TY  - DATA
AU  - Penjišević, Jelena 
AU  - Šukalović, Vladimir 
AU  - Dukić-Stefanović, Slađana
AU  - Deuther-Conrad, Winnie
AU  - Andrić, Deana 
AU  - Kostić-Rajačić, Slađana
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5845
AB  - Serotonin receptors modulate numerous behavioral and neuropsychological processes. Therefore, they are the target for the action of many drugs, such as antipsychotics, antidepressants, antiemetics, migraine remedies, and many others. The 5-HT1A receptors have been involved in the pathogenesis and treatment of anxiety and depression and represent a promising target for new drugs with reduced extrapyramidal side effects. In most antidepressants, a piperazine-based structural motif can be identified as a common moiety. Here we describe the synthesis, pharmacological, and in silico characterization of a novel arylpiperazines series with excellent 5-HT1A affinity. The final compounds, 4a, 8a, and 8b, were selected according to predictions of in silico pharmacokinetics, docking analysis, and molecular dynamics in conjunction with physical properties, and metabolic stability. The accentuated molecules could serve as a lead compound for developing 5-HT1A drug-like molecules for depression treatment.
PB  - Elsevier
T2  - Arabian Journal of Chemistry
T1  - Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636
VL  - 16
IS  - 4
SP  - 104636
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5845
ER  - 

@misc{
author = "Penjišević, Jelena  and Šukalović, Vladimir  and Dukić-Stefanović, Slađana and Deuther-Conrad, Winnie and Andrić, Deana  and Kostić-Rajačić, Slađana",
abstract = "Serotonin receptors modulate numerous behavioral and neuropsychological processes. Therefore, they are the target for the action of many drugs, such as antipsychotics, antidepressants, antiemetics, migraine remedies, and many others. The 5-HT1A receptors have been involved in the pathogenesis and treatment of anxiety and depression and represent a promising target for new drugs with reduced extrapyramidal side effects. In most antidepressants, a piperazine-based structural motif can be identified as a common moiety. Here we describe the synthesis, pharmacological, and in silico characterization of a novel arylpiperazines series with excellent 5-HT1A affinity. The final compounds, 4a, 8a, and 8b, were selected according to predictions of in silico pharmacokinetics, docking analysis, and molecular dynamics in conjunction with physical properties, and metabolic stability. The accentuated molecules could serve as a lead compound for developing 5-HT1A drug-like molecules for depression treatment.",
publisher = "Elsevier",
journal = "Arabian Journal of Chemistry",
title = "Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636",
volume = "16",
number = "4",
pages = "104636",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5845"
}

Penjišević, J., Šukalović, V., Dukić-Stefanović, S., Deuther-Conrad, W., Andrić, D.,& Kostić-Rajačić, S..Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636. in Arabian Journal of Chemistry
Elsevier., 16(4), 104636.
https://hdl.handle.net/21.15107/rcub_cherry_5845

Penjišević J, Šukalović V, Dukić-Stefanović S, Deuther-Conrad W, Andrić D, Kostić-Rajačić S. Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636. in Arabian Journal of Chemistry.16(4):104636.
https://hdl.handle.net/21.15107/rcub_cherry_5845 .

Penjišević, Jelena , Šukalović, Vladimir , Dukić-Stefanović, Slađana, Deuther-Conrad, Winnie, Andrić, Deana , Kostić-Rajačić, Slađana, "Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636" in Arabian Journal of Chemistry, 16, no. 4:104636,
https://hdl.handle.net/21.15107/rcub_cherry_5845 .

TY  - DATA
AU  - Aleksić, Jovana
AU  - Stojanović, Milovan
AU  - Bošković, Jakša
AU  - Baranac-Stojanović, Marija
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5846
AB  - We present the green, highly atom-economical, solid-state silica gel-catalyzed synthesis of polysubstituted 1,4- and 1,2-dihydropyridines (DHPs) from commercially available materials, amines and ethyl propiolate. The DHP skeleton was assembled by heating the reactants and silica gel in a closed vessel. Aliphatic amines provided 1,4-isomers as the main or only DHP products, but the reactions of aromatic amines yielded a mixture of 1,4- and 1,2-isomers. To the best of our knowledge, this is the first example of the formation of a 1,2-DHP structure by the reaction of an amine with propiolic ester. Addition of 1 mass percent of H2SO4 to silica gel shifted the product distribution to 1,4-DHP as the main or the only isomer obtained. Experimental and theoretical analyses led to the identification of two key intermediates en route to DHPs and the explanation of the observed regioisomeric ratios. 1,2-DHPs show blue-cyan fluorescence in MeOH with the quantum yield Φ = 0.10–0.22 relative to quinine sulfate Φ = 0.58 and 1,4-DHPs show blue-violet fluorescence with Φ = 0.09–0.81.
PB  - Royal Society of Chemistry
T2  - Organic & Biomolecular Chemistry
T1  - Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F
VL  - 21
IS  - 6
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5846
ER  - 

@misc{
author = "Aleksić, Jovana and Stojanović, Milovan and Bošković, Jakša and Baranac-Stojanović, Marija",
abstract = "We present the green, highly atom-economical, solid-state silica gel-catalyzed synthesis of polysubstituted 1,4- and 1,2-dihydropyridines (DHPs) from commercially available materials, amines and ethyl propiolate. The DHP skeleton was assembled by heating the reactants and silica gel in a closed vessel. Aliphatic amines provided 1,4-isomers as the main or only DHP products, but the reactions of aromatic amines yielded a mixture of 1,4- and 1,2-isomers. To the best of our knowledge, this is the first example of the formation of a 1,2-DHP structure by the reaction of an amine with propiolic ester. Addition of 1 mass percent of H2SO4 to silica gel shifted the product distribution to 1,4-DHP as the main or the only isomer obtained. Experimental and theoretical analyses led to the identification of two key intermediates en route to DHPs and the explanation of the observed regioisomeric ratios. 1,2-DHPs show blue-cyan fluorescence in MeOH with the quantum yield Φ = 0.10–0.22 relative to quinine sulfate Φ = 0.58 and 1,4-DHPs show blue-violet fluorescence with Φ = 0.09–0.81.",
publisher = "Royal Society of Chemistry",
journal = "Organic & Biomolecular Chemistry",
title = "Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F",
volume = "21",
number = "6",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5846"
}

Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M..Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6).
https://hdl.handle.net/21.15107/rcub_cherry_5846

Aleksić J, Stojanović M, Bošković J, Baranac-Stojanović M. Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F. in Organic & Biomolecular Chemistry.21(6).
https://hdl.handle.net/21.15107/rcub_cherry_5846 .

Aleksić, Jovana, Stojanović, Milovan, Bošković, Jakša, Baranac-Stojanović, Marija, "Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F" in Organic & Biomolecular Chemistry, 21, no. 6,
https://hdl.handle.net/21.15107/rcub_cherry_5846 .

TY  - JOUR
AU  - Kokanović, Andrija
AU  - Ajdačić, Vladimir
AU  - Terzić-Jovanović, Natasa
AU  - Stankić, Slavica
AU  - Opsenica, Igor
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6282
AB  - Herein, we report the synthesis and application of a highly active and
versatile Pd/chemical vapor synthesis-ZnO (Pd/CVS-ZnO) catalytic system. The twostep
preparation of the catalyst includes chemical vapor synthesis (CVS) of ultrapure
ZnO nanotetrapods, followed by the liquid-phase in situ reduction of a Pd precursor
and deposition of polycrystalline Pd nanoparticles (∼6 nm). The as-synthesized catalyst
was characterized using standard instrumental techniques. The catalyst was successfully
applied in four chemical reactions: Suzuki−Miyaura cross-coupling, reduction of
nitroarenes, decarbonylation, and hydrodebromination of aromatic compounds, of
which, the latter two are reported for the first time for the Pd/ZnO catalytic system.
The catalyst showed excellent activity within a wide range of substrates, delivering the products in high yields (70−99%). The
recyclability of the Pd/CVS-ZnO catalyst was tested through two different approaches. First, the catalyst recyclability was examined
in all four reactions, reusing the catalyst up to four times in the Suzuki−Miyaura cross-coupling reaction, as well as the reduction of
4-nitrobenzonitrile, without a significant loss of yield. Furthermore, the catalyst was successively used in three different reactions,
showing a high degree of stability and delivering excellent product yields in all cases. In addition to its excellent activity, versatility,
and stability, the Pd/CVS-ZnO catalytic system also exhibits excellent recyclability over consecutive runs, which makes it a
promising candidate for future application in complex industrial processes.
PB  - American Chemical Society
T2  - ACS Applied Nano Materials
T1  - Pd Nanoparticles Supported on Ultrapure ZnO Nanopowders as Reusable Multipurpose Catalysts
VL  - 6
IS  - 17
SP  - 15820
EP  - 15828
DO  - 10.1021/acsanm.3c02743
ER  - 

@article{
author = "Kokanović, Andrija and Ajdačić, Vladimir and Terzić-Jovanović, Natasa and Stankić, Slavica and Opsenica, Igor",
year = "2023",
abstract = "Herein, we report the synthesis and application of a highly active and
versatile Pd/chemical vapor synthesis-ZnO (Pd/CVS-ZnO) catalytic system. The twostep
preparation of the catalyst includes chemical vapor synthesis (CVS) of ultrapure
ZnO nanotetrapods, followed by the liquid-phase in situ reduction of a Pd precursor
and deposition of polycrystalline Pd nanoparticles (∼6 nm). The as-synthesized catalyst
was characterized using standard instrumental techniques. The catalyst was successfully
applied in four chemical reactions: Suzuki−Miyaura cross-coupling, reduction of
nitroarenes, decarbonylation, and hydrodebromination of aromatic compounds, of
which, the latter two are reported for the first time for the Pd/ZnO catalytic system.
The catalyst showed excellent activity within a wide range of substrates, delivering the products in high yields (70−99%). The
recyclability of the Pd/CVS-ZnO catalyst was tested through two different approaches. First, the catalyst recyclability was examined
in all four reactions, reusing the catalyst up to four times in the Suzuki−Miyaura cross-coupling reaction, as well as the reduction of
4-nitrobenzonitrile, without a significant loss of yield. Furthermore, the catalyst was successively used in three different reactions,
showing a high degree of stability and delivering excellent product yields in all cases. In addition to its excellent activity, versatility,
and stability, the Pd/CVS-ZnO catalytic system also exhibits excellent recyclability over consecutive runs, which makes it a
promising candidate for future application in complex industrial processes.",
publisher = "American Chemical Society",
journal = "ACS Applied Nano Materials",
title = "Pd Nanoparticles Supported on Ultrapure ZnO Nanopowders as Reusable Multipurpose Catalysts",
volume = "6",
number = "17",
pages = "15820-15828",
doi = "10.1021/acsanm.3c02743"
}

Kokanović, A., Ajdačić, V., Terzić-Jovanović, N., Stankić, S.,& Opsenica, I.. (2023). Pd Nanoparticles Supported on Ultrapure ZnO Nanopowders as Reusable Multipurpose Catalysts. in ACS Applied Nano Materials
American Chemical Society., 6(17), 15820-15828.
https://doi.org/10.1021/acsanm.3c02743

Kokanović A, Ajdačić V, Terzić-Jovanović N, Stankić S, Opsenica I. Pd Nanoparticles Supported on Ultrapure ZnO Nanopowders as Reusable Multipurpose Catalysts. in ACS Applied Nano Materials. 2023;6(17):15820-15828.
doi:10.1021/acsanm.3c02743 .

Kokanović, Andrija, Ajdačić, Vladimir, Terzić-Jovanović, Natasa, Stankić, Slavica, Opsenica, Igor, "Pd Nanoparticles Supported on Ultrapure ZnO Nanopowders as Reusable Multipurpose Catalysts" in ACS Applied Nano Materials, 6, no. 17 (2023):15820-15828,
https://doi.org/10.1021/acsanm.3c02743 . .

TY  - JOUR
AU  - Marković, Srdjan
AU  - Andrejević, Natalija S.
AU  - Milošević, Jelica
AU  - Polović, Natalija Đ
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6289
AB  - The significant role of papain-like cysteine proteases, including papain, cathepsin L and SARS-CoV-2 PLpro, in biomedicine and biotechnology makes them interesting model systems for sensor development. These enzymes have a free thiol group that is suitable for many sensor designs including strong binding to gold nanoparticles or low-molecular-weight inhibitors. Focusing on the importance of the preservation of native protein structure for inhibitor-binding and molecular-imprinting, which has been applied in some efficient examples of sensor development, the aim of this work was to examine the effects of the free-thiol-group’s reversible blocking on papain denaturation that is the basis of its activity loss and aggregation. To utilize biophysical methods common in protein structural transitions characterization, such as fluorimetry and high-resolution infrared spectroscopy, low-molecular-weight electrophilic thiol blocking reagent S-Methyl methanethiosulfonate (MMTS) was used in solution. MMTS binding led to a two-fold increase in 8-Anilinonaphthalene-1-sulfonic acid fluorescence, indicating increased hydrophobic residue exposure. A more in-depth analysis showed significant transitions on the secondary structure level upon MMTS binding, mostly characterized by the lowered content of α-helices and unordered structures (either for approximately one third), and the increase in aggregation-specific β-sheets (from 25 to 52%) in a dose-dependant manner. The recovery of this inhibited protein showed that reversibility of inhibition is accompanied by reversibility of protein denaturation. Nevertheless, a 100-fold molar excess of the inhibitor led to the incomplete recovery of proteolytic activity, which can be explained by irreversible denaturation. The structural stability of the C-terminal β-sheet rich domain of the papain-like cysteine protease family opens up an interesting possibility to use its foldamers as a strategy for sensor development and other multiple potential applications that rely on the great commercial value of papain-like cysteine proteases.
PB  - MDPI
T2  - Biomimetics
T1  - Structural Transitions of Papain-like Cysteine Proteases: Implications for Sensor Development
VL  - 8
IS  - 3
SP  - 281
DO  - 10.3390/biomimetics8030281
ER  - 

@article{
author = "Marković, Srdjan and Andrejević, Natalija S. and Milošević, Jelica and Polović, Natalija Đ",
year = "2023",
abstract = "The significant role of papain-like cysteine proteases, including papain, cathepsin L and SARS-CoV-2 PLpro, in biomedicine and biotechnology makes them interesting model systems for sensor development. These enzymes have a free thiol group that is suitable for many sensor designs including strong binding to gold nanoparticles or low-molecular-weight inhibitors. Focusing on the importance of the preservation of native protein structure for inhibitor-binding and molecular-imprinting, which has been applied in some efficient examples of sensor development, the aim of this work was to examine the effects of the free-thiol-group’s reversible blocking on papain denaturation that is the basis of its activity loss and aggregation. To utilize biophysical methods common in protein structural transitions characterization, such as fluorimetry and high-resolution infrared spectroscopy, low-molecular-weight electrophilic thiol blocking reagent S-Methyl methanethiosulfonate (MMTS) was used in solution. MMTS binding led to a two-fold increase in 8-Anilinonaphthalene-1-sulfonic acid fluorescence, indicating increased hydrophobic residue exposure. A more in-depth analysis showed significant transitions on the secondary structure level upon MMTS binding, mostly characterized by the lowered content of α-helices and unordered structures (either for approximately one third), and the increase in aggregation-specific β-sheets (from 25 to 52%) in a dose-dependant manner. The recovery of this inhibited protein showed that reversibility of inhibition is accompanied by reversibility of protein denaturation. Nevertheless, a 100-fold molar excess of the inhibitor led to the incomplete recovery of proteolytic activity, which can be explained by irreversible denaturation. The structural stability of the C-terminal β-sheet rich domain of the papain-like cysteine protease family opens up an interesting possibility to use its foldamers as a strategy for sensor development and other multiple potential applications that rely on the great commercial value of papain-like cysteine proteases.",
publisher = "MDPI",
journal = "Biomimetics",
title = "Structural Transitions of Papain-like Cysteine Proteases: Implications for Sensor Development",
volume = "8",
number = "3",
pages = "281",
doi = "10.3390/biomimetics8030281"
}

Marković, S., Andrejević, N. S., Milošević, J.,& Polović, N. Đ.. (2023). Structural Transitions of Papain-like Cysteine Proteases: Implications for Sensor Development. in Biomimetics
MDPI., 8(3), 281.
https://doi.org/10.3390/biomimetics8030281

Marković S, Andrejević NS, Milošević J, Polović NĐ. Structural Transitions of Papain-like Cysteine Proteases: Implications for Sensor Development. in Biomimetics. 2023;8(3):281.
doi:10.3390/biomimetics8030281 .

Marković, Srdjan, Andrejević, Natalija S., Milošević, Jelica, Polović, Natalija Đ, "Structural Transitions of Papain-like Cysteine Proteases: Implications for Sensor Development" in Biomimetics, 8, no. 3 (2023):281,
https://doi.org/10.3390/biomimetics8030281 . .

TY  - JOUR
AU  - Zdravkov, Alexander
AU  - Groß, Doris
AU  - Bechtel, Achim
AU  - Stojanović, Ksenija
AU  - Kojić, Ivan
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6288
AB  - The paper reports results from organic petrological and geochemical characterization of Suhostrel bituminous coal deposit, SW Bulgaria. Three high ash (21–47 wt%) and thin (up to 0.6 m) coal seams, representing splits from a locally compact coal bed (∼1.8 m thick), were formed around the southern and south-western rim of the Padesh Graben during its Eocene evolution. High total organic carbon contents (avg. ∼86 wt%, daf), vitrinite reflectance (avg. Ro = 1.05%) and Tmax (avg. 457 °C) argue for high vol. A/medium vol. bituminous coalification rank. Maceral composition is dominated by vitrinite (avg. ∼ 95 vol%), accompanied by small amounts of liptinite (avg. ∼ 5 vol%). Apart from few occurrences of funginite, inertinite is not present. The organic matter is mostly represented by detrovitrinite and collotelinite, the latter generally occurring in the form of gelified leaf-derived tissues. Liptinite is mainly represented by cutinite and microsporinite and display no evidence for organic matter contribution from algae. Low TPI and VI indices indicate peat formation from vegetation with poor preservation potential. Insignificant contents of gelovitrinite, coupled with high GI indices denote greater importance of the geochemical processes for the gelification of the organic matter. Striking predominance of mid- and long-chain n-alkanes argues for peat formation from a mixture of aquatic macrophytes and terrestrial vegetational communities. Presence of oleanane, albeit in low concentration, provides robust argument for contribution from angiosperm plants, whereas absence of resin-derived sesqui- and diterpenoid hydrocarbons denotes insignificant role of conifers during peat accumulation. Reconstructed depositional settings indicate organic matter accumulation under marginal aquatic, marsh/fen-type peatland with meso- to rheotrophic characteristics (GWI > 0.5). High mineral matter contents, coupled with the abundance of siliciclastic grains, imply hydrologically active environment. Plant remains deposited under oxidizing conditions (Pr/Ph = 1.5–2.5), but because of high water table were likely subjected to frequent (perhaps seasonal) changes in Eh settings. The resultant limited aerobic biodegradation of the plant remains is evidenced by low concentrations of hopanoid biomarkers and their diagenetic degradation products – drimane-type sesquiterpenoids. Post-depositional marine influence and downward infiltrating sulfate-rich waters is considered responsible for the presence of dibenzothiophene derivatives in Suhostrel coal. All molecular maturity-related ratios (e.g. CPI, Ts/(Ts + Tm), βα/(αβ + βα) C30 hopanes, ββ/(ββ + αα) C29 steranes, MPI-1, etc.) are fully compatible with the bulk geochemical parameters (e.g., TOC, Tmax, Ro) and confirm the bituminous coalification rank of the coal. Based on this data, temperatures of ∼130–140 °C were likely reached during burial of the sediments in a zone, characterized by high thermal influx (geothermal gradient ∼43–47 °C/km).
PB  - Elsevier
T2  - International Journal of Coal Geology
T1  - Depositional settings of the Eocene Suhostrel bituminous coal, SW Bulgaria, inferred from organic petrology and molecular proxies
VL  - 276
SP  - 104319
DO  - 10.1016/j.coal.2023.104319
ER  - 

@article{
author = "Zdravkov, Alexander and Groß, Doris and Bechtel, Achim and Stojanović, Ksenija and Kojić, Ivan",
year = "2023",
abstract = "The paper reports results from organic petrological and geochemical characterization of Suhostrel bituminous coal deposit, SW Bulgaria. Three high ash (21–47 wt%) and thin (up to 0.6 m) coal seams, representing splits from a locally compact coal bed (∼1.8 m thick), were formed around the southern and south-western rim of the Padesh Graben during its Eocene evolution. High total organic carbon contents (avg. ∼86 wt%, daf), vitrinite reflectance (avg. Ro = 1.05%) and Tmax (avg. 457 °C) argue for high vol. A/medium vol. bituminous coalification rank. Maceral composition is dominated by vitrinite (avg. ∼ 95 vol%), accompanied by small amounts of liptinite (avg. ∼ 5 vol%). Apart from few occurrences of funginite, inertinite is not present. The organic matter is mostly represented by detrovitrinite and collotelinite, the latter generally occurring in the form of gelified leaf-derived tissues. Liptinite is mainly represented by cutinite and microsporinite and display no evidence for organic matter contribution from algae. Low TPI and VI indices indicate peat formation from vegetation with poor preservation potential. Insignificant contents of gelovitrinite, coupled with high GI indices denote greater importance of the geochemical processes for the gelification of the organic matter. Striking predominance of mid- and long-chain n-alkanes argues for peat formation from a mixture of aquatic macrophytes and terrestrial vegetational communities. Presence of oleanane, albeit in low concentration, provides robust argument for contribution from angiosperm plants, whereas absence of resin-derived sesqui- and diterpenoid hydrocarbons denotes insignificant role of conifers during peat accumulation. Reconstructed depositional settings indicate organic matter accumulation under marginal aquatic, marsh/fen-type peatland with meso- to rheotrophic characteristics (GWI > 0.5). High mineral matter contents, coupled with the abundance of siliciclastic grains, imply hydrologically active environment. Plant remains deposited under oxidizing conditions (Pr/Ph = 1.5–2.5), but because of high water table were likely subjected to frequent (perhaps seasonal) changes in Eh settings. The resultant limited aerobic biodegradation of the plant remains is evidenced by low concentrations of hopanoid biomarkers and their diagenetic degradation products – drimane-type sesquiterpenoids. Post-depositional marine influence and downward infiltrating sulfate-rich waters is considered responsible for the presence of dibenzothiophene derivatives in Suhostrel coal. All molecular maturity-related ratios (e.g. CPI, Ts/(Ts + Tm), βα/(αβ + βα) C30 hopanes, ββ/(ββ + αα) C29 steranes, MPI-1, etc.) are fully compatible with the bulk geochemical parameters (e.g., TOC, Tmax, Ro) and confirm the bituminous coalification rank of the coal. Based on this data, temperatures of ∼130–140 °C were likely reached during burial of the sediments in a zone, characterized by high thermal influx (geothermal gradient ∼43–47 °C/km).",
publisher = "Elsevier",
journal = "International Journal of Coal Geology",
title = "Depositional settings of the Eocene Suhostrel bituminous coal, SW Bulgaria, inferred from organic petrology and molecular proxies",
volume = "276",
pages = "104319",
doi = "10.1016/j.coal.2023.104319"
}

Zdravkov, A., Groß, D., Bechtel, A., Stojanović, K.,& Kojić, I.. (2023). Depositional settings of the Eocene Suhostrel bituminous coal, SW Bulgaria, inferred from organic petrology and molecular proxies. in International Journal of Coal Geology
Elsevier., 276, 104319.
https://doi.org/10.1016/j.coal.2023.104319

Zdravkov A, Groß D, Bechtel A, Stojanović K, Kojić I. Depositional settings of the Eocene Suhostrel bituminous coal, SW Bulgaria, inferred from organic petrology and molecular proxies. in International Journal of Coal Geology. 2023;276:104319.
doi:10.1016/j.coal.2023.104319 .

Zdravkov, Alexander, Groß, Doris, Bechtel, Achim, Stojanović, Ksenija, Kojić, Ivan, "Depositional settings of the Eocene Suhostrel bituminous coal, SW Bulgaria, inferred from organic petrology and molecular proxies" in International Journal of Coal Geology, 276 (2023):104319,
https://doi.org/10.1016/j.coal.2023.104319 . .

TY  - JOUR
AU  - Topakas, Evangelos
AU  - Siaperas, Romanos
AU  - Taxeidis, George
AU  - Makryniotis, Konstantinos
AU  - Guzik, Maciej
AU  - Maslak, Veselin
AU  - Beškoski, Vladimir
AU  - Lončarević, Branka
AU  - Ilić-Tomić, Tatjana
AU  - Milivojević, Dušan
AU  - Škaro Bogojević, Sanja
AU  - Pantelić, Brana
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5969
AB  - Polyurethanes (PUs) are an exceedingly heterogeneous group of plastic polymers, widely used in a variety of industries from construction to medical implants. In the past decades, we have witnessed the accumulation of PU waste and its detrimental environmental impacts. PUs have been identified as one of the most toxic polymers leaching hazardous compounds derived both from the polymer itself and the additives used in production. Further environmental impact assessment, identification and characterization of substances derived from PU materials and establishing efficient degradation strategies are crucial. Thus, a selection of eight synthetic model compounds which represent partial PU hydrolysis products were synthesized and characterized both in terms of toxicity and suitability to be used as substrates for the identification of novel biocatalysts for PU biodegradation. Overall, the compounds exhibited low in vitro cytotoxicity against a healthy human fibroblast cell line and virtually no toxic effect on the nematode Caenorhabditis elegans up to 500 µg mL−1, and two of the substrates showed moderate aquatic ecotoxicity with EC50 values 53 µg mL−1 and 45 µg mL−1, respectively, on Aliivibrio fischeri. The compounds were successfully applied to study the mechanism of ester and urethane bond cleaving preference of known plastic-degrading enzymes and were used to single out a novel PU-degrading biocatalyst, Amycolatopsis mediterranei ISP5501, among 220 microbial strains. A. mediterranei ISP5501 can also degrade commercially available polyether and polyester PU materials, reducing the average molecular number of the polymer up to 13.5%. This study uncovered a biocatalyst capable of degrading different types of PUs and identified potential enzymes responsible as a key step in developing biotechnological process for PU waste treatment options.
PB  - MDPI
T2  - Catalysts
T1  - Set of Small Molecule Polyurethane (PU) Model Substrates: Ecotoxicity Evaluation and Identification of PU Degrading Biocatalysts
VL  - 13
IS  - 2
SP  - 278
DO  - 10.3390/catal13020278
ER  - 

@article{
author = "Topakas, Evangelos and Siaperas, Romanos and Taxeidis, George and Makryniotis, Konstantinos and Guzik, Maciej and Maslak, Veselin and Beškoski, Vladimir and Lončarević, Branka and Ilić-Tomić, Tatjana and Milivojević, Dušan and Škaro Bogojević, Sanja and Pantelić, Brana",
year = "2023",
abstract = "Polyurethanes (PUs) are an exceedingly heterogeneous group of plastic polymers, widely used in a variety of industries from construction to medical implants. In the past decades, we have witnessed the accumulation of PU waste and its detrimental environmental impacts. PUs have been identified as one of the most toxic polymers leaching hazardous compounds derived both from the polymer itself and the additives used in production. Further environmental impact assessment, identification and characterization of substances derived from PU materials and establishing efficient degradation strategies are crucial. Thus, a selection of eight synthetic model compounds which represent partial PU hydrolysis products were synthesized and characterized both in terms of toxicity and suitability to be used as substrates for the identification of novel biocatalysts for PU biodegradation. Overall, the compounds exhibited low in vitro cytotoxicity against a healthy human fibroblast cell line and virtually no toxic effect on the nematode Caenorhabditis elegans up to 500 µg mL−1, and two of the substrates showed moderate aquatic ecotoxicity with EC50 values 53 µg mL−1 and 45 µg mL−1, respectively, on Aliivibrio fischeri. The compounds were successfully applied to study the mechanism of ester and urethane bond cleaving preference of known plastic-degrading enzymes and were used to single out a novel PU-degrading biocatalyst, Amycolatopsis mediterranei ISP5501, among 220 microbial strains. A. mediterranei ISP5501 can also degrade commercially available polyether and polyester PU materials, reducing the average molecular number of the polymer up to 13.5%. This study uncovered a biocatalyst capable of degrading different types of PUs and identified potential enzymes responsible as a key step in developing biotechnological process for PU waste treatment options.",
publisher = "MDPI",
journal = "Catalysts",
title = "Set of Small Molecule Polyurethane (PU) Model Substrates: Ecotoxicity Evaluation and Identification of PU Degrading Biocatalysts",
volume = "13",
number = "2",
pages = "278",
doi = "10.3390/catal13020278"
}

Topakas, E., Siaperas, R., Taxeidis, G., Makryniotis, K., Guzik, M., Maslak, V., Beškoski, V., Lončarević, B., Ilić-Tomić, T., Milivojević, D., Škaro Bogojević, S.,& Pantelić, B.. (2023). Set of Small Molecule Polyurethane (PU) Model Substrates: Ecotoxicity Evaluation and Identification of PU Degrading Biocatalysts. in Catalysts
MDPI., 13(2), 278.
https://doi.org/10.3390/catal13020278

Topakas E, Siaperas R, Taxeidis G, Makryniotis K, Guzik M, Maslak V, Beškoski V, Lončarević B, Ilić-Tomić T, Milivojević D, Škaro Bogojević S, Pantelić B. Set of Small Molecule Polyurethane (PU) Model Substrates: Ecotoxicity Evaluation and Identification of PU Degrading Biocatalysts. in Catalysts. 2023;13(2):278.
doi:10.3390/catal13020278 .

Topakas, Evangelos, Siaperas, Romanos, Taxeidis, George, Makryniotis, Konstantinos, Guzik, Maciej, Maslak, Veselin, Beškoski, Vladimir, Lončarević, Branka, Ilić-Tomić, Tatjana, Milivojević, Dušan, Škaro Bogojević, Sanja, Pantelić, Brana, "Set of Small Molecule Polyurethane (PU) Model Substrates: Ecotoxicity Evaluation and Identification of PU Degrading Biocatalysts" in Catalysts, 13, no. 2 (2023):278,
https://doi.org/10.3390/catal13020278 . .

TY  - JOUR
AU  - Jakšić, Jovana
AU  - Solymosi, Iris
AU  - Hirsch, Andreas
AU  - Pérez-Ojeda, M. Eugenia
AU  - Mitrović, Aleksandra D.
AU  - Maslak, Veselin
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6272
AB  - The synthesis and characterization of four dumbbell-shaped fullerene molecules connected by isosorbide and isomannide moieties is presented. Additionally, their electrochemical behavior and their ability to form complexes with [10]cycloparaphenylene ([10]CPP) were investigated. The cyclic voltammetry (CV) results of the fullerene dumbbells demonstrate a high electron affinity, indicating their strong interaction with electron-donating counterparts such as carbon nanorings, which possess complementary charge and shape properties. To study the thermodynamic and kinetic parameters of complexation, isothermal titration calorimetry (ITC) was employed. NMR titration experiments provided further insights into the binding stoichiometries. Two distinct approaches were utilized to create bridged structures: one based on cyclopropane and the other based on furan. Regardless of the type of linker used, all derivatives formed conventional 2 : 1 complexes denoted as [10]CPP2 ⊃C60derivative . However, the methano-dumbbell molecules exhibited distinct binding behavior, resulting in the formation of mono- and bis-pseudorotaxanes, as well as oligomers (polymers). The formation of linear polymers holds significant potential for applications in solar energy conversion processes.
PB  - John Wiley and Sons Inc
T2  - Chemistry (Weinheim an Der Bergstrasse, Germany)
T1  - Sugar-Bridged Fullerene Dumbbells and Their Interaction with the [10]Cycloparaphenylene Nanoring
VL  - 29
IS  - 44
SP  - e202301061
DO  - 10.1002/chem.202301061
ER  - 

@article{
author = "Jakšić, Jovana and Solymosi, Iris and Hirsch, Andreas and Pérez-Ojeda, M. Eugenia and Mitrović, Aleksandra D. and Maslak, Veselin",
year = "2023",
abstract = "The synthesis and characterization of four dumbbell-shaped fullerene molecules connected by isosorbide and isomannide moieties is presented. Additionally, their electrochemical behavior and their ability to form complexes with [10]cycloparaphenylene ([10]CPP) were investigated. The cyclic voltammetry (CV) results of the fullerene dumbbells demonstrate a high electron affinity, indicating their strong interaction with electron-donating counterparts such as carbon nanorings, which possess complementary charge and shape properties. To study the thermodynamic and kinetic parameters of complexation, isothermal titration calorimetry (ITC) was employed. NMR titration experiments provided further insights into the binding stoichiometries. Two distinct approaches were utilized to create bridged structures: one based on cyclopropane and the other based on furan. Regardless of the type of linker used, all derivatives formed conventional 2 : 1 complexes denoted as [10]CPP2 ⊃C60derivative . However, the methano-dumbbell molecules exhibited distinct binding behavior, resulting in the formation of mono- and bis-pseudorotaxanes, as well as oligomers (polymers). The formation of linear polymers holds significant potential for applications in solar energy conversion processes.",
publisher = "John Wiley and Sons Inc",
journal = "Chemistry (Weinheim an Der Bergstrasse, Germany)",
title = "Sugar-Bridged Fullerene Dumbbells and Their Interaction with the [10]Cycloparaphenylene Nanoring",
volume = "29",
number = "44",
pages = "e202301061",
doi = "10.1002/chem.202301061"
}

Jakšić, J., Solymosi, I., Hirsch, A., Pérez-Ojeda, M. E., Mitrović, A. D.,& Maslak, V.. (2023). Sugar-Bridged Fullerene Dumbbells and Their Interaction with the [10]Cycloparaphenylene Nanoring. in Chemistry (Weinheim an Der Bergstrasse, Germany)
John Wiley and Sons Inc., 29(44), e202301061.
https://doi.org/10.1002/chem.202301061

Jakšić J, Solymosi I, Hirsch A, Pérez-Ojeda ME, Mitrović AD, Maslak V. Sugar-Bridged Fullerene Dumbbells and Their Interaction with the [10]Cycloparaphenylene Nanoring. in Chemistry (Weinheim an Der Bergstrasse, Germany). 2023;29(44):e202301061.
doi:10.1002/chem.202301061 .

Jakšić, Jovana, Solymosi, Iris, Hirsch, Andreas, Pérez-Ojeda, M. Eugenia, Mitrović, Aleksandra D., Maslak, Veselin, "Sugar-Bridged Fullerene Dumbbells and Their Interaction with the [10]Cycloparaphenylene Nanoring" in Chemistry (Weinheim an Der Bergstrasse, Germany), 29, no. 44 (2023):e202301061,
https://doi.org/10.1002/chem.202301061 . .

TY  - JOUR
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6284
AB  - Enallenylamides have been utilized for the synthesis of heterobicycle[4.2.0]octane derivatives via Ir/hν promoted [2+2] cycloaddition reaction. The reaction specifically targets the distal double bond of the allene moiety, and results in the exclusive formation of the trans product. The process is conducted at room temperature and under an inert atmosphere. An extensive study on the substituent propensities during the cycloaddition step revealed variable effects. Electron-withdrawing groups conjugated with the double bond participating in the cycloaddition either hindered the process or reduced its yield. Conversely, electron-donating substituents enhanced the efficiency, resulting in product yields ranging from 60% to 88%. Our study also demonstrated the influence of protecting groups on the reaction pathway.
AB  - Enallenylamideshave been utilizedforthe synthesisof heterobicycle[4.2.0]octanederiva-tives via Ir/hν promoted[2+2] cycloadditionreaction.The reactionspecificallytargets the distaldoublebond of the allene moiety, and resultsin theexclusiveformationof thetransproduct.Theprocessis conductedat room temperatureand underan inert atmosphere.An extensivestudy on thesubstituentpropensitiesduringthe cycloadditionstep revealedvariableeffects.Electron-withdrawinggroupsconjugatedwith the doublebond participat-ing in the cycloadditioneither hinderedthe processor reducedits yield. Conversely, electron-donatingsubstituentsenhancedthe efficiency, resultinginproductyields rangingfrom 60% to 88%. Our studyalso demonstratedthe influenceof protectinggroupson the reactionpathway.
PB  - John Wiley and Sons Inc
T2  - Advanced Synthesis and Catalysis
T1  - Regio‐ and Stereoselective, Intramolecular [2+2] Cycloaddition of Allenes, Promoted by Visible Light Photocatalysis
VL  - 365
IS  - 15
SP  - 2516
EP  - 2523
DO  - 10.1002/adsc.202300301
ER  - 

@article{
year = "2023",
abstract = "Enallenylamides have been utilized for the synthesis of heterobicycle[4.2.0]octane derivatives via Ir/hν promoted [2+2] cycloaddition reaction. The reaction specifically targets the distal double bond of the allene moiety, and results in the exclusive formation of the trans product. The process is conducted at room temperature and under an inert atmosphere. An extensive study on the substituent propensities during the cycloaddition step revealed variable effects. Electron-withdrawing groups conjugated with the double bond participating in the cycloaddition either hindered the process or reduced its yield. Conversely, electron-donating substituents enhanced the efficiency, resulting in product yields ranging from 60% to 88%. Our study also demonstrated the influence of protecting groups on the reaction pathway., Enallenylamideshave been utilizedforthe synthesisof heterobicycle[4.2.0]octanederiva-tives via Ir/hν promoted[2+2] cycloadditionreaction.The reactionspecificallytargets the distaldoublebond of the allene moiety, and resultsin theexclusiveformationof thetransproduct.Theprocessis conductedat room temperatureand underan inert atmosphere.An extensivestudy on thesubstituentpropensitiesduringthe cycloadditionstep revealedvariableeffects.Electron-withdrawinggroupsconjugatedwith the doublebond participat-ing in the cycloadditioneither hinderedthe processor reducedits yield. Conversely, electron-donatingsubstituentsenhancedthe efficiency, resultinginproductyields rangingfrom 60% to 88%. Our studyalso demonstratedthe influenceof protectinggroupson the reactionpathway.",
publisher = "John Wiley and Sons Inc",
journal = "Advanced Synthesis and Catalysis",
title = "Regio‐ and Stereoselective, Intramolecular [2+2] Cycloaddition of Allenes, Promoted by Visible Light Photocatalysis",
volume = "365",
number = "15",
pages = "2516-2523",
doi = "10.1002/adsc.202300301"
}

(2023). Regio‐ and Stereoselective, Intramolecular [2+2] Cycloaddition of Allenes, Promoted by Visible Light Photocatalysis. in Advanced Synthesis and Catalysis
John Wiley and Sons Inc., 365(15), 2516-2523.
https://doi.org/10.1002/adsc.202300301

Regio‐ and Stereoselective, Intramolecular [2+2] Cycloaddition of Allenes, Promoted by Visible Light Photocatalysis. in Advanced Synthesis and Catalysis. 2023;365(15):2516-2523.
doi:10.1002/adsc.202300301 .

"Regio‐ and Stereoselective, Intramolecular [2+2] Cycloaddition of Allenes, Promoted by Visible Light Photocatalysis" in Advanced Synthesis and Catalysis, 365, no. 15 (2023):2516-2523,
https://doi.org/10.1002/adsc.202300301 . .

TY  - JOUR
AU  - Mitrović, Aleksandra
AU  - Milovanović, Jelena
AU  - Gurgul, Jacek
AU  - Žekić, Andrijana
AU  - Nikodinović-Runić, Jasmina
AU  - Maslak, Veselin
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6287
AB  - We present a novel approach for the enzymatic functionalization of graphene, utilizing horseradish peroxidase (HPO) and laccase (LC) from Trametes versicolor. This study demonstrates, for the first time, the covalent modification of non-homogeneous graphene with a low surface-to-volume ratio, both in solution and on solid support. Through thermogravimetry analysis, we estimate the degree of functionalization to be 11% with HPO and 4% with LC, attributed to the varying redox potentials of the enzymes. This work highlights the potential of enzymatic reactions for tailored functionalization of graphene under mild conditions.
PB  - Elsevier
T2  - Enzyme and Microbial Technology
T1  - Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase
VL  - 170
SP  - 110293
DO  - 10.1016/j.enzmictec.2023.110293
ER  - 

@article{
author = "Mitrović, Aleksandra and Milovanović, Jelena and Gurgul, Jacek and Žekić, Andrijana and Nikodinović-Runić, Jasmina and Maslak, Veselin",
year = "2023",
abstract = "We present a novel approach for the enzymatic functionalization of graphene, utilizing horseradish peroxidase (HPO) and laccase (LC) from Trametes versicolor. This study demonstrates, for the first time, the covalent modification of non-homogeneous graphene with a low surface-to-volume ratio, both in solution and on solid support. Through thermogravimetry analysis, we estimate the degree of functionalization to be 11% with HPO and 4% with LC, attributed to the varying redox potentials of the enzymes. This work highlights the potential of enzymatic reactions for tailored functionalization of graphene under mild conditions.",
publisher = "Elsevier",
journal = "Enzyme and Microbial Technology",
title = "Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase",
volume = "170",
pages = "110293",
doi = "10.1016/j.enzmictec.2023.110293"
}

Mitrović, A., Milovanović, J., Gurgul, J., Žekić, A., Nikodinović-Runić, J.,& Maslak, V.. (2023). Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase. in Enzyme and Microbial Technology
Elsevier., 170, 110293.
https://doi.org/10.1016/j.enzmictec.2023.110293

Mitrović A, Milovanović J, Gurgul J, Žekić A, Nikodinović-Runić J, Maslak V. Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase. in Enzyme and Microbial Technology. 2023;170:110293.
doi:10.1016/j.enzmictec.2023.110293 .

Mitrović, Aleksandra, Milovanović, Jelena, Gurgul, Jacek, Žekić, Andrijana, Nikodinović-Runić, Jasmina, Maslak, Veselin, "Enzymatic functionalization of liquid phase exfoliated graphene using horseradish peroxidase and laccase" in Enzyme and Microbial Technology, 170 (2023):110293,
https://doi.org/10.1016/j.enzmictec.2023.110293 . .

TY  - JOUR
AU  - Pejčić, Tomislav
AU  - Zeković, Milica
AU  - Bumbaširević, Uroš
AU  - Kalaba, Milica
AU  - Vovk, Irena
AU  - Bensa, Maja
AU  - Popović, Lazar
AU  - Tešić, Živoslav Lj.
PY  - 2023
UR  - https://www.mdpi.com/2076-3921/12/2/368
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6181
AB  - This narrative review summarizes epidemiological studies on breast cancer and prostate cancer with an overview of their global incidence distribution to investigate the relationship between these diseases and diet. The biological properties, mechanisms of action, and available data supporting the potential role of isoflavones in the prevention of breast cancer and prostate cancer are discussed. Studies evaluating the effects of isoflavones in tissue cultures of normal and malignant breast and prostate cells, as well as the current body of research regarding the effects of isoflavones attained through multiple modifications of cellular molecular signaling pathways and control of oxidative stress, are summarized. Furthermore, this review compiles literature sources reporting on the following: (1) levels of estrogen in breast and prostate tissue; (2) levels of isoflavones in the normal and malignant tissue of these organs in European and Asian populations; (3) average concentrations of isoflavones in the secretion of these organs (milk and semen). Finally, particular emphasis is placed on studies investigating the effect of isoflavones on tissues via estrogen receptors (ER).
PB  - MDPI
T2  - Antioxidants
T1  - The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer
VL  - 12
IS  - 2
SP  - 368
DO  - 10.3390/antiox12020368
ER  - 

@article{
author = "Pejčić, Tomislav and Zeković, Milica and Bumbaširević, Uroš and Kalaba, Milica and Vovk, Irena and Bensa, Maja and Popović, Lazar and Tešić, Živoslav Lj.",
year = "2023",
abstract = "This narrative review summarizes epidemiological studies on breast cancer and prostate cancer with an overview of their global incidence distribution to investigate the relationship between these diseases and diet. The biological properties, mechanisms of action, and available data supporting the potential role of isoflavones in the prevention of breast cancer and prostate cancer are discussed. Studies evaluating the effects of isoflavones in tissue cultures of normal and malignant breast and prostate cells, as well as the current body of research regarding the effects of isoflavones attained through multiple modifications of cellular molecular signaling pathways and control of oxidative stress, are summarized. Furthermore, this review compiles literature sources reporting on the following: (1) levels of estrogen in breast and prostate tissue; (2) levels of isoflavones in the normal and malignant tissue of these organs in European and Asian populations; (3) average concentrations of isoflavones in the secretion of these organs (milk and semen). Finally, particular emphasis is placed on studies investigating the effect of isoflavones on tissues via estrogen receptors (ER).",
publisher = "MDPI",
journal = "Antioxidants",
title = "The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer",
volume = "12",
number = "2",
pages = "368",
doi = "10.3390/antiox12020368"
}

Pejčić, T., Zeković, M., Bumbaširević, U., Kalaba, M., Vovk, I., Bensa, M., Popović, L.,& Tešić, Ž. Lj.. (2023). The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer. in Antioxidants
MDPI., 12(2), 368.
https://doi.org/10.3390/antiox12020368

Pejčić T, Zeković M, Bumbaširević U, Kalaba M, Vovk I, Bensa M, Popović L, Tešić ŽL. The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer. in Antioxidants. 2023;12(2):368.
doi:10.3390/antiox12020368 .

Pejčić, Tomislav, Zeković, Milica, Bumbaširević, Uroš, Kalaba, Milica, Vovk, Irena, Bensa, Maja, Popović, Lazar, Tešić, Živoslav Lj., "The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer" in Antioxidants, 12, no. 2 (2023):368,
https://doi.org/10.3390/antiox12020368 . .

TY  - JOUR
AU  - Kostić, Aleksandar Ž
AU  - Milinčić, Danijel D.
AU  - Špirović Trifunović, Bojana
AU  - Nedić, Nebojša
AU  - Gašić, Uroš M.
AU  - Tešić, Živoslav Lj.
AU  - Stanojević, Sladjana P.
AU  - Pešić, Mirjana B.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6286
AB  - The aim of this study was to compile a detailed phytochemical profile and assess the antioxidant properties of bee-collected pollen (PBP) obtained from corn poppy (Papaver rhoeas L.) plants. To achieve this, a lipid fraction was prepared for quantifying fatty acids using GC-FID. Extractable and alkaline-hydrolysable PBP fractions (obtained from a defatted sample) were used to determine the qualitative and quantitative profiles of phenolic compounds, phenylamides and alkaloids using UHPLC/Q-ToF-MS. Additionally, various spectrophotometric assays (TAC, FRP, CUPRAC, DPPH⦁) were conducted to evaluate the antioxidant properties. Phenolic compounds were more present in the extractable fraction than in the alkaline-hydrolysable fraction. Luteolin was the predominant compound in the extractable fraction, followed by tricetin and various derivatives of kaempferol. This study presents one of the first reports on the quantification of tricetin aglycone outside the Myrtaceae plant family. The alkaline-hydrolysable fraction exhibited a different phenolic profile, with a significantly lower amount of phenolics. Kaempferol/derivatives, specific compounds like ferulic and 5-carboxyvanillic acids, and (epi)catechin 3-O-gallate were the predominant compounds in this fraction. Regarding phenylamides, the extractable fraction demonstrated a diverse range of these bioactive compounds, with a notable abundance of different spermine derivatives. In contrast, the hydrolysable fraction contained six spermine derivatives and one spermidine derivative. The examined fractions also revealed the presence of seventeen different alkaloids, belonging to the benzylisoquinoline, berberine and isoquinoline classes. The fatty-acid profile confirmed the prevalence of unsaturated fatty acids. Furthermore, both fractions exhibited significant antioxidant activity, with the extractable fraction showing particularly high activity. Among the assays conducted, the CUPRAC assay highlighted the exceptional ability of PBP’s bioactive compounds to reduce cupric ions.
T2  - Antioxidants
T2  - Antioxidants
T1  - Monofloral Corn Poppy Bee-Collected Pollen—A Detailed Insight into Its Phytochemical Composition and Antioxidant Properties
VL  - 12
IS  - 7
SP  - 1424
DO  - 10.3390/antiox12071424
ER  - 

@article{
author = "Kostić, Aleksandar Ž and Milinčić, Danijel D. and Špirović Trifunović, Bojana and Nedić, Nebojša and Gašić, Uroš M. and Tešić, Živoslav Lj. and Stanojević, Sladjana P. and Pešić, Mirjana B.",
year = "2023",
abstract = "The aim of this study was to compile a detailed phytochemical profile and assess the antioxidant properties of bee-collected pollen (PBP) obtained from corn poppy (Papaver rhoeas L.) plants. To achieve this, a lipid fraction was prepared for quantifying fatty acids using GC-FID. Extractable and alkaline-hydrolysable PBP fractions (obtained from a defatted sample) were used to determine the qualitative and quantitative profiles of phenolic compounds, phenylamides and alkaloids using UHPLC/Q-ToF-MS. Additionally, various spectrophotometric assays (TAC, FRP, CUPRAC, DPPH⦁) were conducted to evaluate the antioxidant properties. Phenolic compounds were more present in the extractable fraction than in the alkaline-hydrolysable fraction. Luteolin was the predominant compound in the extractable fraction, followed by tricetin and various derivatives of kaempferol. This study presents one of the first reports on the quantification of tricetin aglycone outside the Myrtaceae plant family. The alkaline-hydrolysable fraction exhibited a different phenolic profile, with a significantly lower amount of phenolics. Kaempferol/derivatives, specific compounds like ferulic and 5-carboxyvanillic acids, and (epi)catechin 3-O-gallate were the predominant compounds in this fraction. Regarding phenylamides, the extractable fraction demonstrated a diverse range of these bioactive compounds, with a notable abundance of different spermine derivatives. In contrast, the hydrolysable fraction contained six spermine derivatives and one spermidine derivative. The examined fractions also revealed the presence of seventeen different alkaloids, belonging to the benzylisoquinoline, berberine and isoquinoline classes. The fatty-acid profile confirmed the prevalence of unsaturated fatty acids. Furthermore, both fractions exhibited significant antioxidant activity, with the extractable fraction showing particularly high activity. Among the assays conducted, the CUPRAC assay highlighted the exceptional ability of PBP’s bioactive compounds to reduce cupric ions.",
journal = "Antioxidants, Antioxidants",
title = "Monofloral Corn Poppy Bee-Collected Pollen—A Detailed Insight into Its Phytochemical Composition and Antioxidant Properties",
volume = "12",
number = "7",
pages = "1424",
doi = "10.3390/antiox12071424"
}

Kostić, A. Ž., Milinčić, D. D., Špirović Trifunović, B., Nedić, N., Gašić, U. M., Tešić, Ž. Lj., Stanojević, S. P.,& Pešić, M. B.. (2023). Monofloral Corn Poppy Bee-Collected Pollen—A Detailed Insight into Its Phytochemical Composition and Antioxidant Properties. in Antioxidants, 12(7), 1424.
https://doi.org/10.3390/antiox12071424

Kostić AŽ, Milinčić DD, Špirović Trifunović B, Nedić N, Gašić UM, Tešić ŽL, Stanojević SP, Pešić MB. Monofloral Corn Poppy Bee-Collected Pollen—A Detailed Insight into Its Phytochemical Composition and Antioxidant Properties. in Antioxidants. 2023;12(7):1424.
doi:10.3390/antiox12071424 .

Kostić, Aleksandar Ž, Milinčić, Danijel D., Špirović Trifunović, Bojana, Nedić, Nebojša, Gašić, Uroš M., Tešić, Živoslav Lj., Stanojević, Sladjana P., Pešić, Mirjana B., "Monofloral Corn Poppy Bee-Collected Pollen—A Detailed Insight into Its Phytochemical Composition and Antioxidant Properties" in Antioxidants, 12, no. 7 (2023):1424,
https://doi.org/10.3390/antiox12071424 . .

TY  - JOUR
AU  - Krstić, Đurđa D.
AU  - Ristivojević, Petar
AU  - Gašić, Uroš M.
AU  - Lazović, Mila
AU  - Fotirić-Akšić, Milica M.
AU  - Milivojević, Jasminka
AU  - Morlock, Gertrud E.
AU  - Milojković-Opsenica, Dušanka
AU  - Trifković, Jelena
PY  - 2023
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/5633
AB  - Considering the health-benefits of berry fruits consumption and increased market demands for food authenticity
as one of the most important quality assurances, phenolic profiling by high-performance thin layer chroma-
tography and ultra-high-performance liquid chromatography hyphenated with mass spectrometry was combined
with multivariate analysis for phytochemical characterization and intercultivar discrimination of cultivated
berry seeds. The phenolic profiles of 45 berry seeds from nine genuine Serbian cultivated fruit species (straw-
berry, raspberry, blackberry, black currant, blueberry, gooseberry, cape gooseberry, chokeberry, and goji berry)
revealed a good differentiation according to botanical origin. In order to determine biomarkers responsible for
the classification, a total of 103 phenolic compounds were identified, including 53 phenolic acids and their
derivatives, 26 flavonoids and 24 glycosides. Biomarkers derived from the phenolic profile of berry seeds proved
to be a powerful tool in the authentication of botanical origin, and may be useful in detection of frauds in berry-
based seed-containing product.
PB  - Elsevier
T2  - Food Chemistry
T1  - Authenticity assessment of cultivated berries via phenolic profiles of seeds
VL  - 402
SP  - 134184
DO  - 10.1016/j.foodchem.2022.134184
ER  - 

@article{
author = "Krstić, Đurđa D. and Ristivojević, Petar and Gašić, Uroš M. and Lazović, Mila and Fotirić-Akšić, Milica M. and Milivojević, Jasminka and Morlock, Gertrud E. and Milojković-Opsenica, Dušanka and Trifković, Jelena",
year = "2023",
abstract = "Considering the health-benefits of berry fruits consumption and increased market demands for food authenticity
as one of the most important quality assurances, phenolic profiling by high-performance thin layer chroma-
tography and ultra-high-performance liquid chromatography hyphenated with mass spectrometry was combined
with multivariate analysis for phytochemical characterization and intercultivar discrimination of cultivated
berry seeds. The phenolic profiles of 45 berry seeds from nine genuine Serbian cultivated fruit species (straw-
berry, raspberry, blackberry, black currant, blueberry, gooseberry, cape gooseberry, chokeberry, and goji berry)
revealed a good differentiation according to botanical origin. In order to determine biomarkers responsible for
the classification, a total of 103 phenolic compounds were identified, including 53 phenolic acids and their
derivatives, 26 flavonoids and 24 glycosides. Biomarkers derived from the phenolic profile of berry seeds proved
to be a powerful tool in the authentication of botanical origin, and may be useful in detection of frauds in berry-
based seed-containing product.",
publisher = "Elsevier",
journal = "Food Chemistry",
title = "Authenticity assessment of cultivated berries via phenolic profiles of seeds",
volume = "402",
pages = "134184",
doi = "10.1016/j.foodchem.2022.134184"
}

Krstić, Đ. D., Ristivojević, P., Gašić, U. M., Lazović, M., Fotirić-Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D.,& Trifković, J.. (2023). Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry
Elsevier., 402, 134184.
https://doi.org/10.1016/j.foodchem.2022.134184

Krstić ĐD, Ristivojević P, Gašić UM, Lazović M, Fotirić-Akšić MM, Milivojević J, Morlock GE, Milojković-Opsenica D, Trifković J. Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry. 2023;402:134184.
doi:10.1016/j.foodchem.2022.134184 .

Krstić, Đurđa D., Ristivojević, Petar, Gašić, Uroš M., Lazović, Mila, Fotirić-Akšić, Milica M., Milivojević, Jasminka, Morlock, Gertrud E., Milojković-Opsenica, Dušanka, Trifković, Jelena, "Authenticity assessment of cultivated berries via phenolic profiles of seeds" in Food Chemistry, 402 (2023):134184,
https://doi.org/10.1016/j.foodchem.2022.134184 . .

TY  - DATA
AU  - Krstić, Đurđa D.
AU  - Ristivojević, Petar
AU  - Gašić, Uroš M.
AU  - Lazović, Mila
AU  - Fotirić-Akšić, Milica M.
AU  - Milivojević, Jasminka
AU  - Morlock, Gertrud E.
AU  - Milojković-Opsenica, Dušanka
AU  - Trifković, Jelena
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5633
AB  - Considering the health-benefits of berry fruits consumption and increased market demands for food authenticityas one of the most important quality assurances, phenolic profiling by high-performance thin layer chroma-tography and ultra-high-performance liquid chromatography hyphenated with mass spectrometry was combinedwith multivariate analysis for phytochemical characterization and intercultivar discrimination of cultivatedberry seeds. The phenolic profiles of 45 berry seeds from nine genuine Serbian cultivated fruit species (straw-berry, raspberry, blackberry, black currant, blueberry, gooseberry, cape gooseberry, chokeberry, and goji berry)revealed a good differentiation according to botanical origin. In order to determine biomarkers responsible forthe classification, a total of 103 phenolic compounds were identified, including 53 phenolic acids and theirderivatives, 26 flavonoids and 24 glycosides. Biomarkers derived from the phenolic profile of berry seeds provedto be a powerful tool in the authentication of botanical origin, and may be useful in detection of frauds in berry-based seed-containing product.
PB  - Elsevier
T2  - Food Chemistry
T1  - Supplementary material for: Krstić, Đ. D., Ristivojević, P. M., Gašić, U. M., Lazović, M., Fotirić Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D. M.,& Trifković, J. Đ.. (2023). Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry Elsevier., 402, 134184. https://doi.org/10.1016/j.foodchem.2022.134184
VL  - 402
SP  - 134184
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5633
ER  - 

@misc{
author = "Krstić, Đurđa D. and Ristivojević, Petar and Gašić, Uroš M. and Lazović, Mila and Fotirić-Akšić, Milica M. and Milivojević, Jasminka and Morlock, Gertrud E. and Milojković-Opsenica, Dušanka and Trifković, Jelena",
year = "2023",
abstract = "Considering the health-benefits of berry fruits consumption and increased market demands for food authenticityas one of the most important quality assurances, phenolic profiling by high-performance thin layer chroma-tography and ultra-high-performance liquid chromatography hyphenated with mass spectrometry was combinedwith multivariate analysis for phytochemical characterization and intercultivar discrimination of cultivatedberry seeds. The phenolic profiles of 45 berry seeds from nine genuine Serbian cultivated fruit species (straw-berry, raspberry, blackberry, black currant, blueberry, gooseberry, cape gooseberry, chokeberry, and goji berry)revealed a good differentiation according to botanical origin. In order to determine biomarkers responsible forthe classification, a total of 103 phenolic compounds were identified, including 53 phenolic acids and theirderivatives, 26 flavonoids and 24 glycosides. Biomarkers derived from the phenolic profile of berry seeds provedto be a powerful tool in the authentication of botanical origin, and may be useful in detection of frauds in berry-based seed-containing product.",
publisher = "Elsevier",
journal = "Food Chemistry",
title = "Supplementary material for: Krstić, Đ. D., Ristivojević, P. M., Gašić, U. M., Lazović, M., Fotirić Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D. M.,& Trifković, J. Đ.. (2023). Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry Elsevier., 402, 134184. https://doi.org/10.1016/j.foodchem.2022.134184",
volume = "402",
pages = "134184",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5633"
}

Krstić, Đ. D., Ristivojević, P., Gašić, U. M., Lazović, M., Fotirić-Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D.,& Trifković, J.. (2023). Supplementary material for: Krstić, Đ. D., Ristivojević, P. M., Gašić, U. M., Lazović, M., Fotirić Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D. M.,& Trifković, J. Đ.. (2023). Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry Elsevier., 402, 134184. https://doi.org/10.1016/j.foodchem.2022.134184. in Food Chemistry
Elsevier., 402, 134184.
https://hdl.handle.net/21.15107/rcub_cherry_5633

Krstić ĐD, Ristivojević P, Gašić UM, Lazović M, Fotirić-Akšić MM, Milivojević J, Morlock GE, Milojković-Opsenica D, Trifković J. Supplementary material for: Krstić, Đ. D., Ristivojević, P. M., Gašić, U. M., Lazović, M., Fotirić Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D. M.,& Trifković, J. Đ.. (2023). Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry Elsevier., 402, 134184. https://doi.org/10.1016/j.foodchem.2022.134184. in Food Chemistry. 2023;402:134184.
https://hdl.handle.net/21.15107/rcub_cherry_5633 .

Krstić, Đurđa D., Ristivojević, Petar, Gašić, Uroš M., Lazović, Mila, Fotirić-Akšić, Milica M., Milivojević, Jasminka, Morlock, Gertrud E., Milojković-Opsenica, Dušanka, Trifković, Jelena, "Supplementary material for: Krstić, Đ. D., Ristivojević, P. M., Gašić, U. M., Lazović, M., Fotirić Akšić, M. M., Milivojević, J., Morlock, G. E., Milojković-Opsenica, D. M.,& Trifković, J. Đ.. (2023). Authenticity assessment of cultivated berries via phenolic profiles of seeds. in Food Chemistry Elsevier., 402, 134184. https://doi.org/10.1016/j.foodchem.2022.134184" in Food Chemistry, 402 (2023):134184,
https://hdl.handle.net/21.15107/rcub_cherry_5633 .

TY  - JOUR
AU  - Jurič, Andreja
AU  - Brčić Karačonji, Irena
AU  - Gašić, Uroš M.
AU  - Milojković-Opsenica, Dušanka
AU  - Prđun, Saša
AU  - Bubalo, Dragan
AU  - Lušić, Dražen
AU  - Vahčić, Nada
AU  - Kopjar, Nevenka
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5874
AB  - Strawberry tree (Arbutus unedo L.) honey (STH) has been used since ancient times as a folk medicine remedy, especially in certain Mediterranean countries. This honey, rich in phenolic content, is well recognized for its antioxidant, anti-inflammatory, and antimicrobial activities, and is used for the treatment of skin lesions as well as gastrointestinal and respiratory disorders. This study investigated whether STH alleviates genome damage in human peripheral blood lymphocytes produced by the cytotoxic drug irinotecan. The phenolic profile of STH was previously estimated by ultra-high-performance liquid chromatography coupled to a linear ion trap–Orbitrap hybrid mass spectrometer. The effects of STH were evaluated at three concentrations (1×, 5×, and 10×), based on the daily consumption of the honey by an adult person. After 2 h of in vitro exposure, standard lymphocyte cultures for the analysis of chromosome aberrations and the cytokinesis-block micronucleus cytome assay were established. Our results demonstrate that STH offered remarkable geno- and cytoprotection when administered with irinotecan. These findings are relevant for drawing preliminary conclusions regarding the in vitro safety of the tested honey. However, further studies are needed with the application of more complex experimental models.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study
VL  - 24
IS  - 3
SP  - 1903
DO  - 10.3390/ijms24031903
ER  - 

@article{
author = "Jurič, Andreja and Brčić Karačonji, Irena and Gašić, Uroš M. and Milojković-Opsenica, Dušanka and Prđun, Saša and Bubalo, Dragan and Lušić, Dražen and Vahčić, Nada and Kopjar, Nevenka",
year = "2023",
abstract = "Strawberry tree (Arbutus unedo L.) honey (STH) has been used since ancient times as a folk medicine remedy, especially in certain Mediterranean countries. This honey, rich in phenolic content, is well recognized for its antioxidant, anti-inflammatory, and antimicrobial activities, and is used for the treatment of skin lesions as well as gastrointestinal and respiratory disorders. This study investigated whether STH alleviates genome damage in human peripheral blood lymphocytes produced by the cytotoxic drug irinotecan. The phenolic profile of STH was previously estimated by ultra-high-performance liquid chromatography coupled to a linear ion trap–Orbitrap hybrid mass spectrometer. The effects of STH were evaluated at three concentrations (1×, 5×, and 10×), based on the daily consumption of the honey by an adult person. After 2 h of in vitro exposure, standard lymphocyte cultures for the analysis of chromosome aberrations and the cytokinesis-block micronucleus cytome assay were established. Our results demonstrate that STH offered remarkable geno- and cytoprotection when administered with irinotecan. These findings are relevant for drawing preliminary conclusions regarding the in vitro safety of the tested honey. However, further studies are needed with the application of more complex experimental models.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study",
volume = "24",
number = "3",
pages = "1903",
doi = "10.3390/ijms24031903"
}

Jurič, A., Brčić Karačonji, I., Gašić, U. M., Milojković-Opsenica, D., Prđun, S., Bubalo, D., Lušić, D., Vahčić, N.,& Kopjar, N.. (2023). Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study. in International Journal of Molecular Sciences
MDPI., 24(3), 1903.
https://doi.org/10.3390/ijms24031903

Jurič A, Brčić Karačonji I, Gašić UM, Milojković-Opsenica D, Prđun S, Bubalo D, Lušić D, Vahčić N, Kopjar N. Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study. in International Journal of Molecular Sciences. 2023;24(3):1903.
doi:10.3390/ijms24031903 .

Jurič, Andreja, Brčić Karačonji, Irena, Gašić, Uroš M., Milojković-Opsenica, Dušanka, Prđun, Saša, Bubalo, Dragan, Lušić, Dražen, Vahčić, Nada, Kopjar, Nevenka, "Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study" in International Journal of Molecular Sciences, 24, no. 3 (2023):1903,
https://doi.org/10.3390/ijms24031903 . .

TY  - DATA
AU  - Jurič, Andreja
AU  - Brčić Karačonji, Irena
AU  - Gašić, Uroš M.
AU  - Milojković-Opsenica, Dušanka
AU  - Prđun, Saša
AU  - Bubalo, Dragan
AU  - Lušić, Dražen
AU  - Vahčić, Nada
AU  - Kopjar, Nevenka
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5875
AB  - Strawberry tree (Arbutus unedo L.) honey (STH) has been used since ancient times as a folk medicine remedy, especially in certain Mediterranean countries. This honey, rich in phenolic content, is well recognized for its antioxidant, anti-inflammatory, and antimicrobial activities, and is used for the treatment of skin lesions as well as gastrointestinal and respiratory disorders. This study investigated whether STH alleviates genome damage in human peripheral blood lymphocytes produced by the cytotoxic drug irinotecan. The phenolic profile of STH was previously estimated by ultra-high-performance liquid chromatography coupled to a linear ion trap–Orbitrap hybrid mass spectrometer. The effects of STH were evaluated at three concentrations (1×, 5×, and 10×), based on the daily consumption of the honey by an adult person. After 2 h of in vitro exposure, standard lymphocyte cultures for the analysis of chromosome aberrations and the cytokinesis-block micronucleus cytome assay were established. Our results demonstrate that STH offered remarkable geno- and cytoprotection when administered with irinotecan. These findings are relevant for drawing preliminary conclusions regarding the in vitro safety of the tested honey. However, further studies are needed with the application of more complex experimental models.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Supplementary material for: Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study
VL  - 24
IS  - 3
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5875
ER  - 

@misc{
author = "Jurič, Andreja and Brčić Karačonji, Irena and Gašić, Uroš M. and Milojković-Opsenica, Dušanka and Prđun, Saša and Bubalo, Dragan and Lušić, Dražen and Vahčić, Nada and Kopjar, Nevenka",
year = "2023",
abstract = "Strawberry tree (Arbutus unedo L.) honey (STH) has been used since ancient times as a folk medicine remedy, especially in certain Mediterranean countries. This honey, rich in phenolic content, is well recognized for its antioxidant, anti-inflammatory, and antimicrobial activities, and is used for the treatment of skin lesions as well as gastrointestinal and respiratory disorders. This study investigated whether STH alleviates genome damage in human peripheral blood lymphocytes produced by the cytotoxic drug irinotecan. The phenolic profile of STH was previously estimated by ultra-high-performance liquid chromatography coupled to a linear ion trap–Orbitrap hybrid mass spectrometer. The effects of STH were evaluated at three concentrations (1×, 5×, and 10×), based on the daily consumption of the honey by an adult person. After 2 h of in vitro exposure, standard lymphocyte cultures for the analysis of chromosome aberrations and the cytokinesis-block micronucleus cytome assay were established. Our results demonstrate that STH offered remarkable geno- and cytoprotection when administered with irinotecan. These findings are relevant for drawing preliminary conclusions regarding the in vitro safety of the tested honey. However, further studies are needed with the application of more complex experimental models.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Supplementary material for: Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study",
volume = "24",
number = "3",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5875"
}

Jurič, A., Brčić Karačonji, I., Gašić, U. M., Milojković-Opsenica, D., Prđun, S., Bubalo, D., Lušić, D., Vahčić, N.,& Kopjar, N.. (2023). Supplementary material for: Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study. in International Journal of Molecular Sciences
MDPI., 24(3).
https://hdl.handle.net/21.15107/rcub_cherry_5875

Jurič A, Brčić Karačonji I, Gašić UM, Milojković-Opsenica D, Prđun S, Bubalo D, Lušić D, Vahčić N, Kopjar N. Supplementary material for: Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study. in International Journal of Molecular Sciences. 2023;24(3).
https://hdl.handle.net/21.15107/rcub_cherry_5875 .

Jurič, Andreja, Brčić Karačonji, Irena, Gašić, Uroš M., Milojković-Opsenica, Dušanka, Prđun, Saša, Bubalo, Dragan, Lušić, Dražen, Vahčić, Nada, Kopjar, Nevenka, "Supplementary material for: Protective Effects of Arbutus unedo L. Honey in the Alleviation of Irinotecan-Induced Cytogenetic Damage in Human Lymphocytes—An In Vitro Study" in International Journal of Molecular Sciences, 24, no. 3 (2023),
https://hdl.handle.net/21.15107/rcub_cherry_5875 .

TY  - JOUR
AU  - Zeković, Zoran P.
AU  - Smyatskaya, Yulia A.
AU  - Bazarnova, Julia G.
AU  - Pastor, Ferenc
AU  - Gorjanović, Stanislava
AU  - Gašić, Uroš M.
AU  - Pezo, Lato
AU  - Đurović, Saša
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5886
AB  - Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r2 value during the training cycle for output variables was 0.999).
PB  - MDPI
T2  - Foods
T1  - Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
VL  - 12
IS  - 4
SP  - 809
DO  - 10.3390/foods12040809
ER  - 

@article{
author = "Zeković, Zoran P. and Smyatskaya, Yulia A. and Bazarnova, Julia G. and Pastor, Ferenc and Gorjanović, Stanislava and Gašić, Uroš M. and Pezo, Lato and Đurović, Saša",
year = "2023",
abstract = "Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r2 value during the training cycle for output variables was 0.999).",
publisher = "MDPI",
journal = "Foods",
title = "Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction",
volume = "12",
number = "4",
pages = "809",
doi = "10.3390/foods12040809"
}

Zeković, Z. P., Smyatskaya, Y. A., Bazarnova, J. G., Pastor, F., Gorjanović, S., Gašić, U. M., Pezo, L.,& Đurović, S.. (2023). Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. in Foods
MDPI., 12(4), 809.
https://doi.org/10.3390/foods12040809

Zeković ZP, Smyatskaya YA, Bazarnova JG, Pastor F, Gorjanović S, Gašić UM, Pezo L, Đurović S. Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. in Foods. 2023;12(4):809.
doi:10.3390/foods12040809 .

Zeković, Zoran P., Smyatskaya, Yulia A., Bazarnova, Julia G., Pastor, Ferenc, Gorjanović, Stanislava, Gašić, Uroš M., Pezo, Lato, Đurović, Saša, "Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction" in Foods, 12, no. 4 (2023):809,
https://doi.org/10.3390/foods12040809 . .

TY  - JOUR
AU  - Milutinović, Milica
AU  - Nakarada, Đura
AU  - Božunović, Jelena
AU  - Todorović, Miloš
AU  - Gašić, Uroš M.
AU  - Živković, Suzana
AU  - Skorić, Marijana
AU  - Ivković, Đurđa
AU  - Savić, Jelena
AU  - Devrnja, Nina
AU  - Aničić, Neda
AU  - Banjanac, Tijana
AU  - Mojović, Miloš
AU  - Mišić, Danijela
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5896
AB  - The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.
PB  - MDPI
T2  - Antioxidants
T2  - Antioxidants
T1  - Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening
VL  - 12
IS  - 2
SP  - 346
DO  - 10.3390/antiox12020346
ER  - 

@article{
author = "Milutinović, Milica and Nakarada, Đura and Božunović, Jelena and Todorović, Miloš and Gašić, Uroš M. and Živković, Suzana and Skorić, Marijana and Ivković, Đurđa and Savić, Jelena and Devrnja, Nina and Aničić, Neda and Banjanac, Tijana and Mojović, Miloš and Mišić, Danijela",
year = "2023",
abstract = "The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.",
publisher = "MDPI",
journal = "Antioxidants, Antioxidants",
title = "Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening",
volume = "12",
number = "2",
pages = "346",
doi = "10.3390/antiox12020346"
}

Milutinović, M., Nakarada, Đ., Božunović, J., Todorović, M., Gašić, U. M., Živković, S., Skorić, M., Ivković, Đ., Savić, J., Devrnja, N., Aničić, N., Banjanac, T., Mojović, M.,& Mišić, D.. (2023). Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening. in Antioxidants
MDPI., 12(2), 346.
https://doi.org/10.3390/antiox12020346

Milutinović M, Nakarada Đ, Božunović J, Todorović M, Gašić UM, Živković S, Skorić M, Ivković Đ, Savić J, Devrnja N, Aničić N, Banjanac T, Mojović M, Mišić D. Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening. in Antioxidants. 2023;12(2):346.
doi:10.3390/antiox12020346 .

Milutinović, Milica, Nakarada, Đura, Božunović, Jelena, Todorović, Miloš, Gašić, Uroš M., Živković, Suzana, Skorić, Marijana, Ivković, Đurđa, Savić, Jelena, Devrnja, Nina, Aničić, Neda, Banjanac, Tijana, Mojović, Miloš, Mišić, Danijela, "Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening" in Antioxidants, 12, no. 2 (2023):346,
https://doi.org/10.3390/antiox12020346 . .

TY  - JOUR
AU  - Đurović, Saša
AU  - Micić, Darko
AU  - Šorgić, Saša
AU  - Popov, Saša
AU  - Gašić, Uroš M.
AU  - Tosti, Tomislav
AU  - Kostić, Marija
AU  - Smyatskaya, Yulia A.
AU  - Blagojević, Stevan
AU  - Zeković, Zoran
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6183
AB  - Stinging nettle (SN) is an extraordinary plant from the Urticaceae botanical family. It is well-known and widely used in food and folk medicine to treat different disorders and diseases. This article aimed to study the chemical composition of SN leaves extracts, i.e., polyphenolic compounds and vitamins B and C, because many studies ascribed high biological potency to these compounds and their significance in the human diet. Besides the chemical profile, the thermal properties of the extracts were studied. The results confirmed presence of many polyphenolic compounds and vitamins B and C. It also showed that the chemical profile closely correlated with the applied extraction technique. The thermal analysis showed that analyzed samples were thermally stable up to about 160 °C. Thermal degradation of samples UAE, MAE, and MAC took place in four steps, and sample SE in three steps. Altogether, results confirmed the presence of health-beneficial compounds in stinging nettle leaves and indicated the possible application of its extract in pharmaceutical and food industries as both a medicinal and food additive.
PB  - MDPI
T2  - Molecules
T1  - Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts
VL  - 28
IS  - 5
SP  - 2278
DO  - 10.3390/molecules28052278
ER  - 

@article{
author = "Đurović, Saša and Micić, Darko and Šorgić, Saša and Popov, Saša and Gašić, Uroš M. and Tosti, Tomislav and Kostić, Marija and Smyatskaya, Yulia A. and Blagojević, Stevan and Zeković, Zoran",
year = "2023",
abstract = "Stinging nettle (SN) is an extraordinary plant from the Urticaceae botanical family. It is well-known and widely used in food and folk medicine to treat different disorders and diseases. This article aimed to study the chemical composition of SN leaves extracts, i.e., polyphenolic compounds and vitamins B and C, because many studies ascribed high biological potency to these compounds and their significance in the human diet. Besides the chemical profile, the thermal properties of the extracts were studied. The results confirmed presence of many polyphenolic compounds and vitamins B and C. It also showed that the chemical profile closely correlated with the applied extraction technique. The thermal analysis showed that analyzed samples were thermally stable up to about 160 °C. Thermal degradation of samples UAE, MAE, and MAC took place in four steps, and sample SE in three steps. Altogether, results confirmed the presence of health-beneficial compounds in stinging nettle leaves and indicated the possible application of its extract in pharmaceutical and food industries as both a medicinal and food additive.",
publisher = "MDPI",
journal = "Molecules",
title = "Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts",
volume = "28",
number = "5",
pages = "2278",
doi = "10.3390/molecules28052278"
}

Đurović, S., Micić, D., Šorgić, S., Popov, S., Gašić, U. M., Tosti, T., Kostić, M., Smyatskaya, Y. A., Blagojević, S.,& Zeković, Z.. (2023). Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. in Molecules
MDPI., 28(5), 2278.
https://doi.org/10.3390/molecules28052278

Đurović S, Micić D, Šorgić S, Popov S, Gašić UM, Tosti T, Kostić M, Smyatskaya YA, Blagojević S, Zeković Z. Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. in Molecules. 2023;28(5):2278.
doi:10.3390/molecules28052278 .

Đurović, Saša, Micić, Darko, Šorgić, Saša, Popov, Saša, Gašić, Uroš M., Tosti, Tomislav, Kostić, Marija, Smyatskaya, Yulia A., Blagojević, Stevan, Zeković, Zoran, "Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts" in Molecules, 28, no. 5 (2023):2278,
https://doi.org/10.3390/molecules28052278 . .

TY  - THES
AU  - Stjepanović, Aleksandra
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5769
AB  - Proučavanje bioloških metoda za uklanjanja organskih zagađujućih supstanci iz vode je deo više decenijskih istraživanja Grupe za mikrobiološku hemiju i biotehnologiju, čiji saradnici rade na Univerzitetu u Beogradu i to na Hemijskom fakultetu i Centru za hemiju, Instituta za hemiju, tehnologiju i metalurgiju. Suspendovane u vodi, organski polutanti često nisu lako dostupni mikroorganizmima pa se s toga pribegava upotrebi sorpcionih agenasa. Izbor supstrata koji će za sebe vezati organske polutante često je povezan sa njegovom cenom i dostupnošću pa se u poslednje vreme pored sve prisutnog aktivnog uglja upotrebljava i otpad iz poljoprivredne i drvno-prerađivačke industrije, kao i organozeolit i bentonit.
U ovom radu proučavana je upotreba organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima uz praćenje procesa na respirometru, kompjuterizovanom sistemu za detekciju utroška i oslobađanja selektovanih gasova.
T1  - Proučavanje upotrebe organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima-studija na respirometru
SP  - 2
EP  - 37
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5769
ER  - 

@misc{
author = "Stjepanović, Aleksandra",
year = "2023",
abstract = "Proučavanje bioloških metoda za uklanjanja organskih zagađujućih supstanci iz vode je deo više decenijskih istraživanja Grupe za mikrobiološku hemiju i biotehnologiju, čiji saradnici rade na Univerzitetu u Beogradu i to na Hemijskom fakultetu i Centru za hemiju, Instituta za hemiju, tehnologiju i metalurgiju. Suspendovane u vodi, organski polutanti često nisu lako dostupni mikroorganizmima pa se s toga pribegava upotrebi sorpcionih agenasa. Izbor supstrata koji će za sebe vezati organske polutante često je povezan sa njegovom cenom i dostupnošću pa se u poslednje vreme pored sve prisutnog aktivnog uglja upotrebljava i otpad iz poljoprivredne i drvno-prerađivačke industrije, kao i organozeolit i bentonit.
U ovom radu proučavana je upotreba organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima uz praćenje procesa na respirometru, kompjuterizovanom sistemu za detekciju utroška i oslobađanja selektovanih gasova.",
title = "Proučavanje upotrebe organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima-studija na respirometru",
pages = "2-37",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5769"
}

Stjepanović, A.. (2023). Proučavanje upotrebe organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima-studija na respirometru. , 2-37.
https://hdl.handle.net/21.15107/rcub_cherry_5769

Stjepanović A. Proučavanje upotrebe organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima-studija na respirometru. 2023;:2-37.
https://hdl.handle.net/21.15107/rcub_cherry_5769 .

Stjepanović, Aleksandra, "Proučavanje upotrebe organozeolita i bentonita u postupcima bioremedijacije vode zagađene naftnim derivatima-studija na respirometru" (2023):2-37,
https://hdl.handle.net/21.15107/rcub_cherry_5769 .

TY  - THES
AU  - Ćukić, Aleksandra
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5799
AB  - Upotreba fosilnih goriva i razvoj industrije doveli su do intenzivnog zagađenja vodenih ekosistema
teškim metalima među kojima je i nikl. Prisustvo nikla u većim količinama u vodenoj sredini može
da dovede do oksidativnog stresa kod zelenih algi. Mikroalge su prepoznate kao dobar model
zahvaljujući neenzimskom i enzimskom mehanizmu odbrane od ROS-a.
Uzgojem mikroalge Chlorella sorokiniana i tretmanima jonima nikla dobijen je adekvatan materijal
za analizu pomoću Western blot metode. Na ovaj način detektovani su nivoi FeSOD, CAT i
MnSOD u ćelijskim ekstraktima, kontrolnim i tretiranim niklom.
T1  - Uticaj povećane koncentracije jona Ni(II) na nivo antioksidativnih enzima u jednoćelijskoj algi Chlorella sorokiniana
SP  - 2
EP  - 38
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5799
ER  - 

@misc{
author = "Ćukić, Aleksandra",
year = "2023",
abstract = "Upotreba fosilnih goriva i razvoj industrije doveli su do intenzivnog zagađenja vodenih ekosistema
teškim metalima među kojima je i nikl. Prisustvo nikla u većim količinama u vodenoj sredini može
da dovede do oksidativnog stresa kod zelenih algi. Mikroalge su prepoznate kao dobar model
zahvaljujući neenzimskom i enzimskom mehanizmu odbrane od ROS-a.
Uzgojem mikroalge Chlorella sorokiniana i tretmanima jonima nikla dobijen je adekvatan materijal
za analizu pomoću Western blot metode. Na ovaj način detektovani su nivoi FeSOD, CAT i
MnSOD u ćelijskim ekstraktima, kontrolnim i tretiranim niklom.",
title = "Uticaj povećane koncentracije jona Ni(II) na nivo antioksidativnih enzima u jednoćelijskoj algi Chlorella sorokiniana",
pages = "2-38",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5799"
}

Ćukić, A.. (2023). Uticaj povećane koncentracije jona Ni(II) na nivo antioksidativnih enzima u jednoćelijskoj algi Chlorella sorokiniana. , 2-38.
https://hdl.handle.net/21.15107/rcub_cherry_5799

Ćukić A. Uticaj povećane koncentracije jona Ni(II) na nivo antioksidativnih enzima u jednoćelijskoj algi Chlorella sorokiniana. 2023;:2-38.
https://hdl.handle.net/21.15107/rcub_cherry_5799 .

Ćukić, Aleksandra, "Uticaj povećane koncentracije jona Ni(II) na nivo antioksidativnih enzima u jednoćelijskoj algi Chlorella sorokiniana" (2023):2-38,
https://hdl.handle.net/21.15107/rcub_cherry_5799 .

TY  - THES
AU  - Ganić, Tijana
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5861
AB  - Izolovanje mikroorganizama iz zemljišta obogaćenog PU i kontrolnog zemljišta direktnim zasejavanjem na podloge sa Impranilom (Imp).
Detaljnije ispitivanje potencijala odabranih sojeva za razgradnju Imp, PCL i PU. Identifikacija i klasifikacija svih odabranih i izolovanih sojeva sekvenciranjem gena za 16s ribozomalnu RNK i utvrđivanje njihove međusobne srodnosti.
Odabir najefikasnijih sojeva i određivanje procenta degradacije Imp u tečnim kulturama.
T1  - Biokatalitički potencijal odabranih izolata za razgradnju poliuretana
SP  - 1
EP  - 45
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5861
ER  - 

@mastersthesis{
author = "Ganić, Tijana",
year = "2023",
abstract = "Izolovanje mikroorganizama iz zemljišta obogaćenog PU i kontrolnog zemljišta direktnim zasejavanjem na podloge sa Impranilom (Imp).
Detaljnije ispitivanje potencijala odabranih sojeva za razgradnju Imp, PCL i PU. Identifikacija i klasifikacija svih odabranih i izolovanih sojeva sekvenciranjem gena za 16s ribozomalnu RNK i utvrđivanje njihove međusobne srodnosti.
Odabir najefikasnijih sojeva i određivanje procenta degradacije Imp u tečnim kulturama.",
title = "Biokatalitički potencijal odabranih izolata za razgradnju poliuretana",
pages = "1-45",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5861"
}

Ganić, T.. (2023). Biokatalitički potencijal odabranih izolata za razgradnju poliuretana. , 1-45.
https://hdl.handle.net/21.15107/rcub_cherry_5861

Ganić T. Biokatalitički potencijal odabranih izolata za razgradnju poliuretana. 2023;:1-45.
https://hdl.handle.net/21.15107/rcub_cherry_5861 .

Ganić, Tijana, "Biokatalitički potencijal odabranih izolata za razgradnju poliuretana" (2023):1-45,
https://hdl.handle.net/21.15107/rcub_cherry_5861 .

TY  - THES
AU  - Vukadinović, Marija
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5905
AB  - Cilj ovog rada jeste da se ispita sposobnost mikroorganizma Acidithiobacillus 
ferrooxidans za procese luženja. Studija je rađena na dva supstrata, boksitu i crvenom mulju.
Boksit kao primarna ruda aluminijuma, a crveni mulj kao otpadni proizvod su idealni odabir za 
ovu studiju bioluženja jer tradicionalne tehnike odlaganja crvenog mulja kao što su 
deponovanje ili skladištenje mogu da prouzrokuju veliku štetu za životnu sredinu.
 Bioluženje je proces koji koristi mikroorganizme za ekstrakciju metala iz ruda i 
otpadnih materijala, a njegov značaj leži u potencijalu mikroorganizama da "povrate" vredne 
elemente iz otpadnih materijala, čime se smanjuje njihov štetni efekat na životnu sredinu, dok 
se istovremeno dobijaju vredni metali koji se mogu dalje koristiti.
T1  - Analiza luženja crvenog mulja i boksita upotrebom bakterije  Acidithiobacillus ferrooxidans
SP  - 6
EP  - 48
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5905
ER  - 

@misc{
author = "Vukadinović, Marija",
year = "2023",
abstract = "Cilj ovog rada jeste da se ispita sposobnost mikroorganizma Acidithiobacillus 
ferrooxidans za procese luženja. Studija je rađena na dva supstrata, boksitu i crvenom mulju.
Boksit kao primarna ruda aluminijuma, a crveni mulj kao otpadni proizvod su idealni odabir za 
ovu studiju bioluženja jer tradicionalne tehnike odlaganja crvenog mulja kao što su 
deponovanje ili skladištenje mogu da prouzrokuju veliku štetu za životnu sredinu.
 Bioluženje je proces koji koristi mikroorganizme za ekstrakciju metala iz ruda i 
otpadnih materijala, a njegov značaj leži u potencijalu mikroorganizama da "povrate" vredne 
elemente iz otpadnih materijala, čime se smanjuje njihov štetni efekat na životnu sredinu, dok 
se istovremeno dobijaju vredni metali koji se mogu dalje koristiti.",
title = "Analiza luženja crvenog mulja i boksita upotrebom bakterije  Acidithiobacillus ferrooxidans",
pages = "6-48",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5905"
}

Vukadinović, M.. (2023). Analiza luženja crvenog mulja i boksita upotrebom bakterije  Acidithiobacillus ferrooxidans. , 6-48.
https://hdl.handle.net/21.15107/rcub_cherry_5905

Vukadinović M. Analiza luženja crvenog mulja i boksita upotrebom bakterije  Acidithiobacillus ferrooxidans. 2023;:6-48.
https://hdl.handle.net/21.15107/rcub_cherry_5905 .

Vukadinović, Marija, "Analiza luženja crvenog mulja i boksita upotrebom bakterije  Acidithiobacillus ferrooxidans" (2023):6-48,
https://hdl.handle.net/21.15107/rcub_cherry_5905 .

TY  - GEN
AU  - Beškoski, Vladimir
AU  - Lješević, Marija
AU  - Lončarević, Branka
AU  - Božić, Tatjana T.
AU  - Relić, Dubravka
AU  - Vujisić, Ljubodrag V.
AU  - Gruden-Pavlović, Maja
AU  - Lugonja, Nikoleta
AU  - Jiménez, Begoña
AU  - Colomer Vidal, Pere
AU  - Muñoz Arnanz, Juan
AU  - Battaglia, Fabienne
AU  - Crampon, Marc
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6048
AB  - Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals that have been widely used in various industrial and consumer products due to their unique properties, such as oil and water repellency, thermal stability, and durability. However, the persistence and mobility of these chemicals in the environment have raised concerns about their potential adverse effects on human health and the environment. PFAS have been detected on a global scale in various environmental media, such as soil, water, air, and biota. As a country undergoing economic development and transition, Serbia faces the challenge of managing and addressing the PFAS contamination in its environment. This challenge requires a comprehensive and science-based strategy that can effectively reduce the exposure and risks of PFAS to human health and the environment. This document aims to provide a scientific strategy for solving the PFAS challenge in Serbia. Firstly, it is important to acknowledge that PFAS are persistent and bioaccumulative in the environment, which means that they do not break down easily and can accumulate in the food chain, posing a long-term risk to human health and the environment. Therefore, a precautionary approach is necessary to minimize the exposure and risks of PFAS. International experience and cooperation are very important for developing an effective scientifc strategy for addressing the PFAS challenge in Serbia. PFAS are a global issue, and many countries have already implemented measures to manage and reduce the exposure and risks of PFAS. Therefore, it is important to draw on international experience and best practices when developing the strategy for Serbia. International experience can provide valuable insights into the sources, pathways, and fate of PFAS, as well as the e"ectiveness of various risk management measures. For example, the United States, Canada, and some European countries have established regulatory frameworks for PFAS, which can serve as a model for Serbia. Other countries have implemented remediation measures for contaminated sites, which can provide valuable insights for selecting appropriate remediation technologies in Serbia. Moreover, international experience can provide access to the latest scientific knowledge, methods, and technologies for assessing and managing PFAS contamination. For example, international organizations such as the United Nations Environment Programme (UNEP) and the Organization for Economic Co-operation and Development (OECD) have developed guidance documents and tools for assessing and managing PFAS contamination. The scientific strategy for solving the PFAS challenge in Serbia is based on a thorough understanding of the sources, pathways, and fate of PFAS in the environment. It is also based on a comprehensive and systematic approach, including risk assessment, monitoring, regulation, remediation, and communication. This strategy is tailored to the specific context and needs of Serbia. It is based on the latest scientifc knowledge and practical experience from other countries and regions, focusing on the European Union, USA, China and Japan. The cultural, social, economic, and political factors can affect the implementation and effectiveness of the strategy, and therefore, the strategy is developed through a collaborative and participatory process involving stakeholders from different sectors and levels. The international experience provided helpful guidance and lessons learned, but ultimately, the strategy is based on local knowledge, priorities, and capacities. By implementing this strategy, we aim to contribute to that Serbia can protect its citizens and environment from the potential harm of PFAS and achieve sustainable development.
PB  - University of Belgrade – Faculty of Chemistry
T1  - Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033)
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6048
ER  - 

@misc{
author = "Beškoski, Vladimir and Lješević, Marija and Lončarević, Branka and Božić, Tatjana T. and Relić, Dubravka and Vujisić, Ljubodrag V. and Gruden-Pavlović, Maja and Lugonja, Nikoleta and Jiménez, Begoña and Colomer Vidal, Pere and Muñoz Arnanz, Juan and Battaglia, Fabienne and Crampon, Marc",
year = "2023",
abstract = "Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals that have been widely used in various industrial and consumer products due to their unique properties, such as oil and water repellency, thermal stability, and durability. However, the persistence and mobility of these chemicals in the environment have raised concerns about their potential adverse effects on human health and the environment. PFAS have been detected on a global scale in various environmental media, such as soil, water, air, and biota. As a country undergoing economic development and transition, Serbia faces the challenge of managing and addressing the PFAS contamination in its environment. This challenge requires a comprehensive and science-based strategy that can effectively reduce the exposure and risks of PFAS to human health and the environment. This document aims to provide a scientific strategy for solving the PFAS challenge in Serbia. Firstly, it is important to acknowledge that PFAS are persistent and bioaccumulative in the environment, which means that they do not break down easily and can accumulate in the food chain, posing a long-term risk to human health and the environment. Therefore, a precautionary approach is necessary to minimize the exposure and risks of PFAS. International experience and cooperation are very important for developing an effective scientifc strategy for addressing the PFAS challenge in Serbia. PFAS are a global issue, and many countries have already implemented measures to manage and reduce the exposure and risks of PFAS. Therefore, it is important to draw on international experience and best practices when developing the strategy for Serbia. International experience can provide valuable insights into the sources, pathways, and fate of PFAS, as well as the e"ectiveness of various risk management measures. For example, the United States, Canada, and some European countries have established regulatory frameworks for PFAS, which can serve as a model for Serbia. Other countries have implemented remediation measures for contaminated sites, which can provide valuable insights for selecting appropriate remediation technologies in Serbia. Moreover, international experience can provide access to the latest scientific knowledge, methods, and technologies for assessing and managing PFAS contamination. For example, international organizations such as the United Nations Environment Programme (UNEP) and the Organization for Economic Co-operation and Development (OECD) have developed guidance documents and tools for assessing and managing PFAS contamination. The scientific strategy for solving the PFAS challenge in Serbia is based on a thorough understanding of the sources, pathways, and fate of PFAS in the environment. It is also based on a comprehensive and systematic approach, including risk assessment, monitoring, regulation, remediation, and communication. This strategy is tailored to the specific context and needs of Serbia. It is based on the latest scientifc knowledge and practical experience from other countries and regions, focusing on the European Union, USA, China and Japan. The cultural, social, economic, and political factors can affect the implementation and effectiveness of the strategy, and therefore, the strategy is developed through a collaborative and participatory process involving stakeholders from different sectors and levels. The international experience provided helpful guidance and lessons learned, but ultimately, the strategy is based on local knowledge, priorities, and capacities. By implementing this strategy, we aim to contribute to that Serbia can protect its citizens and environment from the potential harm of PFAS and achieve sustainable development.",
publisher = "University of Belgrade – Faculty of Chemistry",
title = "Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033)",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6048"
}

Beškoski, V., Lješević, M., Lončarević, B., Božić, T. T., Relić, D., Vujisić, L. V., Gruden-Pavlović, M., Lugonja, N., Jiménez, B., Colomer Vidal, P., Muñoz Arnanz, J., Battaglia, F.,& Crampon, M.. (2023). Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033). 
University of Belgrade – Faculty of Chemistry..
https://hdl.handle.net/21.15107/rcub_cherry_6048

Beškoski V, Lješević M, Lončarević B, Božić TT, Relić D, Vujisić LV, Gruden-Pavlović M, Lugonja N, Jiménez B, Colomer Vidal P, Muñoz Arnanz J, Battaglia F, Crampon M. Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033). 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6048 .

Beškoski, Vladimir, Lješević, Marija, Lončarević, Branka, Božić, Tatjana T., Relić, Dubravka, Vujisić, Ljubodrag V., Gruden-Pavlović, Maja, Lugonja, Nikoleta, Jiménez, Begoña, Colomer Vidal, Pere, Muñoz Arnanz, Juan, Battaglia, Fabienne, Crampon, Marc, "Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033)" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6048 .

TY  - RPRT
AU  - Jiménez, Begoña
AU  - Beškoski, Vladimir
AU  - Božić, Tatjana T.
AU  - Colomer Vidal, Pere
AU  - Muñoz Arnanz, Juan
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6060
AB  - The development of the Scientific Strategy for PFAS Analysis and Bioremediation at 
UBFC has been successfully completed through Work Package 1 of the PFAStwin project. Under this strategy, a thorough ten-year plan has been formulated. The main goal of this plan is to 
establish UBFC as a leading hub of expertise in PFAS research, fostering creative projects and cooperative efforts to tackle PFAS-related challenges. The objective of this deliverable is to create an action plan outlining the essential measures required to achieve the goals set in the ten-year plan.
T1  - D1.3 Action plan
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6060
ER  - 

@techreport{
author = "Jiménez, Begoña and Beškoski, Vladimir and Božić, Tatjana T. and Colomer Vidal, Pere and Muñoz Arnanz, Juan",
year = "2023",
abstract = "The development of the Scientific Strategy for PFAS Analysis and Bioremediation at 
UBFC has been successfully completed through Work Package 1 of the PFAStwin project. Under this strategy, a thorough ten-year plan has been formulated. The main goal of this plan is to 
establish UBFC as a leading hub of expertise in PFAS research, fostering creative projects and cooperative efforts to tackle PFAS-related challenges. The objective of this deliverable is to create an action plan outlining the essential measures required to achieve the goals set in the ten-year plan.",
title = "D1.3 Action plan",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6060"
}

Jiménez, B., Beškoski, V., Božić, T. T., Colomer Vidal, P.,& Muñoz Arnanz, J.. (2023). D1.3 Action plan. .
https://hdl.handle.net/21.15107/rcub_cherry_6060

Jiménez B, Beškoski V, Božić TT, Colomer Vidal P, Muñoz Arnanz J. D1.3 Action plan. 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6060 .

Jiménez, Begoña, Beškoski, Vladimir, Božić, Tatjana T., Colomer Vidal, Pere, Muñoz Arnanz, Juan, "D1.3 Action plan" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6060 .

TY  - RPRT
AU  - Božić, Tatjana T.
AU  - Beškoski, Vladimir
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6063
AB  - This report provides an overview of the recruitment procedure conducted for hiring additional personnel for the International Cooperation and Project Management Office at the University of Belgrade - Faculty of Chemistry within WP4 of PFAStwin project. The purpose of the recruitment process was to identify and select highly qualified candidates who possess the necessary skills and experience to contribute effectively to the office's operations and objectives.
T1  - D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6063
ER  - 

@techreport{
author = "Božić, Tatjana T. and Beškoski, Vladimir",
year = "2023",
abstract = "This report provides an overview of the recruitment procedure conducted for hiring additional personnel for the International Cooperation and Project Management Office at the University of Belgrade - Faculty of Chemistry within WP4 of PFAStwin project. The purpose of the recruitment process was to identify and select highly qualified candidates who possess the necessary skills and experience to contribute effectively to the office's operations and objectives.",
title = "D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6063"
}

Božić, T. T.,& Beškoski, V.. (2023). D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC. .
https://hdl.handle.net/21.15107/rcub_cherry_6063

Božić TT, Beškoski V. D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC. 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6063 .

Božić, Tatjana T., Beškoski, Vladimir, "D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6063 .