = "2009",
abstract = "Three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine or 2-quinolinecarboxaldehyde with ethyl hydrazinoacetate hydrochloride were synthesized. X-ray crystal structures of all three complexes were determined. Crystallographic data indicate a common basis of the structures with some major differences. Both pyridine derivatives form complexes of the type [CuCl2L] with distorted square-planar geometry around copper(II), but show a decisive difference in the side chain orientation. The quinoline derivative forms a dimeric complex of type [Cu2Cl4L2] with distorted trigonal bipyramidal geometry around copper(II), but a rather short Cu center dot center dot center dot Cu contact, which is reflected in its magnetic properties. All three complexes showed antibacterial activity. (c) 2008 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Inorganica Chimica Acta",
title = "Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity",
volume = "362",
number = "6",
pages = "1996-2000",
doi = "10.1016/j.ica.2008.09.019"
}

Filipović, N. R., Borrmann, H., Todorović, T., Borna, M., Spasojević, V., Sladić, D., Novaković, I. T.,& Anđelković, K. K.. (2009). Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity. in Inorganica Chimica Acta
Elsevier Science Sa, Lausanne., 362(6), 1996-2000.
https://doi.org/10.1016/j.ica.2008.09.019

Filipović NR, Borrmann H, Todorović T, Borna M, Spasojević V, Sladić D, Novaković IT, Anđelković KK. Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity. in Inorganica Chimica Acta. 2009;362(6):1996-2000.
doi:10.1016/j.ica.2008.09.019 .

Filipović, Nenad R., Borrmann, Horst, Todorović, Tamara, Borna, Marija, Spasojević, Vojislav, Sladić, Dušan, Novaković, Irena T., Anđelković, Katarina K., "Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity" in Inorganica Chimica Acta, 362, no. 6 (2009):1996-2000,
https://doi.org/10.1016/j.ica.2008.09.019 . .

TY  - JOUR
AU  - Odovic, Jadranka
AU  - Aleksic, Mirjana
AU  - Stojimirovic, Biljana
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav Lj.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1004
AB  - The separation and chromatographic behaviour of five ACE (angiotensin converting enzyme) inhibitors and their four active metabolites were investigated by normal-phase thin-layer chromatography on silica using several mono- and binary non-aqueous solvent systems. The linear relationship between the R(M) values and the composition 0 of employed mobile phase was obtained. The hydrophobicity parameters R(M)(0) and C(0) were determined from the regression data of the plots, analogous to reversed-phase chromatography. The chromatographically obtained hydrophobicity parameters were correlated with the calculated log P values. The current results were correlated with the lipophilicity of the studied ACE inhibitors and their metabolites, previously estimated by reversed-phase chromatography.
AB  - Hromatografsko razdvajanje I ponašanje pet ASE inhibitora (inhibitora angio-tenzin-konvertujućeg enzima) I njihova četiri aktivna metabolita ispitivano je metodom normalno-fazne tankoslojne hromatografije na silika-gelu primenom nekoliko jedno- I dvo-komponentnih nevodenih sistema rastvarača. Dobijena je linearna zavisnost između RM-vrednosti I koncentracije etanola u mobilnoj fazi. Na osnovu odgovarajućih regresionih podataka, po analogiji sa reverzno-faznom hromatografijom, izračunati su parametri lipofilnosti 0M R I C0. Hromatografski dobijeni parametri hidrofobnosti korelisani su sa izračunatim log P vrednostima. Takođe, 0M R -vrednosti dobijene u ovom radu korelisane su sa 0M R -vrednostima dobijenim metodom reverzno-fazne tankoslojne hromatografije.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Normal-phase thin-layer chromatography of some angiotensin converting enzyme (ACE) inhibitors and their metabolites
T1  - Normalno-fazna tankoslojna hromatografija nekih ACE inhibitora i njihovih metabolita
VL  - 74
IS  - 6
SP  - 677
EP  - 688
DO  - 10.2298/JSC0906677O
ER  - 

@article{
author = "Odovic, Jadranka and Aleksic, Mirjana and Stojimirovic, Biljana and Milojković-Opsenica, Dušanka and Tešić, Živoslav Lj.",
year = "2009",
abstract = "The separation and chromatographic behaviour of five ACE (angiotensin converting enzyme) inhibitors and their four active metabolites were investigated by normal-phase thin-layer chromatography on silica using several mono- and binary non-aqueous solvent systems. The linear relationship between the R(M) values and the composition 0 of employed mobile phase was obtained. The hydrophobicity parameters R(M)(0) and C(0) were determined from the regression data of the plots, analogous to reversed-phase chromatography. The chromatographically obtained hydrophobicity parameters were correlated with the calculated log P values. The current results were correlated with the lipophilicity of the studied ACE inhibitors and their metabolites, previously estimated by reversed-phase chromatography., Hromatografsko razdvajanje I ponašanje pet ASE inhibitora (inhibitora angio-tenzin-konvertujućeg enzima) I njihova četiri aktivna metabolita ispitivano je metodom normalno-fazne tankoslojne hromatografije na silika-gelu primenom nekoliko jedno- I dvo-komponentnih nevodenih sistema rastvarača. Dobijena je linearna zavisnost između RM-vrednosti I koncentracije etanola u mobilnoj fazi. Na osnovu odgovarajućih regresionih podataka, po analogiji sa reverzno-faznom hromatografijom, izračunati su parametri lipofilnosti 0M R I C0. Hromatografski dobijeni parametri hidrofobnosti korelisani su sa izračunatim log P vrednostima. Takođe, 0M R -vrednosti dobijene u ovom radu korelisane su sa 0M R -vrednostima dobijenim metodom reverzno-fazne tankoslojne hromatografije.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Normal-phase thin-layer chromatography of some angiotensin converting enzyme (ACE) inhibitors and their metabolites, Normalno-fazna tankoslojna hromatografija nekih ACE inhibitora i njihovih metabolita",
volume = "74",
number = "6",
pages = "677-688",
doi = "10.2298/JSC0906677O"
}

Odovic, J., Aleksic, M., Stojimirovic, B., Milojković-Opsenica, D.,& Tešić, Ž. Lj.. (2009). Normal-phase thin-layer chromatography of some angiotensin converting enzyme (ACE) inhibitors and their metabolites. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 74(6), 677-688.
https://doi.org/10.2298/JSC0906677O

Odovic J, Aleksic M, Stojimirovic B, Milojković-Opsenica D, Tešić ŽL. Normal-phase thin-layer chromatography of some angiotensin converting enzyme (ACE) inhibitors and their metabolites. in Journal of the Serbian Chemical Society. 2009;74(6):677-688.
doi:10.2298/JSC0906677O .

Odovic, Jadranka, Aleksic, Mirjana, Stojimirovic, Biljana, Milojković-Opsenica, Dušanka, Tešić, Živoslav Lj., "Normal-phase thin-layer chromatography of some angiotensin converting enzyme (ACE) inhibitors and their metabolites" in Journal of the Serbian Chemical Society, 74, no. 6 (2009):677-688,
https://doi.org/10.2298/JSC0906677O . .

TY  - JOUR
AU  - Tosti, Tomislav
AU  - Rakic, Gordana
AU  - Natić, Maja
AU  - Milojković-Opsenica, Dušanka
AU  - Husinec, Suren
AU  - Savić, Vladimir
AU  - Tešić, Živoslav Lj.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/874
AB  - The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C(18) silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R(M) values and mobile phase composition was established. From results obtained, the lipophilicity R(M)(o) and C(0) were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents
VL  - 22
IS  - 5
SP  - 333
EP  - 343
DO  - 10.1556/JPC.22.2009.5.4
ER  - 

@article{
author = "Tosti, Tomislav and Rakic, Gordana and Natić, Maja and Milojković-Opsenica, Dušanka and Husinec, Suren and Savić, Vladimir and Tešić, Živoslav Lj.",
year = "2009",
abstract = "The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C(18) silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R(M) values and mobile phase composition was established. From results obtained, the lipophilicity R(M)(o) and C(0) were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents",
volume = "22",
number = "5",
pages = "333-343",
doi = "10.1556/JPC.22.2009.5.4"
}

Tosti, T., Rakic, G., Natić, M., Milojković-Opsenica, D., Husinec, S., Savić, V.,& Tešić, Ž. Lj.. (2009). TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Research Inst Medicinal Plants, Budakalasz., 22(5), 333-343.
https://doi.org/10.1556/JPC.22.2009.5.4

Tosti T, Rakic G, Natić M, Milojković-Opsenica D, Husinec S, Savić V, Tešić ŽL. TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2009;22(5):333-343.
doi:10.1556/JPC.22.2009.5.4 .

Tosti, Tomislav, Rakic, Gordana, Natić, Maja, Milojković-Opsenica, Dušanka, Husinec, Suren, Savić, Vladimir, Tešić, Živoslav Lj., "TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 22, no. 5 (2009):333-343,
https://doi.org/10.1556/JPC.22.2009.5.4 . .

TY  - JOUR
AU  - Gligorijević, Nevenka
AU  - Todorović, Tamara
AU  - Radulović, Siniša
AU  - Sladić, Dušan
AU  - Filipović, Nenad R.
AU  - Gođevac, Dejan
AU  - Jeremić, Dejan
AU  - Anđelković, Katarina K.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/625
AB  - New complexes of Pt(II) and Pd(II) with 2-quinolinecarboxaldehyde selenosemicarbazone were synthesized and characterized by elemental analysis, NMR and IR spectroscopy and molar conductivity measurements. The assumed geometry of Pt(II) and Pd(II) complexes was square planar where the ligand was tridentately coordinated via the quinoline and imine nitrogen atoms and the selenium atom. The cytotoxic activity of the new Pt(II) and Pd(II) compounds, as well as of some previously synthesized Cd(II), Zn(II) and Ni(II) complexes with the same or analogous ligand, was tested against a panel of three human cancer cell lines: human cervix carcinoma cells (HeLa), human melanoma cells (FemX) and breast cancer cells (MDA-361). All investigated compounds, except Pt(II) complex, possess a strong dose-dependent cytotoxic activity of the same order of magnitude as cisplatin (CDDP). The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated. (c) 2008 Elsevier Masson SAS. All rights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones
VL  - 44
IS  - 4
SP  - 1623
EP  - 1629
DO  - 10.1016/j.ejmech.2008.07.033
ER  - 

@article{
author = "Gligorijević, Nevenka and Todorović, Tamara and Radulović, Siniša and Sladić, Dušan and Filipović, Nenad R. and Gođevac, Dejan and Jeremić, Dejan and Anđelković, Katarina K.",
year = "2009",
abstract = "New complexes of Pt(II) and Pd(II) with 2-quinolinecarboxaldehyde selenosemicarbazone were synthesized and characterized by elemental analysis, NMR and IR spectroscopy and molar conductivity measurements. The assumed geometry of Pt(II) and Pd(II) complexes was square planar where the ligand was tridentately coordinated via the quinoline and imine nitrogen atoms and the selenium atom. The cytotoxic activity of the new Pt(II) and Pd(II) compounds, as well as of some previously synthesized Cd(II), Zn(II) and Ni(II) complexes with the same or analogous ligand, was tested against a panel of three human cancer cell lines: human cervix carcinoma cells (HeLa), human melanoma cells (FemX) and breast cancer cells (MDA-361). All investigated compounds, except Pt(II) complex, possess a strong dose-dependent cytotoxic activity of the same order of magnitude as cisplatin (CDDP). The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated. (c) 2008 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones",
volume = "44",
number = "4",
pages = "1623-1629",
doi = "10.1016/j.ejmech.2008.07.033"
}

Gligorijević, N., Todorović, T., Radulović, S., Sladić, D., Filipović, N. R., Gođevac, D., Jeremić, D.,& Anđelković, K. K.. (2009). Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 44(4), 1623-1629.
https://doi.org/10.1016/j.ejmech.2008.07.033

Gligorijević N, Todorović T, Radulović S, Sladić D, Filipović NR, Gođevac D, Jeremić D, Anđelković KK. Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones. in European Journal of Medicinal Chemistry. 2009;44(4):1623-1629.
doi:10.1016/j.ejmech.2008.07.033 .

Gligorijević, Nevenka, Todorović, Tamara, Radulović, Siniša, Sladić, Dušan, Filipović, Nenad R., Gođevac, Dejan, Jeremić, Dejan, Anđelković, Katarina K., "Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones" in European Journal of Medicinal Chemistry, 44, no. 4 (2009):1623-1629,
https://doi.org/10.1016/j.ejmech.2008.07.033 . .

TY  - JOUR
AU  - Drazici, Branka
AU  - Popovic, Gordana
AU  - Jelić, Ratomir
AU  - Sladić, Dušan
AU  - Mitić, Dragana
AU  - Anđelković, Katarina K.
AU  - Tešić, Živoslav Lj.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/622
AB  - Acid-base equilibria of Zn(II) and Fe(III) complexes with N',N'(2)-bis-[(1E)-1-(2-pyridyl)ethylidene]ethanedihydrazide (ligand L1) and N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide (ligand L2), i.e., [Fe(L1)Cl(2)(H(2)O)], [Fe(L2)Cl(H(2)O)](2+), [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+), which expressed cytotoxic activity, were investigated in aqueous media. The equilibrium constants were determined potentiometrically at 25 degrees C at a constant ionic strength of 0.10 mol/dm(3) (Na(2)SO(4)). The results showed that at pH  lt  8 both the Fe(III) complexes studied here have three, while [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+) have one and two titratable protons, respectively. Based on the obtained values for the equilibrium constants, protonation schemes of the examined complexes are proposed.
AB  - U ovom radu su proučavane kiselinsko-bazne ravnoteže u vodenim rastvorima kompleksa Zn(II) i Fe(III) sa N',N'2-bis[(1E)-1-(2-piridil)etiliden]etandihidrazidom (ligand L1) i N',N'2-bis[(1E)-1-(2-piridil)etiliden]propandihidrazidom (ligand L2), tj. [Fe(L1)Cl2(H2O)], [Fe(L2)Cl(H2O)]2+, [Zn(L1)(H2O)3]+, [Zn(L2)(H2O)2]2+, koji pokazuju citotoksičnu aktivnost. Ravnotežne konstante su određivane potenciometrijski, na temperaturi 25°C i pri konstantnoj jonskoj jačini 0,10 mol/dm3 Na2SO4. Utvrđeno je da u intervalu pH  lt  8 ispitivani Fe(III) kompleksi imaju tri, [Zn(L1)(H2O)3]+ jedan, a [Zn(L2)(H2O)2]2+ dva protona koji mogu da se titrišu. Na osnovu dobijenih vrednosti za konstante, pretpostavljene su i odgovarajuće protonacione sheme.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid
T1  - Kiselinsko-bazne ravnoteže kompleksa Fe(III) i Zn(II) sa kondenzacionim derivatima 2-acetilpiridina i hidrazida oksalne, odnosno malonske kiseline
VL  - 74
IS  - 3
SP  - 269
EP  - 277
DO  - 10.2298/JSC0903269D
ER  - 

@article{
author = "Drazici, Branka and Popovic, Gordana and Jelić, Ratomir and Sladić, Dušan and Mitić, Dragana and Anđelković, Katarina K. and Tešić, Živoslav Lj.",
year = "2009",
abstract = "Acid-base equilibria of Zn(II) and Fe(III) complexes with N',N'(2)-bis-[(1E)-1-(2-pyridyl)ethylidene]ethanedihydrazide (ligand L1) and N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide (ligand L2), i.e., [Fe(L1)Cl(2)(H(2)O)], [Fe(L2)Cl(H(2)O)](2+), [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+), which expressed cytotoxic activity, were investigated in aqueous media. The equilibrium constants were determined potentiometrically at 25 degrees C at a constant ionic strength of 0.10 mol/dm(3) (Na(2)SO(4)). The results showed that at pH  lt  8 both the Fe(III) complexes studied here have three, while [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+) have one and two titratable protons, respectively. Based on the obtained values for the equilibrium constants, protonation schemes of the examined complexes are proposed., U ovom radu su proučavane kiselinsko-bazne ravnoteže u vodenim rastvorima kompleksa Zn(II) i Fe(III) sa N',N'2-bis[(1E)-1-(2-piridil)etiliden]etandihidrazidom (ligand L1) i N',N'2-bis[(1E)-1-(2-piridil)etiliden]propandihidrazidom (ligand L2), tj. [Fe(L1)Cl2(H2O)], [Fe(L2)Cl(H2O)]2+, [Zn(L1)(H2O)3]+, [Zn(L2)(H2O)2]2+, koji pokazuju citotoksičnu aktivnost. Ravnotežne konstante su određivane potenciometrijski, na temperaturi 25°C i pri konstantnoj jonskoj jačini 0,10 mol/dm3 Na2SO4. Utvrđeno je da u intervalu pH  lt  8 ispitivani Fe(III) kompleksi imaju tri, [Zn(L1)(H2O)3]+ jedan, a [Zn(L2)(H2O)2]2+ dva protona koji mogu da se titrišu. Na osnovu dobijenih vrednosti za konstante, pretpostavljene su i odgovarajuće protonacione sheme.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid, Kiselinsko-bazne ravnoteže kompleksa Fe(III) i Zn(II) sa kondenzacionim derivatima 2-acetilpiridina i hidrazida oksalne, odnosno malonske kiseline",
volume = "74",
number = "3",
pages = "269-277",
doi = "10.2298/JSC0903269D"
}

Drazici, B., Popovic, G., Jelić, R., Sladić, D., Mitić, D., Anđelković, K. K.,& Tešić, Ž. Lj.. (2009). Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 74(3), 269-277.
https://doi.org/10.2298/JSC0903269D

Drazici B, Popovic G, Jelić R, Sladić D, Mitić D, Anđelković KK, Tešić ŽL. Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid. in Journal of the Serbian Chemical Society. 2009;74(3):269-277.
doi:10.2298/JSC0903269D .

Drazici, Branka, Popovic, Gordana, Jelić, Ratomir, Sladić, Dušan, Mitić, Dragana, Anđelković, Katarina K., Tešić, Živoslav Lj., "Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid" in Journal of the Serbian Chemical Society, 74, no. 3 (2009):269-277,
https://doi.org/10.2298/JSC0903269D . .

TY  - JOUR
AU  - Mitić, Dragana
AU  - Milenković, Marina
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
AU  - Miodragović, Zoran
AU  - Anđelković, Katarina K.
AU  - Miodragović Đenana U.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/624
AB  - In this paper the first complexes of M(2+) ions (M(2+) = Zn(2+), Cd(2+) and Co(2+)) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and (1)H, (13)C and (15)N NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans. (C) 2008 Elsevier Masson SAS. All rights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2  - European Journal of Medicinal Chemistry
T1  - Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine
VL  - 44
IS  - 4
SP  - 1537
EP  - 1544
DO  - 10.1016/j.ejmech.2008.07.017
ER  - 

@article{
author = "Mitić, Dragana and Milenković, Marina and Milosavljević, Slobodan M. and Gođevac, Dejan and Miodragović, Zoran and Anđelković, Katarina K. and Miodragović Đenana U.",
year = "2009",
abstract = "In this paper the first complexes of M(2+) ions (M(2+) = Zn(2+), Cd(2+) and Co(2+)) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and (1)H, (13)C and (15)N NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans. (C) 2008 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine",
volume = "44",
number = "4",
pages = "1537-1544",
doi = "10.1016/j.ejmech.2008.07.017"
}

Mitić, D., Milenković, M., Milosavljević, S. M., Gođevac, D., Miodragović, Z., Anđelković, K. K.,& Miodragović Đenana U.. (2009). Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Paris., 44(4), 1537-1544.
https://doi.org/10.1016/j.ejmech.2008.07.017

Mitić D, Milenković M, Milosavljević SM, Gođevac D, Miodragović Z, Anđelković KK, Miodragović Đenana U.. Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. in European Journal of Medicinal Chemistry. 2009;44(4):1537-1544.
doi:10.1016/j.ejmech.2008.07.017 .

Mitić, Dragana, Milenković, Marina, Milosavljević, Slobodan M., Gođevac, Dejan, Miodragović, Zoran, Anđelković, Katarina K., Miodragović Đenana U., "Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine" in European Journal of Medicinal Chemistry, 44, no. 4 (2009):1537-1544,
https://doi.org/10.1016/j.ejmech.2008.07.017 . .