The advent of gold catalysis has transformed hydroxyalkoxylation of alkynes - once a rudimentary, mercury(II)-, or silver(I)-catalyzed process limited to structurally simple substrates - into a sophisticated method that has found application in syntheses of highly complex organic molecules. This transformation can further be combined with carbon-carbon bond-forming reactions into domino sequences that allow for a considerable increase of molecular complexity within a single synthetic step. Some recent examples of the development and synthetic applications of these reactions are provided.
Keywords:
domino reactions / gold catalysis / total synthesis
TY - JOUR
AU - Bihelović, Filip
AU - Vulović, Bojan
AU - Saičić, Radomir
PY - 2018
UR - http://cherry.chem.bg.ac.rs/handle/123456789/2156
AB - The advent of gold catalysis has transformed hydroxyalkoxylation of alkynes - once a rudimentary, mercury(II)-, or silver(I)-catalyzed process limited to structurally simple substrates - into a sophisticated method that has found application in syntheses of highly complex organic molecules. This transformation can further be combined with carbon-carbon bond-forming reactions into domino sequences that allow for a considerable increase of molecular complexity within a single synthetic step. Some recent examples of the development and synthetic applications of these reactions are provided.
PB - Wiley-V C H Verlag Gmbh, Weinheim
T2 - Israel Journal of Chemistry
T1 - Gold(I)-Catalyzed C-O/C-C Bond-Forming Domino Reactions and Their Synthetic Applications
VL - 58
IS - 5
SP - 521
EP - 530
DO - 10.1002/ijch.201700033
ER -
@article{
author = "Bihelović, Filip and Vulović, Bojan and Saičić, Radomir",
year = "2018",
url = "http://cherry.chem.bg.ac.rs/handle/123456789/2156",
abstract = "The advent of gold catalysis has transformed hydroxyalkoxylation of alkynes - once a rudimentary, mercury(II)-, or silver(I)-catalyzed process limited to structurally simple substrates - into a sophisticated method that has found application in syntheses of highly complex organic molecules. This transformation can further be combined with carbon-carbon bond-forming reactions into domino sequences that allow for a considerable increase of molecular complexity within a single synthetic step. Some recent examples of the development and synthetic applications of these reactions are provided.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Israel Journal of Chemistry",
title = "Gold(I)-Catalyzed C-O/C-C Bond-Forming Domino Reactions and Their Synthetic Applications",
volume = "58",
number = "5",
pages = "521-530",
doi = "10.1002/ijch.201700033"
}
Bihelović, F., Vulović, B.,& Saičić, R. (2018). Gold(I)-Catalyzed C-O/C-C Bond-Forming Domino Reactions and Their Synthetic Applications.
Israel Journal of Chemistry
Wiley-V C H Verlag Gmbh, Weinheim., 58(5), 521-530.
https://doi.org/10.1002/ijch.201700033
Bihelović F, Vulović B, Saičić R. Gold(I)-Catalyzed C-O/C-C Bond-Forming Domino Reactions and Their Synthetic Applications. Israel Journal of Chemistry. 2018;58(5):521-530
Bihelović Filip, Vulović Bojan, Saičić Radomir, "Gold(I)-Catalyzed C-O/C-C Bond-Forming Domino Reactions and Their Synthetic Applications" Israel Journal of Chemistry, 58, no. 5 (2018):521-530,
https://doi.org/10.1002/ijch.201700033 .
