Synthesis, characterization and antimicrobial activity of the isothiocyanato Fe(III) Girard’s T hydrazone complex
Milenković, Milica R.
Radanović, Dušanka D.
Anđelković, Katarina K.
Article (Published version)
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The isothiocyanato Fe(III) complex with (E)-N,N,N-trimethyl-2-oxo--2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)ethan-1-aminium was synthesized and characterized by elemental analysis, IR spectroscopy and X-ray analysis. The octahedral geometry of the Fe(III) complex consists of the deprotonated form of the hydrazone ligand coordinated through the pyridine nitrogen, azomethine nitrogen and carbonyl oxygen atoms with three isothiocyanato ligands in the remaining coordination places. The measured effective magnetic moment for Fe(III) complex corresponds to high spin Fe(III) ion. The hydrazone ligand and its Fe(III) complex showed lower activity against the tested microbial strains than standard antimicrobial drugs.
Keywords:Hydrazone / Pseudohalides / X-ray structure, magnetic properties
Source:Journal of the Serbian Chemical Society, 2018, 83, 12, 1327-1337
- Interactions of natural products, their derivatives and coordination compounds with proteins and nucleic acids (RS-172055)
- Supplamantary material: http://cherry.chem.bg.ac.rs/handle/123456789/3307