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9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation
dc.creator | Veljović, Elma | |
dc.creator | Špirtović-Halilović, Selma | |
dc.creator | Muratovic, Samija | |
dc.creator | Zulj, Lidija Valek | |
dc.creator | Roca, Sunčica | |
dc.creator | Trifunović, Snežana S. | |
dc.creator | Osmanović, Amar | |
dc.creator | Završnik, Davorka | |
dc.date.accessioned | 2018-11-22T00:32:01Z | |
dc.date.available | 2018-11-22T00:32:01Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 0011-1643 | |
dc.identifier.uri | https://cherry.chem.bg.ac.rs/handle/123456789/1743 | |
dc.description.abstract | Oxidative stress is directly related to several diseases and symptoms, where antioxidant compounds, such as xanthenes, may become important in prevention and/or treatmant. Ten biologically active 9-aryl substituted 2,6,7-trihydroxyxanthen-3-one derivatives were synthesized using reliable one-pot synthesis and their structures were confirmed by IR, H-1 and C-13 NMR spectroscopy and mass spectrometry. Some of the synthesized compounds were scanned for their antioxidant potency using electrochemical method cyclic voltammetry of immobilized microparticles. Substitution of hydrogen at the phenyl ring of 2,6,7-trihydroxy-9-phenylxanthen-3-one with an electron-donating group affected the reducing power of the compounds by lowering the biological oxidation potential. These results signify the importance of xanthen-3-one derivatives as antioxidant agents and their further biological evaluation. | en |
dc.publisher | Croatian Chemical Soc, Zagreb | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Croatica Chemica Acta | |
dc.subject | xanthen-3-one derivatives | en |
dc.subject | antioxidant potency | en |
dc.subject | cyclic voltammetry | en |
dc.title | 9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation | en |
dc.type | article | |
dc.rights.license | BY | |
dcterms.abstract | Муратовиц, Самија; Заврсник, Даворка; Вељовиц, Елма; Зуљ, Лидија Валек; Трифуновић, Снежана; Спиртовиц-Халиловиц, Селма; Роца, Сунцица; Османовиц, Aмар; | |
dc.citation.volume | 88 | |
dc.citation.issue | 2 | |
dc.citation.spage | 121 | |
dc.citation.epage | 127 | |
dc.identifier.wos | 000358441800004 | |
dc.identifier.doi | 10.5562/cca2595 | |
dc.citation.other | 88(2): 121-127 | |
dc.citation.rank | M23 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-84938378595 | |
dc.identifier.fulltext | https://cherry.chem.bg.ac.rs/bitstream/id/8814/1741.pdf |