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A novel C,D-spirolactone analogue of paclitaxel: autophagy instead of apoptosis as a previously unknown mechanism of cytotoxic action for taxoids
(Royal Soc Chemistry, Cambridge, 2012)
The design, synthesis and biological evaluation of a novel C, D-spirolactone analogue of paclitaxel is described. This is the first paclitaxel analogue without an oxetane D-ring that shows a significant cytotoxic effect ...
Leaching of toxic elements from secondary alkaline lead slag and stabilized/solidified products
(Springer Japan, 2019)
Secondary alkaline lead slag (SALS), generated during lead–acid batteries recycling, is a hazardous waste due to its high reactivity, solubility, and migration of toxic elements. After pulverization caused by storage under ...
Influence of hydrogen bonds on edge-to-face interactions between pyridine molecules
(Springer, New York, 2018)
Edge-to-face interactions between two pyridine molecules and the influence of simultaneous hydrogen bonding of one or both of the pyridines to water on those interactions were studied by analyzing data from ab initio ...
Simultaneous Determination of Pb and Cd Traces in Water Samples by Anodic Stripping Voltammetry Using a Modified GC Electrode
(Wiley-Blackwell, Malden, 2011)
The determination of Pb and Cd with a Nafion-modified glassy carbon electrode and Cu-DPABA complex (Cu-DPABA NA/GCE; DPABA is methyl 3,5-bis{bis-[(pyridin-2-yl)methyl]amino}methyl-benzoate) as an alternative electrode for ...
In-depth quantitative profiling of post-translational modifications of Timothy grass pollen allergome in relation to environmental oxidative stress
(Elsevier, 2019)
An association between pollution (e.g., from traffic emissions) and the increased prevalence of respiratory allergies has been observed. Field-realistic exposure studies provide the most relevant assessment of the effects ...
Modulation of the specific immune response in Balb/cmice by intranasal application of recombinant H1D2 chimera
(Wiley, Hoboken, 2017)
BACKGROUND: Group 1 and group 2 allergens from house dust mite are the major elicitors of respiratory allergic diseases and the main candidates for immunotherapy. RESULTS: The potential therapeutic role of a chimera composed ...
Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity
(Elsevier, 2018)
An increase in the copper pool in body fluids has been related to a number of pathological conditions, including infections. Copper ions may affect antibiotics via the formation of coordination bonds and/or redox reactions. ...
Determination of pyridoxine (vitamin B-6) in pharmaceuticals and urine samples using unmodified boron-doped diamond electrode
(Elsevier Science Sa, Lausanne, 2016)
Pyridoxine (vitamin B-6, VB6) was detected in pharmaceutical preparation and human urine samples by employing differential pulse voltammetry (DPV) at unmodified boron doped electrode. In Britton-Robinson buffer solution ...
Antibacterial and antifungal properties of guanylhydrazones
(Serbian Chemical Soc, Belgrade, 2017)
A series of novel guanylhydrazones were designed, synthesized and characterized. All the compounds were screened for their antibacterial and antifungal activity. Compounds 26 and 27 showed excellent antibacterial activities ...
Synthesis of endoperoxides by domino reactions of ketones and molecular oxygen
(Royal Soc Chemistry, Cambridge, 2015)
Domino reactions of ketones with molecular oxygen in the presence of potassium hydroxide and potassium t-butoxide afford cyclic hydroperoxy acetals (3,5-dihydroxy-1,2-dioxanes). Mixed endoperoxides can also be obtained in ...