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Conserved Structural Motif for Recognizing Nicotinamide Adenine Dinucleotide in Poly(ADP-ribose) Polymerases and ADP-Ribosylating Toxins: Implications for Structure-Based Drug Design
(Amer Chemical Soc, Washington, 2010)
The ADP-ribosylating toxins (ADPRTs) and poly(ADP-ribose) polymerases (PARPs) are two important drug target protein families. Although the Y-X(10)-Y motif for the diphtheria toxin group and the STS motif for the other ...
Eco-chemical status of the Korbevacka River in souht-eastern Serbia
(Parlar Scientific Publications (P S P), Freising, 2007)
The Korbevacka River is located in the south-eastern part of Serbia. This river is a main recipient of all kinds of pollutants from the local Pb-Zn mine "Grot". Determination of the eco-chemical status comprised complete ...
2-Alkylidene-4-oxothiazolidine S-oxides: synthesis and stereochemistry
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
A series of 5-unsubstituted and 5-substituted 2-alkylidene-4-oxothiazolidine-S-oxides were synthesized by the sulfur-oxidation with m-CPBA. The stereochemistry of 5-substituted sulfoxides was determined by means of NMR ...
Transition metal complexes with thiosemicarbazide-based ligands. part 37. Synthesis and study of the first thiosemi-carbazide-derived copper(I) complexes: Crystal structure of [2-(diphenylphosphino)benzaldehyde thiosemicarbazonato(-l)] copper(I)nitrate-me
(Taylor & Francis Ltd, Abingdon, 2000)
The preparation and physical characterization of two copper(I) complexes Cu(HL)NO3 and [Cu(HL)(2)]NO3 . MeOH formed with a newly synthesized tridentate [S,N,P] HL = 2-(diphenylphosphino)benzaldehyde thiosemicarbazone ligand ...
Carbon-bromine cleavage by dimethyl sulfoxide: the key step of C(5) functionalization of push-pull 2-alkylidene-4-oxothiazolidine vinyl bromides
(Pergamon-Elsevier Science Ltd, Oxford, 2007)
Push-pull 2-alkylidene-4-oxothiazolidine vinyl bromides undergo efficient C(5) functionalization through DMSO-assisted carbon-bromine cleavage, followed by a bromine transfer-substitution (or elimination) sequence. A ...
Quantitative Structure-Retention Relationships of Mixed Tris-beta-Diketonato Complexes on Polyacrylonitrile Sorbent
(Vieweg, Wiesbaden, 2008)
Quantitative structure-retention relationships models have been developed for thin-layer chromatographic parameters of 30 mixed beta-diketonato complexes. In order to obtain predictive and interpretative models, we ...
Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
(Nature Publishing Group, New York, 2017)
Polypeptides and polynucleotides are natural programmable biopolymers that can self-assemble into complex tertiary structures. We describe a system analogous to designed DNA nanostructures in which protein coiled-coil (CC) ...
Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids
(Wiley-Blackwell, Malden, 2010)
New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix ...
A modification of the kinetic determination of pancuronium bromide based on its inhibitory effect on cholinesterase
(Wiley-Liss, Hoboken, 2007)
A modification of the existing spectrophotometric kinetic method for the determination of pancuronium bromide (PCBr), based on pooled human serum cholinesterase (ChE, EC 3.1.1.8 acylcholine acylhydrolase) inhibition, was ...
Insights into proteolytic processing of the major peanut allergen Ara h 2 by endogenous peanut proteases
(John Wiley & Sons Ltd, Chichester, 2010)
BACKGROUND: The major peanut allergens are Ara h 1, Ara h 2 and Ara h 6. Proteolytic processing has been shown to be required for the maturation process of Ara h 6. The aim of this study was to examine whether Ara h 2 ...