Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method
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2015
Authors
Stanić, VojislavRadosavljević-Mihajlović, Ana S.
Živković-Radovanović, Vukosava
Nastasijevic, Branislav
Marinovic-Cincovic, Milena
Marković, Jelena
Budimir, Milica D.
Article (Published version)
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Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)(2). The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FUR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of AW-doped fluorapatite particles which may lead to their death.... The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry. (C) 2015 Elsevier B.V. All rights reserved.
Keywords:
Fluoroapatite / Silver / Biomaterials / Antibacterial / Neutralization methodSource:
Applied Surface Science, 2015, 337, 72-80Publisher:
- Elsevier Science Bv, Amsterdam
Funding / projects:
- Advanced technologies for monitoring and environmental protection from chemical pollutants and radiation burden (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-43009)
DOI: 10.1016/j.apsusc.2015.02.065
ISSN: 0169-4332
WoS: 000351621000011
Scopus: 2-s2.0-84925363046
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Stanić, Vojislav AU - Radosavljević-Mihajlović, Ana S. AU - Živković-Radovanović, Vukosava AU - Nastasijevic, Branislav AU - Marinovic-Cincovic, Milena AU - Marković, Jelena AU - Budimir, Milica D. PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1679 AB - Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)(2). The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FUR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of AW-doped fluorapatite particles which may lead to their death. The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry. (C) 2015 Elsevier B.V. All rights reserved. PB - Elsevier Science Bv, Amsterdam T2 - Applied Surface Science T1 - Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method VL - 337 SP - 72 EP - 80 DO - 10.1016/j.apsusc.2015.02.065 ER -
@article{ author = "Stanić, Vojislav and Radosavljević-Mihajlović, Ana S. and Živković-Radovanović, Vukosava and Nastasijevic, Branislav and Marinovic-Cincovic, Milena and Marković, Jelena and Budimir, Milica D.", year = "2015", abstract = "Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)(2). The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FUR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of AW-doped fluorapatite particles which may lead to their death. The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry. (C) 2015 Elsevier B.V. All rights reserved.", publisher = "Elsevier Science Bv, Amsterdam", journal = "Applied Surface Science", title = "Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method", volume = "337", pages = "72-80", doi = "10.1016/j.apsusc.2015.02.065" }
Stanić, V., Radosavljević-Mihajlović, A. S., Živković-Radovanović, V., Nastasijevic, B., Marinovic-Cincovic, M., Marković, J.,& Budimir, M. D.. (2015). Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method. in Applied Surface Science Elsevier Science Bv, Amsterdam., 337, 72-80. https://doi.org/10.1016/j.apsusc.2015.02.065
Stanić V, Radosavljević-Mihajlović AS, Živković-Radovanović V, Nastasijevic B, Marinovic-Cincovic M, Marković J, Budimir MD. Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method. in Applied Surface Science. 2015;337:72-80. doi:10.1016/j.apsusc.2015.02.065 .
Stanić, Vojislav, Radosavljević-Mihajlović, Ana S., Živković-Radovanović, Vukosava, Nastasijevic, Branislav, Marinovic-Cincovic, Milena, Marković, Jelena, Budimir, Milica D., "Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method" in Applied Surface Science, 337 (2015):72-80, https://doi.org/10.1016/j.apsusc.2015.02.065 . .