Bifunctional (Zn,Fe)3O4 nanoparticles: Tuning their efficiency for potential application in reagentless glucose biosensors and magnetic hyperthermia
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Dojčinović, Biljana P.
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In a new approach based on a two-step procedure, co-precipitation method followed by hydrothermal treatment in a microwave field, Zn-substituted Fe3O4 nanoparticles (ZnxFe3-xO4) were synthesized. Results of XRD, FT–IR and TEM analysis clearly demonstrate that nanoparticles were single phase, crystallizing in the spinel structure type (S.G. Fd3¯m) with crystallite size in the range of 2–20 nm, which strongly depends on Zn concentration. The produced nanoparticles were used for fabrication of modified carbon paste electrodes as a novel system for electrochemical non-enzymatic glucose detection. It was found that the increase of zinc concentration up to the value of x = 0.56 (Zn0.56Fe2.44O4) of as-prepared nanoparticles was followed with an increase of a performance of the modified carbon paste electrode toward glucose detection. Linear working range from 0.1 to 2 mM was obtained with detection limit of 0.03 mM, and with fast response time (<3 s). Proposed sensor was successfully appli...ed for the determination of glucose level in real samples with satisfactory recovery. The synthesized zinc-ferrite samples were also tested as potential heating agents in magnetic hyperthermia. The heating ability (SAR value) increases with x value, reaching maximum for x = 0.37. This is correlated with changes of particle size and magnetic characteristics which strongly depend on Zn concentration. © 2018 Elsevier B.V.
Keywords:Carbon electrodes / Glucose sensor / Hyperthermia / MW hydrothermal synthesis / Structural characterization
Source:Journal of Alloys and Compounds, 2019, 777, 454-462
- Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials (EU-621375)
- Ministry of Education, Science and Technological Development of the Republic of Serbia through the Eureka Project, E!9982
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/2953
- This is the peer-reviewed version of the following article: Ognjanović, M.; Stanković, D.; Ming, Y.; Zhang, H.; Jančar, B.; Dojčinović, B. P.; Prijović, Ž.; Antić, B. Bifunctional (Zn,Fe)3O4 Nanoparticles: Tuning Their Efficiency for Potential Application in Reagentless Glucose Biosensors and Magnetic Hyperthermia. Journal of Alloys and Compounds 2019, 777, 454–462. https://doi.org/10.1016/j.jallcom.2018.10.369