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dc.creatorNovaković, Miroslav M.
dc.creatorBukvicki, Danka
dc.creatorVajs, Vlatka
dc.creatorTešević, Vele
dc.creatorMilosavljević, Slobodan M.
dc.creatorMarin, Petar D.
dc.creatorAsakawa, Yoshinori
dc.date.accessioned2018-11-22T00:44:14Z
dc.date.available2018-11-22T00:44:14Z
dc.date.issued2018
dc.identifier.issn1934-578X
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/2150
dc.description.abstractA number of potentially useful compounds with various biological activities can be obtained from plant metabolites by microorganisms. In present research, essential oil of Calamintha glandulosa was subjected to the biotransformation process by mycromicete Aspergillus niger. GC/MS analyses of the original and biotransformed essential oil have revealed six(1-6) biotransformed compounds from one of the main component-limonene and one biotransformed product (7) originating from the less abundant component-thymol. Piperitone epoxide and piperitenone epoxide, the most abundant components of the original oil, were not biotransformed but gave three artefacts (A1, A2, B1) due to the acidic conditions formed in A. niger medium. Compounds 5, 6 as well as 7 have not been previously found as a biotransformation products of limonene (5 and 6) and thymol (7), respectively. New products (5, 6, and 7) together with the artefacts, were isolated by silica gel column chromatography followed by preparative silica gel thin layer chromatography, and their structures were established by a combination of 1D and 2D NMR spectra and GC/MS data. Biotransformation has one more confirmed as useful method, complementary to synthesis, for obtaining different type of molecules.en
dc.publisherNatural Products Inc, Westerville
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173029/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.relationMatsumae International Foundation
dc.rightsrestrictedAccess
dc.sourceNatural Product Communications
dc.subjectCalamintha glandulosaen
dc.subjectEssential oilen
dc.subjectBiotransformationen
dc.subjectAspergillus niger.en
dc.titleMicrobial Transformation of Calamintha glandulosa Essential Oil by Aspergillus nigeren
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМилосављевиц, Слободан; Буквицки, Данка; Тешевић, Веле; Aсакаwа, Yосхинори; Вајс, Влатка; Новаковиц, Мирослав; Марин, Петар;
dc.citation.volume13
dc.citation.issue4
dc.citation.spage479
dc.citation.epage482
dc.identifier.wos000433651900025
dc.citation.other13(4): 479-482
dc.citation.rankM23
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85048122670
dc.identifier.rcubKon_3481


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