TY  - JOUR
AU  - Smiljanić, Katarina
AU  - Prodić, Ivana
AU  - Trifunović, Sara
AU  - Krstić-Ristivojević, Maja
AU  - Aćimović, Milica G.
AU  - Stanković Jeremić, Jovana
AU  - Lončar, Biljana
AU  - Tešević, Vele
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6203
AB  - As byproducts of essential oil distillation, hydrolates are used in natural cosmetics/biomedicine due to their beneficial skin effects. However, data on their safety with relevant biological targets, such as human skin cells, are scarce. Therefore, we have tested nine hydrolates from the Lamiaceae family with skin fibroblasts that are responsible for extracellular collagenous matrix builds. Thyme, oregano, and winter savoury hydrolates showed several times higher total phenolics, which correlated strongly with their radical scavenging and antioxidative capacity; there was no correlation between their viability profiles and the reducing sugar levels. No proteins/peptides were detected. All hydrolates appeared safe for prolonged skin exposure except for 10-fold diluted lavender, which showed cytotoxicity (~20%), as well as rosemary and lavandin (~10%) using viability, DNA synthesis, and cell count testing. Clary sage, oregano, lemon balm, and thyme hydrolates (10-fold diluted) increased fibroblast viability and/or proliferation by 10–30% compared with the control, while their viability remained unaffected by Mentha and winter savoury. In line with the STITCH database, increased viability could be attributed to thymol presence in oregano and thyme hydrolates in lemon balm, which is most likely attributable to neral and geranial. The proliferative effect of clary sage could be supported by alpha-terpineol, not linalool. The major volatile organic compounds (VOCs) associated with cytotoxic effects on fibroblasts were borneol, 1,8-cineole, and terpinene-4-ol. Further research with pure compounds is warranted to confirm the roles of VOCs in the observed effects that are relevant to cosmetic and wound healing aspects.
PB  - MDPI
T2  - Antioxidants
T1  - Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts
VL  - 12
IS  - 11
DO  - 10.3390/antiox12111988
ER  - 

@article{
author = "Smiljanić, Katarina and Prodić, Ivana and Trifunović, Sara and Krstić-Ristivojević, Maja and Aćimović, Milica G. and Stanković Jeremić, Jovana and Lončar, Biljana and Tešević, Vele",
year = "2023",
abstract = "As byproducts of essential oil distillation, hydrolates are used in natural cosmetics/biomedicine due to their beneficial skin effects. However, data on their safety with relevant biological targets, such as human skin cells, are scarce. Therefore, we have tested nine hydrolates from the Lamiaceae family with skin fibroblasts that are responsible for extracellular collagenous matrix builds. Thyme, oregano, and winter savoury hydrolates showed several times higher total phenolics, which correlated strongly with their radical scavenging and antioxidative capacity; there was no correlation between their viability profiles and the reducing sugar levels. No proteins/peptides were detected. All hydrolates appeared safe for prolonged skin exposure except for 10-fold diluted lavender, which showed cytotoxicity (~20%), as well as rosemary and lavandin (~10%) using viability, DNA synthesis, and cell count testing. Clary sage, oregano, lemon balm, and thyme hydrolates (10-fold diluted) increased fibroblast viability and/or proliferation by 10–30% compared with the control, while their viability remained unaffected by Mentha and winter savoury. In line with the STITCH database, increased viability could be attributed to thymol presence in oregano and thyme hydrolates in lemon balm, which is most likely attributable to neral and geranial. The proliferative effect of clary sage could be supported by alpha-terpineol, not linalool. The major volatile organic compounds (VOCs) associated with cytotoxic effects on fibroblasts were borneol, 1,8-cineole, and terpinene-4-ol. Further research with pure compounds is warranted to confirm the roles of VOCs in the observed effects that are relevant to cosmetic and wound healing aspects.",
publisher = "MDPI",
journal = "Antioxidants",
title = "Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts",
volume = "12",
number = "11",
doi = "10.3390/antiox12111988"
}

Smiljanić, K., Prodić, I., Trifunović, S., Krstić-Ristivojević, M., Aćimović, M. G., Stanković Jeremić, J., Lončar, B.,& Tešević, V.. (2023). Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts. in Antioxidants
MDPI., 12(11).
https://doi.org/10.3390/antiox12111988

Smiljanić K, Prodić I, Trifunović S, Krstić-Ristivojević M, Aćimović MG, Stanković Jeremić J, Lončar B, Tešević V. Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts. in Antioxidants. 2023;12(11).
doi:10.3390/antiox12111988 .

Smiljanić, Katarina, Prodić, Ivana, Trifunović, Sara, Krstić-Ristivojević, Maja, Aćimović, Milica G., Stanković Jeremić, Jovana, Lončar, Biljana, Tešević, Vele, "Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts" in Antioxidants, 12, no. 11 (2023),
https://doi.org/10.3390/antiox12111988 . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Stanković-Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Kiprovski, Biljana
AU  - Vidović, Senka
AU  - Vladić, Jelena
AU  - Pezo, Lato
PY  - 2022
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.202100954
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5043
AB  - The most abundant volatile compounds of sweet wormwood (Artemisia annua L.) essential oil were artemisia ketone (25.4 %) and trans-caryophyllene (10.2 %), followed by 1,8-cineole, camphor, germacrene D and β-selinene. The major volatile compounds in the hydrosol were camphor (25.1 %), 1,8-cineole (20.5 %) and artemisia ketone (10.7 %), followed by trans-pinocarveol and yomogi alcohol. Tested essential oil was rich in oxygenated monoterpenes and sesquiterpene hydrocarbons, while the former were identified as the major class of volatile compounds in the hydrosol, due to higher water solubility. Classification of all sweet wormwood chemotypes, according to essential oil composition, in available literature (17 studies and 61 accessions) could be done according to four chemotypes: artemisia ketone+artemisia alcohol (most abundant), artemisia ketone, camphor and nonspecific chemotype. According to this classification, essential oil of sweet wormwood from this study belongs to artemisia ketone (content varied between 22.1 and 55.8 %). Bearing in mind that hydrosols are a by-product of industrial production of essential oils, and the fact that sweet wormwood hydrosol has high contents of camphor, 1,8-cineole and artemisia ketone, there is a great potential for the use of this aromatic plant primary processing waste product as a water replacement in cosmetic industry, beverages flavoring, for food preservation, as well as in post-harvest pre-storage treatments in organic agriculture.
T2  - Chemistry & Biodiversity
T1  - Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia
VL  - 19
IS  - 3
SP  - e202100954
DO  - 10.1002/cbdv.202100954
ER  - 

@article{
author = "Aćimović, Milica G. and Stanković-Jeremić, Jovana and Todosijević, Marina and Kiprovski, Biljana and Vidović, Senka and Vladić, Jelena and Pezo, Lato",
year = "2022",
abstract = "The most abundant volatile compounds of sweet wormwood (Artemisia annua L.) essential oil were artemisia ketone (25.4 %) and trans-caryophyllene (10.2 %), followed by 1,8-cineole, camphor, germacrene D and β-selinene. The major volatile compounds in the hydrosol were camphor (25.1 %), 1,8-cineole (20.5 %) and artemisia ketone (10.7 %), followed by trans-pinocarveol and yomogi alcohol. Tested essential oil was rich in oxygenated monoterpenes and sesquiterpene hydrocarbons, while the former were identified as the major class of volatile compounds in the hydrosol, due to higher water solubility. Classification of all sweet wormwood chemotypes, according to essential oil composition, in available literature (17 studies and 61 accessions) could be done according to four chemotypes: artemisia ketone+artemisia alcohol (most abundant), artemisia ketone, camphor and nonspecific chemotype. According to this classification, essential oil of sweet wormwood from this study belongs to artemisia ketone (content varied between 22.1 and 55.8 %). Bearing in mind that hydrosols are a by-product of industrial production of essential oils, and the fact that sweet wormwood hydrosol has high contents of camphor, 1,8-cineole and artemisia ketone, there is a great potential for the use of this aromatic plant primary processing waste product as a water replacement in cosmetic industry, beverages flavoring, for food preservation, as well as in post-harvest pre-storage treatments in organic agriculture.",
journal = "Chemistry & Biodiversity",
title = "Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia",
volume = "19",
number = "3",
pages = "e202100954",
doi = "10.1002/cbdv.202100954"
}

Aćimović, M. G., Stanković-Jeremić, J., Todosijević, M., Kiprovski, B., Vidović, S., Vladić, J.,& Pezo, L.. (2022). Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia. in Chemistry & Biodiversity, 19(3), e202100954.
https://doi.org/10.1002/cbdv.202100954

Aćimović MG, Stanković-Jeremić J, Todosijević M, Kiprovski B, Vidović S, Vladić J, Pezo L. Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia. in Chemistry & Biodiversity. 2022;19(3):e202100954.
doi:10.1002/cbdv.202100954 .

Aćimović, Milica G., Stanković-Jeremić, Jovana, Todosijević, Marina, Kiprovski, Biljana, Vidović, Senka, Vladić, Jelena, Pezo, Lato, "Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia" in Chemistry & Biodiversity, 19, no. 3 (2022):e202100954,
https://doi.org/10.1002/cbdv.202100954 . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Lončar, Biljana
AU  - Jeremić, Stanković Jovana
AU  - Cvetković, Marijana
AU  - Pezo, Lato
AU  - Pezo, Milada
AU  - Todosijević, Marina
AU  - Tešević, Vele
PY  - 2022
UR  - https://www.mdpi.com/2311-7524/8/4/281
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5115
AB  - Lavandula sp. essential oil and hydrolate are commercially valuable in various industry branches with the potential for wide-ranging applications. This study aimed to evaluate the quality of these products obtained from L. x intermedia cv. ‘Budrovka’ for the first time cultivated on Fruška Gora Mt. (Serbia) during three successive seasons (2019, 2020, and 2021). Essential oil extraction was obtained by steam distillation, and the composition and influence of weather conditions were also assessed, using flowering tops. The obtained essential oils and hydrolates were analysed by gas chromatography with a flame ionization detector (GC-FID) and gas chromatography coupled to mass spectrometry (GC-MS). A linear regression model was developed to predict L. x intermedia cv. ‘Budrovka’ essential oil volatile compound content and hydrolate composition during three years, according to temperature and precipitation data, and the appropriate regression coefficients were calculated, while the correlation analysis was employed to analyse the correlations in hydrolate and essential oil compounds. To completely describe the structure of the research data that would present a better insight into the similarities and differences among the diverse L. x intermedia cv. ‘Budrovka’ samples, the PCA was used. The most dominant in L. intermedia cv. ‘Budrovka’ essential oil and hydrolate were oxygenated monoterpenes: linalool, 1,8-cineole, borneol, linalyl acetate, and terpinene-4-ol. It is established that the temperature was positively correlated with all essential oil and hydrolate compounds. The precipitations were positively correlated with the main compounds (linalool, 1,8-cineole, and borneol), while the other compounds’ content negatively correlated to precipitation. The results indicated that Fruška Gora Mt. has suitable agro-ecological requirements for cultivating Lavandula sp. and providing satisfactory essential oil and hydrolate. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PB  - MDPI
T2  - Horticulturae
T1  - Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality
VL  - 8
IS  - 4
DO  - 10.3390/horticulturae8040281
ER  - 

@article{
author = "Aćimović, Milica G. and Lončar, Biljana and Jeremić, Stanković Jovana and Cvetković, Marijana and Pezo, Lato and Pezo, Milada and Todosijević, Marina and Tešević, Vele",
year = "2022",
abstract = "Lavandula sp. essential oil and hydrolate are commercially valuable in various industry branches with the potential for wide-ranging applications. This study aimed to evaluate the quality of these products obtained from L. x intermedia cv. ‘Budrovka’ for the first time cultivated on Fruška Gora Mt. (Serbia) during three successive seasons (2019, 2020, and 2021). Essential oil extraction was obtained by steam distillation, and the composition and influence of weather conditions were also assessed, using flowering tops. The obtained essential oils and hydrolates were analysed by gas chromatography with a flame ionization detector (GC-FID) and gas chromatography coupled to mass spectrometry (GC-MS). A linear regression model was developed to predict L. x intermedia cv. ‘Budrovka’ essential oil volatile compound content and hydrolate composition during three years, according to temperature and precipitation data, and the appropriate regression coefficients were calculated, while the correlation analysis was employed to analyse the correlations in hydrolate and essential oil compounds. To completely describe the structure of the research data that would present a better insight into the similarities and differences among the diverse L. x intermedia cv. ‘Budrovka’ samples, the PCA was used. The most dominant in L. intermedia cv. ‘Budrovka’ essential oil and hydrolate were oxygenated monoterpenes: linalool, 1,8-cineole, borneol, linalyl acetate, and terpinene-4-ol. It is established that the temperature was positively correlated with all essential oil and hydrolate compounds. The precipitations were positively correlated with the main compounds (linalool, 1,8-cineole, and borneol), while the other compounds’ content negatively correlated to precipitation. The results indicated that Fruška Gora Mt. has suitable agro-ecological requirements for cultivating Lavandula sp. and providing satisfactory essential oil and hydrolate. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
publisher = "MDPI",
journal = "Horticulturae",
title = "Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality",
volume = "8",
number = "4",
doi = "10.3390/horticulturae8040281"
}

Aćimović, M. G., Lončar, B., Jeremić, S. J., Cvetković, M., Pezo, L., Pezo, M., Todosijević, M.,& Tešević, V.. (2022). Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality. in Horticulturae
MDPI., 8(4).
https://doi.org/10.3390/horticulturae8040281

Aćimović MG, Lončar B, Jeremić SJ, Cvetković M, Pezo L, Pezo M, Todosijević M, Tešević V. Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality. in Horticulturae. 2022;8(4).
doi:10.3390/horticulturae8040281 .

Aćimović, Milica G., Lončar, Biljana, Jeremić, Stanković Jovana, Cvetković, Marijana, Pezo, Lato, Pezo, Milada, Todosijević, Marina, Tešević, Vele, "Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality" in Horticulturae, 8, no. 4 (2022),
https://doi.org/10.3390/horticulturae8040281 . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković-Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5614
AB  - This study aimed to investigate the chemical composition of steam distillate essential oil
and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence
of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,
their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different
from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among
the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the
tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration
(MBC/MFC) were 14.20 and 28.4 µL mL−1
, respectively). MIC and MBC values of other tested
bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged
from 28.40/56.81 to 56.81–113.63 µL mL−1
. Antibiotic susceptibility patterns for the analyzed eight
respiratory-associated microorganisms showed an intermediate level of resistance to commonly used
antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the
antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess
remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an
alternative to conventional antibiotic therapy
PB  - MDPI
T2  - Processes
T1  - Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity
VL  - 10
IS  - 8
SP  - 1608
DO  - 10.3390/pr10081608
ER  - 

@article{
author = "Aćimović, Milica G. and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković-Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oil
and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence
of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,
their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different
from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among
the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the
tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration
(MBC/MFC) were 14.20 and 28.4 µL mL−1
, respectively). MIC and MBC values of other tested
bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged
from 28.40/56.81 to 56.81–113.63 µL mL−1
. Antibiotic susceptibility patterns for the analyzed eight
respiratory-associated microorganisms showed an intermediate level of resistance to commonly used
antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the
antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess
remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an
alternative to conventional antibiotic therapy",
publisher = "MDPI",
journal = "Processes",
title = "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity",
volume = "10",
number = "8",
pages = "1608",
doi = "10.3390/pr10081608"
}

Aćimović, M. G., Pezo, L., Čabarkapa, I., Trudić, A., Stanković-Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes
MDPI., 10(8), 1608.
https://doi.org/10.3390/pr10081608

Aćimović MG, Pezo L, Čabarkapa I, Trudić A, Stanković-Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes. 2022;10(8):1608.
doi:10.3390/pr10081608 .

Aćimović, Milica G., Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković-Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity" in Processes, 10, no. 8 (2022):1608,
https://doi.org/10.3390/pr10081608 . .

TY  - DATA
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković-Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5618
AB  - This study aimed to investigate the chemical composition of steam distillate essential oiland corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influenceof weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly differentfrom the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Amongthe eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to thetested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration(MBC/MFC) were 14.20 and 28.4 µL mL−1, respectively). MIC and MBC values of other testedbacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC rangedfrom 28.40/56.81 to 56.81–113.63 µL mL−1. Antibiotic susceptibility patterns for the analyzed eightrespiratory-associated microorganisms showed an intermediate level of resistance to commonly usedantibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to theantimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possessremarkable antibacterial activities and could be used to develop pharmaceutical formulations as analternative to conventional antibiotic therapy
PB  - MDPI
T2  - Processes
T1  - Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.
VL  - 10
IS  - 8
SP  - 1608
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5618
ER  - 

@misc{
author = "Aćimović, Milica G. and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković-Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oiland corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influenceof weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly differentfrom the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Amongthe eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to thetested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration(MBC/MFC) were 14.20 and 28.4 µL mL−1, respectively). MIC and MBC values of other testedbacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC rangedfrom 28.40/56.81 to 56.81–113.63 µL mL−1. Antibiotic susceptibility patterns for the analyzed eightrespiratory-associated microorganisms showed an intermediate level of resistance to commonly usedantibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to theantimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possessremarkable antibacterial activities and could be used to develop pharmaceutical formulations as analternative to conventional antibiotic therapy",
publisher = "MDPI",
journal = "Processes",
title = "Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.",
volume = "10",
number = "8",
pages = "1608",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5618"
}

Aćimović, M. G., Pezo, L., Čabarkapa, I., Trudić, A., Stanković-Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.. in Processes
MDPI., 10(8), 1608.
https://hdl.handle.net/21.15107/rcub_cherry_5618

Aćimović MG, Pezo L, Čabarkapa I, Trudić A, Stanković-Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.. in Processes. 2022;10(8):1608.
https://hdl.handle.net/21.15107/rcub_cherry_5618 .

Aćimović, Milica G., Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković-Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608." in Processes, 10, no. 8 (2022):1608,
https://hdl.handle.net/21.15107/rcub_cherry_5618 .

TY  - JOUR
AU  - Šovljanski, Olja
AU  - Saveljić, Anja
AU  - Aćimović, Milica G.
AU  - Šeregelj, Vanja
AU  - Pezo, Lato
AU  - Tomić, Ana
AU  - Ćetković, Gordana
AU  - Tešević, Vele
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5645
AB  - e genus Ocimum has many species that are used to treat diverse kinds of illnesses and sicknesses from ancient times. One of them, Ocimum basilicum L., commonly known as basil, has a vital role due to its various medicinal goods. It is best known as a plant with pharmacological activities, but also as an antioxidant, antimicrobial, and larvicidal agent. Although it has been traditionally used in Serbia in traditional medicine for centuries as an insecticidal, antibacterial, and antifungal plant as well as a traditional culinary plant, none of the O. basilicum varieties have been commercialised until today. There are significant numbers of information across the world that oils and by-products are part of the global market, but no references to the essential oil composition of Serbian plants were found. Therefore, the objective of this work was to evaluate the antioxidant and antimicrobial potentials of essential oil and hydrolate of two different varieties: O. basilicum var. genovese and Ocimum. basilicum var. minimum originating from Serbia for further industrial production of antimicrobial- and/or antioxidant-valued products. The results of this study confirm that essential oils of O. basilicum var. genovese and var. minimum represent a significant source of bioactive compounds, especially linalool, with a high rate of biological activities. Similar behaviour is observed for hydrolates, which are the by-product of the essential oil distillation process and can be utilised as bioactive-rich waste in further investigation.
PB  - MDPI
T2  - Processes
T1  - Biological Profiling of Essential Oils and Hydrolates of Ocimum basilicum var. Genovese and var. Minimum Originated from Serbia
VL  - 10
SP  - 1893
DO  - 10.3390/pr10091893
ER  - 

@article{
author = "Šovljanski, Olja and Saveljić, Anja and Aćimović, Milica G. and Šeregelj, Vanja and Pezo, Lato and Tomić, Ana and Ćetković, Gordana and Tešević, Vele",
year = "2022",
abstract = "e genus Ocimum has many species that are used to treat diverse kinds of illnesses and sicknesses from ancient times. One of them, Ocimum basilicum L., commonly known as basil, has a vital role due to its various medicinal goods. It is best known as a plant with pharmacological activities, but also as an antioxidant, antimicrobial, and larvicidal agent. Although it has been traditionally used in Serbia in traditional medicine for centuries as an insecticidal, antibacterial, and antifungal plant as well as a traditional culinary plant, none of the O. basilicum varieties have been commercialised until today. There are significant numbers of information across the world that oils and by-products are part of the global market, but no references to the essential oil composition of Serbian plants were found. Therefore, the objective of this work was to evaluate the antioxidant and antimicrobial potentials of essential oil and hydrolate of two different varieties: O. basilicum var. genovese and Ocimum. basilicum var. minimum originating from Serbia for further industrial production of antimicrobial- and/or antioxidant-valued products. The results of this study confirm that essential oils of O. basilicum var. genovese and var. minimum represent a significant source of bioactive compounds, especially linalool, with a high rate of biological activities. Similar behaviour is observed for hydrolates, which are the by-product of the essential oil distillation process and can be utilised as bioactive-rich waste in further investigation.",
publisher = "MDPI",
journal = "Processes",
title = "Biological Profiling of Essential Oils and Hydrolates of Ocimum basilicum var. Genovese and var. Minimum Originated from Serbia",
volume = "10",
pages = "1893",
doi = "10.3390/pr10091893"
}

Šovljanski, O., Saveljić, A., Aćimović, M. G., Šeregelj, V., Pezo, L., Tomić, A., Ćetković, G.,& Tešević, V.. (2022). Biological Profiling of Essential Oils and Hydrolates of Ocimum basilicum var. Genovese and var. Minimum Originated from Serbia. in Processes
MDPI., 10, 1893.
https://doi.org/10.3390/pr10091893

Šovljanski O, Saveljić A, Aćimović MG, Šeregelj V, Pezo L, Tomić A, Ćetković G, Tešević V. Biological Profiling of Essential Oils and Hydrolates of Ocimum basilicum var. Genovese and var. Minimum Originated from Serbia. in Processes. 2022;10:1893.
doi:10.3390/pr10091893 .

Šovljanski, Olja, Saveljić, Anja, Aćimović, Milica G., Šeregelj, Vanja, Pezo, Lato, Tomić, Ana, Ćetković, Gordana, Tešević, Vele, "Biological Profiling of Essential Oils and Hydrolates of Ocimum basilicum var. Genovese and var. Minimum Originated from Serbia" in Processes, 10 (2022):1893,
https://doi.org/10.3390/pr10091893 . .

TY  - DATA
AU  - Šovljanski, Olja
AU  - Saveljić, Anja
AU  - Aćimović, Milica G.
AU  - Šeregelj, Vanja
AU  - Pezo, Lato
AU  - Tomić, Ana
AU  - Ćetković, Gordana
AU  - Tešević, Vele
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5647
AB  - The genus Ocimum has many species that are used to treat diverse kinds of illnesses and sicknesses from ancient times. One of them, Ocimum basilicum L., commonly known as basil, has a vital role due to its various medicinal goods. It is best known as a plant with pharmacological activities, but also as an antioxidant, antimicrobial, and larvicidal agent. Although it has been traditionally used in Serbia in traditional medicine for centuries as an insecticidal, antibacterial, and antifungal plant as well as a traditional culinary plant, none of the O. basilicum varieties have been commercialised until today. There are significant numbers of information across the world that oils and by-products are part of the global market, but no references to the essential oil composition of Serbian plants were found. Therefore, the objective of this work was to evaluate the antioxidant and antimicrobial potentials of essential oil and hydrolate of two different varieties: O. basilicum var. genovese and Ocimum. basilicum var. minimum originating from Serbia for further industrial production of antimicrobial- and/or antioxidant-valued products. The results of this study confirm that essential oils of O. basilicum var. genovese and var. minimum represent a significant source of bioactive compounds, especially linalool, with a high rate of biological activities. Similar behaviour is observed for hydrolates, which are the by-product of the essential oil distillation process and can be utilised as bioactive-rich waste in further investigation.
PB  - MDPI
T2  - Processes
T1  - Supplementary material for: Šovljanski, O.; Saveljić, A.; Aćimović, M.; Šeregelj, V.; Pezo, L.; Tomić, A.; Ćetković, G.; Tešević, V. Biological Profiling of Essential Oils and Hydrolates of Ocimum Basilicum Var. Genovese and Var. Minimum Originated from Serbia. Processes 2022, 10 (9), 1893. https://doi.org/10.3390/pr10091893
VL  - 10
SP  - 1893
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5647
ER  - 

@misc{
author = "Šovljanski, Olja and Saveljić, Anja and Aćimović, Milica G. and Šeregelj, Vanja and Pezo, Lato and Tomić, Ana and Ćetković, Gordana and Tešević, Vele",
year = "2022",
abstract = "The genus Ocimum has many species that are used to treat diverse kinds of illnesses and sicknesses from ancient times. One of them, Ocimum basilicum L., commonly known as basil, has a vital role due to its various medicinal goods. It is best known as a plant with pharmacological activities, but also as an antioxidant, antimicrobial, and larvicidal agent. Although it has been traditionally used in Serbia in traditional medicine for centuries as an insecticidal, antibacterial, and antifungal plant as well as a traditional culinary plant, none of the O. basilicum varieties have been commercialised until today. There are significant numbers of information across the world that oils and by-products are part of the global market, but no references to the essential oil composition of Serbian plants were found. Therefore, the objective of this work was to evaluate the antioxidant and antimicrobial potentials of essential oil and hydrolate of two different varieties: O. basilicum var. genovese and Ocimum. basilicum var. minimum originating from Serbia for further industrial production of antimicrobial- and/or antioxidant-valued products. The results of this study confirm that essential oils of O. basilicum var. genovese and var. minimum represent a significant source of bioactive compounds, especially linalool, with a high rate of biological activities. Similar behaviour is observed for hydrolates, which are the by-product of the essential oil distillation process and can be utilised as bioactive-rich waste in further investigation.",
publisher = "MDPI",
journal = "Processes",
title = "Supplementary material for: Šovljanski, O.; Saveljić, A.; Aćimović, M.; Šeregelj, V.; Pezo, L.; Tomić, A.; Ćetković, G.; Tešević, V. Biological Profiling of Essential Oils and Hydrolates of Ocimum Basilicum Var. Genovese and Var. Minimum Originated from Serbia. Processes 2022, 10 (9), 1893. https://doi.org/10.3390/pr10091893",
volume = "10",
pages = "1893",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5647"
}

Šovljanski, O., Saveljić, A., Aćimović, M. G., Šeregelj, V., Pezo, L., Tomić, A., Ćetković, G.,& Tešević, V.. (2022). Supplementary material for: Šovljanski, O.; Saveljić, A.; Aćimović, M.; Šeregelj, V.; Pezo, L.; Tomić, A.; Ćetković, G.; Tešević, V. Biological Profiling of Essential Oils and Hydrolates of Ocimum Basilicum Var. Genovese and Var. Minimum Originated from Serbia. Processes 2022, 10 (9), 1893. https://doi.org/10.3390/pr10091893. in Processes
MDPI., 10, 1893.
https://hdl.handle.net/21.15107/rcub_cherry_5647

Šovljanski O, Saveljić A, Aćimović MG, Šeregelj V, Pezo L, Tomić A, Ćetković G, Tešević V. Supplementary material for: Šovljanski, O.; Saveljić, A.; Aćimović, M.; Šeregelj, V.; Pezo, L.; Tomić, A.; Ćetković, G.; Tešević, V. Biological Profiling of Essential Oils and Hydrolates of Ocimum Basilicum Var. Genovese and Var. Minimum Originated from Serbia. Processes 2022, 10 (9), 1893. https://doi.org/10.3390/pr10091893. in Processes. 2022;10:1893.
https://hdl.handle.net/21.15107/rcub_cherry_5647 .

Šovljanski, Olja, Saveljić, Anja, Aćimović, Milica G., Šeregelj, Vanja, Pezo, Lato, Tomić, Ana, Ćetković, Gordana, Tešević, Vele, "Supplementary material for: Šovljanski, O.; Saveljić, A.; Aćimović, M.; Šeregelj, V.; Pezo, L.; Tomić, A.; Ćetković, G.; Tešević, V. Biological Profiling of Essential Oils and Hydrolates of Ocimum Basilicum Var. Genovese and Var. Minimum Originated from Serbia. Processes 2022, 10 (9), 1893. https://doi.org/10.3390/pr10091893" in Processes, 10 (2022):1893,
https://hdl.handle.net/21.15107/rcub_cherry_5647 .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Lončar, Biljana
AU  - Jeliazkov, Valtcho
AU  - Pezo, Lato
AU  - Ljujić, Jovana
AU  - Miljković, Ana
AU  - Vujisić, Ljubodrag V.
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5983
AB  - The volatile compounds of essential oil (EO) and corresponding hydrolate (HY) extracted by steam distillation from clary sage (Salvia sclarea L.) cv “Domaća mirisna” grown in Serbia were identified using gas hromatography/mass spectrometry (GC/MS). The most abundant compounds of EO were linalyl acetate (43.5%) and linalool (25.9%), followed by α-terpineol, germacrene D, and geranyl acetate. In the corresponding HY (recovered water-soluble fraction of EO) the dominant were linalool (63.3%) and α-terpineol (26.8%), followed by geraniol. These differences in composition between clary sage EO and HY could be explained by linalyl acetate's low water solubility. Clustering of 55 clary sage EO accessions (from literature) shows the presence of several chemotypes: linalyl acetate+linalool, linalyl acetate+sclareol, linalool+geranyl acetate, germacrene D+β-caryophyllene, caryophyllene oxide, and three unspecified chemotypes (geranyl acetate, methyl chavicol, and α-terpineol). According to this classification, clary sage cv “Domaća mirisna” belongs to a moderate linalyl acetate chemotype (between 19.8 and 45.7%). Further investigations need to focus on clary sage HY and their potential applications because HYs could increase economic gain as a by-product. However, their utilization for other purposes (cosmetic, postharvest fruit processing, organic agriculture, etc.) could be a safe solution for wastewater produced during EO distillation.
PB  - Taylor & Francis
T2  - Journal of Essential Oil Bearing Plants
T1  - Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate
VL  - 25
IS  - 3
SP  - 555
EP  - 570
DO  - 10.1080/0972060X.2022.2105662
ER  - 

@article{
author = "Aćimović, Milica G. and Lončar, Biljana and Jeliazkov, Valtcho and Pezo, Lato and Ljujić, Jovana and Miljković, Ana and Vujisić, Ljubodrag V.",
year = "2022",
abstract = "The volatile compounds of essential oil (EO) and corresponding hydrolate (HY) extracted by steam distillation from clary sage (Salvia sclarea L.) cv “Domaća mirisna” grown in Serbia were identified using gas hromatography/mass spectrometry (GC/MS). The most abundant compounds of EO were linalyl acetate (43.5%) and linalool (25.9%), followed by α-terpineol, germacrene D, and geranyl acetate. In the corresponding HY (recovered water-soluble fraction of EO) the dominant were linalool (63.3%) and α-terpineol (26.8%), followed by geraniol. These differences in composition between clary sage EO and HY could be explained by linalyl acetate's low water solubility. Clustering of 55 clary sage EO accessions (from literature) shows the presence of several chemotypes: linalyl acetate+linalool, linalyl acetate+sclareol, linalool+geranyl acetate, germacrene D+β-caryophyllene, caryophyllene oxide, and three unspecified chemotypes (geranyl acetate, methyl chavicol, and α-terpineol). According to this classification, clary sage cv “Domaća mirisna” belongs to a moderate linalyl acetate chemotype (between 19.8 and 45.7%). Further investigations need to focus on clary sage HY and their potential applications because HYs could increase economic gain as a by-product. However, their utilization for other purposes (cosmetic, postharvest fruit processing, organic agriculture, etc.) could be a safe solution for wastewater produced during EO distillation.",
publisher = "Taylor & Francis",
journal = "Journal of Essential Oil Bearing Plants",
title = "Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate",
volume = "25",
number = "3",
pages = "555-570",
doi = "10.1080/0972060X.2022.2105662"
}

Aćimović, M. G., Lončar, B., Jeliazkov, V., Pezo, L., Ljujić, J., Miljković, A.,& Vujisić, L. V.. (2022). Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate. in Journal of Essential Oil Bearing Plants
Taylor & Francis., 25(3), 555-570.
https://doi.org/10.1080/0972060X.2022.2105662

Aćimović MG, Lončar B, Jeliazkov V, Pezo L, Ljujić J, Miljković A, Vujisić LV. Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate. in Journal of Essential Oil Bearing Plants. 2022;25(3):555-570.
doi:10.1080/0972060X.2022.2105662 .

Aćimović, Milica G., Lončar, Biljana, Jeliazkov, Valtcho, Pezo, Lato, Ljujić, Jovana, Miljković, Ana, Vujisić, Ljubodrag V., "Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate" in Journal of Essential Oil Bearing Plants, 25, no. 3 (2022):555-570,
https://doi.org/10.1080/0972060X.2022.2105662 . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Lončar, Biljana
AU  - Jeliazkov, Valtcho
AU  - Pezo, Lato
AU  - Ljujić, Jovana
AU  - Miljković, Ana
AU  - Vujisić, Ljubodrag V.
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5984
AB  - The volatile compounds of essential oil (EO) and corresponding hydrolate (HY) extracted by steam distillation from clary sage (Salvia sclarea L.) cv “Domaća mirisna” grown in Serbia were identified using gas hromatography/mass spectrometry (GC/MS). The most abundant compounds of EO were linalyl acetate (43.5%) and linalool (25.9%), followed by α-terpineol, germacrene D, and geranyl acetate. In the corresponding HY (recovered water-soluble fraction of EO) the dominant were linalool (63.3%) and α-terpineol (26.8%), followed by geraniol. These differences in composition between clary sage EO and HY could be explained by linalyl acetate's low water solubility. Clustering of 55 clary sage EO accessions (from literature) shows the presence of several chemotypes: linalyl acetate+linalool, linalyl acetate+sclareol, linalool+geranyl acetate, germacrene D+β-caryophyllene, caryophyllene oxide, and three unspecified chemotypes (geranyl acetate, methyl chavicol, and α-terpineol). According to this classification, clary sage cv “Domaća mirisna” belongs to a moderate linalyl acetate chemotype (between 19.8 and 45.7%). Further investigations need to focus on clary sage HY and their potential applications because HYs could increase economic gain as a by-product. However, their utilization for other purposes (cosmetic, postharvest fruit processing, organic agriculture, etc.) could be a safe solution for wastewater produced during EO distillation.
PB  - Taylor & Francis
T2  - Journal of Essential Oil Bearing Plants
T1  - Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate
VL  - 25
IS  - 3
SP  - 555
EP  - 570
DO  - 10.1080/0972060X.2022.2105662
ER  - 

@article{
author = "Aćimović, Milica G. and Lončar, Biljana and Jeliazkov, Valtcho and Pezo, Lato and Ljujić, Jovana and Miljković, Ana and Vujisić, Ljubodrag V.",
year = "2022",
abstract = "The volatile compounds of essential oil (EO) and corresponding hydrolate (HY) extracted by steam distillation from clary sage (Salvia sclarea L.) cv “Domaća mirisna” grown in Serbia were identified using gas hromatography/mass spectrometry (GC/MS). The most abundant compounds of EO were linalyl acetate (43.5%) and linalool (25.9%), followed by α-terpineol, germacrene D, and geranyl acetate. In the corresponding HY (recovered water-soluble fraction of EO) the dominant were linalool (63.3%) and α-terpineol (26.8%), followed by geraniol. These differences in composition between clary sage EO and HY could be explained by linalyl acetate's low water solubility. Clustering of 55 clary sage EO accessions (from literature) shows the presence of several chemotypes: linalyl acetate+linalool, linalyl acetate+sclareol, linalool+geranyl acetate, germacrene D+β-caryophyllene, caryophyllene oxide, and three unspecified chemotypes (geranyl acetate, methyl chavicol, and α-terpineol). According to this classification, clary sage cv “Domaća mirisna” belongs to a moderate linalyl acetate chemotype (between 19.8 and 45.7%). Further investigations need to focus on clary sage HY and their potential applications because HYs could increase economic gain as a by-product. However, their utilization for other purposes (cosmetic, postharvest fruit processing, organic agriculture, etc.) could be a safe solution for wastewater produced during EO distillation.",
publisher = "Taylor & Francis",
journal = "Journal of Essential Oil Bearing Plants",
title = "Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate",
volume = "25",
number = "3",
pages = "555-570",
doi = "10.1080/0972060X.2022.2105662"
}

Aćimović, M. G., Lončar, B., Jeliazkov, V., Pezo, L., Ljujić, J., Miljković, A.,& Vujisić, L. V.. (2022). Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate. in Journal of Essential Oil Bearing Plants
Taylor & Francis., 25(3), 555-570.
https://doi.org/10.1080/0972060X.2022.2105662

Aćimović MG, Lončar B, Jeliazkov V, Pezo L, Ljujić J, Miljković A, Vujisić LV. Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate. in Journal of Essential Oil Bearing Plants. 2022;25(3):555-570.
doi:10.1080/0972060X.2022.2105662 .

Aćimović, Milica G., Lončar, Biljana, Jeliazkov, Valtcho, Pezo, Lato, Ljujić, Jovana, Miljković, Ana, Vujisić, Ljubodrag V., "Comparison of volatile compounds from clary sage (Salvia sclarea L.) verticillasters essential oil and hydrolate" in Journal of Essential Oil Bearing Plants, 25, no. 3 (2022):555-570,
https://doi.org/10.1080/0972060X.2022.2105662 . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Šovljanski, Olja
AU  - Pezo, Lato
AU  - Travičić, Vanja
AU  - Tomić, Ana
AU  - Zheljazkov, Valtcho D.
AU  - Ćetković, Gordana
AU  - Švarc-Gajić, Jaroslava
AU  - Brezo-Borjan, Tanja
AU  - Sofrenić, Ivana
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5656
AB  - Winter savory (Satureja montana L.) is a well-known spice and medicinal plant with a wide range of activities and applications. Two subspecies of S. montana, subsp. montana and subsp. variegata, were used for the preparation of seven different extracts: steam distillation (essential oil (EO) and hydrolate (HY)), subcritical water (SWE), ultrasound-assisted (UAE-MeOH and UAE-H2O), and microwave-assisted (MAE-MeOH and MAE-H2O) extraction. The obtained EOs, HYs, and extracts were used for an in vitro evaluation of the antioxidant activity (DPPH, ABTS, reducing power, and superoxide anion methods) and in vitro antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Salmonella Typhimurium, Saccharomyces cerevisiae, and Candida albicans. The antimicrobial screening was conducted using disk-diffusion assessment, minimal inhibitory concentration, time–kill kinetics modeling, and pharmacodynamic study of the biocide effect. The total phenolic content (TPC) was highest in EO, followed by SWE, MAE, and UAE, and the lowest was in HY. The highest antimicrobial activity shows EO and SWE for both varieties, while different UAE and MAE extracts have not exhibited antimicrobial activity. The natural antimicrobials in the S. montana extract samples obtained by green extraction methods, indicated the possibility of ecologically and economically better solutions for future in vivo application of the selected plant subspecies.
PB  - MDPI
T2  - Antibiotics
T1  - Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods
VL  - 11
SP  - 1235
DO  - 10.3390/antibiotics11091235
ER  - 

@article{
author = "Aćimović, Milica G. and Šovljanski, Olja and Pezo, Lato and Travičić, Vanja and Tomić, Ana and Zheljazkov, Valtcho D. and Ćetković, Gordana and Švarc-Gajić, Jaroslava and Brezo-Borjan, Tanja and Sofrenić, Ivana",
year = "2022",
abstract = "Winter savory (Satureja montana L.) is a well-known spice and medicinal plant with a wide range of activities and applications. Two subspecies of S. montana, subsp. montana and subsp. variegata, were used for the preparation of seven different extracts: steam distillation (essential oil (EO) and hydrolate (HY)), subcritical water (SWE), ultrasound-assisted (UAE-MeOH and UAE-H2O), and microwave-assisted (MAE-MeOH and MAE-H2O) extraction. The obtained EOs, HYs, and extracts were used for an in vitro evaluation of the antioxidant activity (DPPH, ABTS, reducing power, and superoxide anion methods) and in vitro antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Salmonella Typhimurium, Saccharomyces cerevisiae, and Candida albicans. The antimicrobial screening was conducted using disk-diffusion assessment, minimal inhibitory concentration, time–kill kinetics modeling, and pharmacodynamic study of the biocide effect. The total phenolic content (TPC) was highest in EO, followed by SWE, MAE, and UAE, and the lowest was in HY. The highest antimicrobial activity shows EO and SWE for both varieties, while different UAE and MAE extracts have not exhibited antimicrobial activity. The natural antimicrobials in the S. montana extract samples obtained by green extraction methods, indicated the possibility of ecologically and economically better solutions for future in vivo application of the selected plant subspecies.",
publisher = "MDPI",
journal = "Antibiotics",
title = "Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods",
volume = "11",
pages = "1235",
doi = "10.3390/antibiotics11091235"
}

Aćimović, M. G., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics
MDPI., 11, 1235.
https://doi.org/10.3390/antibiotics11091235

Aćimović MG, Šovljanski O, Pezo L, Travičić V, Tomić A, Zheljazkov VD, Ćetković G, Švarc-Gajić J, Brezo-Borjan T, Sofrenić I. Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics. 2022;11:1235.
doi:10.3390/antibiotics11091235 .

Aćimović, Milica G., Šovljanski, Olja, Pezo, Lato, Travičić, Vanja, Tomić, Ana, Zheljazkov, Valtcho D., Ćetković, Gordana, Švarc-Gajić, Jaroslava, Brezo-Borjan, Tanja, Sofrenić, Ivana, "Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods" in Antibiotics, 11 (2022):1235,
https://doi.org/10.3390/antibiotics11091235 . .

TY  - DATA
AU  - Aćimović, Milica G.
AU  - Šovljanski, Olja
AU  - Pezo, Lato
AU  - Travičić, Vanja
AU  - Tomić, Ana
AU  - Zheljazkov, Valtcho D.
AU  - Ćetković, Gordana
AU  - Švarc-Gajić, Jaroslava
AU  - Brezo-Borjan, Tanja
AU  - Sofrenić, Ivana
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5661
AB  - Winter savory (Satureja montana L.) is a well-known spice and medicinal plant with a wide range of activities and applications. Two subspecies of S. montana, subsp. montana and subsp. variegata, were used for the preparation of seven different extracts: steam distillation (essential oil (EO) and hydrolate (HY)), subcritical water (SWE), ultrasound-assisted (UAE-MeOH and UAE-H2O), and microwave-assisted (MAE-MeOH and MAE-H2O) extraction. The obtained EOs, HYs, and extracts were used for an in vitro evaluation of the antioxidant activity (DPPH, ABTS, reducing power, and superoxide anion methods) and in vitro antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Salmonella Typhimurium, Saccharomyces cerevisiae, and Candida albicans. The antimicrobial screening was conducted using disk-diffusion assessment, minimal inhibitory concentration, time–kill kinetics modeling, and pharmacodynamic study of the biocide effect. The total phenolic content (TPC) was highest in EO, followed by SWE, MAE, and UAE, and the lowest was in HY. The highest antimicrobial activity shows EO and SWE for both varieties, while different UAE and MAE extracts have not exhibited antimicrobial activity. The natural antimicrobials in the S. montana extract samples obtained by green extraction methods, indicated the possibility of ecologically and economically better solutions for future in vivo application of the selected plant subspecies.
PB  - MDPI
T2  - Antibiotics
T1  - Supplementary material for: Aćimović, M., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics MDPI., 11, 1235. https://doi.org/10.3390/antibiotics11091235
VL  - 11
SP  - 1235
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5661
ER  - 

@misc{
author = "Aćimović, Milica G. and Šovljanski, Olja and Pezo, Lato and Travičić, Vanja and Tomić, Ana and Zheljazkov, Valtcho D. and Ćetković, Gordana and Švarc-Gajić, Jaroslava and Brezo-Borjan, Tanja and Sofrenić, Ivana",
year = "2022",
abstract = "Winter savory (Satureja montana L.) is a well-known spice and medicinal plant with a wide range of activities and applications. Two subspecies of S. montana, subsp. montana and subsp. variegata, were used for the preparation of seven different extracts: steam distillation (essential oil (EO) and hydrolate (HY)), subcritical water (SWE), ultrasound-assisted (UAE-MeOH and UAE-H2O), and microwave-assisted (MAE-MeOH and MAE-H2O) extraction. The obtained EOs, HYs, and extracts were used for an in vitro evaluation of the antioxidant activity (DPPH, ABTS, reducing power, and superoxide anion methods) and in vitro antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Salmonella Typhimurium, Saccharomyces cerevisiae, and Candida albicans. The antimicrobial screening was conducted using disk-diffusion assessment, minimal inhibitory concentration, time–kill kinetics modeling, and pharmacodynamic study of the biocide effect. The total phenolic content (TPC) was highest in EO, followed by SWE, MAE, and UAE, and the lowest was in HY. The highest antimicrobial activity shows EO and SWE for both varieties, while different UAE and MAE extracts have not exhibited antimicrobial activity. The natural antimicrobials in the S. montana extract samples obtained by green extraction methods, indicated the possibility of ecologically and economically better solutions for future in vivo application of the selected plant subspecies.",
publisher = "MDPI",
journal = "Antibiotics",
title = "Supplementary material for: Aćimović, M., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics MDPI., 11, 1235. https://doi.org/10.3390/antibiotics11091235",
volume = "11",
pages = "1235",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5661"
}

Aćimović, M. G., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Supplementary material for: Aćimović, M., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics MDPI., 11, 1235. https://doi.org/10.3390/antibiotics11091235. in Antibiotics
MDPI., 11, 1235.
https://hdl.handle.net/21.15107/rcub_cherry_5661

Aćimović MG, Šovljanski O, Pezo L, Travičić V, Tomić A, Zheljazkov VD, Ćetković G, Švarc-Gajić J, Brezo-Borjan T, Sofrenić I. Supplementary material for: Aćimović, M., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics MDPI., 11, 1235. https://doi.org/10.3390/antibiotics11091235. in Antibiotics. 2022;11:1235.
https://hdl.handle.net/21.15107/rcub_cherry_5661 .

Aćimović, Milica G., Šovljanski, Olja, Pezo, Lato, Travičić, Vanja, Tomić, Ana, Zheljazkov, Valtcho D., Ćetković, Gordana, Švarc-Gajić, Jaroslava, Brezo-Borjan, Tanja, Sofrenić, Ivana, "Supplementary material for: Aćimović, M., Šovljanski, O., Pezo, L., Travičić, V., Tomić, A., Zheljazkov, V. D., Ćetković, G., Švarc-Gajić, J., Brezo-Borjan, T.,& Sofrenić, I.. (2022). Variability in Biological Activities of Satureja montana Subsp. montana and Subsp. variegata Based on Different Extraction Methods. in Antibiotics MDPI., 11, 1235. https://doi.org/10.3390/antibiotics11091235" in Antibiotics, 11 (2022):1235,
https://hdl.handle.net/21.15107/rcub_cherry_5661 .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Stanković-Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Rat, Milica
AU  - Tešević, Vele
AU  - Cvetković, Mirjana
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5016
AB  - In the essential oil of yarrow (Achillea millefolium L. sensu lato) collected from natural population on Mt. Rtanj (Serbia) and distilled by Clevenger apparatus 104 compounds were detected, and
the most abundant were camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-
cineole (5.6%). The quantitative structure-retention relationship (QSRR) model was employed to predict the retention indices, using four molecular descriptors selected by factor analysis and a genetic
algorithm. The coefficients of determination reached the value of 0.862, demonstrating that this model could be used for prediction purposes.
PB  - University of Novi Sad, Faculty of Technology
T2  - Acta periodica technologica
T1  - The quantitative structure-retention relationship of the gc-ms profile of yarrow essential oil
IS  - 52
SP  - 123
EP  - 132
DO  - 10.2298/APT2152123A
ER  - 

@article{
author = "Aćimović, Milica G. and Pezo, Lato and Stanković-Jeremić, Jovana and Todosijević, Marina and Rat, Milica and Tešević, Vele and Cvetković, Mirjana",
year = "2021",
abstract = "In the essential oil of yarrow (Achillea millefolium L. sensu lato) collected from natural population on Mt. Rtanj (Serbia) and distilled by Clevenger apparatus 104 compounds were detected, and
the most abundant were camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-
cineole (5.6%). The quantitative structure-retention relationship (QSRR) model was employed to predict the retention indices, using four molecular descriptors selected by factor analysis and a genetic
algorithm. The coefficients of determination reached the value of 0.862, demonstrating that this model could be used for prediction purposes.",
publisher = "University of Novi Sad, Faculty of Technology",
journal = "Acta periodica technologica",
title = "The quantitative structure-retention relationship of the gc-ms profile of yarrow essential oil",
number = "52",
pages = "123-132",
doi = "10.2298/APT2152123A"
}

Aćimović, M. G., Pezo, L., Stanković-Jeremić, J., Todosijević, M., Rat, M., Tešević, V.,& Cvetković, M.. (2021). The quantitative structure-retention relationship of the gc-ms profile of yarrow essential oil. in Acta periodica technologica
University of Novi Sad, Faculty of Technology.(52), 123-132.
https://doi.org/10.2298/APT2152123A

Aćimović MG, Pezo L, Stanković-Jeremić J, Todosijević M, Rat M, Tešević V, Cvetković M. The quantitative structure-retention relationship of the gc-ms profile of yarrow essential oil. in Acta periodica technologica. 2021;(52):123-132.
doi:10.2298/APT2152123A .

Aćimović, Milica G., Pezo, Lato, Stanković-Jeremić, Jovana, Todosijević, Marina, Rat, Milica, Tešević, Vele, Cvetković, Mirjana, "The quantitative structure-retention relationship of the gc-ms profile of yarrow essential oil" in Acta periodica technologica, no. 52 (2021):123-132,
https://doi.org/10.2298/APT2152123A . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Tešević, Vele
AU  - Čabarkapa, Ivana
AU  - Todosijević, Marina
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4209
AB  - A prediction model of retention indices of compounds from the aboveground parts of Satureja kitaibelii essential oil, obtained by hydrodistillation and analysed by Gas Chromatography coupled with Mass Spectrometry (GC-MS), was the aim of this study. The quantitative structure–retention relationship was employed to predict the retention time using five molecular descriptors selected by a genetic algorithm. The selected descriptors were used as inputs of an artificial neural network. Total of 53 experimentally obtained retention indices (log RI) were used to build a prediction model. The selected descriptors were used as inputs of an artificial neural network model, to build a prediction time predictive quantitative structure-retention relationship model. The coefficient of determination for the training cycle was 0.962, indicating that this model could be used for prediction of retention indices for S. kitaibelii essential oil compounds.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - QSRR Model for predicting retention indices of Satureja kitaibelii Wierzb. ex Heuff. essential oil composition
VL  - 154
SP  - 112752
DO  - 10.1016/j.indcrop.2020.112752
ER  - 

@article{
author = "Aćimović, Milica G. and Pezo, Lato and Tešević, Vele and Čabarkapa, Ivana and Todosijević, Marina",
year = "2020",
abstract = "A prediction model of retention indices of compounds from the aboveground parts of Satureja kitaibelii essential oil, obtained by hydrodistillation and analysed by Gas Chromatography coupled with Mass Spectrometry (GC-MS), was the aim of this study. The quantitative structure–retention relationship was employed to predict the retention time using five molecular descriptors selected by a genetic algorithm. The selected descriptors were used as inputs of an artificial neural network. Total of 53 experimentally obtained retention indices (log RI) were used to build a prediction model. The selected descriptors were used as inputs of an artificial neural network model, to build a prediction time predictive quantitative structure-retention relationship model. The coefficient of determination for the training cycle was 0.962, indicating that this model could be used for prediction of retention indices for S. kitaibelii essential oil compounds.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "QSRR Model for predicting retention indices of Satureja kitaibelii Wierzb. ex Heuff. essential oil composition",
volume = "154",
pages = "112752",
doi = "10.1016/j.indcrop.2020.112752"
}

Aćimović, M. G., Pezo, L., Tešević, V., Čabarkapa, I.,& Todosijević, M.. (2020). QSRR Model for predicting retention indices of Satureja kitaibelii Wierzb. ex Heuff. essential oil composition. in Industrial Crops and Products
Elsevier., 154, 112752.
https://doi.org/10.1016/j.indcrop.2020.112752

Aćimović MG, Pezo L, Tešević V, Čabarkapa I, Todosijević M. QSRR Model for predicting retention indices of Satureja kitaibelii Wierzb. ex Heuff. essential oil composition. in Industrial Crops and Products. 2020;154:112752.
doi:10.1016/j.indcrop.2020.112752 .

Aćimović, Milica G., Pezo, Lato, Tešević, Vele, Čabarkapa, Ivana, Todosijević, Marina, "QSRR Model for predicting retention indices of Satureja kitaibelii Wierzb. ex Heuff. essential oil composition" in Industrial Crops and Products, 154 (2020):112752,
https://doi.org/10.1016/j.indcrop.2020.112752 . .

TY  - DATA
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Tešević, Vele
AU  - Čabarkapa, Ivana
AU  - Todosijević, Marina
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4210
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Supplementary data for the article: Aćimović, M.; Pezo, L.; Tešević, V.; Čabarkapa, I.; Todosijević, M. QSRR Model for Predicting Retention Indices of Satureja Kitaibelii Wierzb. Ex Heuff. Essential Oil Composition. Industrial Crops and Products 2020, 154, 112752. https://doi.org/10.1016/j.indcrop.2020.112752
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4210
ER  - 

@misc{
author = "Aćimović, Milica G. and Pezo, Lato and Tešević, Vele and Čabarkapa, Ivana and Todosijević, Marina",
year = "2020",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Supplementary data for the article: Aćimović, M.; Pezo, L.; Tešević, V.; Čabarkapa, I.; Todosijević, M. QSRR Model for Predicting Retention Indices of Satureja Kitaibelii Wierzb. Ex Heuff. Essential Oil Composition. Industrial Crops and Products 2020, 154, 112752. https://doi.org/10.1016/j.indcrop.2020.112752",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4210"
}

Aćimović, M. G., Pezo, L., Tešević, V., Čabarkapa, I.,& Todosijević, M.. (2020). Supplementary data for the article: Aćimović, M.; Pezo, L.; Tešević, V.; Čabarkapa, I.; Todosijević, M. QSRR Model for Predicting Retention Indices of Satureja Kitaibelii Wierzb. Ex Heuff. Essential Oil Composition. Industrial Crops and Products 2020, 154, 112752. https://doi.org/10.1016/j.indcrop.2020.112752. in Industrial Crops and Products
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_4210

Aćimović MG, Pezo L, Tešević V, Čabarkapa I, Todosijević M. Supplementary data for the article: Aćimović, M.; Pezo, L.; Tešević, V.; Čabarkapa, I.; Todosijević, M. QSRR Model for Predicting Retention Indices of Satureja Kitaibelii Wierzb. Ex Heuff. Essential Oil Composition. Industrial Crops and Products 2020, 154, 112752. https://doi.org/10.1016/j.indcrop.2020.112752. in Industrial Crops and Products. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_4210 .

Aćimović, Milica G., Pezo, Lato, Tešević, Vele, Čabarkapa, Ivana, Todosijević, Marina, "Supplementary data for the article: Aćimović, M.; Pezo, L.; Tešević, V.; Čabarkapa, I.; Todosijević, M. QSRR Model for Predicting Retention Indices of Satureja Kitaibelii Wierzb. Ex Heuff. Essential Oil Composition. Industrial Crops and Products 2020, 154, 112752. https://doi.org/10.1016/j.indcrop.2020.112752" in Industrial Crops and Products (2020),
https://hdl.handle.net/21.15107/rcub_cherry_4210 .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Tešević, Vele
AU  - Smiljanić, Katarina
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Kiprovski, Biljana
AU  - Sikora, Vladimir
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5457
AB  - Hydrolates, also referred to as hydrosols, floral or distillate waters, as well as aromat-
ic waters, are produced in the same isolation process with essential oils by steam
distillation. A small amount of essential oil constituents is dissolved in hydrolates
providing specific organoleptic properties and flavor, as well as biological activity
which makes them useful as raw material in many industries. Their popularity is still
on the rise, especially in aromatherapy. The objective in this review is to analyze the
chemical compositions of hydrolates and their corresponding essential oils, as well
as biological activity of hydrolates (antimicrobial, antioxidant and antiinflamatory)
and potential uses, not only in food industry for flavoring, and preservation of fresh-
cut fruits and vegetables, but also as functional (soft) drinks. However, hydrolates
can be used in aromatherapy and cosmetics, as well as in organic agriculture and
aquaculture.
PB  - Leskovac : Univerzitet u Nišu, Tehnološki fakultet
T2  - Advanced technologies
T1  - Hydrolates – By-Products Of Essential Oil Distillation: Chemical Composition, Biological Activity and Potential Uses
VL  - 9
IS  - 2
SP  - 54
EP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5457
ER  - 

@article{
author = "Aćimović, Milica G. and Tešević, Vele and Smiljanić, Katarina and Cvetković, Mirjana and Stanković, Jovana and Kiprovski, Biljana and Sikora, Vladimir",
year = "2020",
abstract = "Hydrolates, also referred to as hydrosols, floral or distillate waters, as well as aromat-
ic waters, are produced in the same isolation process with essential oils by steam
distillation. A small amount of essential oil constituents is dissolved in hydrolates
providing specific organoleptic properties and flavor, as well as biological activity
which makes them useful as raw material in many industries. Their popularity is still
on the rise, especially in aromatherapy. The objective in this review is to analyze the
chemical compositions of hydrolates and their corresponding essential oils, as well
as biological activity of hydrolates (antimicrobial, antioxidant and antiinflamatory)
and potential uses, not only in food industry for flavoring, and preservation of fresh-
cut fruits and vegetables, but also as functional (soft) drinks. However, hydrolates
can be used in aromatherapy and cosmetics, as well as in organic agriculture and
aquaculture.",
publisher = "Leskovac : Univerzitet u Nišu, Tehnološki fakultet",
journal = "Advanced technologies",
title = "Hydrolates – By-Products Of Essential Oil Distillation: Chemical Composition, Biological Activity and Potential Uses",
volume = "9",
number = "2",
pages = "54-70",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5457"
}

Aćimović, M. G., Tešević, V., Smiljanić, K., Cvetković, M., Stanković, J., Kiprovski, B.,& Sikora, V.. (2020). Hydrolates – By-Products Of Essential Oil Distillation: Chemical Composition, Biological Activity and Potential Uses. in Advanced technologies
Leskovac : Univerzitet u Nišu, Tehnološki fakultet., 9(2), 54-70.
https://hdl.handle.net/21.15107/rcub_cherry_5457

Aćimović MG, Tešević V, Smiljanić K, Cvetković M, Stanković J, Kiprovski B, Sikora V. Hydrolates – By-Products Of Essential Oil Distillation: Chemical Composition, Biological Activity and Potential Uses. in Advanced technologies. 2020;9(2):54-70.
https://hdl.handle.net/21.15107/rcub_cherry_5457 .

Aćimović, Milica G., Tešević, Vele, Smiljanić, Katarina, Cvetković, Mirjana, Stanković, Jovana, Kiprovski, Biljana, Sikora, Vladimir, "Hydrolates – By-Products Of Essential Oil Distillation: Chemical Composition, Biological Activity and Potential Uses" in Advanced technologies, 9, no. 2 (2020):54-70,
https://hdl.handle.net/21.15107/rcub_cherry_5457 .