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Conserved Structural Motif for Recognizing Nicotinamide Adenine Dinucleotide in Poly(ADP-ribose) Polymerases and ADP-Ribosylating Toxins: Implications for Structure-Based Drug Design
(Amer Chemical Soc, Washington, 2010)
The ADP-ribosylating toxins (ADPRTs) and poly(ADP-ribose) polymerases (PARPs) are two important drug target protein families. Although the Y-X(10)-Y motif for the diphtheria toxin group and the STS motif for the other ...
Radical, one-step approach to o-chlorophenyl thioethers from xanthates. A rapid access to vinylsilanes
(Amer Chemical Soc, Washington, 2008)
Xanthates have been readily converted into o-chlorophenyl thioethers using a one-step procedure conducted under radical conditions. In some selected cases, these aryl thioethers were successfully oxidized to the corresponding ...
Cyclohexane oxidation and cyclohexyl hydroperoxide decomposition by poly(4-vinylpyridine-co-divinylbenzene) supported cobalt and chromium complexes
(Elsevier Science Sa, Lausanne, 2010)
Polymer supported catalysts with Co(II) and Cr(VI) ions were prepared and characterized by means of FTIR, diffuse reflectance UV-vis, nitrogen physisorption, mercury porosimetry and SEM-EDX measurements. The catalytic ...
Purification and characterisation of Saccharomyces cerevisiae external invertase isoforms
(Elsevier Sci Ltd, Oxford, 2010)
Four external invertase isoforms (EINV1, EINV2, EINV3 and EINV4) from Saccharomyces cerevisiae were highly purified by isoelectric precipitation, ethanol precipitation, ion-exchange on QAE-Sephadex and gel filtration using ...
Evaluation of the thermal stability and digestibility of heterologously produced banana lectin
(Elsevier Sci Ltd, Oxford, 2010)
The thermal stability of recombinant mannose-specific banana lectin (rBanLec), as well as its stability under conditions of simulated gastro-intestinal fluid (SGF), was investigated. rBanLec was heterologously produced in ...
Allosteric regulation of the conformational dynamics of a cavitand receptor
(Amer Chemical Soc, Washington, 2006)
Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative H-1 NMR studies have revealed that the rate of the conformational isomerization of 1 can ...
Avarol-induced DNA strand breakage in vitro and in Friend erythroleukemia cells
(Cancer Research, 1987)
The hydroquinone-containing cytostatic compound avarol inhibits predominantly growth of those cell lines which have a low level of superoxide dismutase. The substrate of this enzyme, the superoxide anion, was found to be ...
Detection and quantification of leucyl arninopeptidase after native electrophoresis using leucine-p-nitroanilide
(Wiley-V C H Verlag Gmbh, Weinheim, 2005)
A general method for detecting leucyl aminopeptidase activity after native polyacrylamide gel electrophoresis (PAGE) in situ is described. The method is based on diazotization of p-nitroaniline, liberated in the polyacrylamide ...
Characterisation of Serbian unifloral honeys according to their physicochemical parameters
(Elsevier Sci Ltd, Oxford, 2012)
The characterisation of three unifloral Serbian honeys (acacia, sunflower and linden) was carried out based on some common physicochemical parameters (water content, electrical conductivity, free acidity, optical rotation ...
Crystallographic and ab Initio Study of Pyridine Stacking Interactions. Local Nature of Hydrogen Bond Effect in Stacking Interactions
(Amer Chemical Soc, Washington, 2012)
Stacking interactions between pyridine molecules and the influence of simultaneous hydrogen bonds were studied by analyzing data in the Cambridge Structural Database (CSD) and by ab initio calculations. The results show ...