Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
Samo za registrovane korisnike
2016
Autori
Mileski, Ksenija S.Ćirić, Ana D.
Trifunović, Snežana S.
Ristić, Mihailo S.
Soković, Marina
Matevski, Vlado S.
Tešević, Vele
Jadranin, Milka
Marin, Petar D.
Džamić, Ana M.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radica...ls and various pathogenic strains, including the wild type of P. aeruginosa.
Izvor:
Food and Function, 2016, 7, 9, 4061-4074Izdavač:
- Royal Soc Chemistry, Cambridge
Finansiranje / projekti:
- Mikromorfološka, fitohemijska i molekularna istraživanja biljaka - sistematski, ekološki i primenljivi aspekti (RS-MESTD-Basic Research (BR or ON)-173029)
- Karakterizacija i primena metabolita gljiva i utvrđivanje potencijala novih biofungicida (RS-MESTD-Basic Research (BR or ON)-173032)
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-MESTD-Basic Research (BR or ON)-172053)
Napomena:
- Peer-reviewed manuscript: http://cherry.chem.bg.ac.rs/handle/123456789/3521
DOI: 10.1039/c6fo01018k
ISSN: 2042-6496
PubMed: 27713984
WoS: 000384254100041
Scopus: 2-s2.0-84987888552
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Mileski, Ksenija S. AU - Ćirić, Ana D. AU - Trifunović, Snežana S. AU - Ristić, Mihailo S. AU - Soković, Marina AU - Matevski, Vlado S. AU - Tešević, Vele AU - Jadranin, Milka AU - Marin, Petar D. AU - Džamić, Ana M. PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2316 AB - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa. PB - Royal Soc Chemistry, Cambridge T2 - Food and Function T1 - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1 VL - 7 IS - 9 SP - 4061 EP - 4074 DO - 10.1039/c6fo01018k ER -
@article{ author = "Mileski, Ksenija S. and Ćirić, Ana D. and Trifunović, Snežana S. and Ristić, Mihailo S. and Soković, Marina and Matevski, Vlado S. and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Džamić, Ana M.", year = "2016", abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.", publisher = "Royal Soc Chemistry, Cambridge", journal = "Food and Function", title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1", volume = "7", number = "9", pages = "4061-4074", doi = "10.1039/c6fo01018k" }
Mileski, K. S., Ćirić, A. D., Trifunović, S. S., Ristić, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Džamić, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function Royal Soc Chemistry, Cambridge., 7(9), 4061-4074. https://doi.org/10.1039/c6fo01018k
Mileski KS, Ćirić AD, Trifunović SS, Ristić MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Džamić AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function. 2016;7(9):4061-4074. doi:10.1039/c6fo01018k .
Mileski, Ksenija S., Ćirić, Ana D., Trifunović, Snežana S., Ristić, Mihailo S., Soković, Marina, Matevski, Vlado S., Tešević, Vele, Jadranin, Milka, Marin, Petar D., Džamić, Ana M., "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food and Function, 7, no. 9 (2016):4061-4074, https://doi.org/10.1039/c6fo01018k . .