Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes
Само за регистроване кориснике
2014
Аутори
Filipović, Nenad R.Polović, Natalija
Rašković, Brankica
Misirlić-Denčić, Sonja
Dulović, Marija
Savić, Milena
Nikšić, Miomir
Mitić, Dragana
Anđelković, Katarina K.
Todorović, Tamara
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus.
Кључне речи:
Antimicrobial activity / Antioxidants / Cytotoxicity / Coordination chemistry / Schiff basesИзвор:
Monatshefte Fur Chemie, 2014, 145, 7, 1089-1099Издавач:
- Springer Wien, Wien
Финансирање / пројекти:
- Интеракције природних производа, њихових деривата и комплексних једињења са протеинима и нуклеинским киселинама (RS-172055)
- Модулација сигналних путева који контролишу интрацелуларни енергетски баланс у терапији тумора и неуро-имуно-ендокриних поремећаја (RS-41025)
- Развој нових инкапсулационих и ензимских технологија за производњу биокатализатора и биолошки активних компонената хране у циљу повећања њене конкурентности, квалитета и безбедности (RS-46010)
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3683
DOI: 10.1007/s00706-014-1197-6
ISSN: 0026-9247
WoS: 000337046200006
Scopus: 2-s2.0-84902270174
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Filipović, Nenad R. AU - Polović, Natalija AU - Rašković, Brankica AU - Misirlić-Denčić, Sonja AU - Dulović, Marija AU - Savić, Milena AU - Nikšić, Miomir AU - Mitić, Dragana AU - Anđelković, Katarina K. AU - Todorović, Tamara PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1787 AB - New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus. PB - Springer Wien, Wien T2 - Monatshefte Fur Chemie T1 - Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes VL - 145 IS - 7 SP - 1089 EP - 1099 DO - 10.1007/s00706-014-1197-6 ER -
@article{ author = "Filipović, Nenad R. and Polović, Natalija and Rašković, Brankica and Misirlić-Denčić, Sonja and Dulović, Marija and Savić, Milena and Nikšić, Miomir and Mitić, Dragana and Anđelković, Katarina K. and Todorović, Tamara", year = "2014", abstract = "New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus.", publisher = "Springer Wien, Wien", journal = "Monatshefte Fur Chemie", title = "Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes", volume = "145", number = "7", pages = "1089-1099", doi = "10.1007/s00706-014-1197-6" }
Filipović, N. R., Polović, N., Rašković, B., Misirlić-Denčić, S., Dulović, M., Savić, M., Nikšić, M., Mitić, D., Anđelković, K. K.,& Todorović, T.. (2014). Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes. in Monatshefte Fur Chemie Springer Wien, Wien., 145(7), 1089-1099. https://doi.org/10.1007/s00706-014-1197-6
Filipović NR, Polović N, Rašković B, Misirlić-Denčić S, Dulović M, Savić M, Nikšić M, Mitić D, Anđelković KK, Todorović T. Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes. in Monatshefte Fur Chemie. 2014;145(7):1089-1099. doi:10.1007/s00706-014-1197-6 .
Filipović, Nenad R., Polović, Natalija, Rašković, Brankica, Misirlić-Denčić, Sonja, Dulović, Marija, Savić, Milena, Nikšić, Miomir, Mitić, Dragana, Anđelković, Katarina K., Todorović, Tamara, "Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes" in Monatshefte Fur Chemie, 145, no. 7 (2014):1089-1099, https://doi.org/10.1007/s00706-014-1197-6 . .