Heck-Like Reactions Involving Heteroatomic Electrophiles
Abstract
Since the discovery of the Heck reaction in the early seventies, the reaction has become a powerful tool in synthetic organic chemistry. By employing heteroatomic instead of traditional carbon electrophiles, the Heck reaction shows an intriguing flexibility. These hetereoatomic Heck reactions reinvigorate the area, by offering new routes to highly useful synthetic precursors and structural motifs present in biologically active compounds. This microreview focuses on early developments leading to the heteroatomic-Heck reactions (silyl-Heck, boryl-Heck and intramolecular aza-Heck), current state of the emerging area, as well as that of a few related processes.
Keywords:
Heck reaction / Homogeneous catalysis / Synthetic methods / PalladiumSource:
European Journal of Organic Chemistry, 2017, 34, 4996-5009Publisher:
- Wiley-V C H Verlag Gmbh, Weinheim
Funding / projects:
- Research Corporation Cottrell Scholars Program
- University of Delaware
- Delaware Economic Development Office [16A00384]
- National Science Foundation [CAREER CHE-1254360]
- National Institute of General Medical Science [P20GM104316]
DOI: 10.1002/ejoc.201700485
ISSN: 1434-193X
PubMed: 29104453
WoS: 000410792200002
Scopus: 2-s2.0-85021826631
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Vulović, Bojan AU - Watson, Donald A. PY - 2017 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2525 AB - Since the discovery of the Heck reaction in the early seventies, the reaction has become a powerful tool in synthetic organic chemistry. By employing heteroatomic instead of traditional carbon electrophiles, the Heck reaction shows an intriguing flexibility. These hetereoatomic Heck reactions reinvigorate the area, by offering new routes to highly useful synthetic precursors and structural motifs present in biologically active compounds. This microreview focuses on early developments leading to the heteroatomic-Heck reactions (silyl-Heck, boryl-Heck and intramolecular aza-Heck), current state of the emerging area, as well as that of a few related processes. PB - Wiley-V C H Verlag Gmbh, Weinheim T2 - European Journal of Organic Chemistry T1 - Heck-Like Reactions Involving Heteroatomic Electrophiles IS - 34 SP - 4996 EP - 5009 DO - 10.1002/ejoc.201700485 ER -
@article{ author = "Vulović, Bojan and Watson, Donald A.", year = "2017", abstract = "Since the discovery of the Heck reaction in the early seventies, the reaction has become a powerful tool in synthetic organic chemistry. By employing heteroatomic instead of traditional carbon electrophiles, the Heck reaction shows an intriguing flexibility. These hetereoatomic Heck reactions reinvigorate the area, by offering new routes to highly useful synthetic precursors and structural motifs present in biologically active compounds. This microreview focuses on early developments leading to the heteroatomic-Heck reactions (silyl-Heck, boryl-Heck and intramolecular aza-Heck), current state of the emerging area, as well as that of a few related processes.", publisher = "Wiley-V C H Verlag Gmbh, Weinheim", journal = "European Journal of Organic Chemistry", title = "Heck-Like Reactions Involving Heteroatomic Electrophiles", number = "34", pages = "4996-5009", doi = "10.1002/ejoc.201700485" }
Vulović, B.,& Watson, D. A.. (2017). Heck-Like Reactions Involving Heteroatomic Electrophiles. in European Journal of Organic Chemistry Wiley-V C H Verlag Gmbh, Weinheim.(34), 4996-5009. https://doi.org/10.1002/ejoc.201700485
Vulović B, Watson DA. Heck-Like Reactions Involving Heteroatomic Electrophiles. in European Journal of Organic Chemistry. 2017;(34):4996-5009. doi:10.1002/ejoc.201700485 .
Vulović, Bojan, Watson, Donald A., "Heck-Like Reactions Involving Heteroatomic Electrophiles" in European Journal of Organic Chemistry, no. 34 (2017):4996-5009, https://doi.org/10.1002/ejoc.201700485 . .