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A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)

dc.creatorMarjanović-Trajković, Jasna
dc.creatorFerjančić, Zorana
dc.creatorSaičić, Radomir
dc.date.accessioned2018-11-22T00:40:00Z
dc.date.available2018-11-22T00:40:00Z
dc.date.issued2017
dc.identifier.issn0040-4020
dc.identifier.urihttps://cherry.chem.bg.ac.rs/handle/123456789/2452
dc.description.abstractA catalytic asymmetric synthesis of (+)-aza-galacto-fagomine (AGF) - the most promising compound for the pharmacological chaperone therapy of Krabbe disease was accomplished in six steps, in 14% overall yield. The synthesis hinges on the combination of organocatalyzed aldolization and reductive hydrazination.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172027/RS//
dc.relationSerbian Academy of Sciences and Arts [F193]
dc.rightsrestrictedAccess
dc.sourceTetrahedron
dc.subjectAza-galactofagomineen
dc.subjectOrganocatalysisen
dc.subjectKrabbe diseaseen
dc.subjectEnantioselective synthesisen
dc.subjectAzasugarsen
dc.titleA short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМарјановић-Трајковић, Јасна; Ферјанчић, Зорана; Саичић, Радомир;
dc.citation.volume73
dc.citation.issue18
dc.citation.spage2630
dc.identifier.wos000400226000006
dc.identifier.doi10.1016/j.tet.2017.03.052
dc.citation.other73(18): 2630-2632
dc.citation.rankM22
dc.description.otherPeer-reviewed manuscript: [http://cherry.chem.bg.ac.rs/handle/123456789/3025]
dc.description.otherSupplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3026]
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-85016011635


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