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Novel methylene modified cyclohexyl ethylenediamine-N,N '-diacetate ligands and their platinum(IV) complexes. Influence on biological activity
(Elsevier Science Inc, New York, 2012)
This paper focuses on the synthesis, characterization and biological activity of new N,N'-methylene modified cyclohexyl ethylenediamine-N,N'-diacetate (edda)-type ligands and their Pt(IV) complexes. Both the ligands and ...
The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate
(Elsevier Sci Ltd, Oxford, 2013)
The biodegradable polymer medium chain length polyhydroxyalkanoate (mclPHA), produced by Pseudomonas putida CA-3, was depolymerised and the predominant monomer (R)-3-hydroxydecanoic acid (R10) purified. R10 was conjugated ...
A Comparative Study of In Vitro Cytotoxic, Antioxidant, and Antimicrobial Activity of Pt( II), Zn( II), Cu( II), and Co( III) Complexes with N-heteroaromatic Schiff Base ( E)-2-[ N-( 1-pyridin-2-yl-ethylidene) hydrazino] acetate
(Wiley, Hoboken, 2014)
In search for novel biologically active metal based compounds, an evaluation of in vitro cytotoxic, antioxidant, and antimicrobial activity of new Pt(II) complex and its Zn(II), Cu(II), and Co(III) analogues, with NNO ...
Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide
(Elsevier Science Inc, New York, 2011)
A novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide, N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide was synthesized and characterized by elemental ...
Synthesis, characterization and ROS-mediated cytotoxic action of novel (S, S)-1,3-propanediamine-N,N '-di-2-(3-cyclohexyl)propanoic acid and corresponding esters
(Academic Press Inc Elsevier Science, San Diego, 2014)
This study involves the synthesis and characterization of novel cyclohexyl 1,3-propanediamine-N, N'-diacetate molecules as well as investigation of their cytotoxic action. New acid 1a was synthesized by reaction between ...
Synthesis and biological activity of amino acid derivatives of avarone and its model compound
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
A series of eighteen derivatives of marine sesquiterpene quinone avarone and its model system tert-butylquinone with amino acids has been synthesized by nucleophilic addition of amino acids to the quinones. In vitro cytotoxic ...
Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N '-diacetate
(Elsevier Science Inc, New York, 2013)
Six novel gold(III) complexes containing O,O'-dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate ([AuCl2{(S,S)-R(2)eddch}]PF6, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am; 1-6, respectively) were synthesized and ...
Simple avarone mimetics as selective agents against multidrug resistant cancer cells
(Elsevier France-Editions Scientifiques Medicales Elsevier, Paris, 2016)
In this work, synthesis of alkylamino and aralkylamino derivatives of sesquiterpene quinone avarone and its model compound tert-butylquinone was described. For all obtained derivatives biological activity was studied. ...
Structural, Magnetic, DFT, and Biological Studies of Mononuclear and Dinuclear Cu-II Complexes with Bidentate N-Heteroaromatic Schiff Base Ligands
(Wiley-V C H Verlag Gmbh, Weinheim, 2015)
Copper(II) complexes with the condensation derivative of methyl hydrazinoacetate and 2-acetylpyridine were synthesized. The X-ray crystal structures for both complexes revealed that they are polymerized isomers. A common ...
Cytotoxic effect of Reseda lutea L.: A case of forgotten remedy
(Elsevier Ireland Ltd, Clare, 2014)
Ethnopharmacological relevance: Reseda lutea L (Resedaceae) or Wild Mignonette is a widely distributed plant species. Pliny the Elder (AD 23-AD 79), a Roman scholar and naturalist, reported the use of R. lutea for reducing ...