Now showing items 1-10 of 544
Formal Synthesis of (-)-Oseltamivir Phosphate
(Georg Thieme Verlag Kg, Stuttgart, 2013)
The formal synthesis of (-)-oseltamivir phosphate (Tamiflu (TM)) was accomplished starting from (S)-pyroglutamic acid. The synthesis comprised two carbon-carbon bond forming reactions, the first one being a diastereoselective, ...
Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester
(Springer Wien, Wien, 2009)
The electrospray mass spectrometric (ESI-MS) behavior of the complexes trans-dichloro(ethylenediamine-N, N'-di-3-propionato) platinum(IV), trans-dibromo(ethylenediamine-N, N'-di-3-propionato) platinum( IV), dichloro ...
pH-Dependent Leaching of Dump Coal Ash-Retrospective Environmental Analysis
(Taylor & Francis Inc, Philadelphia, 2009)
Trace and major elements in coal ash particles from dump of "Nikola Tesla A" power plant in Obrenovac near Belgrade (Serbia) can cause pollution, due to leaching by atmospheric and surface waters. In order to assess this ...
Defensive Secretions in Three Species of Polydesmids (Diplopoda, Polydesmida, Polydesmidae)
(Springer, Dordrecht, 2010)
Nine compounds were detected in three different millipede species: Polydesmus complanatus (L.), Brachydesmus (Stylobrachydesmus) avalae A dagger uriA double dagger & Makarov, and Brachydesmus (Stylobrachydesmus) dadayi ...
Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
Based on biological properties of epoxyquinols from natural sources, bromo and epoxyquinols derived from estrone were synthesized and screened against Fem-X. HeLa and K-562 cell lines. Evidence was found that the bromine ...
Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells
(Springer, Dordrecht, 2009)
In this study we investigated the antiproliferative activity of six mixed steroidal tetraoxanes against various tumor cell lines, the toxicity against normal peripheral blood mononuclear cells (PBMC), and the mode of HeLa ...
Flow cytometry based high throughput screening system for screening and improving industrially important enzymes
(Elsevier Science Bv, Amsterdam, 2009)
Dietary lipid intake influences the level of cholesterol bound to haemoglobin in human erythrocytes
(Springer Heidelberg, Heidelberg, 2008)
Background Blood cholesterol levels are affected by diet and in particular by the type of fat intake. We originally showed that a significant but variable amount of cholesterol is firmly bound to haemoglobin (Hb) yielding ...
Synthesis, characterization, DFT calculations and antimicrobial activity of Cd(II) complexes with the condensation product of 2-quinolinecarboxaldehyde and Girard's T reagent
(Taylor & Francis Ltd, Abingdon, 2017)
The chloro (1) and isocyanato (2) Cd(II) complexes with the condensation product of 2-quinolinecarboxaldehyde and trimethylammonium acetohydrazide chloride (Girard's T reagent) (HLCl) have been synthesized and characterized ...
Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
Snakebites represent an important public health problem, with a great number of victims with permanent sequelae or fatal outcomes, particularly in rural, agriculturally active areas. The snake venom metalloproteases (SVMPs) ...