TY  - DATA
AU  - Penjišević, Jelena 
AU  - Šukalović, Vladimir 
AU  - Dukić-Stefanović, Slađana
AU  - Deuther-Conrad, Winnie
AU  - Andrić, Deana 
AU  - Kostić-Rajačić, Slađana
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5845
AB  - Serotonin receptors modulate numerous behavioral and neuropsychological processes. Therefore, they are the target for the action of many drugs, such as antipsychotics, antidepressants, antiemetics, migraine remedies, and many others. The 5-HT1A receptors have been involved in the pathogenesis and treatment of anxiety and depression and represent a promising target for new drugs with reduced extrapyramidal side effects. In most antidepressants, a piperazine-based structural motif can be identified as a common moiety. Here we describe the synthesis, pharmacological, and in silico characterization of a novel arylpiperazines series with excellent 5-HT1A affinity. The final compounds, 4a, 8a, and 8b, were selected according to predictions of in silico pharmacokinetics, docking analysis, and molecular dynamics in conjunction with physical properties, and metabolic stability. The accentuated molecules could serve as a lead compound for developing 5-HT1A drug-like molecules for depression treatment.
PB  - Elsevier
T2  - Arabian Journal of Chemistry
T1  - Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636
VL  - 16
IS  - 4
SP  - 104636
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5845
ER  - 

@misc{
author = "Penjišević, Jelena  and Šukalović, Vladimir  and Dukić-Stefanović, Slađana and Deuther-Conrad, Winnie and Andrić, Deana  and Kostić-Rajačić, Slađana",
abstract = "Serotonin receptors modulate numerous behavioral and neuropsychological processes. Therefore, they are the target for the action of many drugs, such as antipsychotics, antidepressants, antiemetics, migraine remedies, and many others. The 5-HT1A receptors have been involved in the pathogenesis and treatment of anxiety and depression and represent a promising target for new drugs with reduced extrapyramidal side effects. In most antidepressants, a piperazine-based structural motif can be identified as a common moiety. Here we describe the synthesis, pharmacological, and in silico characterization of a novel arylpiperazines series with excellent 5-HT1A affinity. The final compounds, 4a, 8a, and 8b, were selected according to predictions of in silico pharmacokinetics, docking analysis, and molecular dynamics in conjunction with physical properties, and metabolic stability. The accentuated molecules could serve as a lead compound for developing 5-HT1A drug-like molecules for depression treatment.",
publisher = "Elsevier",
journal = "Arabian Journal of Chemistry",
title = "Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636",
volume = "16",
number = "4",
pages = "104636",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5845"
}

Penjišević, J., Šukalović, V., Dukić-Stefanović, S., Deuther-Conrad, W., Andrić, D.,& Kostić-Rajačić, S..Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636. in Arabian Journal of Chemistry
Elsevier., 16(4), 104636.
https://hdl.handle.net/21.15107/rcub_cherry_5845

Penjišević J, Šukalović V, Dukić-Stefanović S, Deuther-Conrad W, Andrić D, Kostić-Rajačić S. Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636. in Arabian Journal of Chemistry.16(4):104636.
https://hdl.handle.net/21.15107/rcub_cherry_5845 .

Penjišević, Jelena , Šukalović, Vladimir , Dukić-Stefanović, Slađana, Deuther-Conrad, Winnie, Andrić, Deana , Kostić-Rajačić, Slađana, "Supplementary material for: Penjišević, J. Z., Šukalović, V. B., Dukic-Stefanovic, S., Deuther-Conrad, W., Andrić, D. B.,& Kostić-Rajačić, S. V.. (2023). Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency. in Arabian Journal of Chemistry Elsevier., 16(4), 104636. https://doi.org/10.1016/j.arabjc.2023.104636" in Arabian Journal of Chemistry, 16, no. 4:104636,
https://hdl.handle.net/21.15107/rcub_cherry_5845 .

TY  - DATA
AU  - Aleksić, Jovana
AU  - Stojanović, Milovan
AU  - Bošković, Jakša
AU  - Baranac-Stojanović, Marija
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5846
AB  - We present the green, highly atom-economical, solid-state silica gel-catalyzed synthesis of polysubstituted 1,4- and 1,2-dihydropyridines (DHPs) from commercially available materials, amines and ethyl propiolate. The DHP skeleton was assembled by heating the reactants and silica gel in a closed vessel. Aliphatic amines provided 1,4-isomers as the main or only DHP products, but the reactions of aromatic amines yielded a mixture of 1,4- and 1,2-isomers. To the best of our knowledge, this is the first example of the formation of a 1,2-DHP structure by the reaction of an amine with propiolic ester. Addition of 1 mass percent of H2SO4 to silica gel shifted the product distribution to 1,4-DHP as the main or the only isomer obtained. Experimental and theoretical analyses led to the identification of two key intermediates en route to DHPs and the explanation of the observed regioisomeric ratios. 1,2-DHPs show blue-cyan fluorescence in MeOH with the quantum yield Φ = 0.10–0.22 relative to quinine sulfate Φ = 0.58 and 1,4-DHPs show blue-violet fluorescence with Φ = 0.09–0.81.
PB  - Royal Society of Chemistry
T2  - Organic & Biomolecular Chemistry
T1  - Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F
VL  - 21
IS  - 6
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5846
ER  - 

@misc{
author = "Aleksić, Jovana and Stojanović, Milovan and Bošković, Jakša and Baranac-Stojanović, Marija",
abstract = "We present the green, highly atom-economical, solid-state silica gel-catalyzed synthesis of polysubstituted 1,4- and 1,2-dihydropyridines (DHPs) from commercially available materials, amines and ethyl propiolate. The DHP skeleton was assembled by heating the reactants and silica gel in a closed vessel. Aliphatic amines provided 1,4-isomers as the main or only DHP products, but the reactions of aromatic amines yielded a mixture of 1,4- and 1,2-isomers. To the best of our knowledge, this is the first example of the formation of a 1,2-DHP structure by the reaction of an amine with propiolic ester. Addition of 1 mass percent of H2SO4 to silica gel shifted the product distribution to 1,4-DHP as the main or the only isomer obtained. Experimental and theoretical analyses led to the identification of two key intermediates en route to DHPs and the explanation of the observed regioisomeric ratios. 1,2-DHPs show blue-cyan fluorescence in MeOH with the quantum yield Φ = 0.10–0.22 relative to quinine sulfate Φ = 0.58 and 1,4-DHPs show blue-violet fluorescence with Φ = 0.09–0.81.",
publisher = "Royal Society of Chemistry",
journal = "Organic & Biomolecular Chemistry",
title = "Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F",
volume = "21",
number = "6",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5846"
}

Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M..Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6).
https://hdl.handle.net/21.15107/rcub_cherry_5846

Aleksić J, Stojanović M, Bošković J, Baranac-Stojanović M. Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F. in Organic & Biomolecular Chemistry.21(6).
https://hdl.handle.net/21.15107/rcub_cherry_5846 .

Aleksić, Jovana, Stojanović, Milovan, Bošković, Jakša, Baranac-Stojanović, Marija, "Supplementary material for: Aleksić, J., Stojanović, M., Bošković, J.,& Baranac-Stojanović, M.. (2023). Solid-state silica gel-catalyzed synthesis of fluorescent polysubstituted 1,4- and 1,2-dihydropyridines. in Organic & Biomolecular Chemistry
Royal Society of Chemistry., 21(6), 1187-1205.
https://doi.org/10.1039/D2OB02119F" in Organic & Biomolecular Chemistry, 21, no. 6,
https://hdl.handle.net/21.15107/rcub_cherry_5846 .

TY  - JOUR
AU  - Nikolić, Stefan
AU  - Stanković, Dalibor
AU  - Grgurić-Šipka, Sanja
PY  - 2025
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6647
AB  - In search for antitumor metal-based drugs that would mitigate the severe side-effects of cisplatin, Ru(II) complexes
are gaining increasing recent interest. Their cytotoxic effect is widely known, however mechanism of
action, solution behavior, redox reactions within biological system are still focus of the new studies. Various
experiments and approach techniques are used to better understand ruthenium chemistry. In this order their
biological activity and the availability of reduction potential in the biological medium, it is necessary to know
their electrochemical redox behavior and properties. In this work, we report the electrochemical activity on
synthesized and characterized (1H- and 13C NMR, FT-IR, MS) half-sandwich organometallic Ru(II) complexes of
the general formula [Ru(η6-arene)(XY)Cl](PF6) where arene = benzene, toluene or p-cymene and XY = bidentates:
dipyrido[3,2-a:2′,3′-c]phenazine (dppz derivatives) or 2-(9-anthryl)-1H-imidazo[4,5-f][1,10]phenanthroline
(aip), which are bound to Ru(II) via two phenanthroline-N atoms in a characteristic “piano-stool”
configuration of Ru(II)-arene complexes – as confirmed by vibrational and NMR spectra. It is shown that selected
complexes can be divided in four groups, based on their electrochemical behavior. These behaviors are correlated
with their structure and nature of ligands.
PB  - Elsevier
T2  - Inorganica Chimica Acta
T1  - Electrochemistry of different ruthenium polypyridine complexes
VL  - 574
SP  - 122352
DO  - 10.1016/j.ica.2024.122352
ER  - 

@article{
author = "Nikolić, Stefan and Stanković, Dalibor and Grgurić-Šipka, Sanja",
year = "2025",
abstract = "In search for antitumor metal-based drugs that would mitigate the severe side-effects of cisplatin, Ru(II) complexes
are gaining increasing recent interest. Their cytotoxic effect is widely known, however mechanism of
action, solution behavior, redox reactions within biological system are still focus of the new studies. Various
experiments and approach techniques are used to better understand ruthenium chemistry. In this order their
biological activity and the availability of reduction potential in the biological medium, it is necessary to know
their electrochemical redox behavior and properties. In this work, we report the electrochemical activity on
synthesized and characterized (1H- and 13C NMR, FT-IR, MS) half-sandwich organometallic Ru(II) complexes of
the general formula [Ru(η6-arene)(XY)Cl](PF6) where arene = benzene, toluene or p-cymene and XY = bidentates:
dipyrido[3,2-a:2′,3′-c]phenazine (dppz derivatives) or 2-(9-anthryl)-1H-imidazo[4,5-f][1,10]phenanthroline
(aip), which are bound to Ru(II) via two phenanthroline-N atoms in a characteristic “piano-stool”
configuration of Ru(II)-arene complexes – as confirmed by vibrational and NMR spectra. It is shown that selected
complexes can be divided in four groups, based on their electrochemical behavior. These behaviors are correlated
with their structure and nature of ligands.",
publisher = "Elsevier",
journal = "Inorganica Chimica Acta",
title = "Electrochemistry of different ruthenium polypyridine complexes",
volume = "574",
pages = "122352",
doi = "10.1016/j.ica.2024.122352"
}

Nikolić, S., Stanković, D.,& Grgurić-Šipka, S.. (2025). Electrochemistry of different ruthenium polypyridine complexes. in Inorganica Chimica Acta
Elsevier., 574, 122352.
https://doi.org/10.1016/j.ica.2024.122352

Nikolić S, Stanković D, Grgurić-Šipka S. Electrochemistry of different ruthenium polypyridine complexes. in Inorganica Chimica Acta. 2025;574:122352.
doi:10.1016/j.ica.2024.122352 .

Nikolić, Stefan, Stanković, Dalibor, Grgurić-Šipka, Sanja, "Electrochemistry of different ruthenium polypyridine complexes" in Inorganica Chimica Acta, 574 (2025):122352,
https://doi.org/10.1016/j.ica.2024.122352 . .

TY  - JOUR
AU  - Mirković, Marija
AU  - Belaj, Ferdinand
AU  - Perić, Marko
AU  - Stanković, Dalibor
AU  - Radović, Magdalena
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Cvijetić, Ilija
AU  - Mihajlović-Lalić, Ljiljana E.
PY  - 2025
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6636
T2  - Journal of Molecular Structure
T2  - Journal of Molecular Structure
T1  - Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical
VL  - 1321
SP  - 139791
DO  - 10.1016/j.molstruc.2024.139791
ER  - 

@article{
author = "Mirković, Marija and Belaj, Ferdinand and Perić, Marko and Stanković, Dalibor and Radović, Magdalena and Milanović, Zorana and Vranješ-Đurić, Sanja and Janković, Drina and Cvijetić, Ilija and Mihajlović-Lalić, Ljiljana E.",
year = "2025",
journal = "Journal of Molecular Structure, Journal of Molecular Structure",
title = "Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical",
volume = "1321",
pages = "139791",
doi = "10.1016/j.molstruc.2024.139791"
}

Mirković, M., Belaj, F., Perić, M., Stanković, D., Radović, M., Milanović, Z., Vranješ-Đurić, S., Janković, D., Cvijetić, I.,& Mihajlović-Lalić, L. E.. (2025). Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical. in Journal of Molecular Structure, 1321, 139791.
https://doi.org/10.1016/j.molstruc.2024.139791

Mirković M, Belaj F, Perić M, Stanković D, Radović M, Milanović Z, Vranješ-Đurić S, Janković D, Cvijetić I, Mihajlović-Lalić LE. Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical. in Journal of Molecular Structure. 2025;1321:139791.
doi:10.1016/j.molstruc.2024.139791 .

Mirković, Marija, Belaj, Ferdinand, Perić, Marko, Stanković, Dalibor, Radović, Magdalena, Milanović, Zorana, Vranješ-Đurić, Sanja, Janković, Drina, Cvijetić, Ilija, Mihajlović-Lalić, Ljiljana E., "Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical" in Journal of Molecular Structure, 1321 (2025):139791,
https://doi.org/10.1016/j.molstruc.2024.139791 . .

TY  - GEN
AU  - Шишаковић, Исидора
AU  - Мирковић, Ања
AU  - Радовановић, Мина
AU  - Крмпота, Ивана
AU  - Шкиљевић, Романа
AU  - Цветковић, Јован
AU  - Савић, Слађана Д.
AU  - Деновић, Вања
AU  - Симеуновић, Бојана
AU  - Арсенијевић, Марија
AU  - Лазовић, Марина
AU  - Вујновић, Милица
AU  - Ћирић, Теодора
AU  - Станков, Јелена
AU  - Јакановски, Михајло
AU  - Лазовић, Мила
AU  - Кесић, Јелена
PY  - 2024
UR  - http://chem.bg.ac.rs/studorg/
UR  - https://www.facebook.com/pozitroncasopis/
UR  - https://www.instagram.com/pozitroncasopis/
UR  - pozitron@chem.bg.ac.rs
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6531
AB  - На самом почетку броја, подсећамо се овогодишњеманифестације Global Women’s Breakfast, одржане у фебруару. Даље се упознајемо са радом организације Лицеулице. Студенткиња мастер студија Романа Шкиљевић представља Иновациони инкубатор, а Јован Цветковић се осврће на Дан отворених врата Хемијског факултета одржан у марту. Разговарамо са Наталијом Грујић, студенткињом Новинарства на Факултету политичких наука, а такође чланицом редакције њиховог студентског медија, Слушаонице 6, као и са студенткињом докторских академских студија у области биохемијских наука и генералном  секретарком Биохемијског друштва Србије, Исидором Протић Росић у оквиру рубрике Укратко о подугачком. У овом броју можете да откријете и нешто више о најстаријем предмету на Хемијском факултету, јеличком метеориту. Још један од наших саговорника је др Алекс Авдиф, гостујући виши сарадник на Кингс колеџу у Лондону и аутор књиге Absorption and Drug Development. Студенти Хемије животне средине нам приказују како изгледа теренска настава у оквиру изборног предмета на завршним годинама студија, Природни ресурси. Пишемо и о другом по реду Фестивалу хемије, одржаном у организацији Клуба младих хемичара Србије и Српског хемијског друштва. Препоруку за добру књигу можете да пронађете у Позитроновој листи омиљених књига, а најновије вести из хемије и студентског живота пточитајте у Ретросинтези. За крај, насмејте се кроз Позитиву и уживајте у броју пред вама.
PB  - Универзитет у Београду – Хемијски факултет
T1  - Позитрон - 33
VL  - 33
SP  - 1
EP  - 26
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6531
ER  - 

@misc{
author = "Шишаковић, Исидора and Мирковић, Ања and Радовановић, Мина and Крмпота, Ивана and Шкиљевић, Романа and Цветковић, Јован and Савић, Слађана Д. and Деновић, Вања and Симеуновић, Бојана and Арсенијевић, Марија and Лазовић, Марина and Вујновић, Милица and Ћирић, Теодора and Станков, Јелена and Јакановски, Михајло and Лазовић, Мила and Кесић, Јелена",
year = "2024",
abstract = "На самом почетку броја, подсећамо се овогодишњеманифестације Global Women’s Breakfast, одржане у фебруару. Даље се упознајемо са радом организације Лицеулице. Студенткиња мастер студија Романа Шкиљевић представља Иновациони инкубатор, а Јован Цветковић се осврће на Дан отворених врата Хемијског факултета одржан у марту. Разговарамо са Наталијом Грујић, студенткињом Новинарства на Факултету политичких наука, а такође чланицом редакције њиховог студентског медија, Слушаонице 6, као и са студенткињом докторских академских студија у области биохемијских наука и генералном  секретарком Биохемијског друштва Србије, Исидором Протић Росић у оквиру рубрике Укратко о подугачком. У овом броју можете да откријете и нешто више о најстаријем предмету на Хемијском факултету, јеличком метеориту. Још један од наших саговорника је др Алекс Авдиф, гостујући виши сарадник на Кингс колеџу у Лондону и аутор књиге Absorption and Drug Development. Студенти Хемије животне средине нам приказују како изгледа теренска настава у оквиру изборног предмета на завршним годинама студија, Природни ресурси. Пишемо и о другом по реду Фестивалу хемије, одржаном у организацији Клуба младих хемичара Србије и Српског хемијског друштва. Препоруку за добру књигу можете да пронађете у Позитроновој листи омиљених књига, а најновије вести из хемије и студентског живота пточитајте у Ретросинтези. За крај, насмејте се кроз Позитиву и уживајте у броју пред вама.",
publisher = "Универзитет у Београду – Хемијски факултет",
title = "Позитрон - 33",
volume = "33",
pages = "1-26",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6531"
}

Шишаковић, И., Мирковић, А., Радовановић, М., Крмпота, И., Шкиљевић, Р., Цветковић, Ј., Савић, С. Д., Деновић, В., Симеуновић, Б., Арсенијевић, М., Лазовић, М., Вујновић, М., Ћирић, Т., Станков, Ј., Јакановски, М., Лазовић, М.,& Кесић, Ј.. (2024). Позитрон - 33. 
Универзитет у Београду – Хемијски факултет., 33, 1-26.
https://hdl.handle.net/21.15107/rcub_cherry_6531

Шишаковић И, Мирковић А, Радовановић М, Крмпота И, Шкиљевић Р, Цветковић Ј, Савић СД, Деновић В, Симеуновић Б, Арсенијевић М, Лазовић М, Вујновић М, Ћирић Т, Станков Ј, Јакановски М, Лазовић М, Кесић Ј. Позитрон - 33. 2024;33:1-26.
https://hdl.handle.net/21.15107/rcub_cherry_6531 .

Шишаковић, Исидора, Мирковић, Ања, Радовановић, Мина, Крмпота, Ивана, Шкиљевић, Романа, Цветковић, Јован, Савић, Слађана Д., Деновић, Вања, Симеуновић, Бојана, Арсенијевић, Марија, Лазовић, Марина, Вујновић, Милица, Ћирић, Теодора, Станков, Јелена, Јакановски, Михајло, Лазовић, Мила, Кесић, Јелена, "Позитрон - 33", 33 (2024):1-26,
https://hdl.handle.net/21.15107/rcub_cherry_6531 .

TY  - JOUR
AU  - Милановић Маштраповић, Весна Д.
AU  - Савић, Слађана Д.
AU  - Софренић, Ивана В.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6567
AB  - У октобру 2023. године обележено је 170 година од када је на Лицеју одржано прво предавање из хемије, и тиме исписане прве странице историје модерне хемије у Србији. Како бисмо боље разумели садашњи тренутак и сагледали развијеност хемије као науке на Универзитету у Београду – Хемијском факултету, вратимо се у време и околности у којима су постављени темељи хемије у Србији. У другом делу чланка дат је опис данашњег стања на Универзитету у Београду – Хемијском факултету.
AB  - In October 2023, we marked 170 years since the first chemistry lecture was held at the Lyceum, when the first pages of the history of modern chemistry in Serbia was written. In order to better understand the present moment and percieve the development of chemistry as a science at
the University of Belgrade – Faculty of Chemistry, we went back to the time and circumstances in which the foundations of chemistry in Serbia were posted. In the second part of the article, description of today’s state at the University of Belgrade – Faculty of Chemistry was provided.
PB  - Београд : Српско хемијско друштво
T2  - Хемијски преглед
T1  - Кратка прича о 170 година хемије у Србији и Хемијском факултету Универзитета у Београду
T1  - A short story about 170 years of chemistry in Serbia and University of Belgrade – Faculty of chemistry
IS  - 65
IS  - 2
SP  - 41
EP  - 44
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6567
ER  - 

@article{
author = "Милановић Маштраповић, Весна Д. and Савић, Слађана Д. and Софренић, Ивана В.",
year = "2024",
abstract = "У октобру 2023. године обележено је 170 година од када је на Лицеју одржано прво предавање из хемије, и тиме исписане прве странице историје модерне хемије у Србији. Како бисмо боље разумели садашњи тренутак и сагледали развијеност хемије као науке на Универзитету у Београду – Хемијском факултету, вратимо се у време и околности у којима су постављени темељи хемије у Србији. У другом делу чланка дат је опис данашњег стања на Универзитету у Београду – Хемијском факултету., In October 2023, we marked 170 years since the first chemistry lecture was held at the Lyceum, when the first pages of the history of modern chemistry in Serbia was written. In order to better understand the present moment and percieve the development of chemistry as a science at
the University of Belgrade – Faculty of Chemistry, we went back to the time and circumstances in which the foundations of chemistry in Serbia were posted. In the second part of the article, description of today’s state at the University of Belgrade – Faculty of Chemistry was provided.",
publisher = "Београд : Српско хемијско друштво",
journal = "Хемијски преглед",
title = "Кратка прича о 170 година хемије у Србији и Хемијском факултету Универзитета у Београду, A short story about 170 years of chemistry in Serbia and University of Belgrade – Faculty of chemistry",
number = "65, 2",
pages = "41-44",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6567"
}

Милановић Маштраповић, В. Д., Савић, С. Д.,& Софренић, И. В.. (2024). Кратка прича о 170 година хемије у Србији и Хемијском факултету Универзитета у Београду. in Хемијски преглед
Београд : Српско хемијско друштво.(65), 41-44.
https://hdl.handle.net/21.15107/rcub_cherry_6567

Милановић Маштраповић ВД, Савић СД, Софренић ИВ. Кратка прича о 170 година хемије у Србији и Хемијском факултету Универзитета у Београду. in Хемијски преглед. 2024;(65):41-44.
https://hdl.handle.net/21.15107/rcub_cherry_6567 .

Милановић Маштраповић, Весна Д., Савић, Слађана Д., Софренић, Ивана В., "Кратка прича о 170 година хемије у Србији и Хемијском факултету Универзитета у Београду" in Хемијски преглед, no. 65 (2024):41-44,
https://hdl.handle.net/21.15107/rcub_cherry_6567 .

TY  - GEN
AU  - Шишаковић, Исидора
AU  - Мирковић, Ања
AU  - Радовановић, Мина
AU  - Крмпота, Ивана
AU  - Савић, Слађана
AU  - Тинтор, Ђорђо
AU  - Шкиљевић, Романа
PY  - 2024
UR  - http://chem.bg.ac.rs/studorg/
UR  - https://www.facebook.com/pozitroncasopis/
UR  - https://www.instagram.com/pozitroncasopis/
UR  - pozitron@chem.bg.ac.rs
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6652
AB  - Овај број отварамо текстом о фотобиореакторима, а у тексту који га прати се упознајемо са хемијом која стоји иза успешности злочина описаних у романима Агате Кристи. Завирите у чудесни свет нековалентних интеракција и сазнајте више о Интернационалној конференцији о нековалентним интеракција у тексту Ђорђа Тинтора, студента завршне године студија Биохемије. Разговарамо са др Џефом Фокатном, професором и продакеном за истраживања Природно-математичког факултета у Белгији који је познат као краљ GCxGC-MS анализе. Мастер студенткиња Романа Шкиљевић нам представља стартап свет кроз текст о ,,Стартап викенду“ одржаном у мају ове године у Новом Саду. У овом броју вам представљамо и пројекат MET-EFFECT којим руководи др Љиљана Михајловић Лалић, а бави се третманом канцера и заштитом животне средине помоћу комплекса прелазних метала. Као и увек, очекује вас текст о алумнистима Хемијског факултета, а овај пут је то Марија Неимаревић, наставница хемије и примењених наука у Петој београдској гимназији. На самом крају броја, пронађите информације о актуелним вестима из хемије и студентског живота на Хемијском факултету у Ретросинтези и развеселите се уз Позитиву. Уживајте!
PB  - Универзитет у Београду – Хемијски факултет
T1  - Позитрон - 34
VL  - 34
SP  - 1
EP  - 31
ER  - 

@misc{
author = "Шишаковић, Исидора and Мирковић, Ања and Радовановић, Мина and Крмпота, Ивана and Савић, Слађана and Тинтор, Ђорђо and Шкиљевић, Романа",
year = "2024",
abstract = "Овај број отварамо текстом о фотобиореакторима, а у тексту који га прати се упознајемо са хемијом која стоји иза успешности злочина описаних у романима Агате Кристи. Завирите у чудесни свет нековалентних интеракција и сазнајте више о Интернационалној конференцији о нековалентним интеракција у тексту Ђорђа Тинтора, студента завршне године студија Биохемије. Разговарамо са др Џефом Фокатном, професором и продакеном за истраживања Природно-математичког факултета у Белгији који је познат као краљ GCxGC-MS анализе. Мастер студенткиња Романа Шкиљевић нам представља стартап свет кроз текст о ,,Стартап викенду“ одржаном у мају ове године у Новом Саду. У овом броју вам представљамо и пројекат MET-EFFECT којим руководи др Љиљана Михајловић Лалић, а бави се третманом канцера и заштитом животне средине помоћу комплекса прелазних метала. Као и увек, очекује вас текст о алумнистима Хемијског факултета, а овај пут је то Марија Неимаревић, наставница хемије и примењених наука у Петој београдској гимназији. На самом крају броја, пронађите информације о актуелним вестима из хемије и студентског живота на Хемијском факултету у Ретросинтези и развеселите се уз Позитиву. Уживајте!",
publisher = "Универзитет у Београду – Хемијски факултет",
title = "Позитрон - 34",
volume = "34",
pages = "1-31"
}

Шишаковић, И., Мирковић, А., Радовановић, М., Крмпота, И., Савић, С., Тинтор, Ђ.,& Шкиљевић, Р.. (2024). Позитрон - 34. 
Универзитет у Београду – Хемијски факултет., 34, 1-31.

Шишаковић И, Мирковић А, Радовановић М, Крмпота И, Савић С, Тинтор Ђ, Шкиљевић Р. Позитрон - 34. 2024;34:1-31..

Шишаковић, Исидора, Мирковић, Ања, Радовановић, Мина, Крмпота, Ивана, Савић, Слађана, Тинтор, Ђорђо, Шкиљевић, Романа, "Позитрон - 34", 34 (2024):1-31.

TY  - JOUR
AU  - Jednak Berić, Tanja
AU  - Vrvić, Miroslav
AU  - Lješević, Marija
AU  - Avdalović, Jelena
AU  - Ilić, Mila
AU  - Crnković, Dragan
AU  - Jovančićević, Branimir
AU  - Miletić, Srđan
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6604
AB  - Environmental contextMitigating the environmental fallout of industrial accidents is crucial. In a recent study, researchers conducted tests on model substrates to explore the effectiveness of bioremediation in treating complex refinery contaminants resulting from both accidental and deliberate facility damage. The research reveals that bioremediation can be a promising, eco-friendly solution for cleaning up such pollutants, aligning with broader efforts to combat environmental harm resulting from industrial incidents.RationaleBioremediation harnesses microorganisms’ diverse metabolic abilities to detoxify and eliminate pollutants, particularly hydrocarbon-based ones such as oil. This natural biodegradation process performed by microorganisms is a cost-effective method for environmental cleanup compared to other remediation technologies.MethodologyIn this study, we examined the fate of heavy metals, cobalt and molybdenum, by the analysis of the basic chemical parameters of other sample components, such as n-hexane extractable substances and total petroleum hydrocarbons. The metal content was determined using inductively coupled plasma–optical emission spectrometry (ICP-OES). Exchangeable (loosely bound to the surface of particles and due to its high mobility and availability is crucial for understanding the potential immediate impact of metal contamination) and more stable fractions of the metal and the metal forms were determined using a sequential extraction method. The phase composition of the samples was determined by X-ray diffraction.ResultsIn our microbiological analysis, we isolated various cultures from a consortium of microorganisms. Basic chemical analysis indicators, such as n-hexane extractable substances, total petroleum hydrocarbons and humic acids, reflected robust microbiological activity. During the study, metals in exchangeable form decreased and those in more stable forms increased.DiscussionThe sequential extraction of cobalt and molybdenum revealed shifts in various metal fractions within the bioaugmented substrate post-bioremediation, differing from the initial substrate. These alterations in metal fractions are likely attributable to microbial actions, leading to the formation of more stable metal fractions throughout the bioremediation process.
PB  - CSIRO Publishing
T2  - Environmental Chemistry
T1  - Supplementary material for the article: T. Jednak Berić, M. M. Vrvić, M. Lješević, J. Avdalović, M. Ilić, D. Crnković, B. Jovančićević, S. Miletić; Testing of the bioremediation on model substrates for complex refinery contaminants arising from accidental or deliberate facility damage. Environmental Chemistry 21 (2024) EN23111. https://doi.org/10.1071/EN23111
VL  - 21
IS  - 5
SP  - EN23111
DO  - 10.1071/EN23111
ER  - 

@article{
author = "Jednak Berić, Tanja and Vrvić, Miroslav and Lješević, Marija and Avdalović, Jelena and Ilić, Mila and Crnković, Dragan and Jovančićević, Branimir and Miletić, Srđan",
year = "2024",
abstract = "Environmental contextMitigating the environmental fallout of industrial accidents is crucial. In a recent study, researchers conducted tests on model substrates to explore the effectiveness of bioremediation in treating complex refinery contaminants resulting from both accidental and deliberate facility damage. The research reveals that bioremediation can be a promising, eco-friendly solution for cleaning up such pollutants, aligning with broader efforts to combat environmental harm resulting from industrial incidents.RationaleBioremediation harnesses microorganisms’ diverse metabolic abilities to detoxify and eliminate pollutants, particularly hydrocarbon-based ones such as oil. This natural biodegradation process performed by microorganisms is a cost-effective method for environmental cleanup compared to other remediation technologies.MethodologyIn this study, we examined the fate of heavy metals, cobalt and molybdenum, by the analysis of the basic chemical parameters of other sample components, such as n-hexane extractable substances and total petroleum hydrocarbons. The metal content was determined using inductively coupled plasma–optical emission spectrometry (ICP-OES). Exchangeable (loosely bound to the surface of particles and due to its high mobility and availability is crucial for understanding the potential immediate impact of metal contamination) and more stable fractions of the metal and the metal forms were determined using a sequential extraction method. The phase composition of the samples was determined by X-ray diffraction.ResultsIn our microbiological analysis, we isolated various cultures from a consortium of microorganisms. Basic chemical analysis indicators, such as n-hexane extractable substances, total petroleum hydrocarbons and humic acids, reflected robust microbiological activity. During the study, metals in exchangeable form decreased and those in more stable forms increased.DiscussionThe sequential extraction of cobalt and molybdenum revealed shifts in various metal fractions within the bioaugmented substrate post-bioremediation, differing from the initial substrate. These alterations in metal fractions are likely attributable to microbial actions, leading to the formation of more stable metal fractions throughout the bioremediation process.",
publisher = "CSIRO Publishing",
journal = "Environmental Chemistry",
title = "Supplementary material for the article: T. Jednak Berić, M. M. Vrvić, M. Lješević, J. Avdalović, M. Ilić, D. Crnković, B. Jovančićević, S. Miletić; Testing of the bioremediation on model substrates for complex refinery contaminants arising from accidental or deliberate facility damage. Environmental Chemistry 21 (2024) EN23111. https://doi.org/10.1071/EN23111",
volume = "21",
number = "5",
pages = "EN23111",
doi = "10.1071/EN23111"
}

Jednak Berić, T., Vrvić, M., Lješević, M., Avdalović, J., Ilić, M., Crnković, D., Jovančićević, B.,& Miletić, S.. (2024). Supplementary material for the article: T. Jednak Berić, M. M. Vrvić, M. Lješević, J. Avdalović, M. Ilić, D. Crnković, B. Jovančićević, S. Miletić; Testing of the bioremediation on model substrates for complex refinery contaminants arising from accidental or deliberate facility damage. Environmental Chemistry 21 (2024) EN23111. https://doi.org/10.1071/EN23111. in Environmental Chemistry
CSIRO Publishing., 21(5), EN23111.
https://doi.org/10.1071/EN23111

Jednak Berić T, Vrvić M, Lješević M, Avdalović J, Ilić M, Crnković D, Jovančićević B, Miletić S. Supplementary material for the article: T. Jednak Berić, M. M. Vrvić, M. Lješević, J. Avdalović, M. Ilić, D. Crnković, B. Jovančićević, S. Miletić; Testing of the bioremediation on model substrates for complex refinery contaminants arising from accidental or deliberate facility damage. Environmental Chemistry 21 (2024) EN23111. https://doi.org/10.1071/EN23111. in Environmental Chemistry. 2024;21(5):EN23111.
doi:10.1071/EN23111 .

Jednak Berić, Tanja, Vrvić, Miroslav, Lješević, Marija, Avdalović, Jelena, Ilić, Mila, Crnković, Dragan, Jovančićević, Branimir, Miletić, Srđan, "Supplementary material for the article: T. Jednak Berić, M. M. Vrvić, M. Lješević, J. Avdalović, M. Ilić, D. Crnković, B. Jovančićević, S. Miletić; Testing of the bioremediation on model substrates for complex refinery contaminants arising from accidental or deliberate facility damage. Environmental Chemistry 21 (2024) EN23111. https://doi.org/10.1071/EN23111" in Environmental Chemistry, 21, no. 5 (2024):EN23111,
https://doi.org/10.1071/EN23111 . .

TY  - JOUR
AU  - Ivković, Đurđa
AU  - Cvijetić, Ilija
AU  - Radoičić, Aleksandra
AU  - Stojković-Filipović, Jelena
AU  - Trifković, Jelena
AU  - Krstić Ristivojević, Maja
AU  - Ristivojević, Petar
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6561
AB  - As a functional extraction medium, natural deep eutectic solvents (NADESs) can dissolve various plant metabolites. Those solvents provide untapped potential for creating novel green extracts with distinctive phytochemical signatures and unique biological activities. This is particularly relevant given the rising need for eco-friendly and sustainable skin care products. The main aim of this work was to optimize the most efficient natural deep eutectic solvents (NADESs) for extracting bioactives from 18 medicinal herbs applicable to the cosmetic industry. Selection of the most potent herbs involved assessing their conventional extracts for tyrosinase inhibition, antioxidant activity, and keratinocyte cytotoxicity. Moreover, we analyzed the phenolic profile using ultra-high-pressure liquid chromatography/mass spectrometry (UHPLC/MS) and spectrophotometric assays such as total phenolic (TPC) and flavonoid content (TFC). Using the COSMO-RS method, we modeled the solubility of 12 phenolics in 64 virtual NADESs and selected the 7 most promising ones for further experimental validation. NADESs, including betaine-urea, betaine-proline, and betaine-lysine, were computationally chosen and demonstrated the highest levels of TPC and antioxidative capacity, as confirmed by in vitro assays. The proposed combination of NADES herbal extracts represents a promising natural constituent for the cosmetic industry.
T2  - Processes
T1  - NADES-Based Extracts of Selected Medicinal Herbs as Promising Formulations for Cosmetic Usage
VL  - 12
IS  - 5
SP  - 992
DO  - 10.3390/pr12050992
ER  - 

@article{
author = "Ivković, Đurđa and Cvijetić, Ilija and Radoičić, Aleksandra and Stojković-Filipović, Jelena and Trifković, Jelena and Krstić Ristivojević, Maja and Ristivojević, Petar",
year = "2024",
abstract = "As a functional extraction medium, natural deep eutectic solvents (NADESs) can dissolve various plant metabolites. Those solvents provide untapped potential for creating novel green extracts with distinctive phytochemical signatures and unique biological activities. This is particularly relevant given the rising need for eco-friendly and sustainable skin care products. The main aim of this work was to optimize the most efficient natural deep eutectic solvents (NADESs) for extracting bioactives from 18 medicinal herbs applicable to the cosmetic industry. Selection of the most potent herbs involved assessing their conventional extracts for tyrosinase inhibition, antioxidant activity, and keratinocyte cytotoxicity. Moreover, we analyzed the phenolic profile using ultra-high-pressure liquid chromatography/mass spectrometry (UHPLC/MS) and spectrophotometric assays such as total phenolic (TPC) and flavonoid content (TFC). Using the COSMO-RS method, we modeled the solubility of 12 phenolics in 64 virtual NADESs and selected the 7 most promising ones for further experimental validation. NADESs, including betaine-urea, betaine-proline, and betaine-lysine, were computationally chosen and demonstrated the highest levels of TPC and antioxidative capacity, as confirmed by in vitro assays. The proposed combination of NADES herbal extracts represents a promising natural constituent for the cosmetic industry.",
journal = "Processes",
title = "NADES-Based Extracts of Selected Medicinal Herbs as Promising Formulations for Cosmetic Usage",
volume = "12",
number = "5",
pages = "992",
doi = "10.3390/pr12050992"
}

Ivković, Đ., Cvijetić, I., Radoičić, A., Stojković-Filipović, J., Trifković, J., Krstić Ristivojević, M.,& Ristivojević, P.. (2024). NADES-Based Extracts of Selected Medicinal Herbs as Promising Formulations for Cosmetic Usage. in Processes, 12(5), 992.
https://doi.org/10.3390/pr12050992

Ivković Đ, Cvijetić I, Radoičić A, Stojković-Filipović J, Trifković J, Krstić Ristivojević M, Ristivojević P. NADES-Based Extracts of Selected Medicinal Herbs as Promising Formulations for Cosmetic Usage. in Processes. 2024;12(5):992.
doi:10.3390/pr12050992 .

Ivković, Đurđa, Cvijetić, Ilija, Radoičić, Aleksandra, Stojković-Filipović, Jelena, Trifković, Jelena, Krstić Ristivojević, Maja, Ristivojević, Petar, "NADES-Based Extracts of Selected Medicinal Herbs as Promising Formulations for Cosmetic Usage" in Processes, 12, no. 5 (2024):992,
https://doi.org/10.3390/pr12050992 . .

TY  - JOUR
AU  - Petrović, Tamara
AU  - Gligorijević, Nevenka
AU  - Medaković, Vesna
AU  - Veljković, Dušan
AU  - Aranđelović, Sandra
AU  - Grgurić-Šipka, Sanja
AU  - Poljarević, Jelena
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6609
AB  - Three oxorhenium(V) complexes [ReOLCl2(PPh3)] (C1–C3) were synthesized in the reaction of 2,3-pyridinedicarboxylic acid (HL1), 2,5-pyridinedicarboxylic acid (HL2), and 2,6-pyridinedicarboxylic acid (HL3) with [ReOCl3(PPh3)2]. Chemical structures of synthesized compounds were confirmed using standard analytical techniques. The most stable geometry of complexes was proposed using density functional theory calculations. The antiproliferative activity of the synthesized complexes was evaluated in a panel of human tumor cell lines (A549, PANC-1, OVCAR-3, and MDA-MB-231) and in one nontumor cell line (MRC-5), in comparison with the activity of cisplatin as a reference drug. The complex C3 exhibited the highest antiproliferative potential in PANC-1 cells, with IC50 48.73 ± 0.31 μM. Our previous research of oxorhenium(V) complexes suggested the involvement of drug-efflux transporter P-glycoprotein (Pgp) in the detoxification of rhenium complexes in pancreatic adenocarcinoma cells. In the present study, the effect of verapamil hydrochloride, the specific pharmacological blocker of Pgp, was tested in combination with novel rhenium complexes C1–C3 or cisplatin (CDDP), in PANC-1 cells. The verapamil enhanced the antiproliferative activity of complex C3, indicating again the role of Pgp in detoxification of oxorhenium(V) complexes in highly invasive and resistant PANC-1 cells.
PB  - Wiley
T2  - Applied Organometallic Chemistry
T1  - Oxorhenium(V) complexes with pyridinedicarboxylic  ligands: Synthesis, density functional theory calculations,  and drug combination study
VL  - 38
SP  - e7623
DO  - 10.1002/aoc.7623
ER  - 

@article{
author = "Petrović, Tamara and Gligorijević, Nevenka and Medaković, Vesna and Veljković, Dušan and Aranđelović, Sandra and Grgurić-Šipka, Sanja and Poljarević, Jelena",
year = "2024",
abstract = "Three oxorhenium(V) complexes [ReOLCl2(PPh3)] (C1–C3) were synthesized in the reaction of 2,3-pyridinedicarboxylic acid (HL1), 2,5-pyridinedicarboxylic acid (HL2), and 2,6-pyridinedicarboxylic acid (HL3) with [ReOCl3(PPh3)2]. Chemical structures of synthesized compounds were confirmed using standard analytical techniques. The most stable geometry of complexes was proposed using density functional theory calculations. The antiproliferative activity of the synthesized complexes was evaluated in a panel of human tumor cell lines (A549, PANC-1, OVCAR-3, and MDA-MB-231) and in one nontumor cell line (MRC-5), in comparison with the activity of cisplatin as a reference drug. The complex C3 exhibited the highest antiproliferative potential in PANC-1 cells, with IC50 48.73 ± 0.31 μM. Our previous research of oxorhenium(V) complexes suggested the involvement of drug-efflux transporter P-glycoprotein (Pgp) in the detoxification of rhenium complexes in pancreatic adenocarcinoma cells. In the present study, the effect of verapamil hydrochloride, the specific pharmacological blocker of Pgp, was tested in combination with novel rhenium complexes C1–C3 or cisplatin (CDDP), in PANC-1 cells. The verapamil enhanced the antiproliferative activity of complex C3, indicating again the role of Pgp in detoxification of oxorhenium(V) complexes in highly invasive and resistant PANC-1 cells.",
publisher = "Wiley",
journal = "Applied Organometallic Chemistry",
title = "Oxorhenium(V) complexes with pyridinedicarboxylic  ligands: Synthesis, density functional theory calculations,  and drug combination study",
volume = "38",
pages = "e7623",
doi = "10.1002/aoc.7623"
}

Petrović, T., Gligorijević, N., Medaković, V., Veljković, D., Aranđelović, S., Grgurić-Šipka, S.,& Poljarević, J.. (2024). Oxorhenium(V) complexes with pyridinedicarboxylic  ligands: Synthesis, density functional theory calculations,  and drug combination study. in Applied Organometallic Chemistry
Wiley., 38, e7623.
https://doi.org/10.1002/aoc.7623

Petrović T, Gligorijević N, Medaković V, Veljković D, Aranđelović S, Grgurić-Šipka S, Poljarević J. Oxorhenium(V) complexes with pyridinedicarboxylic  ligands: Synthesis, density functional theory calculations,  and drug combination study. in Applied Organometallic Chemistry. 2024;38:e7623.
doi:10.1002/aoc.7623 .

Petrović, Tamara, Gligorijević, Nevenka, Medaković, Vesna, Veljković, Dušan, Aranđelović, Sandra, Grgurić-Šipka, Sanja, Poljarević, Jelena, "Oxorhenium(V) complexes with pyridinedicarboxylic  ligands: Synthesis, density functional theory calculations,  and drug combination study" in Applied Organometallic Chemistry, 38 (2024):e7623,
https://doi.org/10.1002/aoc.7623 . .

TY  - JOUR
AU  - Minić, Simeon
AU  - Veličković, Luka
AU  - Annighöfer, Burkhard
AU  - Thureau, Aurélien
AU  - Gligorijević, Nikola
AU  - Jovanović, Zorana
AU  - Brûlet, Annie
AU  - Combet, Sophie
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6595
AB  - The red macroalgae Porphyra, commonly known as Nori, is widely used as food around the world due to its high nutrient content, including the significant abundance of colored phycobiliproteins (PBPs). Among these, R-phycocyanin (R-PC) stands out for its vibrant purple color and numerous bioactive properties, making it a valuable protein for the food industry. However, R-PC's limited thermal stability necessitates alternative processing methods to preserve its color and bioactive properties. Our study aimed to investigate the in-situ stability of oligomeric R-PC under high pressure (HP) conditions (up to 4000 bar) using a combination of absorption, fluorescence, and small-angle X-ray scattering (SAXS) techniques. The unfolding of R-PC is a multiphase process. Initially, low pressure induces conformational changes in the R-PC oligomeric form (trimers). As pressure increases above 1600 bar, these trimers dissociate into monomers, and at pressures above 3000 bar, the subunits begin to unfold. When returned to atmospheric pressure, R-PC partially refolds, retaining 50% of its original color absorbance. In contrast, heat treatment causes irreversible and detrimental effects on R-PC color, highlighting the advantages of HP treatment in preserving both the color and bioactive properties of R-PC compared to heat treatment.
PB  - Wiley
T2  - Protein Science
T1  - Probing the structural stability of R-phycocyanin under pressure
VL  - 33
IS  - 9
SP  - e5145
DO  - 10.1002/pro.5145
ER  - 

@article{
author = "Minić, Simeon and Veličković, Luka and Annighöfer, Burkhard and Thureau, Aurélien and Gligorijević, Nikola and Jovanović, Zorana and Brûlet, Annie and Combet, Sophie",
year = "2024",
abstract = "The red macroalgae Porphyra, commonly known as Nori, is widely used as food around the world due to its high nutrient content, including the significant abundance of colored phycobiliproteins (PBPs). Among these, R-phycocyanin (R-PC) stands out for its vibrant purple color and numerous bioactive properties, making it a valuable protein for the food industry. However, R-PC's limited thermal stability necessitates alternative processing methods to preserve its color and bioactive properties. Our study aimed to investigate the in-situ stability of oligomeric R-PC under high pressure (HP) conditions (up to 4000 bar) using a combination of absorption, fluorescence, and small-angle X-ray scattering (SAXS) techniques. The unfolding of R-PC is a multiphase process. Initially, low pressure induces conformational changes in the R-PC oligomeric form (trimers). As pressure increases above 1600 bar, these trimers dissociate into monomers, and at pressures above 3000 bar, the subunits begin to unfold. When returned to atmospheric pressure, R-PC partially refolds, retaining 50% of its original color absorbance. In contrast, heat treatment causes irreversible and detrimental effects on R-PC color, highlighting the advantages of HP treatment in preserving both the color and bioactive properties of R-PC compared to heat treatment.",
publisher = "Wiley",
journal = "Protein Science",
title = "Probing the structural stability of R-phycocyanin under pressure",
volume = "33",
number = "9",
pages = "e5145",
doi = "10.1002/pro.5145"
}

Minić, S., Veličković, L., Annighöfer, B., Thureau, A., Gligorijević, N., Jovanović, Z., Brûlet, A.,& Combet, S.. (2024). Probing the structural stability of R-phycocyanin under pressure. in Protein Science
Wiley., 33(9), e5145.
https://doi.org/10.1002/pro.5145

Minić S, Veličković L, Annighöfer B, Thureau A, Gligorijević N, Jovanović Z, Brûlet A, Combet S. Probing the structural stability of R-phycocyanin under pressure. in Protein Science. 2024;33(9):e5145.
doi:10.1002/pro.5145 .

Minić, Simeon, Veličković, Luka, Annighöfer, Burkhard, Thureau, Aurélien, Gligorijević, Nikola, Jovanović, Zorana, Brûlet, Annie, Combet, Sophie, "Probing the structural stability of R-phycocyanin under pressure" in Protein Science, 33, no. 9 (2024):e5145,
https://doi.org/10.1002/pro.5145 . .

TY  - JOUR
AU  - Jovanović, Vesna B.
AU  - Nikolić, Milan
AU  - Stojanović, Srđan Đ.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6607
AB  - In this in silico study, it was investigated whether phycobilins
(phycocyanobilin, phycoerythrobilin and phycourobilin) could be inhibitors of
the activity of the main proteins of the SARS-CoV-2 virus. All chromophores
exhibited a binding energy value of ≥–37 kJ mol-1 for PLpro-WT, PLpro-
-C111S, helicase-ANP binding site, Nsp3-macrodomain, Nsp3-MES site and
Nsp10/14-N7-Mtase. Phycocyanobilin showed the highest binding energy of
–44.77 kJ mol-1 against the target protein PLpro-C111S. It was found that,
apart from the hydrogen bonds and hydrophobic interactions, phycobilins also
form electrostatic interactions with the SARS-CoV-2 proteins. The network of
non-covalent interactions was found to be important for the stability of the
examined virus proteins. All phycobilins have good pharmacokinetic and drug-
-likeness properties. This study’s results suggest that the screened phycobilins
could serve as promising drugs for the treatment of COVID-19 with further
rigorous validation studies.
PB  - Belgrade : Serbian Chemical Society
T2  - Jornal of Serbian Chemical Society
T1  - In silico studies of phycobilins as potential candidates for inhibitors of viral proteins associated with COVID-19
VL  - 89
IS  - 7-8
SP  - 997
EP  - 1009
DO  - 10.2298/JSC240326052J
ER  - 

@article{
author = "Jovanović, Vesna B. and Nikolić, Milan and Stojanović, Srđan Đ.",
year = "2024",
abstract = "In this in silico study, it was investigated whether phycobilins
(phycocyanobilin, phycoerythrobilin and phycourobilin) could be inhibitors of
the activity of the main proteins of the SARS-CoV-2 virus. All chromophores
exhibited a binding energy value of ≥–37 kJ mol-1 for PLpro-WT, PLpro-
-C111S, helicase-ANP binding site, Nsp3-macrodomain, Nsp3-MES site and
Nsp10/14-N7-Mtase. Phycocyanobilin showed the highest binding energy of
–44.77 kJ mol-1 against the target protein PLpro-C111S. It was found that,
apart from the hydrogen bonds and hydrophobic interactions, phycobilins also
form electrostatic interactions with the SARS-CoV-2 proteins. The network of
non-covalent interactions was found to be important for the stability of the
examined virus proteins. All phycobilins have good pharmacokinetic and drug-
-likeness properties. This study’s results suggest that the screened phycobilins
could serve as promising drugs for the treatment of COVID-19 with further
rigorous validation studies.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Jornal of Serbian Chemical Society",
title = "In silico studies of phycobilins as potential candidates for inhibitors of viral proteins associated with COVID-19",
volume = "89",
number = "7-8",
pages = "997-1009",
doi = "10.2298/JSC240326052J"
}

Jovanović, V. B., Nikolić, M.,& Stojanović, S. Đ.. (2024). In silico studies of phycobilins as potential candidates for inhibitors of viral proteins associated with COVID-19. in Jornal of Serbian Chemical Society
Belgrade : Serbian Chemical Society., 89(7-8), 997-1009.
https://doi.org/10.2298/JSC240326052J

Jovanović VB, Nikolić M, Stojanović SĐ. In silico studies of phycobilins as potential candidates for inhibitors of viral proteins associated with COVID-19. in Jornal of Serbian Chemical Society. 2024;89(7-8):997-1009.
doi:10.2298/JSC240326052J .

Jovanović, Vesna B., Nikolić, Milan, Stojanović, Srđan Đ., "In silico studies of phycobilins as potential candidates for inhibitors of viral proteins associated with COVID-19" in Jornal of Serbian Chemical Society, 89, no. 7-8 (2024):997-1009,
https://doi.org/10.2298/JSC240326052J . .

TY  - JOUR
AU  - Jakovljević, Danijel
AU  - Nikolić, Milan
AU  - Jovanović, Vesna B.
AU  - Vidonja Uzelac, Teodora
AU  - Nikolić-Kokić, Aleksandra
AU  - Novaković, Emilija
AU  - Miljević, Čedo
AU  - Milovanović, Maja
AU  - Blagojević, Duško
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6574
AB  - Background: Epilepsy is a chronic brain disease affecting millions of people worldwide,
but little is known about the impact of anti-seizure medications on redox homeostasis. Methods:
This study aimed to compare the effects of the long-term use of oral anti-seizure medications in
monotherapy (lamotrigine, carbamazepine, and valproate) on antioxidant enzymes: superoxide dismutase,
catalase, glutathione peroxidase, glutathione reductase, haemoglobin, and methaemoglobin
content in erythrocytes, and concentrations of total proteins and thiols, nitrites, lipid peroxides and
total glutathione in the plasma of epilepsy patients and drug-naïve patients. Results: The results
showed that lamotrigine therapy led to lower superoxide dismutase activity (p < 0.005) and lower
concentrations of total thiols (p < 0.01) and lipid peroxides (p < 0.01) compared to controls. On the
other hand, therapy with carbamazepine increased nitrite levels (p < 0.01) but reduced superoxide
dismutase activity (p < 0.005). In the valproate group, only a decrease in catalase activity was observed
(p < 0.005). Canonical discriminant analysis showed that the composition of antioxidant enzymes in
erythrocytes was different for both the lamotrigine and carbamazepine groups, while the controls
were separated from all others. Conclusions: Monotherapy with anti-seizure medications discretely
alters redox homeostasis, followed by distinct relationships between antioxidant components.
PB  - MDPI
T2  - Pharmaceuticals
T1  - Influence of Long-Term Anti-Seizure Medications on Redox Parameters in Human Blood
VL  - 17
IS  - 1
SP  - 130
DO  - 10.3390/ph17010130
ER  - 

@article{
author = "Jakovljević, Danijel and Nikolić, Milan and Jovanović, Vesna B. and Vidonja Uzelac, Teodora and Nikolić-Kokić, Aleksandra and Novaković, Emilija and Miljević, Čedo and Milovanović, Maja and Blagojević, Duško",
year = "2024",
abstract = "Background: Epilepsy is a chronic brain disease affecting millions of people worldwide,
but little is known about the impact of anti-seizure medications on redox homeostasis. Methods:
This study aimed to compare the effects of the long-term use of oral anti-seizure medications in
monotherapy (lamotrigine, carbamazepine, and valproate) on antioxidant enzymes: superoxide dismutase,
catalase, glutathione peroxidase, glutathione reductase, haemoglobin, and methaemoglobin
content in erythrocytes, and concentrations of total proteins and thiols, nitrites, lipid peroxides and
total glutathione in the plasma of epilepsy patients and drug-naïve patients. Results: The results
showed that lamotrigine therapy led to lower superoxide dismutase activity (p < 0.005) and lower
concentrations of total thiols (p < 0.01) and lipid peroxides (p < 0.01) compared to controls. On the
other hand, therapy with carbamazepine increased nitrite levels (p < 0.01) but reduced superoxide
dismutase activity (p < 0.005). In the valproate group, only a decrease in catalase activity was observed
(p < 0.005). Canonical discriminant analysis showed that the composition of antioxidant enzymes in
erythrocytes was different for both the lamotrigine and carbamazepine groups, while the controls
were separated from all others. Conclusions: Monotherapy with anti-seizure medications discretely
alters redox homeostasis, followed by distinct relationships between antioxidant components.",
publisher = "MDPI",
journal = "Pharmaceuticals",
title = "Influence of Long-Term Anti-Seizure Medications on Redox Parameters in Human Blood",
volume = "17",
number = "1",
pages = "130",
doi = "10.3390/ph17010130"
}

Jakovljević, D., Nikolić, M., Jovanović, V. B., Vidonja Uzelac, T., Nikolić-Kokić, A., Novaković, E., Miljević, Č., Milovanović, M.,& Blagojević, D.. (2024). Influence of Long-Term Anti-Seizure Medications on Redox Parameters in Human Blood. in Pharmaceuticals
MDPI., 17(1), 130.
https://doi.org/10.3390/ph17010130

Jakovljević D, Nikolić M, Jovanović VB, Vidonja Uzelac T, Nikolić-Kokić A, Novaković E, Miljević Č, Milovanović M, Blagojević D. Influence of Long-Term Anti-Seizure Medications on Redox Parameters in Human Blood. in Pharmaceuticals. 2024;17(1):130.
doi:10.3390/ph17010130 .

Jakovljević, Danijel, Nikolić, Milan, Jovanović, Vesna B., Vidonja Uzelac, Teodora, Nikolić-Kokić, Aleksandra, Novaković, Emilija, Miljević, Čedo, Milovanović, Maja, Blagojević, Duško, "Influence of Long-Term Anti-Seizure Medications on Redox Parameters in Human Blood" in Pharmaceuticals, 17, no. 1 (2024):130,
https://doi.org/10.3390/ph17010130 . .

TY  - JOUR
AU  - Takić, Marija
AU  - Ranković, Slavica
AU  - Girek, Zdenka
AU  - Pavlović, Suzana
AU  - Jovanović, Petar
AU  - Jovanović, Vesna B.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6573
AB  - The plant-derived α-linolenic acid (ALA) is an essential n-3 acid highly susceptible to
oxidation, present in oils of flaxseeds, walnuts, canola, perilla, soy, and chia. After ingestion, it can
be incorporated in to body lipid pools (particularly triglycerides and phospholipid membranes),
and then endogenously metabolized through desaturation, elongation, and peroxisome oxidation
to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), with a very limited efficiency
(particularly for DHA), beta-oxidized as an energy source, or directly metabolized to C18-oxilipins.
At this moment, data in the literature about the effects of ALA supplementation on metabolic
syndrome (MetS) in humans are inconsistent, indicating no effects or some positive effects on all
MetS components (abdominal obesity, dyslipidemia, impaired insulin sensitivity and glucoregulation,
blood pressure, and liver steatosis). The major effects of ALA on MetS seem to be through its
conversion to more potent EPA and DHA, the impact on the n-3/n-6 ratio, and the consecutive effects
on the formation of oxylipins and endocannabinoids, inflammation, insulin sensitivity, and insulin
secretion, as well as adipocyte and hepatocytes function. It is important to distinguish the direct
effects of ALA from the effects of EPA and DHA metabolites. This review summarizes the most recent
findings on this topic and discusses the possible mechanisms.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome
VL  - 25
IS  - 9
SP  - 4909
DO  - 10.3390/ijms25094909
ER  - 

@article{
author = "Takić, Marija and Ranković, Slavica and Girek, Zdenka and Pavlović, Suzana and Jovanović, Petar and Jovanović, Vesna B.",
year = "2024",
abstract = "The plant-derived α-linolenic acid (ALA) is an essential n-3 acid highly susceptible to
oxidation, present in oils of flaxseeds, walnuts, canola, perilla, soy, and chia. After ingestion, it can
be incorporated in to body lipid pools (particularly triglycerides and phospholipid membranes),
and then endogenously metabolized through desaturation, elongation, and peroxisome oxidation
to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), with a very limited efficiency
(particularly for DHA), beta-oxidized as an energy source, or directly metabolized to C18-oxilipins.
At this moment, data in the literature about the effects of ALA supplementation on metabolic
syndrome (MetS) in humans are inconsistent, indicating no effects or some positive effects on all
MetS components (abdominal obesity, dyslipidemia, impaired insulin sensitivity and glucoregulation,
blood pressure, and liver steatosis). The major effects of ALA on MetS seem to be through its
conversion to more potent EPA and DHA, the impact on the n-3/n-6 ratio, and the consecutive effects
on the formation of oxylipins and endocannabinoids, inflammation, insulin sensitivity, and insulin
secretion, as well as adipocyte and hepatocytes function. It is important to distinguish the direct
effects of ALA from the effects of EPA and DHA metabolites. This review summarizes the most recent
findings on this topic and discusses the possible mechanisms.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome",
volume = "25",
number = "9",
pages = "4909",
doi = "10.3390/ijms25094909"
}

Takić, M., Ranković, S., Girek, Z., Pavlović, S., Jovanović, P.,& Jovanović, V. B.. (2024). Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome. in International Journal of Molecular Sciences
MDPI., 25(9), 4909.
https://doi.org/10.3390/ijms25094909

Takić M, Ranković S, Girek Z, Pavlović S, Jovanović P, Jovanović VB. Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome. in International Journal of Molecular Sciences. 2024;25(9):4909.
doi:10.3390/ijms25094909 .

Takić, Marija, Ranković, Slavica, Girek, Zdenka, Pavlović, Suzana, Jovanović, Petar, Jovanović, Vesna B., "Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome" in International Journal of Molecular Sciences, 25, no. 9 (2024):4909,
https://doi.org/10.3390/ijms25094909 . .

TY  - JOUR
AU  - Petrović, Tamara
AU  - Dimitrijević, Marija
AU  - Mihajlović-Lalić, Ljiljana
AU  - Stanković, Dalibor
AU  - Vlahović, Filip
AU  - Grgurić-Šipka, Sanja
AU  - Mihajilov-Krstev, Tatjana
AU  - Miladinović, Dragoljub
AU  - Poljarević, Jelena
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6569
AB  - Eight new ruthenium complexes (C1, C2 (Ru-benzene or Ru-toluene complexes with L1, 3amino-2-chloropyridine); C3, C4 (Ru-benzene or Ru-toluene complexes with L2, 2-amino-5chloropyridine); C5, C6 (Ru-benzene or Ru-toluene complexes with L3, 3-acetylpyridine); and C7, C8 (Ru-benzene or Ru-toluene complexes with L4, 4-acetylpyridine) were synthesized. The chemical structures and purity of synthesized compounds were confirmed using standard analytical methods such as 1H, 13C NMR and IR spectroscopy, mass spectrometry, and elemental analysis, and their electrochemical behavior was evaluated using cyclic voltammetry experiments. The stability of synthesized compounds in dimethyl sulfoxide solution was confirmed using 1H NMR spectroscopy. Finally, the antimicrobial potential of two complex precursors (CP1, [Ru(η6-benzene)Cl(μ-Cl)]2  and CP2, [Ru(η6-toluene)Cl(μ-Cl)]2), four ligands (L1 – L4), and eight corresponding complexes (C1 – C8) was screened against nine pathogenic microorganisms and two reference bacterial strains, using the micro-well dilution method. The highest antibacterial activity (0.63 mg/mL) exerted C5 against S. aureus, B. cereus, E. coli, and S. enteritidis, while complex C8 displayed more pronounced antimicrobial activity against C. albicans (MIC/MMC = 0.31 mg/mL). Subsequently, the studied complexes underwent a detailed examination utilizing the DFT methodology, acquiring important quantum-chemical descriptors. Notably, the HOMO-LUMO gap was established as a significant correlate with the antimicrobial activity of synthesized compounds.
PB  - Taylor & Francis
T2  - Journal of Coordination Chemistry
T1  - Synthesis and antimicrobial activity of new pyridine-based half-sandwich Ru(II) complexes
VL  - 77
IS  - 7-8
SP  - 750
EP  - 765
DO  - 10.1080/00958972.2024.2307911
ER  - 

@article{
author = "Petrović, Tamara and Dimitrijević, Marija and Mihajlović-Lalić, Ljiljana and Stanković, Dalibor and Vlahović, Filip and Grgurić-Šipka, Sanja and Mihajilov-Krstev, Tatjana and Miladinović, Dragoljub and Poljarević, Jelena",
year = "2024",
abstract = "Eight new ruthenium complexes (C1, C2 (Ru-benzene or Ru-toluene complexes with L1, 3amino-2-chloropyridine); C3, C4 (Ru-benzene or Ru-toluene complexes with L2, 2-amino-5chloropyridine); C5, C6 (Ru-benzene or Ru-toluene complexes with L3, 3-acetylpyridine); and C7, C8 (Ru-benzene or Ru-toluene complexes with L4, 4-acetylpyridine) were synthesized. The chemical structures and purity of synthesized compounds were confirmed using standard analytical methods such as 1H, 13C NMR and IR spectroscopy, mass spectrometry, and elemental analysis, and their electrochemical behavior was evaluated using cyclic voltammetry experiments. The stability of synthesized compounds in dimethyl sulfoxide solution was confirmed using 1H NMR spectroscopy. Finally, the antimicrobial potential of two complex precursors (CP1, [Ru(η6-benzene)Cl(μ-Cl)]2  and CP2, [Ru(η6-toluene)Cl(μ-Cl)]2), four ligands (L1 – L4), and eight corresponding complexes (C1 – C8) was screened against nine pathogenic microorganisms and two reference bacterial strains, using the micro-well dilution method. The highest antibacterial activity (0.63 mg/mL) exerted C5 against S. aureus, B. cereus, E. coli, and S. enteritidis, while complex C8 displayed more pronounced antimicrobial activity against C. albicans (MIC/MMC = 0.31 mg/mL). Subsequently, the studied complexes underwent a detailed examination utilizing the DFT methodology, acquiring important quantum-chemical descriptors. Notably, the HOMO-LUMO gap was established as a significant correlate with the antimicrobial activity of synthesized compounds.",
publisher = "Taylor & Francis",
journal = "Journal of Coordination Chemistry",
title = "Synthesis and antimicrobial activity of new pyridine-based half-sandwich Ru(II) complexes",
volume = "77",
number = "7-8",
pages = "750-765",
doi = "10.1080/00958972.2024.2307911"
}

Petrović, T., Dimitrijević, M., Mihajlović-Lalić, L., Stanković, D., Vlahović, F., Grgurić-Šipka, S., Mihajilov-Krstev, T., Miladinović, D.,& Poljarević, J.. (2024). Synthesis and antimicrobial activity of new pyridine-based half-sandwich Ru(II) complexes. in Journal of Coordination Chemistry
Taylor & Francis., 77(7-8), 750-765.
https://doi.org/10.1080/00958972.2024.2307911

Petrović T, Dimitrijević M, Mihajlović-Lalić L, Stanković D, Vlahović F, Grgurić-Šipka S, Mihajilov-Krstev T, Miladinović D, Poljarević J. Synthesis and antimicrobial activity of new pyridine-based half-sandwich Ru(II) complexes. in Journal of Coordination Chemistry. 2024;77(7-8):750-765.
doi:10.1080/00958972.2024.2307911 .

Petrović, Tamara, Dimitrijević, Marija, Mihajlović-Lalić, Ljiljana, Stanković, Dalibor, Vlahović, Filip, Grgurić-Šipka, Sanja, Mihajilov-Krstev, Tatjana, Miladinović, Dragoljub, Poljarević, Jelena, "Synthesis and antimicrobial activity of new pyridine-based half-sandwich Ru(II) complexes" in Journal of Coordination Chemistry, 77, no. 7-8 (2024):750-765,
https://doi.org/10.1080/00958972.2024.2307911 . .

TY  - JOUR
AU  - Mitić, Bojan
AU  - Jovanović, Vesna B.
AU  - Todosijević, Marina M.
AU  - Eckhard, Margret
AU  - Vasiljević, Ljubica
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6572
AB  - Chemical substances are of utmost importance for the biotic interactions between animals and their predators/
parasites; many of these semiochemicals are emitted for defence purposes. One of the most deterrent and toxic
biogenic substances we know of is hydrogen cyanide, which can be stored by certain insects, millipedes, centipedes
and arachnids in the form of stable and less volatile molecules. The aim of this study was to analyse the
biology and chemistry of such a defence mechanism in a geophilomorph centipede (Chilopoda). The cyanogenic
secretion of Clinopodes flavidus is discharged from the ventral glands, whose glandular units are located in the
space between the cuticle and the trunk muscles and do not extend deep into the segment. In addition to
hydrogen cyanide, the ventral secretion contains 2-methylpentanoic acid, benzaldehyde, benzoyl cyanide, 2-
methyl branched C-9 carboxylic acid (tentatively identified as 2-methyloctanoic acid), methyl 2-phenylacetate,
benzoic acid and mandelonitrile as well as four major proteins with a molecular weight of 150, 66.2, 59 and 55
kDa. The correlation between the presence of ventral glands and guarding with the female’s ventral side facing
away from the eggs and young indicates a functional link between these two traits. We hope that the specificity of
the chemical composition of the ventral secretion could serve as a criterion for chemotaxonomy and that the
analysis of more species will help to clarify the phylogenetic relationships within the Geophilomorpha.
PB  - Elsevier
T2  - Journal of Insect Physiology
T1  - Chemical defence of a centipede (Clinopodes flavidus)
VL  - 155
SP  - 104649
DO  - 10.1016/j.jinsphys.2024.104649
ER  - 

@article{
author = "Mitić, Bojan and Jovanović, Vesna B. and Todosijević, Marina M. and Eckhard, Margret and Vasiljević, Ljubica and Tešević, Vele and Vujisić, Ljubodrag",
year = "2024",
abstract = "Chemical substances are of utmost importance for the biotic interactions between animals and their predators/
parasites; many of these semiochemicals are emitted for defence purposes. One of the most deterrent and toxic
biogenic substances we know of is hydrogen cyanide, which can be stored by certain insects, millipedes, centipedes
and arachnids in the form of stable and less volatile molecules. The aim of this study was to analyse the
biology and chemistry of such a defence mechanism in a geophilomorph centipede (Chilopoda). The cyanogenic
secretion of Clinopodes flavidus is discharged from the ventral glands, whose glandular units are located in the
space between the cuticle and the trunk muscles and do not extend deep into the segment. In addition to
hydrogen cyanide, the ventral secretion contains 2-methylpentanoic acid, benzaldehyde, benzoyl cyanide, 2-
methyl branched C-9 carboxylic acid (tentatively identified as 2-methyloctanoic acid), methyl 2-phenylacetate,
benzoic acid and mandelonitrile as well as four major proteins with a molecular weight of 150, 66.2, 59 and 55
kDa. The correlation between the presence of ventral glands and guarding with the female’s ventral side facing
away from the eggs and young indicates a functional link between these two traits. We hope that the specificity of
the chemical composition of the ventral secretion could serve as a criterion for chemotaxonomy and that the
analysis of more species will help to clarify the phylogenetic relationships within the Geophilomorpha.",
publisher = "Elsevier",
journal = "Journal of Insect Physiology",
title = "Chemical defence of a centipede (Clinopodes flavidus)",
volume = "155",
pages = "104649",
doi = "10.1016/j.jinsphys.2024.104649"
}

Mitić, B., Jovanović, V. B., Todosijević, M. M., Eckhard, M., Vasiljević, L., Tešević, V.,& Vujisić, L.. (2024). Chemical defence of a centipede (Clinopodes flavidus). in Journal of Insect Physiology
Elsevier., 155, 104649.
https://doi.org/10.1016/j.jinsphys.2024.104649

Mitić B, Jovanović VB, Todosijević MM, Eckhard M, Vasiljević L, Tešević V, Vujisić L. Chemical defence of a centipede (Clinopodes flavidus). in Journal of Insect Physiology. 2024;155:104649.
doi:10.1016/j.jinsphys.2024.104649 .

Mitić, Bojan, Jovanović, Vesna B., Todosijević, Marina M., Eckhard, Margret, Vasiljević, Ljubica, Tešević, Vele, Vujisić, Ljubodrag, "Chemical defence of a centipede (Clinopodes flavidus)" in Journal of Insect Physiology, 155 (2024):104649,
https://doi.org/10.1016/j.jinsphys.2024.104649 . .

TY  - JOUR
AU  - Uzelac, Tamara
AU  - Takić, Marija
AU  - Stevanović, Vuk
AU  - Vidović, Nevena
AU  - Pantović, Ana
AU  - Jovanović, Petar
AU  - Jovanović, Vesna B.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6575
AB  - Intensive physical activity (PA) can lead to proteinuria and, consequently, serum protein
profiles in athletes. Therefore, the aim of this study was to investigate the effects of acute aronia juice
consumption before a simulated half-marathon race on serum protein profiles in recreational runners.
The pilot study was designed as a single-blind, placebo-controlled, crossover study, with 10
male participants who consumed aronia juice (containing 1.3 g polyphenols) or placebo before the
race. The blood levels of total proteins, albumin, the non-albumin fractions gamma, beta, alpha2
and alpha1, as well as renal function parameters, were determined before and 15 min, 1 h and 24 h
after the race. The significant changes in urea, creatinine and uric acid levels were noticed at selected
time points in both groups. In the placebo group, a significant decrease in total proteins (p < 0.05)
was observed 24 h after the race, along with an increase in gamma fraction abundance (p < 0.05). In
addition, urea and uric acid levels returned to baseline only in the aronia group 24 h after the race.
Thus, according to the results obtained, acute aronia juice supplementation before intensive PA
could influence the transient change in renal function and PA-induced protein loss in recreational
runners.
PB  - MDPI
T2  - Healthcare
T1  - The Potential Benefits of Acute Aronia Juice Supplementation on Physical Activity Induced Alterations of the Serum Protein Profiles in Recreational Runners: A Pilot Study
VL  - 12
SP  - 1276
DO  - 10.3390/healthcare12131276
ER  - 

@article{
author = "Uzelac, Tamara and Takić, Marija and Stevanović, Vuk and Vidović, Nevena and Pantović, Ana and Jovanović, Petar and Jovanović, Vesna B.",
year = "2024",
abstract = "Intensive physical activity (PA) can lead to proteinuria and, consequently, serum protein
profiles in athletes. Therefore, the aim of this study was to investigate the effects of acute aronia juice
consumption before a simulated half-marathon race on serum protein profiles in recreational runners.
The pilot study was designed as a single-blind, placebo-controlled, crossover study, with 10
male participants who consumed aronia juice (containing 1.3 g polyphenols) or placebo before the
race. The blood levels of total proteins, albumin, the non-albumin fractions gamma, beta, alpha2
and alpha1, as well as renal function parameters, were determined before and 15 min, 1 h and 24 h
after the race. The significant changes in urea, creatinine and uric acid levels were noticed at selected
time points in both groups. In the placebo group, a significant decrease in total proteins (p < 0.05)
was observed 24 h after the race, along with an increase in gamma fraction abundance (p < 0.05). In
addition, urea and uric acid levels returned to baseline only in the aronia group 24 h after the race.
Thus, according to the results obtained, acute aronia juice supplementation before intensive PA
could influence the transient change in renal function and PA-induced protein loss in recreational
runners.",
publisher = "MDPI",
journal = "Healthcare",
title = "The Potential Benefits of Acute Aronia Juice Supplementation on Physical Activity Induced Alterations of the Serum Protein Profiles in Recreational Runners: A Pilot Study",
volume = "12",
pages = "1276",
doi = "10.3390/healthcare12131276"
}

Uzelac, T., Takić, M., Stevanović, V., Vidović, N., Pantović, A., Jovanović, P.,& Jovanović, V. B.. (2024). The Potential Benefits of Acute Aronia Juice Supplementation on Physical Activity Induced Alterations of the Serum Protein Profiles in Recreational Runners: A Pilot Study. in Healthcare
MDPI., 12, 1276.
https://doi.org/10.3390/healthcare12131276

Uzelac T, Takić M, Stevanović V, Vidović N, Pantović A, Jovanović P, Jovanović VB. The Potential Benefits of Acute Aronia Juice Supplementation on Physical Activity Induced Alterations of the Serum Protein Profiles in Recreational Runners: A Pilot Study. in Healthcare. 2024;12:1276.
doi:10.3390/healthcare12131276 .

Uzelac, Tamara, Takić, Marija, Stevanović, Vuk, Vidović, Nevena, Pantović, Ana, Jovanović, Petar, Jovanović, Vesna B., "The Potential Benefits of Acute Aronia Juice Supplementation on Physical Activity Induced Alterations of the Serum Protein Profiles in Recreational Runners: A Pilot Study" in Healthcare, 12 (2024):1276,
https://doi.org/10.3390/healthcare12131276 . .

TY  - JOUR
AU  - Petrović, Tamara
AU  - Poljarević, Jelena
AU  - Nikolić, Stefan
AU  - Stojković-Filipović, Jelena
AU  - Mihajlović-Lalić, Ljiljana
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6646
AB  - The skin of newborns is classified as sensitive, with a higher risk of skin barrier disruption
and irritation of a diapered area. Despite dermatologist recommendations to use only water
and a cloth for cleaning, most of the population still relies on the comforts of modern
parenting, which includes intensive daily usage of baby wet wipes. Novel baby formulations
are designed following the concept of infant skin health, containing a gentle cleanser,
suitable emollient, and buffer system enabling a slightly acidic pH value and they are free
of ethyl alcohol. Thus, it is important to understand the chemical background of such a
complex liquid formulation, with emphasis on its safety. In line with this, the present paper
discusses the scientific background of various chemical compounds found in baby wipe
formulations to improve the understanding of wet wipe designs and direct them toward
more skin-friendly solutions.
PB  - Wiley
T2  - International Journal of Dermatology
T1  - A review of the key ingredients in industrial formulations of baby wet wipes
VL  - n/a
DO  - 10.1111/ijd.17351
ER  - 

@article{
author = "Petrović, Tamara and Poljarević, Jelena and Nikolić, Stefan and Stojković-Filipović, Jelena and Mihajlović-Lalić, Ljiljana",
year = "2024",
abstract = "The skin of newborns is classified as sensitive, with a higher risk of skin barrier disruption
and irritation of a diapered area. Despite dermatologist recommendations to use only water
and a cloth for cleaning, most of the population still relies on the comforts of modern
parenting, which includes intensive daily usage of baby wet wipes. Novel baby formulations
are designed following the concept of infant skin health, containing a gentle cleanser,
suitable emollient, and buffer system enabling a slightly acidic pH value and they are free
of ethyl alcohol. Thus, it is important to understand the chemical background of such a
complex liquid formulation, with emphasis on its safety. In line with this, the present paper
discusses the scientific background of various chemical compounds found in baby wipe
formulations to improve the understanding of wet wipe designs and direct them toward
more skin-friendly solutions.",
publisher = "Wiley",
journal = "International Journal of Dermatology",
title = "A review of the key ingredients in industrial formulations of baby wet wipes",
volume = "n/a",
doi = "10.1111/ijd.17351"
}

Petrović, T., Poljarević, J., Nikolić, S., Stojković-Filipović, J.,& Mihajlović-Lalić, L.. (2024). A review of the key ingredients in industrial formulations of baby wet wipes. in International Journal of Dermatology
Wiley., n/a.
https://doi.org/10.1111/ijd.17351

Petrović T, Poljarević J, Nikolić S, Stojković-Filipović J, Mihajlović-Lalić L. A review of the key ingredients in industrial formulations of baby wet wipes. in International Journal of Dermatology. 2024;n/a.
doi:10.1111/ijd.17351 .

Petrović, Tamara, Poljarević, Jelena, Nikolić, Stefan, Stojković-Filipović, Jelena, Mihajlović-Lalić, Ljiljana, "A review of the key ingredients in industrial formulations of baby wet wipes" in International Journal of Dermatology, n/a (2024),
https://doi.org/10.1111/ijd.17351 . .

TY  - JOUR
AU  - Savić, Slađana D.
AU  - Kovačević, Vesna V.
AU  - Stanković, Dalibor M.
AU  - Sretenović, Goran B.
AU  - Vasović, Tamara D.
AU  - Vlahović, Filip Ž.
AU  - Dojčinović, BIljana P.
AU  - Obradović, Bratislav M.
AU  - Kuraica, Milorad M.
AU  - Manojlović, Dragan D.
AU  - Roglić, Goran M.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6615
AB  - Propranolol, a beta-blocker, is a widely used drug for cardiovascular diseases. A synthetic sample containing propranolol (PRO) solution at native pH was recirculated up to ten times through an original coaxial non-thermal plasma reactor with a water falling film. Different discharge conditions, feed gasses, and power greatly influenced the extent of PRO degradation and the abundance of degradation products. The highest degradation rates were achieved in Ar plasma, either pure or in a mixture with O2, with over 70% of PRO degraded after only two passes through the DBD reactor. The full non-thermal plasma treatment was followed by a minimal change of pH value and conductivity. On the other hand, ambient air as the feed gas resulted in 60% of PRO degradation rate after the full treatment and contributed to a major drop in pH value and an increase in the conductivity of the treated solution. The structures of 47 degradation products in all three gases were identified and the degradation pathway is proposed, supported by DFT methodology. Scavenging experiments demonstrated that hydroxyl radical was predominant when plasma was generated using ambient air and Ar, while it had a minimal effect on the degradation in the mixture of Ar and O2. The desired level of propranolol decomposition was achieved only by the adjustment of the nonchemical parameters of the treatment, such as plasma gas composition and power. These results imply that a non-thermal plasma reactor is a highly effective method for pharmaceutical wastewater treatment, with no catalysts added.
PB  - Elsevier
T2  - Chemical Engineering Journal
T1  - Complete degradation of propranolol by a water falling film non-thermal plasma reactor: The effects of input power and plasma gases on transformation pathway
VL  - 497
SP  - 154685
DO  - 10.1016/j.cej.2024.154685
ER  - 

@article{
author = "Savić, Slađana D. and Kovačević, Vesna V. and Stanković, Dalibor M. and Sretenović, Goran B. and Vasović, Tamara D. and Vlahović, Filip Ž. and Dojčinović, BIljana P. and Obradović, Bratislav M. and Kuraica, Milorad M. and Manojlović, Dragan D. and Roglić, Goran M.",
year = "2024",
abstract = "Propranolol, a beta-blocker, is a widely used drug for cardiovascular diseases. A synthetic sample containing propranolol (PRO) solution at native pH was recirculated up to ten times through an original coaxial non-thermal plasma reactor with a water falling film. Different discharge conditions, feed gasses, and power greatly influenced the extent of PRO degradation and the abundance of degradation products. The highest degradation rates were achieved in Ar plasma, either pure or in a mixture with O2, with over 70% of PRO degraded after only two passes through the DBD reactor. The full non-thermal plasma treatment was followed by a minimal change of pH value and conductivity. On the other hand, ambient air as the feed gas resulted in 60% of PRO degradation rate after the full treatment and contributed to a major drop in pH value and an increase in the conductivity of the treated solution. The structures of 47 degradation products in all three gases were identified and the degradation pathway is proposed, supported by DFT methodology. Scavenging experiments demonstrated that hydroxyl radical was predominant when plasma was generated using ambient air and Ar, while it had a minimal effect on the degradation in the mixture of Ar and O2. The desired level of propranolol decomposition was achieved only by the adjustment of the nonchemical parameters of the treatment, such as plasma gas composition and power. These results imply that a non-thermal plasma reactor is a highly effective method for pharmaceutical wastewater treatment, with no catalysts added.",
publisher = "Elsevier",
journal = "Chemical Engineering Journal",
title = "Complete degradation of propranolol by a water falling film non-thermal plasma reactor: The effects of input power and plasma gases on transformation pathway",
volume = "497",
pages = "154685",
doi = "10.1016/j.cej.2024.154685"
}

Savić, S. D., Kovačević, V. V., Stanković, D. M., Sretenović, G. B., Vasović, T. D., Vlahović, F. Ž., Dojčinović, B. P., Obradović, B. M., Kuraica, M. M., Manojlović, D. D.,& Roglić, G. M.. (2024). Complete degradation of propranolol by a water falling film non-thermal plasma reactor: The effects of input power and plasma gases on transformation pathway. in Chemical Engineering Journal
Elsevier., 497, 154685.
https://doi.org/10.1016/j.cej.2024.154685

Savić SD, Kovačević VV, Stanković DM, Sretenović GB, Vasović TD, Vlahović FŽ, Dojčinović BP, Obradović BM, Kuraica MM, Manojlović DD, Roglić GM. Complete degradation of propranolol by a water falling film non-thermal plasma reactor: The effects of input power and plasma gases on transformation pathway. in Chemical Engineering Journal. 2024;497:154685.
doi:10.1016/j.cej.2024.154685 .

Savić, Slađana D., Kovačević, Vesna V., Stanković, Dalibor M., Sretenović, Goran B., Vasović, Tamara D., Vlahović, Filip Ž., Dojčinović, BIljana P., Obradović, Bratislav M., Kuraica, Milorad M., Manojlović, Dragan D., Roglić, Goran M., "Complete degradation of propranolol by a water falling film non-thermal plasma reactor: The effects of input power and plasma gases on transformation pathway" in Chemical Engineering Journal, 497 (2024):154685,
https://doi.org/10.1016/j.cej.2024.154685 . .

TY  - THES
AU  - Mijajlović, Aleksandar
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6651
AB  - Sve veći rast ljudske populacije praćen industrijalizacijom i intezivnom
poljoprivrednom proizvodnjom, povezan je sa problemima flore i faune i izaziva smanjenje
kvaliteta životne sredine, ostavljajući za sobom sve veću količinu opasnih pesticida.
U ovom radu, razvijen je novi elektrohemijski senzor za detekciju diurona (DU),
modifikujući već postojeću elektrodu od ugljenične paste (CPE) novosintetisanim Ho2O3
nanočesticama. Retki zemljini metali, kao što je Ho, sve više su popularni u razvoju novih
elektrodnih materijala zbog svojih elektrokatalitičkih performansi. Holmijum je glavni
lantanoidni element sa veoma širokim redoks-potencijalom. Sinteza Ho2O3 nanočestica urađena
je Pećini metodom sinteze, što je potvrđeno i difrakcijom X-zraka (XRD) kao i metodom
skenirajuće elektronske mikroskopije (SEM). U cilju razvoja nove metode za detekciju diurona,
ispitane su elektrokatalitičke osobine Ho2O3 modifikovane elektrode od ugljenične paste.
Elektrohemijsko ponašanje DU na novom senzoru ispitivano je koristeći cikličnu voltamteriju
(CV) kao i voltametriju pravougaonih talasa (square wave voltammetry, SWV). Senzor je
pokazao izvanredne rezultate, sa linearnim opsegom detekcije od 0.25 do 200 μM i limitom
detekcije od 0.03 μM, kao i osetljivošću od 2,14 μA μM−1 cm−2. Visoka selektivnost metode
potvrđena je analizom potencijalno interferirajućih supstanci. Dalje, CPE/Ho2O3 senzor
pokazao je veoma dobre vrednosti „recovery“-ja , pri detekciji DU u realnim uzorcima. Takođe,
praktična primena senzora u realnim uzorcima potvrđena je konvencionalnom metodom kao
što je spektrofotometrijska UV-VIS detekcija.
T1  - Pećini metoda sinteze Ho2O3 nanočestica i njiihova primena u razvoju visoko osetljivog elektrohemijskog senzora za detekciju diurona u realnim uzorcima
SP  - 1
EP  - 38
ER  - 

@mastersthesis{
author = "Mijajlović, Aleksandar",
year = "2024",
abstract = "Sve veći rast ljudske populacije praćen industrijalizacijom i intezivnom
poljoprivrednom proizvodnjom, povezan je sa problemima flore i faune i izaziva smanjenje
kvaliteta životne sredine, ostavljajući za sobom sve veću količinu opasnih pesticida.
U ovom radu, razvijen je novi elektrohemijski senzor za detekciju diurona (DU),
modifikujući već postojeću elektrodu od ugljenične paste (CPE) novosintetisanim Ho2O3
nanočesticama. Retki zemljini metali, kao što je Ho, sve više su popularni u razvoju novih
elektrodnih materijala zbog svojih elektrokatalitičkih performansi. Holmijum je glavni
lantanoidni element sa veoma širokim redoks-potencijalom. Sinteza Ho2O3 nanočestica urađena
je Pećini metodom sinteze, što je potvrđeno i difrakcijom X-zraka (XRD) kao i metodom
skenirajuće elektronske mikroskopije (SEM). U cilju razvoja nove metode za detekciju diurona,
ispitane su elektrokatalitičke osobine Ho2O3 modifikovane elektrode od ugljenične paste.
Elektrohemijsko ponašanje DU na novom senzoru ispitivano je koristeći cikličnu voltamteriju
(CV) kao i voltametriju pravougaonih talasa (square wave voltammetry, SWV). Senzor je
pokazao izvanredne rezultate, sa linearnim opsegom detekcije od 0.25 do 200 μM i limitom
detekcije od 0.03 μM, kao i osetljivošću od 2,14 μA μM−1 cm−2. Visoka selektivnost metode
potvrđena je analizom potencijalno interferirajućih supstanci. Dalje, CPE/Ho2O3 senzor
pokazao je veoma dobre vrednosti „recovery“-ja , pri detekciji DU u realnim uzorcima. Takođe,
praktična primena senzora u realnim uzorcima potvrđena je konvencionalnom metodom kao
što je spektrofotometrijska UV-VIS detekcija.",
title = "Pećini metoda sinteze Ho2O3 nanočestica i njiihova primena u razvoju visoko osetljivog elektrohemijskog senzora za detekciju diurona u realnim uzorcima",
pages = "1-38"
}

Mijajlović, A.. (2024). Pećini metoda sinteze Ho2O3 nanočestica i njiihova primena u razvoju visoko osetljivog elektrohemijskog senzora za detekciju diurona u realnim uzorcima. , 1-38.

Mijajlović A. Pećini metoda sinteze Ho2O3 nanočestica i njiihova primena u razvoju visoko osetljivog elektrohemijskog senzora za detekciju diurona u realnim uzorcima. 2024;:1-38..

Mijajlović, Aleksandar, "Pećini metoda sinteze Ho2O3 nanočestica i njiihova primena u razvoju visoko osetljivog elektrohemijskog senzora za detekciju diurona u realnim uzorcima" (2024):1-38.

TY  - CONF
AU  - Milovanović, Milan R.
AU  - Nikolić, Stefan
AU  - Dupé, Antoine
AU  - Poljarević, Jelena M.
AU  - Schachner, Jörg A.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6559
AB  - A lot of scientific effort was dedicated to research into a cure for cancer over past 
decades. Many of them failed due to a low solubility of synthetized compounds or low 
selectivity between healthy and pathogenic cells. It was shown that apigenin, a natural 
pigment of chamomile, showed some cytotoxic activity itself,[1] however, its extremely 
low solubility in water is a limiting factor in its use as a potential anticancer drug.
Here, we present a crystal structure of the first Re(V) complex containing apigenin 
– a natural occurring ligand. Various types of non-covalent interactions were found in 
the crystal structure (Figure 1). Namely, there are a couple of different hydrogen bonds 
(i.e. mono and bifurcated O-H∙∙∙O; O-H∙∙∙Cl; C-H∙∙∙Cl), T-shaped C-H∙∙∙π and π∙∙∙π 
stacking interactions. At least some of these interactions could be responsible for 
compounds’ final mechanism of anticancer action.
C3  - 3rd International Conferences on Noncovalent Interactions (ICNI2024), June 17th-21st 2024, Belgrade, Serbia
T1  - The first Re(V) Complex with a Ligand from the Nature: Non-Covalent Interactions from Crystal Structure
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6559
ER  - 

@conference{
author = "Milovanović, Milan R. and Nikolić, Stefan and Dupé, Antoine and Poljarević, Jelena M. and Schachner, Jörg A.",
year = "2024",
abstract = "A lot of scientific effort was dedicated to research into a cure for cancer over past 
decades. Many of them failed due to a low solubility of synthetized compounds or low 
selectivity between healthy and pathogenic cells. It was shown that apigenin, a natural 
pigment of chamomile, showed some cytotoxic activity itself,[1] however, its extremely 
low solubility in water is a limiting factor in its use as a potential anticancer drug.
Here, we present a crystal structure of the first Re(V) complex containing apigenin 
– a natural occurring ligand. Various types of non-covalent interactions were found in 
the crystal structure (Figure 1). Namely, there are a couple of different hydrogen bonds 
(i.e. mono and bifurcated O-H∙∙∙O; O-H∙∙∙Cl; C-H∙∙∙Cl), T-shaped C-H∙∙∙π and π∙∙∙π 
stacking interactions. At least some of these interactions could be responsible for 
compounds’ final mechanism of anticancer action.",
journal = "3rd International Conferences on Noncovalent Interactions (ICNI2024), June 17th-21st 2024, Belgrade, Serbia",
title = "The first Re(V) Complex with a Ligand from the Nature: Non-Covalent Interactions from Crystal Structure",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6559"
}

Milovanović, M. R., Nikolić, S., Dupé, A., Poljarević, J. M.,& Schachner, J. A.. (2024). The first Re(V) Complex with a Ligand from the Nature: Non-Covalent Interactions from Crystal Structure. in 3rd International Conferences on Noncovalent Interactions (ICNI2024), June 17th-21st 2024, Belgrade, Serbia.
https://hdl.handle.net/21.15107/rcub_cherry_6559

Milovanović MR, Nikolić S, Dupé A, Poljarević JM, Schachner JA. The first Re(V) Complex with a Ligand from the Nature: Non-Covalent Interactions from Crystal Structure. in 3rd International Conferences on Noncovalent Interactions (ICNI2024), June 17th-21st 2024, Belgrade, Serbia. 2024;.
https://hdl.handle.net/21.15107/rcub_cherry_6559 .

Milovanović, Milan R., Nikolić, Stefan, Dupé, Antoine, Poljarević, Jelena M., Schachner, Jörg A., "The first Re(V) Complex with a Ligand from the Nature: Non-Covalent Interactions from Crystal Structure" in 3rd International Conferences on Noncovalent Interactions (ICNI2024), June 17th-21st 2024, Belgrade, Serbia (2024),
https://hdl.handle.net/21.15107/rcub_cherry_6559 .

TY  - JOUR
AU  - Putica, Katarina B.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6527
AB  - As detection and subsequent remediation of misconceptions developed within high-school organic chemistry courses in regard to various classes of organic compounds are a prerequisite for meaningful learning of more advanced organic chemistry content, this study sought to identify high-school students’ misconceptions about alcohols and carbonyl compounds by means of a four-tier test. The test items comprise the answer and reason tier in a multiple-choice question format, and the response to each tier is accompanied by a confidence rating provided on a six-point confidence scale. The test was administered to 154 students, and evidence of satisfactory validity and internal consistency of both the cognitive scores and confidence ratings was obtained. Since a correct response to a four-tier item presupposes that both the answer and the reason tier within which all the distracters originate from the previously detected challenges with the above-mentioned content are answered correctly, the mean score on the test was predictably low. At the same time, the confidence ratings associated with the students’ incorrect responses enabled a more accurate differentiation between wrong answers caused by the lack of knowledge and the existence of misconceptions, compared to all of the other types of diagnostic tests that were previously implemented for this purpose. The identification of eight misconceptions about alcohols and carbonyl compounds within this study paves the way for the development of remediation approaches that would neutralize the negative impact of these conceptual difficulties on the meaningful learning of all related organic chemistry content.
PB  - American Chemical Society
PB  - Division of Chemical Education, Inc.
T2  - Journal of Chemical Education
T1  - Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test
VL  - 101
IS  - 4
SP  - 1442
EP  - 1456
DO  - 10.1021/acs.jchemed.3c01343
ER  - 

@article{
author = "Putica, Katarina B.",
year = "2024",
abstract = "As detection and subsequent remediation of misconceptions developed within high-school organic chemistry courses in regard to various classes of organic compounds are a prerequisite for meaningful learning of more advanced organic chemistry content, this study sought to identify high-school students’ misconceptions about alcohols and carbonyl compounds by means of a four-tier test. The test items comprise the answer and reason tier in a multiple-choice question format, and the response to each tier is accompanied by a confidence rating provided on a six-point confidence scale. The test was administered to 154 students, and evidence of satisfactory validity and internal consistency of both the cognitive scores and confidence ratings was obtained. Since a correct response to a four-tier item presupposes that both the answer and the reason tier within which all the distracters originate from the previously detected challenges with the above-mentioned content are answered correctly, the mean score on the test was predictably low. At the same time, the confidence ratings associated with the students’ incorrect responses enabled a more accurate differentiation between wrong answers caused by the lack of knowledge and the existence of misconceptions, compared to all of the other types of diagnostic tests that were previously implemented for this purpose. The identification of eight misconceptions about alcohols and carbonyl compounds within this study paves the way for the development of remediation approaches that would neutralize the negative impact of these conceptual difficulties on the meaningful learning of all related organic chemistry content.",
publisher = "American Chemical Society, Division of Chemical Education, Inc.",
journal = "Journal of Chemical Education",
title = "Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test",
volume = "101",
number = "4",
pages = "1442-1456",
doi = "10.1021/acs.jchemed.3c01343"
}

Putica, K. B.. (2024). Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test. in Journal of Chemical Education
American Chemical Society., 101(4), 1442-1456.
https://doi.org/10.1021/acs.jchemed.3c01343

Putica KB. Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test. in Journal of Chemical Education. 2024;101(4):1442-1456.
doi:10.1021/acs.jchemed.3c01343 .

Putica, Katarina B., "Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test" in Journal of Chemical Education, 101, no. 4 (2024):1442-1456,
https://doi.org/10.1021/acs.jchemed.3c01343 . .

TY  - JOUR
AU  - Trmčić, Milena
AU  - Vulović, Bojan
AU  - Zlatar, Matija
AU  - Saičić, Radomir
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6536
AB  - Hemiacetals of cyclopropanone can be isolated and stocked, contrary to their highly reactive parent ketone.  However, they are not readily converted to cyclopropanone, which limits their use as its synthetic equivalents.  2,2,2-trifluoroethoxy hemiacetals are expected to be better cyclopropanone surrogates, however, they have  never been prepared, so far. We show that oxyallyl cations with a heteroatom in the -position can be  intercepted with 2,2,2-trifluoroethanol, with formation of cyclopropanone trifluoroethoxy hemiacetals stable  enough to be isolated, purified and characterized. These species can serve as synthetic equivalents of  cyclopropanone under mild conditions.
PB  - ARKAT USA, Inc.
T2  - ARKIVOC - Online Journal of Organic Chemistry
T1  - Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation
VL  - 2024
IS  - 2
DO  - 10.24820/ark.5550190.p012.123
ER  - 

@article{
author = "Trmčić, Milena and Vulović, Bojan and Zlatar, Matija and Saičić, Radomir",
year = "2024",
abstract = "Hemiacetals of cyclopropanone can be isolated and stocked, contrary to their highly reactive parent ketone.  However, they are not readily converted to cyclopropanone, which limits their use as its synthetic equivalents.  2,2,2-trifluoroethoxy hemiacetals are expected to be better cyclopropanone surrogates, however, they have  never been prepared, so far. We show that oxyallyl cations with a heteroatom in the -position can be  intercepted with 2,2,2-trifluoroethanol, with formation of cyclopropanone trifluoroethoxy hemiacetals stable  enough to be isolated, purified and characterized. These species can serve as synthetic equivalents of  cyclopropanone under mild conditions.",
publisher = "ARKAT USA, Inc.",
journal = "ARKIVOC - Online Journal of Organic Chemistry",
title = "Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation",
volume = "2024",
number = "2",
doi = "10.24820/ark.5550190.p012.123"
}

Trmčić, M., Vulović, B., Zlatar, M.,& Saičić, R.. (2024). Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation. in ARKIVOC - Online Journal of Organic Chemistry
ARKAT USA, Inc.., 2024(2).
https://doi.org/10.24820/ark.5550190.p012.123

Trmčić M, Vulović B, Zlatar M, Saičić R. Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation. in ARKIVOC - Online Journal of Organic Chemistry. 2024;2024(2).
doi:10.24820/ark.5550190.p012.123 .

Trmčić, Milena, Vulović, Bojan, Zlatar, Matija, Saičić, Radomir, "Preparation of cyclopropanone 2,2,2-trifluoroethoxy hemiacetals via oxyallyl cation" in ARKIVOC - Online Journal of Organic Chemistry, 2024, no. 2 (2024),
https://doi.org/10.24820/ark.5550190.p012.123 . .

TY  - JOUR
AU  - Selaković, Snežana
AU  - Rodić, Marko V.
AU  - Novaković, Irena T.
AU  - Matić, Ivana Z.
AU  - Stanojković, Tatjana
AU  - Pirković, Andrea
AU  - Živković, Lada
AU  - Spremo-Potparević, Biljana
AU  - Milčić, Miloš
AU  - Medaković, Vesna
AU  - Dimiza, Filitsa
AU  - Psomas, George
AU  - Anđelković, Katarina K.
AU  - Šumar-Ristović, Maja
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6537
AB  - Copper(II) complexes with an α-diimine show a wide variety of biological activities, such as antibacterial, antifungal, antioxidant and anticancer. In this work, we synthesized and structurally characterized two novel Cu(II) complexes with methyl 3-formyl-4-hydroxybenzoate (HL) and α-diimines: 2,2′-bipyridine (bipy) and 1,10-phenanthroline (phen). Crystal structure analysis shows that the formulas of the compounds are [Cu(bipy)(L)(BF4)] (1) and [Cu(phen)(L)(H2O)](BF4)·H2O (2), with BF4− as a ligand in complex 1, which is rarely coordinated to metals. Both complexes have a square pyramidal geometry, while DFT calculations showed that the most stable structures of complexes 1 and 2 in a water/DMSO mixture are square-planar derivatives [Cu(bipy)(L)]+ and [Cu(phen)(L)]+. The antibacterial activity of compounds was evaluated in vitro on four Gram-negative and four Gram-positive bacterial strains. Complex 2 showed greater antibacterial activity towards all bacterial strains comparable to the control compound Amikacin. Complex 2 exerted a strong cytotoxic effect against the tested cancer cell lines (IC50 values ranging from 0.32 to 0.44 μM). Both complexes caused apoptotic cell death in HeLa cells and a noticeable in vitro antiangiogenic effect. In the concentration range of 5 to 100 μM, the complexes showed the absence of a genotoxic effect and displayed a protective effect against oxidative DNA damage induced by H2O2 in human peripheral blood cells. The interaction between the compounds and calf–thymus DNA was evaluated by diverse techniques suggesting a tight binding, which was also confirmed by molecular docking. In addition, it was found that the complexes bind tightly and reversibly to bovine and human serum albumin.
PB  - Royal Society of Chemistry
T2  - Dalton Transactions
T2  - Dalton TransactionsDalton Trans.
T1  - Cu(ii) complexes with a salicylaldehyde derivative and a-diimines as co-ligands: synthesis, characterization, biological activity. Experimental and theoretical approach
VL  - 53
IS  - 6
SP  - 2770
EP  - 2788
DO  - 10.1039/D3DT03862A
ER  - 

@article{
author = "Selaković, Snežana and Rodić, Marko V. and Novaković, Irena T. and Matić, Ivana Z. and Stanojković, Tatjana and Pirković, Andrea and Živković, Lada and Spremo-Potparević, Biljana and Milčić, Miloš and Medaković, Vesna and Dimiza, Filitsa and Psomas, George and Anđelković, Katarina K. and Šumar-Ristović, Maja",
year = "2024",
abstract = "Copper(II) complexes with an α-diimine show a wide variety of biological activities, such as antibacterial, antifungal, antioxidant and anticancer. In this work, we synthesized and structurally characterized two novel Cu(II) complexes with methyl 3-formyl-4-hydroxybenzoate (HL) and α-diimines: 2,2′-bipyridine (bipy) and 1,10-phenanthroline (phen). Crystal structure analysis shows that the formulas of the compounds are [Cu(bipy)(L)(BF4)] (1) and [Cu(phen)(L)(H2O)](BF4)·H2O (2), with BF4− as a ligand in complex 1, which is rarely coordinated to metals. Both complexes have a square pyramidal geometry, while DFT calculations showed that the most stable structures of complexes 1 and 2 in a water/DMSO mixture are square-planar derivatives [Cu(bipy)(L)]+ and [Cu(phen)(L)]+. The antibacterial activity of compounds was evaluated in vitro on four Gram-negative and four Gram-positive bacterial strains. Complex 2 showed greater antibacterial activity towards all bacterial strains comparable to the control compound Amikacin. Complex 2 exerted a strong cytotoxic effect against the tested cancer cell lines (IC50 values ranging from 0.32 to 0.44 μM). Both complexes caused apoptotic cell death in HeLa cells and a noticeable in vitro antiangiogenic effect. In the concentration range of 5 to 100 μM, the complexes showed the absence of a genotoxic effect and displayed a protective effect against oxidative DNA damage induced by H2O2 in human peripheral blood cells. The interaction between the compounds and calf–thymus DNA was evaluated by diverse techniques suggesting a tight binding, which was also confirmed by molecular docking. In addition, it was found that the complexes bind tightly and reversibly to bovine and human serum albumin.",
publisher = "Royal Society of Chemistry",
journal = "Dalton Transactions, Dalton TransactionsDalton Trans.",
title = "Cu(ii) complexes with a salicylaldehyde derivative and a-diimines as co-ligands: synthesis, characterization, biological activity. Experimental and theoretical approach",
volume = "53",
number = "6",
pages = "2770-2788",
doi = "10.1039/D3DT03862A"
}

Selaković, S., Rodić, M. V., Novaković, I. T., Matić, I. Z., Stanojković, T., Pirković, A., Živković, L., Spremo-Potparević, B., Milčić, M., Medaković, V., Dimiza, F., Psomas, G., Anđelković, K. K.,& Šumar-Ristović, M.. (2024). Cu(ii) complexes with a salicylaldehyde derivative and a-diimines as co-ligands: synthesis, characterization, biological activity. Experimental and theoretical approach. in Dalton Transactions
Royal Society of Chemistry., 53(6), 2770-2788.
https://doi.org/10.1039/D3DT03862A

Selaković S, Rodić MV, Novaković IT, Matić IZ, Stanojković T, Pirković A, Živković L, Spremo-Potparević B, Milčić M, Medaković V, Dimiza F, Psomas G, Anđelković KK, Šumar-Ristović M. Cu(ii) complexes with a salicylaldehyde derivative and a-diimines as co-ligands: synthesis, characterization, biological activity. Experimental and theoretical approach. in Dalton Transactions. 2024;53(6):2770-2788.
doi:10.1039/D3DT03862A .

Selaković, Snežana, Rodić, Marko V., Novaković, Irena T., Matić, Ivana Z., Stanojković, Tatjana, Pirković, Andrea, Živković, Lada, Spremo-Potparević, Biljana, Milčić, Miloš, Medaković, Vesna, Dimiza, Filitsa, Psomas, George, Anđelković, Katarina K., Šumar-Ristović, Maja, "Cu(ii) complexes with a salicylaldehyde derivative and a-diimines as co-ligands: synthesis, characterization, biological activity. Experimental and theoretical approach" in Dalton Transactions, 53, no. 6 (2024):2770-2788,
https://doi.org/10.1039/D3DT03862A . .

TY  - JOUR
AU  - Putica, Katarina B.
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6528
AB  - As detection and subsequent remediation of misconceptions developed within high-school organic chemistry courses in regard to various classes of organic compounds are a prerequisite for meaningful learning of more advanced organic chemistry content, this study sought to identify high-school students’ misconceptions about alcohols and carbonyl compounds by means of a four-tier test. The test items comprise the answer and reason tier in a multiple-choice question format, and the response to each tier is accompanied by a confidence rating provided on a six-point confidence scale. The test was administered to 154 students, and evidence of satisfactory validity and internal consistency of both the cognitive scores and confidence ratings was obtained. Since a correct response to a four-tier item presupposes that both the answer and the reason tier within which all the distracters originate from the previously detected challenges with the above-mentioned content are answered correctly, the mean score on the test was predictably low. At the same time, the confidence ratings associated with the students’ incorrect responses enabled a more accurate differentiation between wrong answers caused by the lack of knowledge and the existence of misconceptions, compared to all of the other types of diagnostic tests that were previously implemented for this purpose. The identification of eight misconceptions about alcohols and carbonyl compounds within this study paves the way for the development of remediation approaches that would neutralize the negative impact of these conceptual difficulties on the meaningful learning of all related organic chemistry content.
PB  - American Chemical Society
PB  - Division of Chemical Education, Inc.
T2  - Journal of Chemical Education
T1  - Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test
VL  - 101
IS  - 4
SP  - 1442
EP  - 1456
DO  - 10.1021/acs.jchemed.3c01343
ER  - 

@article{
author = "Putica, Katarina B.",
year = "2024",
abstract = "As detection and subsequent remediation of misconceptions developed within high-school organic chemistry courses in regard to various classes of organic compounds are a prerequisite for meaningful learning of more advanced organic chemistry content, this study sought to identify high-school students’ misconceptions about alcohols and carbonyl compounds by means of a four-tier test. The test items comprise the answer and reason tier in a multiple-choice question format, and the response to each tier is accompanied by a confidence rating provided on a six-point confidence scale. The test was administered to 154 students, and evidence of satisfactory validity and internal consistency of both the cognitive scores and confidence ratings was obtained. Since a correct response to a four-tier item presupposes that both the answer and the reason tier within which all the distracters originate from the previously detected challenges with the above-mentioned content are answered correctly, the mean score on the test was predictably low. At the same time, the confidence ratings associated with the students’ incorrect responses enabled a more accurate differentiation between wrong answers caused by the lack of knowledge and the existence of misconceptions, compared to all of the other types of diagnostic tests that were previously implemented for this purpose. The identification of eight misconceptions about alcohols and carbonyl compounds within this study paves the way for the development of remediation approaches that would neutralize the negative impact of these conceptual difficulties on the meaningful learning of all related organic chemistry content.",
publisher = "American Chemical Society, Division of Chemical Education, Inc.",
journal = "Journal of Chemical Education",
title = "Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test",
volume = "101",
number = "4",
pages = "1442-1456",
doi = "10.1021/acs.jchemed.3c01343"
}

Putica, K. B.. (2024). Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test. in Journal of Chemical Education
American Chemical Society., 101(4), 1442-1456.
https://doi.org/10.1021/acs.jchemed.3c01343

Putica KB. Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test. in Journal of Chemical Education. 2024;101(4):1442-1456.
doi:10.1021/acs.jchemed.3c01343 .

Putica, Katarina B., "Identification of High-School Students’ Conceptual Challenges Related to Alcohols and Carbonyl Compounds by Means of a Four-Tier Diagnostic Test" in Journal of Chemical Education, 101, no. 4 (2024):1442-1456,
https://doi.org/10.1021/acs.jchemed.3c01343 . .