TY  - JOUR
AU  - Milutinović, Milica
AU  - Nakarada, Đura
AU  - Božunović, Jelena
AU  - Todorović, Miloš
AU  - Gašić, Uroš M.
AU  - Živković, Suzana
AU  - Skorić, Marijana
AU  - Ivković, Đurđa
AU  - Savić, Jelena
AU  - Devrnja, Nina
AU  - Aničić, Neda
AU  - Banjanac, Tijana
AU  - Mojović, Miloš
AU  - Mišić, Danijela
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5896
AB  - The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.
PB  - MDPI
T2  - Antioxidants
T2  - Antioxidants
T1  - Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening
VL  - 12
IS  - 2
SP  - 346
DO  - 10.3390/antiox12020346
ER  - 

@article{
author = "Milutinović, Milica and Nakarada, Đura and Božunović, Jelena and Todorović, Miloš and Gašić, Uroš M. and Živković, Suzana and Skorić, Marijana and Ivković, Đurđa and Savić, Jelena and Devrnja, Nina and Aničić, Neda and Banjanac, Tijana and Mojović, Miloš and Mišić, Danijela",
year = "2023",
abstract = "The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.",
publisher = "MDPI",
journal = "Antioxidants, Antioxidants",
title = "Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening",
volume = "12",
number = "2",
pages = "346",
doi = "10.3390/antiox12020346"
}

Milutinović, M., Nakarada, Đ., Božunović, J., Todorović, M., Gašić, U. M., Živković, S., Skorić, M., Ivković, Đ., Savić, J., Devrnja, N., Aničić, N., Banjanac, T., Mojović, M.,& Mišić, D.. (2023). Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening. in Antioxidants
MDPI., 12(2), 346.
https://doi.org/10.3390/antiox12020346

Milutinović M, Nakarada Đ, Božunović J, Todorović M, Gašić UM, Živković S, Skorić M, Ivković Đ, Savić J, Devrnja N, Aničić N, Banjanac T, Mojović M, Mišić D. Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening. in Antioxidants. 2023;12(2):346.
doi:10.3390/antiox12020346 .

Milutinović, Milica, Nakarada, Đura, Božunović, Jelena, Todorović, Miloš, Gašić, Uroš M., Živković, Suzana, Skorić, Marijana, Ivković, Đurđa, Savić, Jelena, Devrnja, Nina, Aničić, Neda, Banjanac, Tijana, Mojović, Miloš, Mišić, Danijela, "Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening" in Antioxidants, 12, no. 2 (2023):346,
https://doi.org/10.3390/antiox12020346 . .

TY  - JOUR
AU  - Krstajić Pajić, Mila N.
AU  - Dobrota, Ana S.
AU  - Mazare, Anca
AU  - Đurđić, Slađana Z.
AU  - Hwang, Imgon
AU  - Skorodumova, Natalia V.
AU  - Manojlović, Dragan D.
AU  - Vasilić, Rastko
AU  - Pašti, Igor A.
AU  - Schmuki, Patrik
AU  - Lačnjevac, Uroš
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6277
AB  - Efficient cathodes for the hydrogen evolution reaction (HER) in acidic water electrolysis rely on the use of expensive platinum group metals (PGMs). However, to achieve economically viable operation, both the content of PGMs must be reduced and their intrinsically strong H adsorption mitigated. Herein, we show that the surface effects of hydrogenated TiO2 nanotube (TNT) arrays can make osmium, a so far less-explored PGM, a highly active HER electrocatalyst. These defect-rich TiO2 nanostructures provide an interactive scaffold for the galvanic deposition of Os particles with modulated adsorption properties. Through systematic investigations, we identify the synthesis conditions (OsCl3 concentration/temperature/reaction time) that yield a progressive improvement in Os deposition rate and mass loading, thereby decreasing the HER overpotential. At the same time, the Os particles deposited by this procedure remain mainly sub-nanometric and entirely cover the inner tube walls. An optimally balanced Os@TNT composite prepared at 3 mM/55 °C/30 min exhibits a record low overpotential (η) of 61 mV at a current density of 100 mA cm–2, a high mass activity of 20.8 A mgOs–1 at 80 mV, and a stable performance in an acidic medium. Density functional theory calculations indicate the existence of strong interactions between the hydrogenated TiO2 surface and small Os clusters, which may weaken the Os–H* binding strength and thus boost the intrinsic HER activity of Os centers. The results presented in this study offer new directions for the fabrication of cost-effective PGM-based catalysts and a better understanding of the synergistic electronic interactions at the PGM|TiO2 interface.
PB  - American Chemical Society
T2  - ACS Applied Materials & Interfaces
T1  - Activation of Osmium by the Surface Effects of Hydrogenated TiO2 Nanotube Arrays for Enhanced Hydrogen Evolution Reaction Performance
VL  - 15
IS  - 26
SP  - 31459
EP  - 31469
DO  - 10.1021/acsami.3c04498
ER  - 

@article{
author = "Krstajić Pajić, Mila N. and Dobrota, Ana S. and Mazare, Anca and Đurđić, Slađana Z. and Hwang, Imgon and Skorodumova, Natalia V. and Manojlović, Dragan D. and Vasilić, Rastko and Pašti, Igor A. and Schmuki, Patrik and Lačnjevac, Uroš",
year = "2023",
abstract = "Efficient cathodes for the hydrogen evolution reaction (HER) in acidic water electrolysis rely on the use of expensive platinum group metals (PGMs). However, to achieve economically viable operation, both the content of PGMs must be reduced and their intrinsically strong H adsorption mitigated. Herein, we show that the surface effects of hydrogenated TiO2 nanotube (TNT) arrays can make osmium, a so far less-explored PGM, a highly active HER electrocatalyst. These defect-rich TiO2 nanostructures provide an interactive scaffold for the galvanic deposition of Os particles with modulated adsorption properties. Through systematic investigations, we identify the synthesis conditions (OsCl3 concentration/temperature/reaction time) that yield a progressive improvement in Os deposition rate and mass loading, thereby decreasing the HER overpotential. At the same time, the Os particles deposited by this procedure remain mainly sub-nanometric and entirely cover the inner tube walls. An optimally balanced Os@TNT composite prepared at 3 mM/55 °C/30 min exhibits a record low overpotential (η) of 61 mV at a current density of 100 mA cm–2, a high mass activity of 20.8 A mgOs–1 at 80 mV, and a stable performance in an acidic medium. Density functional theory calculations indicate the existence of strong interactions between the hydrogenated TiO2 surface and small Os clusters, which may weaken the Os–H* binding strength and thus boost the intrinsic HER activity of Os centers. The results presented in this study offer new directions for the fabrication of cost-effective PGM-based catalysts and a better understanding of the synergistic electronic interactions at the PGM|TiO2 interface.",
publisher = "American Chemical Society",
journal = "ACS Applied Materials & Interfaces",
title = "Activation of Osmium by the Surface Effects of Hydrogenated TiO2 Nanotube Arrays for Enhanced Hydrogen Evolution Reaction Performance",
volume = "15",
number = "26",
pages = "31459-31469",
doi = "10.1021/acsami.3c04498"
}

Krstajić Pajić, M. N., Dobrota, A. S., Mazare, A., Đurđić, S. Z., Hwang, I., Skorodumova, N. V., Manojlović, D. D., Vasilić, R., Pašti, I. A., Schmuki, P.,& Lačnjevac, U.. (2023). Activation of Osmium by the Surface Effects of Hydrogenated TiO2 Nanotube Arrays for Enhanced Hydrogen Evolution Reaction Performance. in ACS Applied Materials & Interfaces
American Chemical Society., 15(26), 31459-31469.
https://doi.org/10.1021/acsami.3c04498

Krstajić Pajić MN, Dobrota AS, Mazare A, Đurđić SZ, Hwang I, Skorodumova NV, Manojlović DD, Vasilić R, Pašti IA, Schmuki P, Lačnjevac U. Activation of Osmium by the Surface Effects of Hydrogenated TiO2 Nanotube Arrays for Enhanced Hydrogen Evolution Reaction Performance. in ACS Applied Materials & Interfaces. 2023;15(26):31459-31469.
doi:10.1021/acsami.3c04498 .

Krstajić Pajić, Mila N., Dobrota, Ana S., Mazare, Anca, Đurđić, Slađana Z., Hwang, Imgon, Skorodumova, Natalia V., Manojlović, Dragan D., Vasilić, Rastko, Pašti, Igor A., Schmuki, Patrik, Lačnjevac, Uroš, "Activation of Osmium by the Surface Effects of Hydrogenated TiO2 Nanotube Arrays for Enhanced Hydrogen Evolution Reaction Performance" in ACS Applied Materials & Interfaces, 15, no. 26 (2023):31459-31469,
https://doi.org/10.1021/acsami.3c04498 . .

TY  - JOUR
AU  - Ćeranić, Katarina
AU  - Milovanović, Branislav
AU  - Petković, Milena
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6395
AB  - Metal ion detection rests on host–guest recognition. We propose a theoretical protocol for designing an optimal trap for a desired metal cation. A host for magnesium ions was sought for among derivatives of crown ethers 12-crown-4, 15-crown-5, and 18-crown-6. Mg–crown complexes and their hydrated counterparts with water molecules bound to the cation were optimized using density functional theory. Based on specific geometric criteria, Interacting quantum atoms analysis and density functional theory-based molecular dynamics of Mg–crown complexes immersed in water, crown ethers for optimal accommodation of Mg2+ in aqueous solution were identified. Selectivity of the chosen crowns towards Na+, K+, and Ca2+ ions is addressed.
PB  - Royal Society of Chemistry
T2  - Physical Chemistry Chemical Physics
T1  - Density functional theory study of crown ether–magnesium complexes: from a solvated ion to an ion trap
VL  - 25
IS  - 47
SP  - 32656
EP  - 32665
DO  - 10.1039/D3CP03991A
ER  - 

@article{
author = "Ćeranić, Katarina and Milovanović, Branislav and Petković, Milena",
year = "2023",
abstract = "Metal ion detection rests on host–guest recognition. We propose a theoretical protocol for designing an optimal trap for a desired metal cation. A host for magnesium ions was sought for among derivatives of crown ethers 12-crown-4, 15-crown-5, and 18-crown-6. Mg–crown complexes and their hydrated counterparts with water molecules bound to the cation were optimized using density functional theory. Based on specific geometric criteria, Interacting quantum atoms analysis and density functional theory-based molecular dynamics of Mg–crown complexes immersed in water, crown ethers for optimal accommodation of Mg2+ in aqueous solution were identified. Selectivity of the chosen crowns towards Na+, K+, and Ca2+ ions is addressed.",
publisher = "Royal Society of Chemistry",
journal = "Physical Chemistry Chemical Physics",
title = "Density functional theory study of crown ether–magnesium complexes: from a solvated ion to an ion trap",
volume = "25",
number = "47",
pages = "32656-32665",
doi = "10.1039/D3CP03991A"
}

Ćeranić, K., Milovanović, B.,& Petković, M.. (2023). Density functional theory study of crown ether–magnesium complexes: from a solvated ion to an ion trap. in Physical Chemistry Chemical Physics
Royal Society of Chemistry., 25(47), 32656-32665.
https://doi.org/10.1039/D3CP03991A

Ćeranić K, Milovanović B, Petković M. Density functional theory study of crown ether–magnesium complexes: from a solvated ion to an ion trap. in Physical Chemistry Chemical Physics. 2023;25(47):32656-32665.
doi:10.1039/D3CP03991A .

Ćeranić, Katarina, Milovanović, Branislav, Petković, Milena, "Density functional theory study of crown ether–magnesium complexes: from a solvated ion to an ion trap" in Physical Chemistry Chemical Physics, 25, no. 47 (2023):32656-32665,
https://doi.org/10.1039/D3CP03991A . .

TY  - JOUR
AU  - Jaćimović, Simona
AU  - Kiprovski, Biljana
AU  - Ristivojević, Petar
AU  - Dimić, Dušan
AU  - Nakarada, Đura
AU  - Dojčinović, Biljana P.
AU  - Sikora, Vladimir
AU  - Teslić, Nemanja
AU  - Pantelić, Nebojša Đ.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6325
AB  - Sorghum grain (Sorghum bicolor L. Moench) is a gluten-free cereal with excellent nutritional value and is a good source of antioxidants, including polyphenols, as well as minerals with proven health benefits. Herein, the phenolic composition, elemental profile, and antioxidant activity of sixteen food-grade sorghum grains (S1–S16) grown under agroecological conditions in Serbia were determined. Nine phenolic compounds characteristic of sorghum grains, such as luteolinidin, 5-methoxyluteolinidin, luteolidin derivative, luteolidin glucoside, apigeninidin, 7-methoxyapigeninidin, apigeninidin glucoside, and cyanidin derivative, were quantified. The antioxidant potential of the analyzed sorghum grains was evaluated by UV/Vis (DPPH, ABTS, and FRAP) and Electron Paramagnetic Resonance spectroscopy (hydroxyl and ascorbyl radical scavenging assays). The content of macro- and microelements was determined by Inductively Coupled Plasma Optical Emission spectroscopy. Theoretical daily intakes of selected major and trace elements were assessed and compared with the Recommended Daily Allowance or Adequate Intake. Sample S8 had the highest amount of phenolic compounds, while S4, S6, and S8 exhibited the strongest antioxidative potential. The sorghum studied could completely satisfy the daily needs of macro- (K, Mg, and P) and microelements (Se, Zn, Fe). Pattern recognition techniques confirmed the discrimination of samples based on phenolic profile and elemental analysis and recognized the main markers responsible for differences between the investigated samples. The reaction between hydroxyl radicals and luteolinidin/apigeninidin was investigated by Density Functional Theory and thermodynamically preferred mechanism was determined.
T2  - Antioxidants
T2  - Antioxidants
T1  - Chemical Composition, Antioxidant Potential, and Nutritional Evaluation of Cultivated Sorghum Grains: A Combined Experimental, Theoretical, and Multivariate Analysis
VL  - 12
IS  - 8
SP  - 1485
DO  - 10.3390/antiox12081485
ER  - 

@article{
author = "Jaćimović, Simona and Kiprovski, Biljana and Ristivojević, Petar and Dimić, Dušan and Nakarada, Đura and Dojčinović, Biljana P. and Sikora, Vladimir and Teslić, Nemanja and Pantelić, Nebojša Đ.",
year = "2023",
abstract = "Sorghum grain (Sorghum bicolor L. Moench) is a gluten-free cereal with excellent nutritional value and is a good source of antioxidants, including polyphenols, as well as minerals with proven health benefits. Herein, the phenolic composition, elemental profile, and antioxidant activity of sixteen food-grade sorghum grains (S1–S16) grown under agroecological conditions in Serbia were determined. Nine phenolic compounds characteristic of sorghum grains, such as luteolinidin, 5-methoxyluteolinidin, luteolidin derivative, luteolidin glucoside, apigeninidin, 7-methoxyapigeninidin, apigeninidin glucoside, and cyanidin derivative, were quantified. The antioxidant potential of the analyzed sorghum grains was evaluated by UV/Vis (DPPH, ABTS, and FRAP) and Electron Paramagnetic Resonance spectroscopy (hydroxyl and ascorbyl radical scavenging assays). The content of macro- and microelements was determined by Inductively Coupled Plasma Optical Emission spectroscopy. Theoretical daily intakes of selected major and trace elements were assessed and compared with the Recommended Daily Allowance or Adequate Intake. Sample S8 had the highest amount of phenolic compounds, while S4, S6, and S8 exhibited the strongest antioxidative potential. The sorghum studied could completely satisfy the daily needs of macro- (K, Mg, and P) and microelements (Se, Zn, Fe). Pattern recognition techniques confirmed the discrimination of samples based on phenolic profile and elemental analysis and recognized the main markers responsible for differences between the investigated samples. The reaction between hydroxyl radicals and luteolinidin/apigeninidin was investigated by Density Functional Theory and thermodynamically preferred mechanism was determined.",
journal = "Antioxidants, Antioxidants",
title = "Chemical Composition, Antioxidant Potential, and Nutritional Evaluation of Cultivated Sorghum Grains: A Combined Experimental, Theoretical, and Multivariate Analysis",
volume = "12",
number = "8",
pages = "1485",
doi = "10.3390/antiox12081485"
}

Jaćimović, S., Kiprovski, B., Ristivojević, P., Dimić, D., Nakarada, Đ., Dojčinović, B. P., Sikora, V., Teslić, N.,& Pantelić, N. Đ.. (2023). Chemical Composition, Antioxidant Potential, and Nutritional Evaluation of Cultivated Sorghum Grains: A Combined Experimental, Theoretical, and Multivariate Analysis. in Antioxidants, 12(8), 1485.
https://doi.org/10.3390/antiox12081485

Jaćimović S, Kiprovski B, Ristivojević P, Dimić D, Nakarada Đ, Dojčinović BP, Sikora V, Teslić N, Pantelić NĐ. Chemical Composition, Antioxidant Potential, and Nutritional Evaluation of Cultivated Sorghum Grains: A Combined Experimental, Theoretical, and Multivariate Analysis. in Antioxidants. 2023;12(8):1485.
doi:10.3390/antiox12081485 .

Jaćimović, Simona, Kiprovski, Biljana, Ristivojević, Petar, Dimić, Dušan, Nakarada, Đura, Dojčinović, Biljana P., Sikora, Vladimir, Teslić, Nemanja, Pantelić, Nebojša Đ., "Chemical Composition, Antioxidant Potential, and Nutritional Evaluation of Cultivated Sorghum Grains: A Combined Experimental, Theoretical, and Multivariate Analysis" in Antioxidants, 12, no. 8 (2023):1485,
https://doi.org/10.3390/antiox12081485 . .

TY  - JOUR
AU  - Korać Jačić, Jelena
AU  - Dimitrijević, Milena S.
AU  - Bajuk-Bogdanović, Danica V.
AU  - Stanković, Dalibor
AU  - Savić, Slađana D.
AU  - Spasojević, Ivan B.
AU  - MIlenković, Milica R.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6043
AB  - The interactions of drugs with iron are of interest in relation to the potential effects of iron-rich foods and iron supplements on sorption and bioavailability. Doxycycline (DOX), a member of the tetracycline class of broad-spectrum antibiotics, is frequently administered by oral route. In the digestive tract, DOX can be exposed to iron at different pH values (stomach pH 1.5–4, duodenum pH 5–6, distal jejunum and ileum pH 7–8). In relation to this, we analyzed the impact of pH on Fe3+-DOX complex formation. The optimal conditions for Fe3+-DOX complex formation are pH = 4 and [Fe3+]/[DOX] = 6 molar ratio. HESI-MS showed that Fe3+-DOX complex has 1:1 stoichiometry. Raman spectra of Fe3+-DOX complex indicate the presence of two Fe3+-binding sites in DOX structure: tricarbonylamide group of ring A and phenolic-diketone oxygens of BCD rings. The Fe3+-DOX complex formed at pH = 4 is less susceptible to oxidation than DOX at this pH. The increase of pH induces the decomposition of Fe3+-DOX complex without oxidative degradation of DOX. The pH dependence of Fe3+-DOX complex formation may promote unwanted effects of DOX, impeding the absorption that mainly takes place in duodenum. This could further result in higher concentrations in the digestive tract and to pronounced impact on gut microbiota.
PB  - Springer
T2  - Journal of Biological Inorganic Chemistry
T1  - The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability
VL  - 28
SP  - 679
EP  - 687
DO  - 10.1007/s00775-023-02018-w
ER  - 

@article{
author = "Korać Jačić, Jelena and Dimitrijević, Milena S. and Bajuk-Bogdanović, Danica V. and Stanković, Dalibor and Savić, Slađana D. and Spasojević, Ivan B. and MIlenković, Milica R.",
year = "2023",
abstract = "The interactions of drugs with iron are of interest in relation to the potential effects of iron-rich foods and iron supplements on sorption and bioavailability. Doxycycline (DOX), a member of the tetracycline class of broad-spectrum antibiotics, is frequently administered by oral route. In the digestive tract, DOX can be exposed to iron at different pH values (stomach pH 1.5–4, duodenum pH 5–6, distal jejunum and ileum pH 7–8). In relation to this, we analyzed the impact of pH on Fe3+-DOX complex formation. The optimal conditions for Fe3+-DOX complex formation are pH = 4 and [Fe3+]/[DOX] = 6 molar ratio. HESI-MS showed that Fe3+-DOX complex has 1:1 stoichiometry. Raman spectra of Fe3+-DOX complex indicate the presence of two Fe3+-binding sites in DOX structure: tricarbonylamide group of ring A and phenolic-diketone oxygens of BCD rings. The Fe3+-DOX complex formed at pH = 4 is less susceptible to oxidation than DOX at this pH. The increase of pH induces the decomposition of Fe3+-DOX complex without oxidative degradation of DOX. The pH dependence of Fe3+-DOX complex formation may promote unwanted effects of DOX, impeding the absorption that mainly takes place in duodenum. This could further result in higher concentrations in the digestive tract and to pronounced impact on gut microbiota.",
publisher = "Springer",
journal = "Journal of Biological Inorganic Chemistry",
title = "The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability",
volume = "28",
pages = "679-687",
doi = "10.1007/s00775-023-02018-w"
}

Korać Jačić, J., Dimitrijević, M. S., Bajuk-Bogdanović, D. V., Stanković, D., Savić, S. D., Spasojević, I. B.,& MIlenković, M. R.. (2023). The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability. in Journal of Biological Inorganic Chemistry
Springer., 28, 679-687.
https://doi.org/10.1007/s00775-023-02018-w

Korać Jačić J, Dimitrijević MS, Bajuk-Bogdanović DV, Stanković D, Savić SD, Spasojević IB, MIlenković MR. The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability. in Journal of Biological Inorganic Chemistry. 2023;28:679-687.
doi:10.1007/s00775-023-02018-w .

Korać Jačić, Jelena, Dimitrijević, Milena S., Bajuk-Bogdanović, Danica V., Stanković, Dalibor, Savić, Slađana D., Spasojević, Ivan B., MIlenković, Milica R., "The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability" in Journal of Biological Inorganic Chemistry, 28 (2023):679-687,
https://doi.org/10.1007/s00775-023-02018-w . .

TY  - JOUR
AU  - Korać Jačić, Jelena
AU  - Dimitrijević, Milena S.
AU  - Bajuk-Bogdanović, Danica V.
AU  - Stanković, Dalibor
AU  - Savić, Slađana D.
AU  - Spasojević, Ivan B.
AU  - MIlenković, Milica R.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6044
AB  - The interactions of drugs with iron are of interest in relation to the potential effects of iron-rich foods and iron supplements on sorption and bioavailability. Doxycycline (DOX), a member of the tetracycline class of broad-spectrum antibiotics, is frequently administered by oral route. In the digestive tract, DOX can be exposed to iron at different pH values (stomach pH 1.5–4, duodenum pH 5–6, distal jejunum and ileum pH 7–8). In relation to this, we analyzed the impact of pH on Fe3+-DOX complex formation. The optimal conditions for Fe3+-DOX complex formation are pH = 4 and [Fe3+]/[DOX] = 6 molar ratio. HESI-MS showed that Fe3+-DOX complex has 1:1 stoichiometry. Raman spectra of Fe3+-DOX complex indicate the presence of two Fe3+-binding sites in DOX structure: tricarbonylamide group of ring A and phenolic-diketone oxygens of BCD rings. The Fe3+-DOX complex formed at pH = 4 is less susceptible to oxidation than DOX at this pH. The increase of pH induces the decomposition of Fe3+-DOX complex without oxidative degradation of DOX. The pH dependence of Fe3+-DOX complex formation may promote unwanted effects of DOX, impeding the absorption that mainly takes place in duodenum. This could further result in higher concentrations in the digestive tract and to pronounced impact on gut microbiota.
PB  - Springer
T2  - Journal of Biological Inorganic Chemistry
T1  - The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability
VL  - 28
SP  - 679
EP  - 687
DO  - 10.1007/s00775-023-02018-w
ER  - 

@article{
author = "Korać Jačić, Jelena and Dimitrijević, Milena S. and Bajuk-Bogdanović, Danica V. and Stanković, Dalibor and Savić, Slađana D. and Spasojević, Ivan B. and MIlenković, Milica R.",
year = "2023",
abstract = "The interactions of drugs with iron are of interest in relation to the potential effects of iron-rich foods and iron supplements on sorption and bioavailability. Doxycycline (DOX), a member of the tetracycline class of broad-spectrum antibiotics, is frequently administered by oral route. In the digestive tract, DOX can be exposed to iron at different pH values (stomach pH 1.5–4, duodenum pH 5–6, distal jejunum and ileum pH 7–8). In relation to this, we analyzed the impact of pH on Fe3+-DOX complex formation. The optimal conditions for Fe3+-DOX complex formation are pH = 4 and [Fe3+]/[DOX] = 6 molar ratio. HESI-MS showed that Fe3+-DOX complex has 1:1 stoichiometry. Raman spectra of Fe3+-DOX complex indicate the presence of two Fe3+-binding sites in DOX structure: tricarbonylamide group of ring A and phenolic-diketone oxygens of BCD rings. The Fe3+-DOX complex formed at pH = 4 is less susceptible to oxidation than DOX at this pH. The increase of pH induces the decomposition of Fe3+-DOX complex without oxidative degradation of DOX. The pH dependence of Fe3+-DOX complex formation may promote unwanted effects of DOX, impeding the absorption that mainly takes place in duodenum. This could further result in higher concentrations in the digestive tract and to pronounced impact on gut microbiota.",
publisher = "Springer",
journal = "Journal of Biological Inorganic Chemistry",
title = "The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability",
volume = "28",
pages = "679-687",
doi = "10.1007/s00775-023-02018-w"
}

Korać Jačić, J., Dimitrijević, M. S., Bajuk-Bogdanović, D. V., Stanković, D., Savić, S. D., Spasojević, I. B.,& MIlenković, M. R.. (2023). The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability. in Journal of Biological Inorganic Chemistry
Springer., 28, 679-687.
https://doi.org/10.1007/s00775-023-02018-w

Korać Jačić J, Dimitrijević MS, Bajuk-Bogdanović DV, Stanković D, Savić SD, Spasojević IB, MIlenković MR. The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability. in Journal of Biological Inorganic Chemistry. 2023;28:679-687.
doi:10.1007/s00775-023-02018-w .

Korać Jačić, Jelena, Dimitrijević, Milena S., Bajuk-Bogdanović, Danica V., Stanković, Dalibor, Savić, Slađana D., Spasojević, Ivan B., MIlenković, Milica R., "The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability" in Journal of Biological Inorganic Chemistry, 28 (2023):679-687,
https://doi.org/10.1007/s00775-023-02018-w . .

TY  - JOUR
AU  - Milikić, Jadranka
AU  - Knežević, Sara
AU  - Ognjanović, Miloš
AU  - Stanković, Dalibor
AU  - Rakočević, Lazar
AU  - Šljukić, Biljana
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6250
AB  - Porous cobalt (III) oxide (Co3O4) and mixed cobalt (III) oxide - tin oxide (Co3O4/SnO2) were prepared by a novel template-based hydrothermal method resulting in their spherical morphology as confirmed by thorough physico-chemical characterisation. Two oxides were systematically examined as bifunctional electrocatalysts for oxygen reduction (ORR) and evolution (OER) reaction in alkaline media by voltammetry with rotating disk electrode, electrochemical impedance spectroscopy, and chronoamperometry. Low-cost Co3O4 and Co3O4/SnO2 electrocatalysts showed excellent ORR performance with low onset and half-wave potential, low Tafel slope, and the number of exchange electrons near 4, comparable to the commercial Pt/C electrocatalyst. Low OER onset potential of 1.52 and 1.57 V was observed for Co3O4 and Co3O4/SnO2, respectively, with low charge transfer resistance under anodic polarization conditions. Finally, to test bifunctional activity and durability of the two electrocatalyst, switch OER/ORR test was carried out.
PB  - Elsevier
T2  - International Journal of Hydrogen EnergyInternational Journal of Hydrogen Energy
T1  - Template-based synthesis of Co3O4 and Co3O4/SnO2 bifunctional catalysts with enhanced electrocatalytic properties for reversible oxygen evolution and reduction reaction
VL  - 48
IS  - 71
SP  - 27568
EP  - 27581
DO  - 10.1016/j.ijhydene.2023.03.433
ER  - 

@article{
author = "Milikić, Jadranka and Knežević, Sara and Ognjanović, Miloš and Stanković, Dalibor and Rakočević, Lazar and Šljukić, Biljana",
year = "2023",
abstract = "Porous cobalt (III) oxide (Co3O4) and mixed cobalt (III) oxide - tin oxide (Co3O4/SnO2) were prepared by a novel template-based hydrothermal method resulting in their spherical morphology as confirmed by thorough physico-chemical characterisation. Two oxides were systematically examined as bifunctional electrocatalysts for oxygen reduction (ORR) and evolution (OER) reaction in alkaline media by voltammetry with rotating disk electrode, electrochemical impedance spectroscopy, and chronoamperometry. Low-cost Co3O4 and Co3O4/SnO2 electrocatalysts showed excellent ORR performance with low onset and half-wave potential, low Tafel slope, and the number of exchange electrons near 4, comparable to the commercial Pt/C electrocatalyst. Low OER onset potential of 1.52 and 1.57 V was observed for Co3O4 and Co3O4/SnO2, respectively, with low charge transfer resistance under anodic polarization conditions. Finally, to test bifunctional activity and durability of the two electrocatalyst, switch OER/ORR test was carried out.",
publisher = "Elsevier",
journal = "International Journal of Hydrogen EnergyInternational Journal of Hydrogen Energy",
title = "Template-based synthesis of Co3O4 and Co3O4/SnO2 bifunctional catalysts with enhanced electrocatalytic properties for reversible oxygen evolution and reduction reaction",
volume = "48",
number = "71",
pages = "27568-27581",
doi = "10.1016/j.ijhydene.2023.03.433"
}

Milikić, J., Knežević, S., Ognjanović, M., Stanković, D., Rakočević, L.,& Šljukić, B.. (2023). Template-based synthesis of Co3O4 and Co3O4/SnO2 bifunctional catalysts with enhanced electrocatalytic properties for reversible oxygen evolution and reduction reaction. in International Journal of Hydrogen EnergyInternational Journal of Hydrogen Energy
Elsevier., 48(71), 27568-27581.
https://doi.org/10.1016/j.ijhydene.2023.03.433

Milikić J, Knežević S, Ognjanović M, Stanković D, Rakočević L, Šljukić B. Template-based synthesis of Co3O4 and Co3O4/SnO2 bifunctional catalysts with enhanced electrocatalytic properties for reversible oxygen evolution and reduction reaction. in International Journal of Hydrogen EnergyInternational Journal of Hydrogen Energy. 2023;48(71):27568-27581.
doi:10.1016/j.ijhydene.2023.03.433 .

Milikić, Jadranka, Knežević, Sara, Ognjanović, Miloš, Stanković, Dalibor, Rakočević, Lazar, Šljukić, Biljana, "Template-based synthesis of Co3O4 and Co3O4/SnO2 bifunctional catalysts with enhanced electrocatalytic properties for reversible oxygen evolution and reduction reaction" in International Journal of Hydrogen EnergyInternational Journal of Hydrogen Energy, 48, no. 71 (2023):27568-27581,
https://doi.org/10.1016/j.ijhydene.2023.03.433 . .

TY  - JOUR
AU  - Korać Jačić, Jelena
AU  - Bajuk-Bogdanović, Danica
AU  - Savić, Slađana D.
AU  - Božić Cvijan, Bojana
AU  - Spasojević, Milica
AU  - MIlenković, Milica R.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5881
AB  - Hydralazine (HL), a frequently prescribed oral antihypertensive drug, shows redox interactions with transition metals such as copper that are not fully understood. Copper may be present at high concentrations in the digestive tract and can affect oral drugs. An important parameter for such interactions is pH, which changes from acidic in the gastric juice to neutral pH in intestines. In this study, we examined interactions of HL with Cu2+ ions in conditions that mimic pH shift in the digestive tract using UV–Vis, Raman and EPR spectroscopy, cyclic voltammetry and oximetry. In the acidic solution, Cu2+ formed a stable mononuclear complex with two bidentate coordinated HL molecules. On the other hand, at neutral pH, Cu2+ initiated oxidation and degradation of HL. The degradation was more rapid in the HL-Cu2+ system that was initially prepared at acidic pH and then shifted to neutral pH. The formation of the complex at acidic pH increases the availability of Cu2+ for redox reactions after the shift to neutral pH at which Cu2+ is poorly soluble. These results imply that the change of pH along the digestive tract may promote HL degradation by allowing the formation of the complex at gastric pH which makes Cu2+ available for subsequent oxidation of HL at neutral pH.
PB  - Elsevier
T2  - Journal of Inorganic Biochemistry
T1  - Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH
VL  - 243
SP  - 112181
DO  - 10.1016/j.jinorgbio.2023.112181
ER  - 

@article{
author = "Korać Jačić, Jelena and Bajuk-Bogdanović, Danica and Savić, Slađana D. and Božić Cvijan, Bojana and Spasojević, Milica and MIlenković, Milica R.",
year = "2023",
abstract = "Hydralazine (HL), a frequently prescribed oral antihypertensive drug, shows redox interactions with transition metals such as copper that are not fully understood. Copper may be present at high concentrations in the digestive tract and can affect oral drugs. An important parameter for such interactions is pH, which changes from acidic in the gastric juice to neutral pH in intestines. In this study, we examined interactions of HL with Cu2+ ions in conditions that mimic pH shift in the digestive tract using UV–Vis, Raman and EPR spectroscopy, cyclic voltammetry and oximetry. In the acidic solution, Cu2+ formed a stable mononuclear complex with two bidentate coordinated HL molecules. On the other hand, at neutral pH, Cu2+ initiated oxidation and degradation of HL. The degradation was more rapid in the HL-Cu2+ system that was initially prepared at acidic pH and then shifted to neutral pH. The formation of the complex at acidic pH increases the availability of Cu2+ for redox reactions after the shift to neutral pH at which Cu2+ is poorly soluble. These results imply that the change of pH along the digestive tract may promote HL degradation by allowing the formation of the complex at gastric pH which makes Cu2+ available for subsequent oxidation of HL at neutral pH.",
publisher = "Elsevier",
journal = "Journal of Inorganic Biochemistry",
title = "Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH",
volume = "243",
pages = "112181",
doi = "10.1016/j.jinorgbio.2023.112181"
}

Korać Jačić, J., Bajuk-Bogdanović, D., Savić, S. D., Božić Cvijan, B., Spasojević, M.,& MIlenković, M. R.. (2023). Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH. in Journal of Inorganic Biochemistry
Elsevier., 243, 112181.
https://doi.org/10.1016/j.jinorgbio.2023.112181

Korać Jačić J, Bajuk-Bogdanović D, Savić SD, Božić Cvijan B, Spasojević M, MIlenković MR. Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH. in Journal of Inorganic Biochemistry. 2023;243:112181.
doi:10.1016/j.jinorgbio.2023.112181 .

Korać Jačić, Jelena, Bajuk-Bogdanović, Danica, Savić, Slađana D., Božić Cvijan, Bojana, Spasojević, Milica, MIlenković, Milica R., "Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH" in Journal of Inorganic Biochemistry, 243 (2023):112181,
https://doi.org/10.1016/j.jinorgbio.2023.112181 . .

TY  - JOUR
AU  - Korać Jačić, Jelena
AU  - Bajuk-Bogdanović, Danica
AU  - Savić, Slađana D.
AU  - Božić Cvijan, Bojana
AU  - Spasojević, Milica
AU  - MIlenković, Milica R.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5882
AB  - Hydralazine (HL), a frequently prescribed oral antihypertensive drug, shows redox interactions with transition metals such as copper that are not fully understood. Copper may be present at high concentrations in the digestive tract and can affect oral drugs. An important parameter for such interactions is pH, which changes from acidic in the gastric juice to neutral pH in intestines. In this study, we examined interactions of HL with Cu2+ ions in conditions that mimic pH shift in the digestive tract using UV–Vis, Raman and EPR spectroscopy, cyclic voltammetry and oximetry. In the acidic solution, Cu2+ formed a stable mononuclear complex with two bidentate coordinated HL molecules. On the other hand, at neutral pH, Cu2+ initiated oxidation and degradation of HL. The degradation was more rapid in the HL-Cu2+ system that was initially prepared at acidic pH and then shifted to neutral pH. The formation of the complex at acidic pH increases the availability of Cu2+ for redox reactions after the shift to neutral pH at which Cu2+ is poorly soluble. These results imply that the change of pH along the digestive tract may promote HL degradation by allowing the formation of the complex at gastric pH which makes Cu2+ available for subsequent oxidation of HL at neutral pH.
PB  - Elsevier
T2  - Journal of Inorganic Biochemistry
T1  - Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH
VL  - 243
SP  - 112181
DO  - 10.1016/j.jinorgbio.2023.112181
ER  - 

@article{
author = "Korać Jačić, Jelena and Bajuk-Bogdanović, Danica and Savić, Slađana D. and Božić Cvijan, Bojana and Spasojević, Milica and MIlenković, Milica R.",
year = "2023",
abstract = "Hydralazine (HL), a frequently prescribed oral antihypertensive drug, shows redox interactions with transition metals such as copper that are not fully understood. Copper may be present at high concentrations in the digestive tract and can affect oral drugs. An important parameter for such interactions is pH, which changes from acidic in the gastric juice to neutral pH in intestines. In this study, we examined interactions of HL with Cu2+ ions in conditions that mimic pH shift in the digestive tract using UV–Vis, Raman and EPR spectroscopy, cyclic voltammetry and oximetry. In the acidic solution, Cu2+ formed a stable mononuclear complex with two bidentate coordinated HL molecules. On the other hand, at neutral pH, Cu2+ initiated oxidation and degradation of HL. The degradation was more rapid in the HL-Cu2+ system that was initially prepared at acidic pH and then shifted to neutral pH. The formation of the complex at acidic pH increases the availability of Cu2+ for redox reactions after the shift to neutral pH at which Cu2+ is poorly soluble. These results imply that the change of pH along the digestive tract may promote HL degradation by allowing the formation of the complex at gastric pH which makes Cu2+ available for subsequent oxidation of HL at neutral pH.",
publisher = "Elsevier",
journal = "Journal of Inorganic Biochemistry",
title = "Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH",
volume = "243",
pages = "112181",
doi = "10.1016/j.jinorgbio.2023.112181"
}

Korać Jačić, J., Bajuk-Bogdanović, D., Savić, S. D., Božić Cvijan, B., Spasojević, M.,& MIlenković, M. R.. (2023). Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH. in Journal of Inorganic Biochemistry
Elsevier., 243, 112181.
https://doi.org/10.1016/j.jinorgbio.2023.112181

Korać Jačić J, Bajuk-Bogdanović D, Savić SD, Božić Cvijan B, Spasojević M, MIlenković MR. Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH. in Journal of Inorganic Biochemistry. 2023;243:112181.
doi:10.1016/j.jinorgbio.2023.112181 .

Korać Jačić, Jelena, Bajuk-Bogdanović, Danica, Savić, Slađana D., Božić Cvijan, Bojana, Spasojević, Milica, MIlenković, Milica R., "Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH" in Journal of Inorganic Biochemistry, 243 (2023):112181,
https://doi.org/10.1016/j.jinorgbio.2023.112181 . .

TY  - JOUR
AU  - Bartolić, Dragana
AU  - Mojović, Miloš
AU  - Prokopijević, Miloš
AU  - Đikanović, Daniela
AU  - Kalauzi, Aleksandar
AU  - Mutavdžić, Dragosav
AU  - Baošić, Rada
AU  - Radotić, Ksenija
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5268
AB  - Aflatoxin B1 (AFB1), is a naturally hazardous environmental contaminant, contained mainly in various cereal seeds. The maize (Zea mays L.) seeds containing various levels of the AFB1 was investigated using optical and electron paramagnetic resonance spectroscopies. The changes of lignin content and organic free radicals as indicators of the seeds' defense response to the AFB1-stressor were estimated, in the seeds' inner and outer fractions. The lignin content was determined using the Acetyl Bromide method. No correlation was found between the lignin content and the AFB1 concentration in the inner fraction (R of 0.030, p = 0.943), while a significant positive linear correlation (R of 0.9923, p= 0.00005) between the lignin content and the AFB1 concentration in the outer fraction was obtained. Employing electron paramagnetic resonance (EPR) spectroscopy, the different response of the fractions was observed, regarding the content of free radicals with increasing AFB1 concentrations. In addition, front-face fluorescence spectroscopy in combination with the deconvolution showed a positive linear correlation between the ratio of the green and blue spectral emission components (C4/C2) area and the AFB1 concentration in the outer fraction. Thus lignin content and the (C4/C2) area ratio may be reliable indicators for the screening of lignin changes related to the level of AFB1 in the seeds.
PB  - Wiley
T2  - Journal of the Science of Food and Agriculture
T1  - Lignin and organic free radicals in maize (Zea mays  L.) seeds in response to aflatoxin B1 contamination: an optical and EPR spectroscopic study
VL  - 102
IS  - 6
SP  - 2500
EP  - 2505
DO  - 10.1002/jsfa.11591
ER  - 

@article{
author = "Bartolić, Dragana and Mojović, Miloš and Prokopijević, Miloš and Đikanović, Daniela and Kalauzi, Aleksandar and Mutavdžić, Dragosav and Baošić, Rada and Radotić, Ksenija",
year = "2022",
abstract = "Aflatoxin B1 (AFB1), is a naturally hazardous environmental contaminant, contained mainly in various cereal seeds. The maize (Zea mays L.) seeds containing various levels of the AFB1 was investigated using optical and electron paramagnetic resonance spectroscopies. The changes of lignin content and organic free radicals as indicators of the seeds' defense response to the AFB1-stressor were estimated, in the seeds' inner and outer fractions. The lignin content was determined using the Acetyl Bromide method. No correlation was found between the lignin content and the AFB1 concentration in the inner fraction (R of 0.030, p = 0.943), while a significant positive linear correlation (R of 0.9923, p= 0.00005) between the lignin content and the AFB1 concentration in the outer fraction was obtained. Employing electron paramagnetic resonance (EPR) spectroscopy, the different response of the fractions was observed, regarding the content of free radicals with increasing AFB1 concentrations. In addition, front-face fluorescence spectroscopy in combination with the deconvolution showed a positive linear correlation between the ratio of the green and blue spectral emission components (C4/C2) area and the AFB1 concentration in the outer fraction. Thus lignin content and the (C4/C2) area ratio may be reliable indicators for the screening of lignin changes related to the level of AFB1 in the seeds.",
publisher = "Wiley",
journal = "Journal of the Science of Food and Agriculture",
title = "Lignin and organic free radicals in maize (Zea mays  L.) seeds in response to aflatoxin B1 contamination: an optical and EPR spectroscopic study",
volume = "102",
number = "6",
pages = "2500-2505",
doi = "10.1002/jsfa.11591"
}

Bartolić, D., Mojović, M., Prokopijević, M., Đikanović, D., Kalauzi, A., Mutavdžić, D., Baošić, R.,& Radotić, K.. (2022). Lignin and organic free radicals in maize (Zea mays  L.) seeds in response to aflatoxin B1 contamination: an optical and EPR spectroscopic study. in Journal of the Science of Food and Agriculture
Wiley., 102(6), 2500-2505.
https://doi.org/10.1002/jsfa.11591

Bartolić D, Mojović M, Prokopijević M, Đikanović D, Kalauzi A, Mutavdžić D, Baošić R, Radotić K. Lignin and organic free radicals in maize (Zea mays  L.) seeds in response to aflatoxin B1 contamination: an optical and EPR spectroscopic study. in Journal of the Science of Food and Agriculture. 2022;102(6):2500-2505.
doi:10.1002/jsfa.11591 .

Bartolić, Dragana, Mojović, Miloš, Prokopijević, Miloš, Đikanović, Daniela, Kalauzi, Aleksandar, Mutavdžić, Dragosav, Baošić, Rada, Radotić, Ksenija, "Lignin and organic free radicals in maize (Zea mays  L.) seeds in response to aflatoxin B1 contamination: an optical and EPR spectroscopic study" in Journal of the Science of Food and Agriculture, 102, no. 6 (2022):2500-2505,
https://doi.org/10.1002/jsfa.11591 . .

TY  - JOUR
AU  - Milikić, Jadranka
AU  - Knežević, Sara
AU  - Stojadinović, Stevan
AU  - Alsaiari, Mabkhoot
AU  - Harraz, Farid A.
AU  - Santos, Diogo M. F.
AU  - Šljukić, Biljana
PY  - 2022
UR  - https://www.mdpi.com/2079-4991/12/15/2657
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5524
AB  - Copper-silver and cobalt-silver alloy nanoparticles deposited on reduced graphene oxide (CuAg/rGO and CoAg/rGO) were synthesized and examined as electrocatalysts for oxygen reduction reaction (ORR) and hydrogen peroxide reduction reaction (HPRR) in alkaline media. Characterization of the prepared samples was done by transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray diffraction analysis (XRD), and scanning electron microscopy with integrated energy-dispersive X-ray spectroscopy (SEM-EDS). CuAg/rGO and CoAg/rGO nanoparticles diameter ranged from 0.4 to 9.2 nm. The Ag loading was ca. 40 wt.% for both electrocatalysts, with that for Cu and Co being 35 and 17 wt.%, respectively. CoAg/rGO electrocatalyst showed a Tafel slope of 109 mV dec−1, significantly lower than that for CuAg/rGO (184 mV dec−1), suggesting faster ORR kinetics. Additionally, a higher diffusion current density was obtained for CoAg/rGO (−2.63 mA cm−2) than for CuAg/rGO (−1.74 mA cm−2). The average value of the number of electrons transferred during ORR was 2.8 for CuAg/rGO and 3.3 for CoAg/rGO electrocatalyst, further confirming the higher ORR activity of the latter. On the other hand, CuAg/rGO showed higher peak current densities (−3.96 mA cm−2) for HPRR compared to those recorded for CoAg/rGO electrocatalyst (−1.96 mA cm−2).
PB  - MDPI
T2  - Nanomaterials
T1  - Facile Synthesis of Low-Cost Copper-Silver and Cobalt-Silver Alloy Nanoparticles on Reduced Graphene Oxide as Efficient Electrocatalysts for Oxygen Reduction Reaction in Alkaline Media
VL  - 12
IS  - 15
SP  - 2657
DO  - 10.3390/nano12152657
ER  - 

@article{
author = "Milikić, Jadranka and Knežević, Sara and Stojadinović, Stevan and Alsaiari, Mabkhoot and Harraz, Farid A. and Santos, Diogo M. F. and Šljukić, Biljana",
year = "2022",
abstract = "Copper-silver and cobalt-silver alloy nanoparticles deposited on reduced graphene oxide (CuAg/rGO and CoAg/rGO) were synthesized and examined as electrocatalysts for oxygen reduction reaction (ORR) and hydrogen peroxide reduction reaction (HPRR) in alkaline media. Characterization of the prepared samples was done by transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray diffraction analysis (XRD), and scanning electron microscopy with integrated energy-dispersive X-ray spectroscopy (SEM-EDS). CuAg/rGO and CoAg/rGO nanoparticles diameter ranged from 0.4 to 9.2 nm. The Ag loading was ca. 40 wt.% for both electrocatalysts, with that for Cu and Co being 35 and 17 wt.%, respectively. CoAg/rGO electrocatalyst showed a Tafel slope of 109 mV dec−1, significantly lower than that for CuAg/rGO (184 mV dec−1), suggesting faster ORR kinetics. Additionally, a higher diffusion current density was obtained for CoAg/rGO (−2.63 mA cm−2) than for CuAg/rGO (−1.74 mA cm−2). The average value of the number of electrons transferred during ORR was 2.8 for CuAg/rGO and 3.3 for CoAg/rGO electrocatalyst, further confirming the higher ORR activity of the latter. On the other hand, CuAg/rGO showed higher peak current densities (−3.96 mA cm−2) for HPRR compared to those recorded for CoAg/rGO electrocatalyst (−1.96 mA cm−2).",
publisher = "MDPI",
journal = "Nanomaterials",
title = "Facile Synthesis of Low-Cost Copper-Silver and Cobalt-Silver Alloy Nanoparticles on Reduced Graphene Oxide as Efficient Electrocatalysts for Oxygen Reduction Reaction in Alkaline Media",
volume = "12",
number = "15",
pages = "2657",
doi = "10.3390/nano12152657"
}

Milikić, J., Knežević, S., Stojadinović, S., Alsaiari, M., Harraz, F. A., Santos, D. M. F.,& Šljukić, B.. (2022). Facile Synthesis of Low-Cost Copper-Silver and Cobalt-Silver Alloy Nanoparticles on Reduced Graphene Oxide as Efficient Electrocatalysts for Oxygen Reduction Reaction in Alkaline Media. in Nanomaterials
MDPI., 12(15), 2657.
https://doi.org/10.3390/nano12152657

Milikić J, Knežević S, Stojadinović S, Alsaiari M, Harraz FA, Santos DMF, Šljukić B. Facile Synthesis of Low-Cost Copper-Silver and Cobalt-Silver Alloy Nanoparticles on Reduced Graphene Oxide as Efficient Electrocatalysts for Oxygen Reduction Reaction in Alkaline Media. in Nanomaterials. 2022;12(15):2657.
doi:10.3390/nano12152657 .

Milikić, Jadranka, Knežević, Sara, Stojadinović, Stevan, Alsaiari, Mabkhoot, Harraz, Farid A., Santos, Diogo M. F., Šljukić, Biljana, "Facile Synthesis of Low-Cost Copper-Silver and Cobalt-Silver Alloy Nanoparticles on Reduced Graphene Oxide as Efficient Electrocatalysts for Oxygen Reduction Reaction in Alkaline Media" in Nanomaterials, 12, no. 15 (2022):2657,
https://doi.org/10.3390/nano12152657 . .

TY  - CONF
AU  - Bubanja, Itana Nuša
AU  - Lončarević, Branka D.
AU  - Lješević, Marija
AU  - Stanisavljev, Dragomir
AU  - Beškoski, Vladimir
AU  - Gojgić-Cvijović, Gordana D.
AU  - Bajuk-Bogdanović, Danica
AU  - Gizdavić-Nikolaidis, Marija
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5430
AB  - Microwave assisted synthesis of polyaniline modified by pullulan (PANI/Pull) composite wasperformed by aniline oxidation with potassium iodate. The PANI/Pull composite was characterizedusing ATR-FTIR technique. FTIR spectra confirm presence of both components in PANI/Pullcomposite. Antimicrobial evaluation of PANI/Pull material performed by using a qualitative diskdiffusion method on Candida albicans (C. albicans) culture showed very high sensitivity toPANI/Pull composite. Observed FTIR and antifungal activity represent a promising results especiallyfor potential biomedical applications of PANI/Pull composite.
PB  - Society of Physical Chemists of Serbia
C3  - Proceedings - Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry
T1  - Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite
VL  - 2
SP  - 445
EP  - 448
UR  - https://hdl.handle.net/21.15107/rcub_cer_4955
ER  - 

@conference{
author = "Bubanja, Itana Nuša and Lončarević, Branka D. and Lješević, Marija and Stanisavljev, Dragomir and Beškoski, Vladimir and Gojgić-Cvijović, Gordana D. and Bajuk-Bogdanović, Danica and Gizdavić-Nikolaidis, Marija",
year = "2021",
abstract = "Microwave assisted synthesis of polyaniline modified by pullulan (PANI/Pull) composite wasperformed by aniline oxidation with potassium iodate. The PANI/Pull composite was characterizedusing ATR-FTIR technique. FTIR spectra confirm presence of both components in PANI/Pullcomposite. Antimicrobial evaluation of PANI/Pull material performed by using a qualitative diskdiffusion method on Candida albicans (C. albicans) culture showed very high sensitivity toPANI/Pull composite. Observed FTIR and antifungal activity represent a promising results especiallyfor potential biomedical applications of PANI/Pull composite.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Proceedings - Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite",
volume = "2",
pages = "445-448",
url = "https://hdl.handle.net/21.15107/rcub_cer_4955"
}

Bubanja, I. N., Lončarević, B. D., Lješević, M., Stanisavljev, D., Beškoski, V., Gojgić-Cvijović, G. D., Bajuk-Bogdanović, D.,& Gizdavić-Nikolaidis, M.. (2021). Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite. in Proceedings - Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry
Society of Physical Chemists of Serbia., 2, 445-448.
https://hdl.handle.net/21.15107/rcub_cer_4955

Bubanja IN, Lončarević BD, Lješević M, Stanisavljev D, Beškoski V, Gojgić-Cvijović GD, Bajuk-Bogdanović D, Gizdavić-Nikolaidis M. Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite. in Proceedings - Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry. 2021;2:445-448.
https://hdl.handle.net/21.15107/rcub_cer_4955 .

Bubanja, Itana Nuša, Lončarević, Branka D., Lješević, Marija, Stanisavljev, Dragomir, Beškoski, Vladimir, Gojgić-Cvijović, Gordana D., Bajuk-Bogdanović, Danica, Gizdavić-Nikolaidis, Marija, "Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite" in Proceedings - Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, 2 (2021):445-448,
https://hdl.handle.net/21.15107/rcub_cer_4955 .

TY  - CONF
AU  - Bubanja, Itana Nuša
AU  - Lončarević, Branka D.
AU  - Lješević, Marija
AU  - Stanisavljev, Dragomir
AU  - Beškoski, Vladimir
AU  - Gojgić-Cvijović, Gordana D.
AU  - Bajuk-Bogdanović, Danica
AU  - Gizdavić-Nikolaidis, Marija
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5431
AB  - Poster presented at Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry
T1  - Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite
UR  - https://hdl.handle.net/21.15107/rcub_cer_4956
ER  - 

@conference{
author = "Bubanja, Itana Nuša and Lončarević, Branka D. and Lješević, Marija and Stanisavljev, Dragomir and Beškoski, Vladimir and Gojgić-Cvijović, Gordana D. and Bajuk-Bogdanović, Danica and Gizdavić-Nikolaidis, Marija",
year = "2021",
abstract = "Poster presented at Physical Chemistry 2021, 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite",
url = "https://hdl.handle.net/21.15107/rcub_cer_4956"
}

Bubanja, I. N., Lončarević, B. D., Lješević, M., Stanisavljev, D., Beškoski, V., Gojgić-Cvijović, G. D., Bajuk-Bogdanović, D.,& Gizdavić-Nikolaidis, M.. (2021). Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite. .
https://hdl.handle.net/21.15107/rcub_cer_4956

Bubanja IN, Lončarević BD, Lješević M, Stanisavljev D, Beškoski V, Gojgić-Cvijović GD, Bajuk-Bogdanović D, Gizdavić-Nikolaidis M. Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite. 2021;.
https://hdl.handle.net/21.15107/rcub_cer_4956 .

Bubanja, Itana Nuša, Lončarević, Branka D., Lješević, Marija, Stanisavljev, Dragomir, Beškoski, Vladimir, Gojgić-Cvijović, Gordana D., Bajuk-Bogdanović, Danica, Gizdavić-Nikolaidis, Marija, "Microwave assisted synthesis of polyaniline/pullulan (pani/pull) composite" (2021),
https://hdl.handle.net/21.15107/rcub_cer_4956 .

TY  - JOUR
AU  - Krunić, Matija
AU  - Ristić, Biljana
AU  - Bošnjak, Mihajlo
AU  - Paunović, Verica
AU  - Tovilović-Kovačević, Gordana
AU  - Zagović, Nevena
AU  - Mirčić, Aleksandar
AU  - Marković, Zoran
AU  - Todorović Marković, Biljana
AU  - Jovanović, Svetlana
AU  - Kleut, Duška
AU  - Mojović, Miloš
AU  - Nakarada, Đura
AU  - Marković, Olivera S.
AU  - Vuković, Irena
AU  - Harhaji-Trajković, Ljubica
AU  - Trajković, Vladimir
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5467
AB  - We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuro blastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP). 
GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent 
apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers 
displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of 
GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (
•
OH), superoxide 
anion (O2
•− ), and lipid peroxidation. Nonselective antioxidants, •
OH scavenging, and iron chelators, but not 
superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •
OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal 
protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective 
effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagy limiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proauto phagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The 
antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and 
dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early 
(wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of 
GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •
OH/NO 
scavenging and induction of cytoprotective autophagy.
PB  - Elsevier
T2  - Free Radical Biology and Medicine
T1  - Graphene quantum dot antioxidant and proautophagic actions protect  SH-SY5Y neuroblastoma cells from oxidative stress-mediated  apoptotic death
VL  - 177
SP  - 167
EP  - 180
DO  - 10.1016/j.freeradbiomed.2021.10.025
ER  - 

@article{
author = "Krunić, Matija and Ristić, Biljana and Bošnjak, Mihajlo and Paunović, Verica and Tovilović-Kovačević, Gordana and Zagović, Nevena and Mirčić, Aleksandar and Marković, Zoran and Todorović Marković, Biljana and Jovanović, Svetlana and Kleut, Duška and Mojović, Miloš and Nakarada, Đura and Marković, Olivera S. and Vuković, Irena and Harhaji-Trajković, Ljubica and Trajković, Vladimir",
year = "2021",
abstract = "We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuro blastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP). 
GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent 
apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers 
displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of 
GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (
•
OH), superoxide 
anion (O2
•− ), and lipid peroxidation. Nonselective antioxidants, •
OH scavenging, and iron chelators, but not 
superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •
OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal 
protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective 
effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagy limiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proauto phagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The 
antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and 
dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early 
(wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of 
GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •
OH/NO 
scavenging and induction of cytoprotective autophagy.",
publisher = "Elsevier",
journal = "Free Radical Biology and Medicine",
title = "Graphene quantum dot antioxidant and proautophagic actions protect  SH-SY5Y neuroblastoma cells from oxidative stress-mediated  apoptotic death",
volume = "177",
pages = "167-180",
doi = "10.1016/j.freeradbiomed.2021.10.025"
}

Krunić, M., Ristić, B., Bošnjak, M., Paunović, V., Tovilović-Kovačević, G., Zagović, N., Mirčić, A., Marković, Z., Todorović Marković, B., Jovanović, S., Kleut, D., Mojović, M., Nakarada, Đ., Marković, O. S., Vuković, I., Harhaji-Trajković, L.,& Trajković, V.. (2021). Graphene quantum dot antioxidant and proautophagic actions protect  SH-SY5Y neuroblastoma cells from oxidative stress-mediated  apoptotic death. in Free Radical Biology and Medicine
Elsevier., 177, 167-180.
https://doi.org/10.1016/j.freeradbiomed.2021.10.025

Krunić M, Ristić B, Bošnjak M, Paunović V, Tovilović-Kovačević G, Zagović N, Mirčić A, Marković Z, Todorović Marković B, Jovanović S, Kleut D, Mojović M, Nakarada Đ, Marković OS, Vuković I, Harhaji-Trajković L, Trajković V. Graphene quantum dot antioxidant and proautophagic actions protect  SH-SY5Y neuroblastoma cells from oxidative stress-mediated  apoptotic death. in Free Radical Biology and Medicine. 2021;177:167-180.
doi:10.1016/j.freeradbiomed.2021.10.025 .

Krunić, Matija, Ristić, Biljana, Bošnjak, Mihajlo, Paunović, Verica, Tovilović-Kovačević, Gordana, Zagović, Nevena, Mirčić, Aleksandar, Marković, Zoran, Todorović Marković, Biljana, Jovanović, Svetlana, Kleut, Duška, Mojović, Miloš, Nakarada, Đura, Marković, Olivera S., Vuković, Irena, Harhaji-Trajković, Ljubica, Trajković, Vladimir, "Graphene quantum dot antioxidant and proautophagic actions protect  SH-SY5Y neuroblastoma cells from oxidative stress-mediated  apoptotic death" in Free Radical Biology and Medicine, 177 (2021):167-180,
https://doi.org/10.1016/j.freeradbiomed.2021.10.025 . .

TY  - JOUR
AU  - Lačnjevac, Uroš
AU  - Vasilić, Rastko
AU  - Dobrota, Ana S.
AU  - Đurđić, Slađana Z.
AU  - Tomanec, Ondřej
AU  - Zbořil, Radek
AU  - Mohajernia, Shiva
AU  - Nguyen, Nhat Truong
AU  - Skorodumova, Natalia
AU  - Manojlović, Dragan D.
AU  - Elezović, Nevenka
AU  - Pašti, Igor
AU  - Schmuki, Patrik
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4288
AB  - Developing ultraefficient electrocatalytic materials for the hydrogen evolution reaction (HER) with low content of expensive platinum group metals (PGMs) via low-energy-input procedures is the key to the successful commercialization of green water electrolysis technologies for sustainable production of high-purity hydrogen. In this study, we report a facile room-temperature synthesis of ultrafine metallic Ir nanoparticles on conductive, proton-intercalated TiO2 nanotube (H-TNT) arrays via galvanic displacement. A series of experiments demonstrate that a controlled transformation of the H-TNT surface microstructure from neat open-top tubes to disordered nanostripe bundles (“nanograss”) is highly beneficial for providing an abundance of exposed Ir active sites. Consequently, for nanograss-engineered composites, outstanding HER activity metrics are achieved even at very low Ir(III) precursor concentrations. An optimum Ir@TNT cathode loaded with 5.7 μgIr cm−2 exhibits an overpotential of −63 mV at −100 mA cm−2 and a mass activity of 34 A mgIr−1 at −80 mV under acidic conditions, along with excellent catalytic durability and structural integrity. Density functional theory (DFT) simulations reveal that the hydrogen-rich TiO2 surface not only stabilizes the deposited Ir and weakens its H binding strength to a moderate intensity, but also actively takes part in the HER mechanism by refreshing the Ir catalytic sites near the Ir|H–TiO2 interface, thus substantially promoting H2 generation. The comprehensive characterization combined with theory provides an in-depth understanding of the electrocatalytic behavior of H-TNT supported PGM nanoparticles and demonstrates their high potential as competitive electrocatalyst systems for the HER.
PB  - Royal Society of Chemistry
T2  - Journal of Materials Chemistry A
T1  - High-performance hydrogen evolution electrocatalysis using proton-intercalated TiO2 nanotube arrays as interactive supports for Ir nanoparticles
VL  - 8
IS  - 43
SP  - 22773
EP  - 22790
DO  - 10.1039/D0TA07492F
ER  - 

@article{
author = "Lačnjevac, Uroš and Vasilić, Rastko and Dobrota, Ana S. and Đurđić, Slađana Z. and Tomanec, Ondřej and Zbořil, Radek and Mohajernia, Shiva and Nguyen, Nhat Truong and Skorodumova, Natalia and Manojlović, Dragan D. and Elezović, Nevenka and Pašti, Igor and Schmuki, Patrik",
year = "2020",
abstract = "Developing ultraefficient electrocatalytic materials for the hydrogen evolution reaction (HER) with low content of expensive platinum group metals (PGMs) via low-energy-input procedures is the key to the successful commercialization of green water electrolysis technologies for sustainable production of high-purity hydrogen. In this study, we report a facile room-temperature synthesis of ultrafine metallic Ir nanoparticles on conductive, proton-intercalated TiO2 nanotube (H-TNT) arrays via galvanic displacement. A series of experiments demonstrate that a controlled transformation of the H-TNT surface microstructure from neat open-top tubes to disordered nanostripe bundles (“nanograss”) is highly beneficial for providing an abundance of exposed Ir active sites. Consequently, for nanograss-engineered composites, outstanding HER activity metrics are achieved even at very low Ir(III) precursor concentrations. An optimum Ir@TNT cathode loaded with 5.7 μgIr cm−2 exhibits an overpotential of −63 mV at −100 mA cm−2 and a mass activity of 34 A mgIr−1 at −80 mV under acidic conditions, along with excellent catalytic durability and structural integrity. Density functional theory (DFT) simulations reveal that the hydrogen-rich TiO2 surface not only stabilizes the deposited Ir and weakens its H binding strength to a moderate intensity, but also actively takes part in the HER mechanism by refreshing the Ir catalytic sites near the Ir|H–TiO2 interface, thus substantially promoting H2 generation. The comprehensive characterization combined with theory provides an in-depth understanding of the electrocatalytic behavior of H-TNT supported PGM nanoparticles and demonstrates their high potential as competitive electrocatalyst systems for the HER.",
publisher = "Royal Society of Chemistry",
journal = "Journal of Materials Chemistry A",
title = "High-performance hydrogen evolution electrocatalysis using proton-intercalated TiO2 nanotube arrays as interactive supports for Ir nanoparticles",
volume = "8",
number = "43",
pages = "22773-22790",
doi = "10.1039/D0TA07492F"
}

Lačnjevac, U., Vasilić, R., Dobrota, A. S., Đurđić, S. Z., Tomanec, O., Zbořil, R., Mohajernia, S., Nguyen, N. T., Skorodumova, N., Manojlović, D. D., Elezović, N., Pašti, I.,& Schmuki, P.. (2020). High-performance hydrogen evolution electrocatalysis using proton-intercalated TiO2 nanotube arrays as interactive supports for Ir nanoparticles. in Journal of Materials Chemistry A
Royal Society of Chemistry., 8(43), 22773-22790.
https://doi.org/10.1039/D0TA07492F

Lačnjevac U, Vasilić R, Dobrota AS, Đurđić SZ, Tomanec O, Zbořil R, Mohajernia S, Nguyen NT, Skorodumova N, Manojlović DD, Elezović N, Pašti I, Schmuki P. High-performance hydrogen evolution electrocatalysis using proton-intercalated TiO2 nanotube arrays as interactive supports for Ir nanoparticles. in Journal of Materials Chemistry A. 2020;8(43):22773-22790.
doi:10.1039/D0TA07492F .

Lačnjevac, Uroš, Vasilić, Rastko, Dobrota, Ana S., Đurđić, Slađana Z., Tomanec, Ondřej, Zbořil, Radek, Mohajernia, Shiva, Nguyen, Nhat Truong, Skorodumova, Natalia, Manojlović, Dragan D., Elezović, Nevenka, Pašti, Igor, Schmuki, Patrik, "High-performance hydrogen evolution electrocatalysis using proton-intercalated TiO2 nanotube arrays as interactive supports for Ir nanoparticles" in Journal of Materials Chemistry A, 8, no. 43 (2020):22773-22790,
https://doi.org/10.1039/D0TA07492F . .