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dc.creatorMihajlović-Lalić, Ljiljana
dc.creatorDamjanovic, Ljiljana
dc.creatorŠumar-Ristović, Maja
dc.creatorSavić, Aleksandar
dc.creatorSabo, Tibor
dc.creatorDondur, Vera
dc.creatorGrgurić-Šipka, Sanja
dc.date.accessioned2018-11-22T00:37:01Z
dc.date.available2018-11-22T00:37:01Z
dc.date.issued2016
dc.identifier.issn0352-5139
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/2325
dc.description.abstractThe thermal behaviour of a Pt(IV) and a Ru(II) complex coordinated to dibutyl (S,S)-alpha,alpha'-(1,2-ethanediyldiimino)biscyclohexanepropanoate was investigated using thermogravimetry (TG) and differential scanning calorimetry (DSC). The study included an investigation of the thermal decomposition of these complexes in the temperature range of 30 to 590 degrees C and an evaluation of the activation energy for the first decomposition steps. For both metal complexes, broad DSC peaks indicated complex thermal transformation processes. The two-step decomposition of the Pt(IV) complex started at 175 and ended at about 418 degrees C, leaving elemental platinum as the final residue. On the other hand, the Ru(II) analogue decomposed in three stages. Thermal degradation was evident beginning at 144 degrees C and suggested the decomposition of a coordinated ligand as the dominant process. For this complex, the proposed final residue was RuO2. Kinetic parameters for the first decomposition step were obtained by means of the multi-heating rates method, in this case the Kissinger-Akahira-Sunose (KAS) method. The mean activation energy calculated for 0.2 lt alpha lt 0.8 were 122.0 kJ mol(-1) for the Pt(IV) and 118.9 kJ mol(-1) for the Ru(II) complex and decreased constantly, a characteristic of a multi-step process.en
dc.publisherSerbian Chemical Soc, Belgrade
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172035/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172055/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172018/RS//
dc.rightsopenAccess
dc.sourceJournal of the Serbian Chemical Society
dc.subjectplatinum (IV) complexen
dc.subjectruthenium (II) complexen
dc.subjectanti-tumor activityen
dc.subjectactivation energyen
dc.subjectTG-DSCen
dc.titleCytotoxic Pt(IV) and Ru(II) complexes containing a biologically relevant edda-type ligand: A comparative study of their thermal propertiesen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractГргурић-Шипка, Сања; Сабо, Тибор; Дондур, Вера; Дамјановиц, Љиљана; Савић, Aлександар; Шумар-Ристовић, Маја; Михајловић-Лалић, Љиљана;
dc.citation.volume81
dc.citation.issue8
dc.citation.spage897
dc.citation.epage905
dc.identifier.wos000384930600005
dc.identifier.doi10.2298/JSC160320059M
dc.citation.other81(8): 897-905
dc.citation.rankM23
dc.description.otherSupplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3434]
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-84987810051
dc.identifier.fulltexthttp://cherry.chem.bg.ac.rs/bitstream/id/9308/2323.pdf
dc.identifier.rcubKon_3141


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