One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling
Аутори
Dinić, IvanaVuković, Marina
Mančić, Lidija
Krmpot, Aleksandar J.
Milošević, Olivera B.
Остала ауторства
Uskoković, Dragan P.Radmilović, Velimir R.
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the p...articles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.
Кључне речи:
up-converting nanoparticles / NaYF4:Yb,Er / cell labelling / nanoparticlesИзвор:
Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018, 2018, 116-116Издавач:
- Belgrade : Materials Research Society of Serbia
Финансирање / пројекти:
- Рационални дизајн и синтеза биолошки активних и координационих једињења и функционалних материјала, релевантних у (био)нанотехнологији (RS-MESTD-Basic Research (BR or ON)-172035)
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - CONF AU - Dinić, Ivana AU - Vuković, Marina AU - Mančić, Lidija AU - Krmpot, Aleksandar J. AU - Milošević, Olivera B. PY - 2018 UR - http://dais.sanu.ac.rs/123456789/3635 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2774 AB - In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the particles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source. PB - Belgrade : Materials Research Society of Serbia C3 - Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018 T1 - One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling SP - 116 EP - 116 UR - https://hdl.handle.net/21.15107/rcub_cherry_2774 ER -
@conference{ author = "Dinić, Ivana and Vuković, Marina and Mančić, Lidija and Krmpot, Aleksandar J. and Milošević, Olivera B.", year = "2018", abstract = "In modern medical research, great attention has been focused to the development of the new biomarkers which include up-converting nanoparticles (UCNPs). Their optical response is triggered by NIR radiation that achieves deeper tissue penetration when compared with traditionally used fluorophores. In this work, biocompatible NaYF4: Yb, Er nanoparticles were synthesized by polymer assisted one-pot solvothermal processing using chitosan or poly(lacticco- glycolic acid). X-ray powder diffraction and electron microscopy results revealed differences in crystal arrangement and morphology of the as-synthesized particles. Fourier transform infrared spectroscopy confirmed the presence of corresponding polymers moiety on UCNPs surface providing their biocompatibility and low cytotoxicity towards human gingival fibroblasts (HFG). As a consequence of efficient up-conversion, prominent green emission (between 512-533nm and between 533-560nm) as well as red emission (630-690nm) were recorded in the particles photoluminescence spectra, and these are applied further in the visualization of the HFG using the laser scanning microscopy with a NIR laser source.", publisher = "Belgrade : Materials Research Society of Serbia", journal = "Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018", title = "One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling", pages = "116-116", url = "https://hdl.handle.net/21.15107/rcub_cherry_2774" }
Dinić, I., Vuković, M., Mančić, L., Krmpot, A. J.,& Milošević, O. B.. (2018). One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling. in Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018 Belgrade : Materials Research Society of Serbia., 116-116. https://hdl.handle.net/21.15107/rcub_cherry_2774
Dinić I, Vuković M, Mančić L, Krmpot AJ, Milošević OB. One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling. in Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018. 2018;:116-116. https://hdl.handle.net/21.15107/rcub_cherry_2774 .
Dinić, Ivana, Vuković, Marina, Mančić, Lidija, Krmpot, Aleksandar J., Milošević, Olivera B., "One-pot synthesis of biocompatible NaYF4:Yb,Er nanoparticles for cell labeling" in Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018 (2018):116-116, https://hdl.handle.net/21.15107/rcub_cherry_2774 .