TY  - JOUR
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Kuraica, Milorad M.
AU  - Iskrenović, Predrag
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Perić, Marko
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4569
AB  - Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe3O4 magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe3O4-MNPs were radiolabeled with radionuclide 177Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (> 99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PB  - Springer
T2  - Journal of Inorganic and Organometallic Polymers and Materials
T1  - Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles
VL  - 31
SP  - 4426
EP  - 4433
DO  - 10.1007/s10904-021-02059-1
ER  - 

@article{
author = "Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Kuraica, Milorad M. and Iskrenović, Predrag and Milanović, Zorana and Vranješ-Đurić, Sanja and Perić, Marko",
year = "2021",
abstract = "Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe3O4 magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe3O4-MNPs were radiolabeled with radionuclide 177Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (> 99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
publisher = "Springer",
journal = "Journal of Inorganic and Organometallic Polymers and Materials",
title = "Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles",
volume = "31",
pages = "4426-4433",
doi = "10.1007/s10904-021-02059-1"
}

Radović, M., Mirković, M. D., Nikolić, A. S., Kuraica, M. M., Iskrenović, P., Milanović, Z., Vranješ-Đurić, S.,& Perić, M.. (2021). Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. in Journal of Inorganic and Organometallic Polymers and Materials
Springer., 31, 4426-4433.
https://doi.org/10.1007/s10904-021-02059-1

Radović M, Mirković MD, Nikolić AS, Kuraica MM, Iskrenović P, Milanović Z, Vranješ-Đurić S, Perić M. Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. in Journal of Inorganic and Organometallic Polymers and Materials. 2021;31:4426-4433.
doi:10.1007/s10904-021-02059-1 .

Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Kuraica, Milorad M., Iskrenović, Predrag, Milanović, Zorana, Vranješ-Đurić, Sanja, Perić, Marko, "Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles" in Journal of Inorganic and Organometallic Polymers and Materials, 31 (2021):4426-4433,
https://doi.org/10.1007/s10904-021-02059-1 . .