Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals
Само за регистроване кориснике
2014
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A sensitive, selective and reliable electrochemical method for the determination of nicotine using differential pulse voltammetry on a bare boron-doped diamond electrode has been developed. Nicotine yielded a single oxidation peak at a highly positive potential of +1.45 V (vs. Ag/AgCl/3 M KCl) in Britton-Robinson buffer solution at pH 8. The influence of supporting electrolyte, pH and scan rate on the current response of NIC was investigated. At optimized experimental conditions, a linear relation between peak current and concentration of nicotine was found for the range from 0.5 to 200 mu M (0.08-32.9 mg L-1) with a detection limit of 0.3 mu M (0.05 mg L-1) and a good repeatability (relative standard deviation of 2.1% at 25 mu M concentration level, n = 10) was achieved without any electrode surface modification. The practical usefulness of the developed procedure was successfully demonstrated with the determination of nicotine in tobacco products and anti-smoking pharmaceuticals with... results similar to those obtained by a high-performance liquid chromatography and to the contents declared by the manufacturer, respectively. Prior to analysis, the sample pretreatment includes only sonication and/or simple liquid-liquid extraction. The proposed sensor represents an effective electrochemical tool and a promising alternative for quality control analysis of products in tobacco and pharmaceutical industry. (C) 2013 Elsevier B.V. All rights reserved.
Кључне речи:
Nicotine / Oxidation / Boron-doped diamond electrode / Voltammetry / Tobacco product / Anti-smoking pharmaceuticalИзвор:
Diamond and Related Materials, 2014, 42, 1-7Издавач:
- Elsevier Science Sa, Lausanne
Финансирање / пројекти:
- Примена унапређених оксидационих процеса и наноструктурисаних оксидних материјала за уклањање загађивача из животне средине, развој и оптимизација инструменталних техника за праћење ефикасности (RS-172030)
- Bilateral program Action: Austria-Slovakia
- Grant Agency of the Slovak Republic [1/0051/13]
- Slovak Research and Development Agency [APVV-0797-11]
DOI: 10.1016/j.diamond.2013.11.012
ISSN: 0925-9635
WoS: 000332910400002
Scopus: 2-s2.0-84896539707
Колекције
Институција/група
Inovacioni centar / Innovation CentreTY - JOUR AU - Šovrc, Ľubomír AU - Stanković, Dalibor AU - Kalcher, Kurt PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1514 AB - A sensitive, selective and reliable electrochemical method for the determination of nicotine using differential pulse voltammetry on a bare boron-doped diamond electrode has been developed. Nicotine yielded a single oxidation peak at a highly positive potential of +1.45 V (vs. Ag/AgCl/3 M KCl) in Britton-Robinson buffer solution at pH 8. The influence of supporting electrolyte, pH and scan rate on the current response of NIC was investigated. At optimized experimental conditions, a linear relation between peak current and concentration of nicotine was found for the range from 0.5 to 200 mu M (0.08-32.9 mg L-1) with a detection limit of 0.3 mu M (0.05 mg L-1) and a good repeatability (relative standard deviation of 2.1% at 25 mu M concentration level, n = 10) was achieved without any electrode surface modification. The practical usefulness of the developed procedure was successfully demonstrated with the determination of nicotine in tobacco products and anti-smoking pharmaceuticals with results similar to those obtained by a high-performance liquid chromatography and to the contents declared by the manufacturer, respectively. Prior to analysis, the sample pretreatment includes only sonication and/or simple liquid-liquid extraction. The proposed sensor represents an effective electrochemical tool and a promising alternative for quality control analysis of products in tobacco and pharmaceutical industry. (C) 2013 Elsevier B.V. All rights reserved. PB - Elsevier Science Sa, Lausanne T2 - Diamond and Related Materials T1 - Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals VL - 42 SP - 1 EP - 7 DO - 10.1016/j.diamond.2013.11.012 ER -
@article{ author = "Šovrc, Ľubomír and Stanković, Dalibor and Kalcher, Kurt", year = "2014", abstract = "A sensitive, selective and reliable electrochemical method for the determination of nicotine using differential pulse voltammetry on a bare boron-doped diamond electrode has been developed. Nicotine yielded a single oxidation peak at a highly positive potential of +1.45 V (vs. Ag/AgCl/3 M KCl) in Britton-Robinson buffer solution at pH 8. The influence of supporting electrolyte, pH and scan rate on the current response of NIC was investigated. At optimized experimental conditions, a linear relation between peak current and concentration of nicotine was found for the range from 0.5 to 200 mu M (0.08-32.9 mg L-1) with a detection limit of 0.3 mu M (0.05 mg L-1) and a good repeatability (relative standard deviation of 2.1% at 25 mu M concentration level, n = 10) was achieved without any electrode surface modification. The practical usefulness of the developed procedure was successfully demonstrated with the determination of nicotine in tobacco products and anti-smoking pharmaceuticals with results similar to those obtained by a high-performance liquid chromatography and to the contents declared by the manufacturer, respectively. Prior to analysis, the sample pretreatment includes only sonication and/or simple liquid-liquid extraction. The proposed sensor represents an effective electrochemical tool and a promising alternative for quality control analysis of products in tobacco and pharmaceutical industry. (C) 2013 Elsevier B.V. All rights reserved.", publisher = "Elsevier Science Sa, Lausanne", journal = "Diamond and Related Materials", title = "Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals", volume = "42", pages = "1-7", doi = "10.1016/j.diamond.2013.11.012" }
Šovrc, Ľ., Stanković, D.,& Kalcher, K.. (2014). Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals. in Diamond and Related Materials Elsevier Science Sa, Lausanne., 42, 1-7. https://doi.org/10.1016/j.diamond.2013.11.012
Šovrc Ľ, Stanković D, Kalcher K. Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals. in Diamond and Related Materials. 2014;42:1-7. doi:10.1016/j.diamond.2013.11.012 .
Šovrc, Ľubomír, Stanković, Dalibor, Kalcher, Kurt, "Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals" in Diamond and Related Materials, 42 (2014):1-7, https://doi.org/10.1016/j.diamond.2013.11.012 . .