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Quinoline based mono- and bis-(thio) carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models
(Royal Soc Chemistry, Cambridge, 2016)
A comparative study of antitumor activity of mono- and bis-quinoline based (thio) carbohydrazones was investigated by a series of tests on two human malignant cell lines: acute monocytic leukemia (THP-1) and pancreatic ...
Synthesis of endoperoxides by domino reactions of ketones and molecular oxygen
(Royal Soc Chemistry, Cambridge, 2015)
Domino reactions of ketones with molecular oxygen in the presence of potassium hydroxide and potassium t-butoxide afford cyclic hydroperoxy acetals (3,5-dihydroxy-1,2-dioxanes). Mixed endoperoxides can also be obtained in ...
Fulleropyrrolidine molecular dumbbells act as multi-electron-acceptor triads. Spectroscopic, electrochemical, computational and morphological characterizations
(Royal Soc Chemistry, Cambridge, 2015)
We synthesized three dumbbell-like compounds 2a-c, each containing two C-60 groups at the periphery and pyromellitic diimide (PMDI) in the middle, and examined their electronic as well as assembly characteristics with both ...
Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine
(Royal Soc Chemistry, Cambridge, 2015)
A simple and efficient procedure is described for electrochemical determination of trifluoperazine (TFP), a prominent compound in a large group of phenothiazine derivatives with potent physiological activity. This method ...
Elemental composition as a tool for the assessment of type, seasonal variability, and geographical origin of wine and its contribution to daily elemental intake
(Royal Soc Chemistry, Cambridge, 2017)
The elemental profiles of 63 red and white wine samples from four different regions in Serbia were investigated. Twenty-one elements were analysed (Ca, Mg, Na, K, Fe, Mn, Cu, Zn, Co, Se, Cr, V, Ni, Cd, As, Al, Sb, Pb, Ba, ...
Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction
(Royal Soc Chemistry, Cambridge, 2015)
A new Zn(II)-based potential chemotherapeutic agent was synthesized from the ligand 2-quinolinecarboxaldehyde selenosemicarbazone (Hqasesc). Single crystal X-ray diffraction analysis showed that the Zn(II) complex consists ...
Synthesis of gamma-nitroaldehydes containing quaternary carbon in the alpha-position using a 4-oxalocrotonate tautomerase whole-cell biocatalyst
(Royal Soc Chemistry, Cambridge, 2014)
Synthesis of gamma-nitroaldehydes from branched chain aldehydes and a range of alpha,beta-unsaturated nitroalkenes was achieved by a whole-cell biocatalytic reaction using 4-oxalocrotonate tautomerase as catalyst. Under ...
Assessment of the interacting mechanism between Candida rugosa lipases and hydroxyapatite and identification of the hydroxyapatite-binding sequence through proteomics and molecular modelling
(Royal Soc Chemistry, Cambridge, 2016)
Hydroxyapatite (HAP), a calcium-phosphate bioactive ceramic, is actively employed in medical and separation sciences. Although different classes of biomacromolecules interact with this material, interactions with proteins ...
Copper(II) complexes with aromatic nitrogen-containing heterocycles as effective inhibitors of quorum sensing activity in Pseudomonas aeruginosa
(Royal Soc Chemistry, Cambridge, 2016)
Five copper(II) complexes 1-5 with aromatic nitrogen-containing heterocycles, pyrimidine (pm, 1), pyrazine (pz, 2), quinazoline (qz, 3 and 4) and phthalazine (phtz, 5) have been synthesized and structurally characterized ...
A comparative antimicrobial and toxicological study of gold(III) and silver(I) complexes with aromatic nitrogen-containing heterocycles: synergistic activity and improved selectivity index of Au(III)/Ag(I) complexes mixture
(Royal Soc Chemistry, Cambridge, 2016)
Five aromatic nitrogen-containing heterocycles, pyridazine (pydz, 1), pyrimidine (pm, 2), pyrazine (pz, 3), quinoxaline (qx, 4) and phenazine (phz, 5) have been used for the synthesis of gold(III) and silver(I) complexes. ...