Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort)
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Trifunović, Snežana S.
Karadžić, Ivanka M.
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Repeated examination of the aerial parts of Hypericum Perfomtum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3-pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli. (C) 2003 Elsevier Science B.V. All rights reserved.
Keywords:Hypericum perforatum / deoxyfurohyperforin A / antimicrobial activity
Source:Fitoterapia, 2003, 74, 5, 439-444
- Elsevier Science Bv, Amsterdam