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4-Amino-7-chloroquinolines: Probing Ligand Efficiency Provides Botulinum Neurotoxin Serotype A Light Chain Inhibitors with Significant Antiprotozoal Activity
(Amer Chemical Soc, Washington, 2013)
Structurally simplified analogues of dual antimalarial and botulinum neurotoxin serotype A light chain (BoNT/A LC) inhibitor bis-aminoquinoline (1) were prepared. New compounds were designed to improve ligand efficiency ...
Investigation of nanocrystalline phases in Li-La-Fe-O system formed by the decomposition of acetylacetonato complexes
(Elsevier Science Sa, Lausanne, 2007)
Applying a new synthesis route based on the thermal decomposition of a mixture acetylacetonato complexes, Li(AA), La(AA)(3) and Fe(AA)(3), Li, La ferrite (Li0.5La0.08Fe2.42O4) was formed. The element analysis performed by ...
Distribution and fractionation of heavy metals in the Tisa (Tisza) River sediments
(Ecomed Publishers, Landsberg, 2007)
Introduction. In this work, sediments of the River Tisa (Tisza) are studied to assess their environmental pollution levels for some major heavy metals, as well as to predict the investigated elements' mobility on the basis ...
Macromolecular crowding conditions enhance glycation and oxidation of whey proteins in ultrasound-induced Maillard reaction
(Elsevier Sci Ltd, Oxford, 2015)
High intensity ultrasound (HIUS) can promote Maillard reaction (MR). Macromolecular crowding conditions accelerate reactions and stabilise protein structure. The aim of this study was to investigate if combined application ...
Total Synthesis of (-)-atrop-Abyssomicin C
(Wiley-V C H Verlag Gmbh, Weinheim, 2012)
Stevens-Johnson syndrome and toxic epidermal necrolysis in children
(Wiley, Hoboken, 2013)
A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype a metalloprotease
(Amer Chemical Soc, Washington, 2007)
We previously identified structurally diverse small molecule (non-peptidic) inhibitors (SMNPIs) of the botulinum neurotoxin serotype A (BoNT/A) light chain (LC). Of these, several (including antimalarial drugs) contained ...
Characterisation of a thaumatin-like homologue from birch (Betula verrucosa) pollen
(Wiley-Blackwell Publishing, Inc, Malden, 2009)
Ring-closing metathesis/fragmentation route to geometrically defined medium-ring cycloalkenes: Total synthesis of (+/-)-periplanone C
(Amer Chemical Soc, Washington, 2004)
[GRAPHICS] The combination of alkene metathesis and beta-fragmentation offers an efficient entry into (Z)-configured medium-ring cycloalkenes. The versatility of this method is demonstrated by the total synthesis of ...
Urinary activity of N-acetyl beta-glucosaminidase (NAG) is an indicator of short and long-term metabolic control
(Springer-Verlag, New York, 2001)