New insight into the anisotropic effects in solution-state NMR spectroscopy
Abstract
Nuclear magnetic resonance (NMR) spectroscopy is an important technique for structure determination. Within it, anisotropic effects of different functional groups and ring systems, depicted as familiar "anisotropy cones", are broadly used to deduce the stereochemistry, for chemical shift assignments and to explain shielding or deshielding of nuclei spatially close, or directly attached to the corresponding functional group, or ring. Progress in computational methods has enabled the quantification of anisotropic effects, an insight into their origin and to the source of (de) shielding of proximal nucleus. Some widely accepted traditional explanations, presented in NMR spectroscopy textbooks, have been questioned. The purpose of this review is to collect and discuss the research, mainly based on theoretical calculations, that provided new insight into the anisotropic effects, their origin and factors responsible for (de) shielding of proximal protons.
Source:
RSC Advances, 2014, 4, 1, 308-321Publisher:
- Royal Soc Chemistry, Cambridge
Funding / projects:
- Experimental and theoretical study of reactivity and biological activity of stereodefined thiazolidines and their synthetic analogues (RS-MESTD-Basic Research (BR or ON)-172020)
DOI: 10.1039/c3ra45512b
ISSN: 2046-2069
WoS: 000327547000042
Scopus: 2-s2.0-84888599731
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Baranac-Stojanović, Marija PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1445 AB - Nuclear magnetic resonance (NMR) spectroscopy is an important technique for structure determination. Within it, anisotropic effects of different functional groups and ring systems, depicted as familiar "anisotropy cones", are broadly used to deduce the stereochemistry, for chemical shift assignments and to explain shielding or deshielding of nuclei spatially close, or directly attached to the corresponding functional group, or ring. Progress in computational methods has enabled the quantification of anisotropic effects, an insight into their origin and to the source of (de) shielding of proximal nucleus. Some widely accepted traditional explanations, presented in NMR spectroscopy textbooks, have been questioned. The purpose of this review is to collect and discuss the research, mainly based on theoretical calculations, that provided new insight into the anisotropic effects, their origin and factors responsible for (de) shielding of proximal protons. PB - Royal Soc Chemistry, Cambridge T2 - RSC Advances T1 - New insight into the anisotropic effects in solution-state NMR spectroscopy VL - 4 IS - 1 SP - 308 EP - 321 DO - 10.1039/c3ra45512b ER -
@article{ author = "Baranac-Stojanović, Marija", year = "2014", abstract = "Nuclear magnetic resonance (NMR) spectroscopy is an important technique for structure determination. Within it, anisotropic effects of different functional groups and ring systems, depicted as familiar "anisotropy cones", are broadly used to deduce the stereochemistry, for chemical shift assignments and to explain shielding or deshielding of nuclei spatially close, or directly attached to the corresponding functional group, or ring. Progress in computational methods has enabled the quantification of anisotropic effects, an insight into their origin and to the source of (de) shielding of proximal nucleus. Some widely accepted traditional explanations, presented in NMR spectroscopy textbooks, have been questioned. The purpose of this review is to collect and discuss the research, mainly based on theoretical calculations, that provided new insight into the anisotropic effects, their origin and factors responsible for (de) shielding of proximal protons.", publisher = "Royal Soc Chemistry, Cambridge", journal = "RSC Advances", title = "New insight into the anisotropic effects in solution-state NMR spectroscopy", volume = "4", number = "1", pages = "308-321", doi = "10.1039/c3ra45512b" }
Baranac-Stojanović, M.. (2014). New insight into the anisotropic effects in solution-state NMR spectroscopy. in RSC Advances Royal Soc Chemistry, Cambridge., 4(1), 308-321. https://doi.org/10.1039/c3ra45512b
Baranac-Stojanović M. New insight into the anisotropic effects in solution-state NMR spectroscopy. in RSC Advances. 2014;4(1):308-321. doi:10.1039/c3ra45512b .
Baranac-Stojanović, Marija, "New insight into the anisotropic effects in solution-state NMR spectroscopy" in RSC Advances, 4, no. 1 (2014):308-321, https://doi.org/10.1039/c3ra45512b . .