TY  - JOUR
AU  - Stanković, Dalibor
AU  - Ristić, Slavica M.
AU  - Vukadinović, Aleksandar
AU  - Mirković, Marija D.
AU  - Vladimirov, Sandra S.
AU  - Milanović, Zorana
AU  - Radović, Magdalena
AU  - Mijović, Milica
AU  - Stanković, Dalibor
AU  - Sabo, Tibor
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2894
AB  - It was reported that novel O,O′-diethyl-(S, S)-ethylenediamine-N,N′-di-2-(3-cyclohexyl) propanoate dihydrochloride (DE-EDCP) displayed in vitro antiproliferative activity on several human and mouse cancer cell lines, which was comparable to that of the prototypical anticancer drug cisplatin. In order to reveal its toxicity profile, acute and repeated-dose toxicity studies were performed in Naval Medical Research Institute (NMRI) Han mice. The intravenous LD 50 values of DE-EDCP were found to be 95.3 and 101.3 mg/kg body weight in female and male mice, respectively. In the subacute toxicity study, DE-EDCP was administered intravenously at the doses of 15, 25, and 40 mg/kg/day for a period of 28 days. There were no adverse effects on general condition, growth, feed and water consumption, and hematological parameters. There was a significant increase in urea and alanine aminotransferase in female mice and aspartate aminotransferase and alkaline phosphatase in both genders in 40 mg/kg/day dose-treated group. The histopathological changes confined to the liver and kidney, but in other organs were not found. Satellite group revealed that changes in the kidney and liver were less pronounced, suggesting their reversibility. Interactions with DNA could also be of importance for understanding DE-EDCP toxic side effects. Hyperchromic effect obtained with ultraviolet–visible, suggested electrostatic interactions between DE-EDCP and calf thymus DNA. The toxicity testing of DE-EDCP was conducted to predict human outcomes.
PB  - SAGE PUBLICATIONS LTD
T2  - Human and Experimental Toxicology
T1  - Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP
VL  - 38
IS  - 4
SP  - 466
EP  - 481
DO  - 10.1177/0960327118819047
ER  - 

@article{
author = "Stanković, Dalibor and Ristić, Slavica M. and Vukadinović, Aleksandar and Mirković, Marija D. and Vladimirov, Sandra S. and Milanović, Zorana and Radović, Magdalena and Mijović, Milica and Stanković, Dalibor and Sabo, Tibor and Vranješ-Đurić, Sanja and Janković, Drina",
year = "2019",
abstract = "It was reported that novel O,O′-diethyl-(S, S)-ethylenediamine-N,N′-di-2-(3-cyclohexyl) propanoate dihydrochloride (DE-EDCP) displayed in vitro antiproliferative activity on several human and mouse cancer cell lines, which was comparable to that of the prototypical anticancer drug cisplatin. In order to reveal its toxicity profile, acute and repeated-dose toxicity studies were performed in Naval Medical Research Institute (NMRI) Han mice. The intravenous LD 50 values of DE-EDCP were found to be 95.3 and 101.3 mg/kg body weight in female and male mice, respectively. In the subacute toxicity study, DE-EDCP was administered intravenously at the doses of 15, 25, and 40 mg/kg/day for a period of 28 days. There were no adverse effects on general condition, growth, feed and water consumption, and hematological parameters. There was a significant increase in urea and alanine aminotransferase in female mice and aspartate aminotransferase and alkaline phosphatase in both genders in 40 mg/kg/day dose-treated group. The histopathological changes confined to the liver and kidney, but in other organs were not found. Satellite group revealed that changes in the kidney and liver were less pronounced, suggesting their reversibility. Interactions with DNA could also be of importance for understanding DE-EDCP toxic side effects. Hyperchromic effect obtained with ultraviolet–visible, suggested electrostatic interactions between DE-EDCP and calf thymus DNA. The toxicity testing of DE-EDCP was conducted to predict human outcomes.",
publisher = "SAGE PUBLICATIONS LTD",
journal = "Human and Experimental Toxicology",
title = "Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP",
volume = "38",
number = "4",
pages = "466-481",
doi = "10.1177/0960327118819047"
}

Stanković, D., Ristić, S. M., Vukadinović, A., Mirković, M. D., Vladimirov, S. S., Milanović, Z., Radović, M., Mijović, M., Stanković, D., Sabo, T., Vranješ-Đurić, S.,& Janković, D.. (2019). Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP. in Human and Experimental Toxicology
SAGE PUBLICATIONS LTD., 38(4), 466-481.
https://doi.org/10.1177/0960327118819047

Stanković D, Ristić SM, Vukadinović A, Mirković MD, Vladimirov SS, Milanović Z, Radović M, Mijović M, Stanković D, Sabo T, Vranješ-Đurić S, Janković D. Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP. in Human and Experimental Toxicology. 2019;38(4):466-481.
doi:10.1177/0960327118819047 .

Stanković, Dalibor, Ristić, Slavica M., Vukadinović, Aleksandar, Mirković, Marija D., Vladimirov, Sandra S., Milanović, Zorana, Radović, Magdalena, Mijović, Milica, Stanković, Dalibor, Sabo, Tibor, Vranješ-Đurić, Sanja, Janković, Drina, "Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP" in Human and Experimental Toxicology, 38, no. 4 (2019):466-481,
https://doi.org/10.1177/0960327118819047 . .

TY  - JOUR
AU  - Perić, Marko
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Iskrenović, Predrag
AU  - Janković, Drina
AU  - Vranješ-Đurić, Sanja
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2910
AB  - The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.
PB  - The Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications
VL  - 43
IS  - 15
SP  - 5932
EP  - 5939
DO  - 10.1039/c8nj06478d
ER  - 

@article{
author = "Perić, Marko and Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Iskrenović, Predrag and Janković, Drina and Vranješ-Đurić, Sanja",
year = "2019",
abstract = "The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.",
publisher = "The Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications",
volume = "43",
number = "15",
pages = "5932-5939",
doi = "10.1039/c8nj06478d"
}

Perić, M., Radović, M., Mirković, M. D., Nikolić, A. S., Iskrenović, P., Janković, D.,& Vranješ-Đurić, S.. (2019). The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry
The Royal Society of Chemistry., 43(15), 5932-5939.
https://doi.org/10.1039/c8nj06478d

Perić M, Radović M, Mirković MD, Nikolić AS, Iskrenović P, Janković D, Vranješ-Đurić S. The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry. 2019;43(15):5932-5939.
doi:10.1039/c8nj06478d .

Perić, Marko, Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Iskrenović, Predrag, Janković, Drina, Vranješ-Đurić, Sanja, "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications" in New Journal of Chemistry, 43, no. 15 (2019):5932-5939,
https://doi.org/10.1039/c8nj06478d . .

TY  - JOUR
AU  - Perić, Marko
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Iskrenović, Predrag
AU  - Janković, Drina
AU  - Vranješ-Đurić, Sanja
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2911
AB  - The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.
PB  - The Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications
VL  - 43
IS  - 15
SP  - 5932
EP  - 5939
DO  - 10.1039/c8nj06478d
ER  - 

@article{
author = "Perić, Marko and Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Iskrenović, Predrag and Janković, Drina and Vranješ-Đurić, Sanja",
year = "2019",
abstract = "The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.",
publisher = "The Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications",
volume = "43",
number = "15",
pages = "5932-5939",
doi = "10.1039/c8nj06478d"
}

Perić, M., Radović, M., Mirković, M. D., Nikolić, A. S., Iskrenović, P., Janković, D.,& Vranješ-Đurić, S.. (2019). The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry
The Royal Society of Chemistry., 43(15), 5932-5939.
https://doi.org/10.1039/c8nj06478d

Perić M, Radović M, Mirković MD, Nikolić AS, Iskrenović P, Janković D, Vranješ-Đurić S. The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry. 2019;43(15):5932-5939.
doi:10.1039/c8nj06478d .

Perić, Marko, Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Iskrenović, Predrag, Janković, Drina, Vranješ-Đurić, Sanja, "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications" in New Journal of Chemistry, 43, no. 15 (2019):5932-5939,
https://doi.org/10.1039/c8nj06478d . .

TY  - JOUR
AU  - Antić, Bratislav
AU  - Bošković, Marko
AU  - Nikodinović-Runić, Jasmina
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Bozin, Emil S.
AU  - Janković, Drina
AU  - Spasojević, Vojislav
AU  - Vranješ-Đurić, Sanja
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3086
AB  - Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science and Engineering C
T1  - Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles
VL  - 75
SP  - 157
EP  - 164
DO  - 10.1016/j.msec.2017.02.023
ER  - 

@article{
author = "Antić, Bratislav and Bošković, Marko and Nikodinović-Runić, Jasmina and Ming, Yue and Zhang, Hongguo and Bozin, Emil S. and Janković, Drina and Spasojević, Vojislav and Vranješ-Đurić, Sanja",
year = "2017",
abstract = "Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science and Engineering C",
title = "Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles",
volume = "75",
pages = "157-164",
doi = "10.1016/j.msec.2017.02.023"
}

Antić, B., Bošković, M., Nikodinović-Runić, J., Ming, Y., Zhang, H., Bozin, E. S., Janković, D., Spasojević, V.,& Vranješ-Đurić, S.. (2017). Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles. in Materials Science and Engineering C
Elsevier Science Bv, Amsterdam., 75, 157-164.
https://doi.org/10.1016/j.msec.2017.02.023

Antić B, Bošković M, Nikodinović-Runić J, Ming Y, Zhang H, Bozin ES, Janković D, Spasojević V, Vranješ-Đurić S. Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles. in Materials Science and Engineering C. 2017;75:157-164.
doi:10.1016/j.msec.2017.02.023 .

Antić, Bratislav, Bošković, Marko, Nikodinović-Runić, Jasmina, Ming, Yue, Zhang, Hongguo, Bozin, Emil S., Janković, Drina, Spasojević, Vojislav, Vranješ-Đurić, Sanja, "Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles" in Materials Science and Engineering C, 75 (2017):157-164,
https://doi.org/10.1016/j.msec.2017.02.023 . .

TY  - JOUR
AU  - Tadić, Mann
AU  - Kopanja, Lazar
AU  - Panjan, Matjaz
AU  - Kralj, Slavko
AU  - Nikodinović-Runić, Jasmina
AU  - Stojanović, Zoran
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3094
AB  - Hematite core-shell nanoparticles with plate-like morphology were synthesized using a one-step hydrothermal synthesis. An XRPD analysis indicates that the sample consist of single-phase alpha-Fe2O3 nanoparticles. SEM and TEM measurements show that the hematite sample is composed of uniform core-shell nanoplates with 10-20 nm thickness, 80-100 nm landscape dimensions (aspect ratio 5) and 3-4 nm thickness of the surface shells. We used computational methods for the quantitative analysis of the core-shell particle structure and circularity shape descriptor for the quantitative shape analysis of the nanoparticles from TEM micrographs. The calculated results indicated that a percentage of the shell area in the nanoparticle area (share [%]) is significant. The determined values of circularity in the perpendicular and oblique perspective clearly show shape anisotropy of the nanoplates. The magnetic properties revealed the ferromagnetic-like properties at room temperature with high coercivity H-C = 2340 Oe, pointing to the shape and surface effects. These results signify core-shell hematite nanoparticles' for practical applications in magnetic devices. The synthesized hematite plate-like nanoparticles exhibit low cytotoxicity levels on the human lung fibroblasts (MRC5) cell line demonstrating the safe use of these nanoparticles for biomedical applications.
PB  - Elsevier Science Bv, Amsterdam
T2  - Applied Surface Science
T1  - Synthesis of core-shell hematite (α-Fe 2 O 3 ) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity
VL  - 403
SP  - 628
EP  - 634
DO  - 10.1016/j.apsusc.2017.01.115
ER  - 

@article{
author = "Tadić, Mann and Kopanja, Lazar and Panjan, Matjaz and Kralj, Slavko and Nikodinović-Runić, Jasmina and Stojanović, Zoran",
year = "2017",
abstract = "Hematite core-shell nanoparticles with plate-like morphology were synthesized using a one-step hydrothermal synthesis. An XRPD analysis indicates that the sample consist of single-phase alpha-Fe2O3 nanoparticles. SEM and TEM measurements show that the hematite sample is composed of uniform core-shell nanoplates with 10-20 nm thickness, 80-100 nm landscape dimensions (aspect ratio 5) and 3-4 nm thickness of the surface shells. We used computational methods for the quantitative analysis of the core-shell particle structure and circularity shape descriptor for the quantitative shape analysis of the nanoparticles from TEM micrographs. The calculated results indicated that a percentage of the shell area in the nanoparticle area (share [%]) is significant. The determined values of circularity in the perpendicular and oblique perspective clearly show shape anisotropy of the nanoplates. The magnetic properties revealed the ferromagnetic-like properties at room temperature with high coercivity H-C = 2340 Oe, pointing to the shape and surface effects. These results signify core-shell hematite nanoparticles' for practical applications in magnetic devices. The synthesized hematite plate-like nanoparticles exhibit low cytotoxicity levels on the human lung fibroblasts (MRC5) cell line demonstrating the safe use of these nanoparticles for biomedical applications.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Applied Surface Science",
title = "Synthesis of core-shell hematite (α-Fe 2 O 3 ) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity",
volume = "403",
pages = "628-634",
doi = "10.1016/j.apsusc.2017.01.115"
}

Tadić, M., Kopanja, L., Panjan, M., Kralj, S., Nikodinović-Runić, J.,& Stojanović, Z.. (2017). Synthesis of core-shell hematite (α-Fe 2 O 3 ) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity. in Applied Surface Science
Elsevier Science Bv, Amsterdam., 403, 628-634.
https://doi.org/10.1016/j.apsusc.2017.01.115

Tadić M, Kopanja L, Panjan M, Kralj S, Nikodinović-Runić J, Stojanović Z. Synthesis of core-shell hematite (α-Fe 2 O 3 ) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity. in Applied Surface Science. 2017;403:628-634.
doi:10.1016/j.apsusc.2017.01.115 .

Tadić, Mann, Kopanja, Lazar, Panjan, Matjaz, Kralj, Slavko, Nikodinović-Runić, Jasmina, Stojanović, Zoran, "Synthesis of core-shell hematite (α-Fe 2 O 3 ) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity" in Applied Surface Science, 403 (2017):628-634,
https://doi.org/10.1016/j.apsusc.2017.01.115 . .

TY  - JOUR
AU  - Tadić, Mann
AU  - Kopanja, Lazar
AU  - Panjan, Matjaz
AU  - Kralj, Slavko
AU  - Nikodinović-Runić, Jasmina
AU  - Stojanović, Zoran
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2431
AB  - Hematite core-shell nanoparticles with plate-like morphology were synthesized using a one-step hydrothermal synthesis. An XRPD analysis indicates that the sample consist of single-phase alpha-Fe2O3 nanoparticles. SEM and TEM measurements show that the hematite sample is composed of uniform core-shell nanoplates with 10-20 nm thickness, 80-100 nm landscape dimensions (aspect ratio 5) and 3-4 nm thickness of the surface shells. We used computational methods for the quantitative analysis of the core-shell particle structure and circularity shape descriptor for the quantitative shape analysis of the nanoparticles from TEM micrographs. The calculated results indicated that a percentage of the shell area in the nanoparticle area (share [%]) is significant. The determined values of circularity in the perpendicular and oblique perspective clearly show shape anisotropy of the nanoplates. The magnetic properties revealed the ferromagnetic-like properties at room temperature with high coercivity H-C = 2340 Oe, pointing to the shape and surface effects. These results signify core-shell hematite nanoparticles' for practical applications in magnetic devices. The synthesized hematite plate-like nanoparticles exhibit low cytotoxicity levels on the human lung fibroblasts (MRC5) cell line demonstrating the safe use of these nanoparticles for biomedical applications.
PB  - Elsevier Science Bv, Amsterdam
T2  - Applied Surface Science
T1  - Synthesis of core-shell hematite (alpha-Fe2O3) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity
VL  - 403
SP  - 628
EP  - 634
DO  - 10.1016/j.apsusc.2017.01.115
ER  - 

@article{
author = "Tadić, Mann and Kopanja, Lazar and Panjan, Matjaz and Kralj, Slavko and Nikodinović-Runić, Jasmina and Stojanović, Zoran",
year = "2017",
abstract = "Hematite core-shell nanoparticles with plate-like morphology were synthesized using a one-step hydrothermal synthesis. An XRPD analysis indicates that the sample consist of single-phase alpha-Fe2O3 nanoparticles. SEM and TEM measurements show that the hematite sample is composed of uniform core-shell nanoplates with 10-20 nm thickness, 80-100 nm landscape dimensions (aspect ratio 5) and 3-4 nm thickness of the surface shells. We used computational methods for the quantitative analysis of the core-shell particle structure and circularity shape descriptor for the quantitative shape analysis of the nanoparticles from TEM micrographs. The calculated results indicated that a percentage of the shell area in the nanoparticle area (share [%]) is significant. The determined values of circularity in the perpendicular and oblique perspective clearly show shape anisotropy of the nanoplates. The magnetic properties revealed the ferromagnetic-like properties at room temperature with high coercivity H-C = 2340 Oe, pointing to the shape and surface effects. These results signify core-shell hematite nanoparticles' for practical applications in magnetic devices. The synthesized hematite plate-like nanoparticles exhibit low cytotoxicity levels on the human lung fibroblasts (MRC5) cell line demonstrating the safe use of these nanoparticles for biomedical applications.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Applied Surface Science",
title = "Synthesis of core-shell hematite (alpha-Fe2O3) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity",
volume = "403",
pages = "628-634",
doi = "10.1016/j.apsusc.2017.01.115"
}

Tadić, M., Kopanja, L., Panjan, M., Kralj, S., Nikodinović-Runić, J.,& Stojanović, Z.. (2017). Synthesis of core-shell hematite (alpha-Fe2O3) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity. in Applied Surface Science
Elsevier Science Bv, Amsterdam., 403, 628-634.
https://doi.org/10.1016/j.apsusc.2017.01.115

Tadić M, Kopanja L, Panjan M, Kralj S, Nikodinović-Runić J, Stojanović Z. Synthesis of core-shell hematite (alpha-Fe2O3) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity. in Applied Surface Science. 2017;403:628-634.
doi:10.1016/j.apsusc.2017.01.115 .

Tadić, Mann, Kopanja, Lazar, Panjan, Matjaz, Kralj, Slavko, Nikodinović-Runić, Jasmina, Stojanović, Zoran, "Synthesis of core-shell hematite (alpha-Fe2O3) nanoplates: Quantitative analysis of the particle structure and shape, high coercivity and low cytotoxicity" in Applied Surface Science, 403 (2017):628-634,
https://doi.org/10.1016/j.apsusc.2017.01.115 . .

TY  - JOUR
AU  - Šaponjić, Aleksandra
AU  - Šaponjić, Đorđe
AU  - Nikolić, Violeta N.
AU  - Milošević, Maja
AU  - Marinović-Cincović, Milena
AU  - Gyoshev, Stanislav
AU  - Vuković, Marina
AU  - Kokunešoski, Maja
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5225
AB  - Amorphous iron (III) oxide was obtained from clay, using ammonium hydroxide as a precipitating agent. Influence of freeze drying under vacuum, as a drying method, on particle size, chemical composition, and crystallinity of obtained iron (III) oxide powder was investigated. After freeze drying, precipitate was annealed in air at 500 C-o and 900 oC. X-ray diffraction, particle size analysis, scanning electron microscopy, energy dispersive spectrometry, Fourier transform infrared spectroscopy, thermogravimetric and differential thermal analysis were used to characterize obtained iron (III) oxide powder. All of three powders obtained by freeze drying and annealing, have low crystallinity and particles with irregular layered shape. Narrow particle size distribution was given by an average diameter value of around 50 mu m for all observed powders. Iron-bearing materials like a-Fe2O3 and gamma-Fe2O3 are obtained. Differential thermal analysis curve of obtained samples showed endothermic reaction at 620 oC which could be ascribed to phase transition from cubic form gamma- - GT alpha- Fe2O3. Thermal transformations of iron (III) oxide, obtained from clay as a natural source, is suitable to explore in the framework of materials chemistry, and opens the possibility to synthesize materials based on Fe2O3 with specific magnetic behavior.
T2  - Science of Sintering
T1  - Iron (III) Oxide Fabrication From Natural Clay With Reference to Phase Transformation gamma- - GT alpha- Fe2O3
VL  - 49
IS  - 2
SP  - 197
EP  - 205
DO  - 10.2298/SOS1702197S
ER  - 

@article{
author = "Šaponjić, Aleksandra and Šaponjić, Đorđe and Nikolić, Violeta N. and Milošević, Maja and Marinović-Cincović, Milena and Gyoshev, Stanislav and Vuković, Marina and Kokunešoski, Maja",
year = "2017",
abstract = "Amorphous iron (III) oxide was obtained from clay, using ammonium hydroxide as a precipitating agent. Influence of freeze drying under vacuum, as a drying method, on particle size, chemical composition, and crystallinity of obtained iron (III) oxide powder was investigated. After freeze drying, precipitate was annealed in air at 500 C-o and 900 oC. X-ray diffraction, particle size analysis, scanning electron microscopy, energy dispersive spectrometry, Fourier transform infrared spectroscopy, thermogravimetric and differential thermal analysis were used to characterize obtained iron (III) oxide powder. All of three powders obtained by freeze drying and annealing, have low crystallinity and particles with irregular layered shape. Narrow particle size distribution was given by an average diameter value of around 50 mu m for all observed powders. Iron-bearing materials like a-Fe2O3 and gamma-Fe2O3 are obtained. Differential thermal analysis curve of obtained samples showed endothermic reaction at 620 oC which could be ascribed to phase transition from cubic form gamma- - GT alpha- Fe2O3. Thermal transformations of iron (III) oxide, obtained from clay as a natural source, is suitable to explore in the framework of materials chemistry, and opens the possibility to synthesize materials based on Fe2O3 with specific magnetic behavior.",
journal = "Science of Sintering",
title = "Iron (III) Oxide Fabrication From Natural Clay With Reference to Phase Transformation gamma- - GT alpha- Fe2O3",
volume = "49",
number = "2",
pages = "197-205",
doi = "10.2298/SOS1702197S"
}

Šaponjić, A., Šaponjić, Đ., Nikolić, V. N., Milošević, M., Marinović-Cincović, M., Gyoshev, S., Vuković, M.,& Kokunešoski, M.. (2017). Iron (III) Oxide Fabrication From Natural Clay With Reference to Phase Transformation gamma- - GT alpha- Fe2O3. in Science of Sintering, 49(2), 197-205.
https://doi.org/10.2298/SOS1702197S

Šaponjić A, Šaponjić Đ, Nikolić VN, Milošević M, Marinović-Cincović M, Gyoshev S, Vuković M, Kokunešoski M. Iron (III) Oxide Fabrication From Natural Clay With Reference to Phase Transformation gamma- - GT alpha- Fe2O3. in Science of Sintering. 2017;49(2):197-205.
doi:10.2298/SOS1702197S .

Šaponjić, Aleksandra, Šaponjić, Đorđe, Nikolić, Violeta N., Milošević, Maja, Marinović-Cincović, Milena, Gyoshev, Stanislav, Vuković, Marina, Kokunešoski, Maja, "Iron (III) Oxide Fabrication From Natural Clay With Reference to Phase Transformation gamma- - GT alpha- Fe2O3" in Science of Sintering, 49, no. 2 (2017):197-205,
https://doi.org/10.2298/SOS1702197S . .

TY  - JOUR
AU  - Antić, Bratislav
AU  - Bošković, Marko
AU  - Nikodinović-Runić, Jasmina
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Bozin, Emil S.
AU  - Janković, Drina
AU  - Spasojević, Vojislav
AU  - Vranješ-Đurić, Sanja
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2453
AB  - Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science and Engineering. C: Materials for Biological Applications
T1  - Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles
VL  - 75
SP  - 157
EP  - 164
DO  - 10.1016/j.msec.2017.02.023
ER  - 

@article{
author = "Antić, Bratislav and Bošković, Marko and Nikodinović-Runić, Jasmina and Ming, Yue and Zhang, Hongguo and Bozin, Emil S. and Janković, Drina and Spasojević, Vojislav and Vranješ-Đurić, Sanja",
year = "2017",
abstract = "Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science and Engineering. C: Materials for Biological Applications",
title = "Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles",
volume = "75",
pages = "157-164",
doi = "10.1016/j.msec.2017.02.023"
}

Antić, B., Bošković, M., Nikodinović-Runić, J., Ming, Y., Zhang, H., Bozin, E. S., Janković, D., Spasojević, V.,& Vranješ-Đurić, S.. (2017). Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles. in Materials Science and Engineering. C: Materials for Biological Applications
Elsevier Science Bv, Amsterdam., 75, 157-164.
https://doi.org/10.1016/j.msec.2017.02.023

Antić B, Bošković M, Nikodinović-Runić J, Ming Y, Zhang H, Bozin ES, Janković D, Spasojević V, Vranješ-Đurić S. Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles. in Materials Science and Engineering. C: Materials for Biological Applications. 2017;75:157-164.
doi:10.1016/j.msec.2017.02.023 .

Antić, Bratislav, Bošković, Marko, Nikodinović-Runić, Jasmina, Ming, Yue, Zhang, Hongguo, Bozin, Emil S., Janković, Drina, Spasojević, Vojislav, Vranješ-Đurić, Sanja, "Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles" in Materials Science and Engineering. C: Materials for Biological Applications, 75 (2017):157-164,
https://doi.org/10.1016/j.msec.2017.02.023 . .

TY  - JOUR
AU  - Lakić, Mladen
AU  - Sabo, Ljubica
AU  - Ristić, Slavica
AU  - Savić, Aleksandar
AU  - Petričević, Saša
AU  - Nikolić, Nadežda
AU  - Vukadinović, Aleksandar
AU  - Janković, Drina
AU  - Sabo, Tibor
AU  - Vranješ-Đurić, Sanja
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2045
AB  - The extensive development of radiopharmaceuticals towards early tumour detection and treatment has increased the demand for new ligands with higher tumour selectivity. Research has been done on the potential of the novel O,O'-diethylethylenediamine-N,N'-di-3-propanoate (L) ligand as a radionuclide vehicle for tumour targeting. Under alkaline conditions, L hydrolyses and produces half ester ligand (L') and diacid ligand (L"), with characteristic donor atom array N, N, O. Ligand L was successfully labelled with Tc-99m at pH=9 by coordination with the octahedral fac-[Tc-99m(CO)(3)(H2O)(3)](+) intermediate, forming the main radioproduct fac-[(TcL)-Tc-99m'(CO)(3)] (Tc1). The Tc-99m complex showed a low lipophilic character (log P = 0.48) and low binding affinity to human serum albumin (2.51 +/- 0.48%). In vitro stability studies in saline and human plasma, as well as challenge studies with cysteine and histidine, revealed high stability of the complex during 24 h. Biodistribution studies of Tc1 in female C57BL/6 mice bearing B16/F1 melanoma metastases showed significant tumour uptake: 9.81 +/- 1.19% ID g(-1) in the liver, 5.87 +/- 0.54% ID g(-1) in the lungs and 3.17 +/- 0.33% ID g(-1) in the ovary at 30 min post-injection. Favourable physicochemical properties, satisfactory in vitro/in vivo stability and biodistribution profile in the experimental metastatic melanoma model indicate the possible application of the radiolabelled ligand in tumour diagnosis. Copyright (C) 2015 John Wiley & Sons, Ltd.
PB  - Wiley, Hoboken
T2  - Applied Organometallic Chemistry
T1  - Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent
VL  - 30
IS  - 2
SP  - 81
EP  - 88
DO  - 10.1002/aoc.3401
ER  - 

@article{
author = "Lakić, Mladen and Sabo, Ljubica and Ristić, Slavica and Savić, Aleksandar and Petričević, Saša and Nikolić, Nadežda and Vukadinović, Aleksandar and Janković, Drina and Sabo, Tibor and Vranješ-Đurić, Sanja",
year = "2016",
abstract = "The extensive development of radiopharmaceuticals towards early tumour detection and treatment has increased the demand for new ligands with higher tumour selectivity. Research has been done on the potential of the novel O,O'-diethylethylenediamine-N,N'-di-3-propanoate (L) ligand as a radionuclide vehicle for tumour targeting. Under alkaline conditions, L hydrolyses and produces half ester ligand (L') and diacid ligand (L"), with characteristic donor atom array N, N, O. Ligand L was successfully labelled with Tc-99m at pH=9 by coordination with the octahedral fac-[Tc-99m(CO)(3)(H2O)(3)](+) intermediate, forming the main radioproduct fac-[(TcL)-Tc-99m'(CO)(3)] (Tc1). The Tc-99m complex showed a low lipophilic character (log P = 0.48) and low binding affinity to human serum albumin (2.51 +/- 0.48%). In vitro stability studies in saline and human plasma, as well as challenge studies with cysteine and histidine, revealed high stability of the complex during 24 h. Biodistribution studies of Tc1 in female C57BL/6 mice bearing B16/F1 melanoma metastases showed significant tumour uptake: 9.81 +/- 1.19% ID g(-1) in the liver, 5.87 +/- 0.54% ID g(-1) in the lungs and 3.17 +/- 0.33% ID g(-1) in the ovary at 30 min post-injection. Favourable physicochemical properties, satisfactory in vitro/in vivo stability and biodistribution profile in the experimental metastatic melanoma model indicate the possible application of the radiolabelled ligand in tumour diagnosis. Copyright (C) 2015 John Wiley & Sons, Ltd.",
publisher = "Wiley, Hoboken",
journal = "Applied Organometallic Chemistry",
title = "Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent",
volume = "30",
number = "2",
pages = "81-88",
doi = "10.1002/aoc.3401"
}

Lakić, M., Sabo, L., Ristić, S., Savić, A., Petričević, S., Nikolić, N., Vukadinović, A., Janković, D., Sabo, T.,& Vranješ-Đurić, S.. (2016). Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent. in Applied Organometallic Chemistry
Wiley, Hoboken., 30(2), 81-88.
https://doi.org/10.1002/aoc.3401

Lakić M, Sabo L, Ristić S, Savić A, Petričević S, Nikolić N, Vukadinović A, Janković D, Sabo T, Vranješ-Đurić S. Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent. in Applied Organometallic Chemistry. 2016;30(2):81-88.
doi:10.1002/aoc.3401 .

Lakić, Mladen, Sabo, Ljubica, Ristić, Slavica, Savić, Aleksandar, Petričević, Saša, Nikolić, Nadežda, Vukadinović, Aleksandar, Janković, Drina, Sabo, Tibor, Vranješ-Đurić, Sanja, "Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent" in Applied Organometallic Chemistry, 30, no. 2 (2016):81-88,
https://doi.org/10.1002/aoc.3401 . .

TY  - JOUR
AU  - Nikolić, Aleksandar S.
AU  - Bošković, Marko
AU  - Spasojević, Vojislav
AU  - Jancar, B.
AU  - Antić, Bratislav
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1760
AB  - Magnetic nanocomposites can show enhanced properties compared to their single phase counterparts. Novel soft ferrite Fe3O4/soft ferrite MnFe2O4 nanocomposite, as well as pure MnFe2O4 and Fe3O4 for the sake of comparison, were synthesized by co-precipitation method. The spinel type of structure (space group Fd (3) over barm) of the samples was confirmed by XRPD and SAED. Samples are composed of spherical particles with size in the range 5-15 nm. Nanocomposite (92 wt%) MnFe2O4/(8 wt%) Fe3O4 exert single phase like magnetic behavior. Saturation magnetization (M-S) of Fe3O4/MnFe2O4 is 26% greater than M-S of MnFe2O4 and even 50% than M-S of Fe3O4. At the same time coercivity field of the nanocomposite is twice less value (H-C=180 Oe) than in binary ferrites (H-C=360 Oe). Magnetization enhancement and softening in Magnetite/Mn-ferrite is discussed related to particle interactions among two different ferrites and intrinsic properties of nanoparticles. Tailoring phase ratio and synthesis conditions can be a tool for tuning magnetic properties of nanocomposites. (C) 2014 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Letters
T1  - Magnetite/Mn-ferrite nanocomposite with improved magnetic properties
VL  - 120
SP  - 86
EP  - 89
DO  - 10.1016/j.matlet.2014.01.023
ER  - 

@article{
author = "Nikolić, Aleksandar S. and Bošković, Marko and Spasojević, Vojislav and Jancar, B. and Antić, Bratislav",
year = "2014",
abstract = "Magnetic nanocomposites can show enhanced properties compared to their single phase counterparts. Novel soft ferrite Fe3O4/soft ferrite MnFe2O4 nanocomposite, as well as pure MnFe2O4 and Fe3O4 for the sake of comparison, were synthesized by co-precipitation method. The spinel type of structure (space group Fd (3) over barm) of the samples was confirmed by XRPD and SAED. Samples are composed of spherical particles with size in the range 5-15 nm. Nanocomposite (92 wt%) MnFe2O4/(8 wt%) Fe3O4 exert single phase like magnetic behavior. Saturation magnetization (M-S) of Fe3O4/MnFe2O4 is 26% greater than M-S of MnFe2O4 and even 50% than M-S of Fe3O4. At the same time coercivity field of the nanocomposite is twice less value (H-C=180 Oe) than in binary ferrites (H-C=360 Oe). Magnetization enhancement and softening in Magnetite/Mn-ferrite is discussed related to particle interactions among two different ferrites and intrinsic properties of nanoparticles. Tailoring phase ratio and synthesis conditions can be a tool for tuning magnetic properties of nanocomposites. (C) 2014 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Letters",
title = "Magnetite/Mn-ferrite nanocomposite with improved magnetic properties",
volume = "120",
pages = "86-89",
doi = "10.1016/j.matlet.2014.01.023"
}

Nikolić, A. S., Bošković, M., Spasojević, V., Jancar, B.,& Antić, B.. (2014). Magnetite/Mn-ferrite nanocomposite with improved magnetic properties. in Materials Letters
Elsevier Science Bv, Amsterdam., 120, 86-89.
https://doi.org/10.1016/j.matlet.2014.01.023

Nikolić AS, Bošković M, Spasojević V, Jancar B, Antić B. Magnetite/Mn-ferrite nanocomposite with improved magnetic properties. in Materials Letters. 2014;120:86-89.
doi:10.1016/j.matlet.2014.01.023 .

Nikolić, Aleksandar S., Bošković, Marko, Spasojević, Vojislav, Jancar, B., Antić, Bratislav, "Magnetite/Mn-ferrite nanocomposite with improved magnetic properties" in Materials Letters, 120 (2014):86-89,
https://doi.org/10.1016/j.matlet.2014.01.023 . .

TY  - JOUR
AU  - Nikolić, Aleksandar S.
AU  - Bošković, Marko
AU  - Fabian, M.
AU  - Bozanic, D. K.
AU  - Vučinić-Vasić, M.
AU  - Kremenović, Aleksandar
AU  - Antić, Bratislav
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1459
AB  - Herein a comparative study of five nanocrystalline cerium oxides (CeO2-delta) synthesised by different methods and calcined at 500 degrees C is reported. XRPD analysis showed that stoichiometry parameter delta, crystallite size/strain and lattice constant were only slightly affected by the method utilized. All ceria nanoparticles are nearly spherical in shape with faceted morphology, free of defects and with a relatively uniform size distribution. The average microstrain was found to be approximately 10 times higher than that of bulk counterpart. The absorption edge of nanocrystalline materials was shifted towards a higher wavelengths (red shift) in comparison with bulk counterpart, and band gap values were in the range 2.7-3.24 eV (3.33 eV for bulk counterpart).
PB  - Amer Scientific Publishers, Valencia
T2  - Journal of Nanoscience and Nanotechnology
T1  - Comparative Structural and Optical Properties of Different Ceria Nanoparticles
VL  - 13
IS  - 10
SP  - 6787
EP  - 6792
DO  - 10.1166/jnn.2013.7774
ER  - 

@article{
author = "Nikolić, Aleksandar S. and Bošković, Marko and Fabian, M. and Bozanic, D. K. and Vučinić-Vasić, M. and Kremenović, Aleksandar and Antić, Bratislav",
year = "2013",
abstract = "Herein a comparative study of five nanocrystalline cerium oxides (CeO2-delta) synthesised by different methods and calcined at 500 degrees C is reported. XRPD analysis showed that stoichiometry parameter delta, crystallite size/strain and lattice constant were only slightly affected by the method utilized. All ceria nanoparticles are nearly spherical in shape with faceted morphology, free of defects and with a relatively uniform size distribution. The average microstrain was found to be approximately 10 times higher than that of bulk counterpart. The absorption edge of nanocrystalline materials was shifted towards a higher wavelengths (red shift) in comparison with bulk counterpart, and band gap values were in the range 2.7-3.24 eV (3.33 eV for bulk counterpart).",
publisher = "Amer Scientific Publishers, Valencia",
journal = "Journal of Nanoscience and Nanotechnology",
title = "Comparative Structural and Optical Properties of Different Ceria Nanoparticles",
volume = "13",
number = "10",
pages = "6787-6792",
doi = "10.1166/jnn.2013.7774"
}

Nikolić, A. S., Bošković, M., Fabian, M., Bozanic, D. K., Vučinić-Vasić, M., Kremenović, A.,& Antić, B.. (2013). Comparative Structural and Optical Properties of Different Ceria Nanoparticles. in Journal of Nanoscience and Nanotechnology
Amer Scientific Publishers, Valencia., 13(10), 6787-6792.
https://doi.org/10.1166/jnn.2013.7774

Nikolić AS, Bošković M, Fabian M, Bozanic DK, Vučinić-Vasić M, Kremenović A, Antić B. Comparative Structural and Optical Properties of Different Ceria Nanoparticles. in Journal of Nanoscience and Nanotechnology. 2013;13(10):6787-6792.
doi:10.1166/jnn.2013.7774 .

Nikolić, Aleksandar S., Bošković, Marko, Fabian, M., Bozanic, D. K., Vučinić-Vasić, M., Kremenović, Aleksandar, Antić, Bratislav, "Comparative Structural and Optical Properties of Different Ceria Nanoparticles" in Journal of Nanoscience and Nanotechnology, 13, no. 10 (2013):6787-6792,
https://doi.org/10.1166/jnn.2013.7774 . .

TY  - JOUR
AU  - Nikolić, Aleksandar S.
AU  - Jovic, N.
AU  - Rogan, J.
AU  - Kremenović, Aleksandar
AU  - Ristic, M.
AU  - Meden, A.
AU  - Antić, Bratislav
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1363
AB  - Different synthesis methods for the preparation of nanocrystalline nickel ferrites are reported: the thermal decomposition of precursors, made of: (i) metal-nitrate salts with carboxylic acids (citric, malonic and tartaric), and (ii) metal-nitrate salts and polyethylene glycol (PEG), in the presence of potassium chloride as a capping agent. The as-prepared gel precursors were characterized by TGA/DTA, while the samples obtained after annealing at 450 degrees C were investigated by FTIR, FESEM, XRD and Mossbauer spectroscopy. Regardless of the type of carboxylic acid used, nanocrystallites prepared by (i) method are similar in size (11-16 nm), while the method (ii) gives crystallites similar to 33 nm in size with negligible microstrain. The differences in the lattice parameter, ranging from 8.3369(2) to 8.3574(2) angstrom, result from cation distribution, nonstoichiometry and structural imperfections in the nickel ferrite nanoparticles. The Mossbauer spectra analysis indicates existence of large distortions of tetrahedral and octahedral sites in these spinel compounds. (C) 2013 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
PB  - Elsevier Sci Ltd, Oxford
T2  - Ceramics International
T1  - Carboxylic acids and polyethylene glycol assisted synthesis of nanocrystalline nickel ferrites
VL  - 39
IS  - 6
SP  - 6681
EP  - 6688
DO  - 10.1016/j.ceramint.2013.01.106
ER  - 

@article{
author = "Nikolić, Aleksandar S. and Jovic, N. and Rogan, J. and Kremenović, Aleksandar and Ristic, M. and Meden, A. and Antić, Bratislav",
year = "2013",
abstract = "Different synthesis methods for the preparation of nanocrystalline nickel ferrites are reported: the thermal decomposition of precursors, made of: (i) metal-nitrate salts with carboxylic acids (citric, malonic and tartaric), and (ii) metal-nitrate salts and polyethylene glycol (PEG), in the presence of potassium chloride as a capping agent. The as-prepared gel precursors were characterized by TGA/DTA, while the samples obtained after annealing at 450 degrees C were investigated by FTIR, FESEM, XRD and Mossbauer spectroscopy. Regardless of the type of carboxylic acid used, nanocrystallites prepared by (i) method are similar in size (11-16 nm), while the method (ii) gives crystallites similar to 33 nm in size with negligible microstrain. The differences in the lattice parameter, ranging from 8.3369(2) to 8.3574(2) angstrom, result from cation distribution, nonstoichiometry and structural imperfections in the nickel ferrite nanoparticles. The Mossbauer spectra analysis indicates existence of large distortions of tetrahedral and octahedral sites in these spinel compounds. (C) 2013 Elsevier Ltd and Techna Group S.r.l. All rights reserved.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Ceramics International",
title = "Carboxylic acids and polyethylene glycol assisted synthesis of nanocrystalline nickel ferrites",
volume = "39",
number = "6",
pages = "6681-6688",
doi = "10.1016/j.ceramint.2013.01.106"
}

Nikolić, A. S., Jovic, N., Rogan, J., Kremenović, A., Ristic, M., Meden, A.,& Antić, B.. (2013). Carboxylic acids and polyethylene glycol assisted synthesis of nanocrystalline nickel ferrites. in Ceramics International
Elsevier Sci Ltd, Oxford., 39(6), 6681-6688.
https://doi.org/10.1016/j.ceramint.2013.01.106

Nikolić AS, Jovic N, Rogan J, Kremenović A, Ristic M, Meden A, Antić B. Carboxylic acids and polyethylene glycol assisted synthesis of nanocrystalline nickel ferrites. in Ceramics International. 2013;39(6):6681-6688.
doi:10.1016/j.ceramint.2013.01.106 .

Nikolić, Aleksandar S., Jovic, N., Rogan, J., Kremenović, Aleksandar, Ristic, M., Meden, A., Antić, Bratislav, "Carboxylic acids and polyethylene glycol assisted synthesis of nanocrystalline nickel ferrites" in Ceramics International, 39, no. 6 (2013):6681-6688,
https://doi.org/10.1016/j.ceramint.2013.01.106 . .

TY  - JOUR
AU  - Antić, Bratislav
AU  - Kremenović, Aleksandar
AU  - Jovic, N.
AU  - Pavlović, Miodrag B.
AU  - Jovalekic, C.
AU  - Nikolić, Aleksandar S.
AU  - Goya, G. F.
AU  - Weidenthaler, C.
PY  - 2012
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1285
AB  - We present a study of the structural and magnetic properties of (Mn,Fe)(3-delta)O-4 nanoparticles synthesized by soft mechanochemistry using Mn(OH)(2) x 2 H2O and Fe(OH)(3) powders as starting compounds. The resulting nanoparticles with a composition of the (Mn,Fe)(3-delta)O-4 type are found to have a core/shell structure with different Mn/Fe ratios in the core and at the surface. XPS analysis points to valences of +2, +3, and +4 for Mn and +3 for Fe at the particle surface. Combined results of XRPD, Mossbauer spectroscopy, and EDX analysis suggest that there is a deviation from stoichiometry in the nanoparticle core compared to the shell, accompanied by creation of cation polyvalence and vacancies. The value of saturation magnetization, M-S, of 73.5 emu/g at room temperature, is among the highest reported so far among nanocrystalline ferrite systems of similar composition. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3700228]
PB  - Amer Inst Physics, Melville
T2  - Journal of Applied Physics
T1  - Magnetization enhancement and cation valences in nonstoichiometric (Mn,Fe)(3-delta)O-4 nanoparticles
VL  - 111
IS  - 7
DO  - 10.1063/1.3700228
ER  - 

@article{
author = "Antić, Bratislav and Kremenović, Aleksandar and Jovic, N. and Pavlović, Miodrag B. and Jovalekic, C. and Nikolić, Aleksandar S. and Goya, G. F. and Weidenthaler, C.",
year = "2012",
abstract = "We present a study of the structural and magnetic properties of (Mn,Fe)(3-delta)O-4 nanoparticles synthesized by soft mechanochemistry using Mn(OH)(2) x 2 H2O and Fe(OH)(3) powders as starting compounds. The resulting nanoparticles with a composition of the (Mn,Fe)(3-delta)O-4 type are found to have a core/shell structure with different Mn/Fe ratios in the core and at the surface. XPS analysis points to valences of +2, +3, and +4 for Mn and +3 for Fe at the particle surface. Combined results of XRPD, Mossbauer spectroscopy, and EDX analysis suggest that there is a deviation from stoichiometry in the nanoparticle core compared to the shell, accompanied by creation of cation polyvalence and vacancies. The value of saturation magnetization, M-S, of 73.5 emu/g at room temperature, is among the highest reported so far among nanocrystalline ferrite systems of similar composition. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3700228]",
publisher = "Amer Inst Physics, Melville",
journal = "Journal of Applied Physics",
title = "Magnetization enhancement and cation valences in nonstoichiometric (Mn,Fe)(3-delta)O-4 nanoparticles",
volume = "111",
number = "7",
doi = "10.1063/1.3700228"
}

Antić, B., Kremenović, A., Jovic, N., Pavlović, M. B., Jovalekic, C., Nikolić, A. S., Goya, G. F.,& Weidenthaler, C.. (2012). Magnetization enhancement and cation valences in nonstoichiometric (Mn,Fe)(3-delta)O-4 nanoparticles. in Journal of Applied Physics
Amer Inst Physics, Melville., 111(7).
https://doi.org/10.1063/1.3700228

Antić B, Kremenović A, Jovic N, Pavlović MB, Jovalekic C, Nikolić AS, Goya GF, Weidenthaler C. Magnetization enhancement and cation valences in nonstoichiometric (Mn,Fe)(3-delta)O-4 nanoparticles. in Journal of Applied Physics. 2012;111(7).
doi:10.1063/1.3700228 .

Antić, Bratislav, Kremenović, Aleksandar, Jovic, N., Pavlović, Miodrag B., Jovalekic, C., Nikolić, Aleksandar S., Goya, G. F., Weidenthaler, C., "Magnetization enhancement and cation valences in nonstoichiometric (Mn,Fe)(3-delta)O-4 nanoparticles" in Journal of Applied Physics, 111, no. 7 (2012),
https://doi.org/10.1063/1.3700228 . .

TY  - JOUR
AU  - Kremenović, Aleksandar
AU  - Bozanic, D. K.
AU  - Welsch, A. -M.
AU  - Jancar, B.
AU  - Nikolić, Aleksandar S.
AU  - Bošković, Marko
AU  - Colomban, Ph.
AU  - Fabian, Martin
AU  - Antić, Bratislav
PY  - 2012
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1603
AB  - The 5-10 nnn Ce1-XEuXO2-delta (0  lt = x  lt = 0.30) nanoparticles with fluorite structure were synthesized by thermal decomposition of Eu- and Ce-2,4-pentanedione complexes mixtures. X-ray line broadening analysis of mixed samples Ce1-XEuXO2-delta (0.05  lt = x  lt = 0.30) showed that the crystallite size was lower and root mean square strain higher than in pure ceria. However, within mixed samples Ce1-XEuXO2-delta (0.05  lt = x  lt = 0.30) crystallite size and root mean square strain were independent of Eu3+ concentration. Raman spectroscopy results indicated that europium ions yield disorder by breaking the phonon propagation and therefore making the non-centre Brillouin zone modes Raman active. The absorption bands in the spectra of mixed oxides were blue-shifted in comparison to pure CeO2-delta nanopowder. The samples show red emission typical for Eu ions. The biggest photoluminescent intensity was observed for the highest Eu3+ concentration (x = 0.30) and further enhanced with the increase in crystallinity.
PB  - Amer Scientific Publishers, Valencia
T2  - Journal of Nanoscience and Nanotechnology
T1  - Effects of Eu3+ Concentration on Structural, Optical and Vibrational Properties of Multifunctional Ce1-X,EuXO2-delta Nanoparticles Synthesized by Thermolysis of 2,4-Pentanedione Complexes
VL  - 12
IS  - 12
SP  - 8893
EP  - 8899
DO  - 10.1166/jnn.2012.6797
ER  - 

@article{
author = "Kremenović, Aleksandar and Bozanic, D. K. and Welsch, A. -M. and Jancar, B. and Nikolić, Aleksandar S. and Bošković, Marko and Colomban, Ph. and Fabian, Martin and Antić, Bratislav",
year = "2012",
abstract = "The 5-10 nnn Ce1-XEuXO2-delta (0  lt = x  lt = 0.30) nanoparticles with fluorite structure were synthesized by thermal decomposition of Eu- and Ce-2,4-pentanedione complexes mixtures. X-ray line broadening analysis of mixed samples Ce1-XEuXO2-delta (0.05  lt = x  lt = 0.30) showed that the crystallite size was lower and root mean square strain higher than in pure ceria. However, within mixed samples Ce1-XEuXO2-delta (0.05  lt = x  lt = 0.30) crystallite size and root mean square strain were independent of Eu3+ concentration. Raman spectroscopy results indicated that europium ions yield disorder by breaking the phonon propagation and therefore making the non-centre Brillouin zone modes Raman active. The absorption bands in the spectra of mixed oxides were blue-shifted in comparison to pure CeO2-delta nanopowder. The samples show red emission typical for Eu ions. The biggest photoluminescent intensity was observed for the highest Eu3+ concentration (x = 0.30) and further enhanced with the increase in crystallinity.",
publisher = "Amer Scientific Publishers, Valencia",
journal = "Journal of Nanoscience and Nanotechnology",
title = "Effects of Eu3+ Concentration on Structural, Optical and Vibrational Properties of Multifunctional Ce1-X,EuXO2-delta Nanoparticles Synthesized by Thermolysis of 2,4-Pentanedione Complexes",
volume = "12",
number = "12",
pages = "8893-8899",
doi = "10.1166/jnn.2012.6797"
}

Kremenović, A., Bozanic, D. K., Welsch, A. -M., Jancar, B., Nikolić, A. S., Bošković, M., Colomban, Ph., Fabian, M.,& Antić, B.. (2012). Effects of Eu3+ Concentration on Structural, Optical and Vibrational Properties of Multifunctional Ce1-X,EuXO2-delta Nanoparticles Synthesized by Thermolysis of 2,4-Pentanedione Complexes. in Journal of Nanoscience and Nanotechnology
Amer Scientific Publishers, Valencia., 12(12), 8893-8899.
https://doi.org/10.1166/jnn.2012.6797

Kremenović A, Bozanic DK, Welsch A-, Jancar B, Nikolić AS, Bošković M, Colomban P, Fabian M, Antić B. Effects of Eu3+ Concentration on Structural, Optical and Vibrational Properties of Multifunctional Ce1-X,EuXO2-delta Nanoparticles Synthesized by Thermolysis of 2,4-Pentanedione Complexes. in Journal of Nanoscience and Nanotechnology. 2012;12(12):8893-8899.
doi:10.1166/jnn.2012.6797 .

Kremenović, Aleksandar, Bozanic, D. K., Welsch, A. -M., Jancar, B., Nikolić, Aleksandar S., Bošković, Marko, Colomban, Ph., Fabian, Martin, Antić, Bratislav, "Effects of Eu3+ Concentration on Structural, Optical and Vibrational Properties of Multifunctional Ce1-X,EuXO2-delta Nanoparticles Synthesized by Thermolysis of 2,4-Pentanedione Complexes" in Journal of Nanoscience and Nanotechnology, 12, no. 12 (2012):8893-8899,
https://doi.org/10.1166/jnn.2012.6797 . .