Oxidative stress parameters in two Pelophylax esculentus complex frogs during pre- and post-hibernation: Arousal vs heavy metals
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2017
Authors
Prokić, Marko D.Borković-Mitić, Slavica S.
Krizmanić, Imre I.
Mutić, Jelena
Gavrić, Jelena P.
Despotović, Svetlana G.
Gavrilović, Branka R.
Radovanović, Tijana B.
Pavlović, Slađan Z.
Saičić, Zorica S.
Article (Published version)
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In spring, frogs from temperate regions are faced with arousal-induced oxidative stress and exposure to various xenobiotics from the environment. The question is whether pollutants can significantly modify the antioxidative defense system (AOS) response of hibernators during recovery from hibernation. If this assumption is true, we would then expect different patterns of seasonal variations in the AOS between individuals exposed to different levels of pollution. To examine this assumption, we determined the relationship between seasonal variations of accumulated metals and AOS parameters in the skin and muscle of two frog species from the Pelophylax esculentus complex (P. ridibundus and P. esculentus) inhabiting two localities (the Danube-Tisza-Danube canal and the Ponjavica River) with different levels of pollution during pre- and post-hibernation periods, respectively autumn and spring. Our results showed that even though there were differences in the concentrations of accumulated me...tals and AOS parameters between localities and species, the frogs displayed almost the same patterns of AOS variations during seasons, with a higher AOS response observed in spring. The parameters SH groups, GSH, GR and SOD had been contributed most rather than others. Our findings indicate that oxidative stress during the post-hibernation period was mainly caused by the organisms' recovery from hibernation, as the result of natural selection acting on the AOS, and that the accumulated metals did not significantly, modify the AOS response. The present study provides new insight into the biological and physiological cellular responses of frogs to arousal stress.
Keywords:
Antioxidative defense system / Arousal / Frogs / Heavy metals / Oxidative stress / Pelophylax esculentus / Pelophylax ridibundusSource:
Comparative Biochemistry and Physiology. C: Toxicology and Pharmacology, 2017, 202, 19-25Publisher:
- Elsevier Science Inc, New York
Funding / projects:
- Molecular and physiological biomonitoring of aerobic organisms based on the determination of biochemical biomarkers of oxidative stress (RS-MESTD-Basic Research (BR or ON)-173041)
Note:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/2962
DOI: 10.1016/j.cbpc.2017.07.006
ISSN: 1532-0456
PubMed: 28757213
WoS: 000414815500003
Scopus: 2-s2.0-85026440581
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Prokić, Marko D. AU - Borković-Mitić, Slavica S. AU - Krizmanić, Imre I. AU - Mutić, Jelena AU - Gavrić, Jelena P. AU - Despotović, Svetlana G. AU - Gavrilović, Branka R. AU - Radovanović, Tijana B. AU - Pavlović, Slađan Z. AU - Saičić, Zorica S. PY - 2017 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2548 AB - In spring, frogs from temperate regions are faced with arousal-induced oxidative stress and exposure to various xenobiotics from the environment. The question is whether pollutants can significantly modify the antioxidative defense system (AOS) response of hibernators during recovery from hibernation. If this assumption is true, we would then expect different patterns of seasonal variations in the AOS between individuals exposed to different levels of pollution. To examine this assumption, we determined the relationship between seasonal variations of accumulated metals and AOS parameters in the skin and muscle of two frog species from the Pelophylax esculentus complex (P. ridibundus and P. esculentus) inhabiting two localities (the Danube-Tisza-Danube canal and the Ponjavica River) with different levels of pollution during pre- and post-hibernation periods, respectively autumn and spring. Our results showed that even though there were differences in the concentrations of accumulated metals and AOS parameters between localities and species, the frogs displayed almost the same patterns of AOS variations during seasons, with a higher AOS response observed in spring. The parameters SH groups, GSH, GR and SOD had been contributed most rather than others. Our findings indicate that oxidative stress during the post-hibernation period was mainly caused by the organisms' recovery from hibernation, as the result of natural selection acting on the AOS, and that the accumulated metals did not significantly, modify the AOS response. The present study provides new insight into the biological and physiological cellular responses of frogs to arousal stress. PB - Elsevier Science Inc, New York T2 - Comparative Biochemistry and Physiology. C: Toxicology and Pharmacology T1 - Oxidative stress parameters in two Pelophylax esculentus complex frogs during pre- and post-hibernation: Arousal vs heavy metals VL - 202 SP - 19 EP - 25 DO - 10.1016/j.cbpc.2017.07.006 ER -
@article{ author = "Prokić, Marko D. and Borković-Mitić, Slavica S. and Krizmanić, Imre I. and Mutić, Jelena and Gavrić, Jelena P. and Despotović, Svetlana G. and Gavrilović, Branka R. and Radovanović, Tijana B. and Pavlović, Slađan Z. and Saičić, Zorica S.", year = "2017", abstract = "In spring, frogs from temperate regions are faced with arousal-induced oxidative stress and exposure to various xenobiotics from the environment. The question is whether pollutants can significantly modify the antioxidative defense system (AOS) response of hibernators during recovery from hibernation. If this assumption is true, we would then expect different patterns of seasonal variations in the AOS between individuals exposed to different levels of pollution. To examine this assumption, we determined the relationship between seasonal variations of accumulated metals and AOS parameters in the skin and muscle of two frog species from the Pelophylax esculentus complex (P. ridibundus and P. esculentus) inhabiting two localities (the Danube-Tisza-Danube canal and the Ponjavica River) with different levels of pollution during pre- and post-hibernation periods, respectively autumn and spring. Our results showed that even though there were differences in the concentrations of accumulated metals and AOS parameters between localities and species, the frogs displayed almost the same patterns of AOS variations during seasons, with a higher AOS response observed in spring. The parameters SH groups, GSH, GR and SOD had been contributed most rather than others. Our findings indicate that oxidative stress during the post-hibernation period was mainly caused by the organisms' recovery from hibernation, as the result of natural selection acting on the AOS, and that the accumulated metals did not significantly, modify the AOS response. The present study provides new insight into the biological and physiological cellular responses of frogs to arousal stress.", publisher = "Elsevier Science Inc, New York", journal = "Comparative Biochemistry and Physiology. C: Toxicology and Pharmacology", title = "Oxidative stress parameters in two Pelophylax esculentus complex frogs during pre- and post-hibernation: Arousal vs heavy metals", volume = "202", pages = "19-25", doi = "10.1016/j.cbpc.2017.07.006" }
Prokić, M. D., Borković-Mitić, S. S., Krizmanić, I. I., Mutić, J., Gavrić, J. P., Despotović, S. G., Gavrilović, B. R., Radovanović, T. B., Pavlović, S. Z.,& Saičić, Z. S.. (2017). Oxidative stress parameters in two Pelophylax esculentus complex frogs during pre- and post-hibernation: Arousal vs heavy metals. in Comparative Biochemistry and Physiology. C: Toxicology and Pharmacology Elsevier Science Inc, New York., 202, 19-25. https://doi.org/10.1016/j.cbpc.2017.07.006
Prokić MD, Borković-Mitić SS, Krizmanić II, Mutić J, Gavrić JP, Despotović SG, Gavrilović BR, Radovanović TB, Pavlović SZ, Saičić ZS. Oxidative stress parameters in two Pelophylax esculentus complex frogs during pre- and post-hibernation: Arousal vs heavy metals. in Comparative Biochemistry and Physiology. C: Toxicology and Pharmacology. 2017;202:19-25. doi:10.1016/j.cbpc.2017.07.006 .
Prokić, Marko D., Borković-Mitić, Slavica S., Krizmanić, Imre I., Mutić, Jelena, Gavrić, Jelena P., Despotović, Svetlana G., Gavrilović, Branka R., Radovanović, Tijana B., Pavlović, Slađan Z., Saičić, Zorica S., "Oxidative stress parameters in two Pelophylax esculentus complex frogs during pre- and post-hibernation: Arousal vs heavy metals" in Comparative Biochemistry and Physiology. C: Toxicology and Pharmacology, 202 (2017):19-25, https://doi.org/10.1016/j.cbpc.2017.07.006 . .