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dc.creatorPerušković, Danica S.
dc.creatorStevanović, Nikola R.
dc.creatorLolić, Aleksandar
dc.creatorBaošić, Rada
dc.date.accessioned2018-11-22T00:27:11Z
dc.date.available2018-11-22T00:27:11Z
dc.date.issued2014
dc.identifier.issn1570-1808
dc.identifier.urihttps://cherry.chem.bg.ac.rs/handle/123456789/1508
dc.description.abstractThe objectives of this study were to gain insights into the structure-retention and structure-lipophilicity relationships of series of twenty antidepressants and to propose model for estimating their retention and lipophilicity. The lipophilicity of antidepressants has been determined by reversed-phase thin-layer chromatography using binary methanol-water mobile phases. The chemical structures of the antidepressants have been characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters as well as chromatographically determinated lipophilicity parameters by multiple linear regression analysis. The obtained models were used for interpretation of the lipophilicity and retention behavior of the investigated compounds.en
dc.publisherBentham Science Publ Ltd, Sharjah
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172017/RS//
dc.rightsrestrictedAccess
dc.sourceLetters in Drug Design and Discovery
dc.subjectAntidepressantsen
dc.subjectLipophilicityen
dc.subjectQSARen
dc.subjectQSRRen
dc.subjectReversed-phase thin layer chromatographyen
dc.titleCorrelation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studiesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractПерусковиц, Даница С.; Лолић, Aлександар; Стевановић, Никола; Баошић, Рада;
dc.citation.volume11
dc.citation.issue2
dc.citation.spage162
dc.citation.epage168
dc.identifier.wos000331886300006
dc.citation.other11(2): 162-168
dc.citation.rankM23
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-84893757043
dc.identifier.rcubKon_2628
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_cherry_1508


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