We designed basket 1 to comprise a C-3-symmetric hydrophobic cage (477 angstrom(3)) at its southern edge and three polar ammonium caps at the northern edge. This amphiphilic molecule was observed to assemble into large unilamellar vesicles (350 nm, TEM) in water and thereby entrap dimethyl phenylphosphonate (184 angstrom(3)) in its cavity (K-app = (1.97 +/- 0.02) X 10(3) M-1). The entrapment of the organophosphonate, akin to soman in size (186 angstrom(3)), triggers the transformation of the vesicular material into nanoparticles (100 nm,of type 1 in their bilayer membrane, are unique assemblies and important for obtaining novel sensing devices.
Source:
Journal of the American Chemical Society, 2013, 135, 40, 14964-14967
Publisher:
Amer Chemical Soc, Washington
Funding / projects:
Department of Defense, Defense Threat Reduction Agency [HDTRA1-11-1-0042]
TY - JOUR
AU - Chen, Shigui
AU - Ruan, Yian
AU - Brown, Jason D.
AU - Gallucci, Judith
AU - Maslak, Veselin
AU - Hadad, Christopher M.
AU - Bađić, Jovica D.
PY - 2013
UR - https://cherry.chem.bg.ac.rs/handle/123456789/1427
AB - We designed basket 1 to comprise a C-3-symmetric hydrophobic cage (477 angstrom(3)) at its southern edge and three polar ammonium caps at the northern edge. This amphiphilic molecule was observed to assemble into large unilamellar vesicles (350 nm, TEM) in water and thereby entrap dimethyl phenylphosphonate (184 angstrom(3)) in its cavity (K-app = (1.97 +/- 0.02) X 10(3) M-1). The entrapment of the organophosphonate, akin to soman in size (186 angstrom(3)), triggers the transformation of the vesicular material into nanoparticles (100 nm,of type 1 in their bilayer membrane, are unique assemblies and important for obtaining novel sensing devices.
PB - Amer Chemical Soc, Washington
T2 - Journal of the American Chemical Society
T1 - Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents
VL - 135
IS - 40
SP - 14964
EP - 14967
DO - 10.1021/ja408585j
ER -
@article{
author = "Chen, Shigui and Ruan, Yian and Brown, Jason D. and Gallucci, Judith and Maslak, Veselin and Hadad, Christopher M. and Bađić, Jovica D.",
year = "2013",
abstract = "We designed basket 1 to comprise a C-3-symmetric hydrophobic cage (477 angstrom(3)) at its southern edge and three polar ammonium caps at the northern edge. This amphiphilic molecule was observed to assemble into large unilamellar vesicles (350 nm, TEM) in water and thereby entrap dimethyl phenylphosphonate (184 angstrom(3)) in its cavity (K-app = (1.97 +/- 0.02) X 10(3) M-1). The entrapment of the organophosphonate, akin to soman in size (186 angstrom(3)), triggers the transformation of the vesicular material into nanoparticles (100 nm,of type 1 in their bilayer membrane, are unique assemblies and important for obtaining novel sensing devices.",
publisher = "Amer Chemical Soc, Washington",
journal = "Journal of the American Chemical Society",
title = "Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents",
volume = "135",
number = "40",
pages = "14964-14967",
doi = "10.1021/ja408585j"
}
Chen, S., Ruan, Y., Brown, J. D., Gallucci, J., Maslak, V., Hadad, C. M.,& Bađić, J. D.. (2013). Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents. in Journal of the American Chemical Society
Amer Chemical Soc, Washington., 135(40), 14964-14967.
https://doi.org/10.1021/ja408585j
Chen S, Ruan Y, Brown JD, Gallucci J, Maslak V, Hadad CM, Bađić JD. Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents. in Journal of the American Chemical Society. 2013;135(40):14964-14967.
doi:10.1021/ja408585j .
Chen, Shigui, Ruan, Yian, Brown, Jason D., Gallucci, Judith, Maslak, Veselin, Hadad, Christopher M., Bađić, Jovica D., "Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents" in Journal of the American Chemical Society, 135, no. 40 (2013):14964-14967,
https://doi.org/10.1021/ja408585j . .
