Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet

Chen, Qiushui; Utech, Stefanie; Chen, Dong; Prodanović, Radivoje; Lin, Jin-Ming; Weitz, David A.

doi:10.1039/c6lc00231e

2016

nihms771767.pdf (700.3Kb)

Authors

Chen, Qiushui
Utech, Stefanie
Chen, Dong
Prodanović, Radivoje

Lin, Jin-Ming
Weitz, David A.

Article (Accepted Version)

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Abstract

This paper reports a droplet-based microfluidic approach to fabricate a large number of monodisperse, portable microtissues, each in an individual drop. We use water-water-oil double emulsions as templates and spatially assemble hepatocytes in the core and fibroblasts in the shell, forming a 3D liver model in a drop.

Source:
Lab on A Chip, 2016, 16, 8, 1346-1349

Publisher:

Royal Soc Chemistry, Cambridge

Funding / projects:

National Science Foundation [DMR-1310266]
China Equipment and Education Resources System [CERS-1-75]
Harvard Materials Research Science and Engineering Center [DMR-1420570]
National Institutes of Health [R01EB014703]
Deutsche Forschungsgemeinschaft
National Natural Science Foundation of China [214350002, 91213305, 81373373]

Note:

This is the peer-reviewed version of the following article: Chen, Qiushui, Utech, Stefanie, Chen, Dong, Prodanović, Radivoje, Lin, Jin-Ming, Weitz, David A., 2016. Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet. Lab on A Chip. 16, 1346-1349. https://doi.org/10.1039/c6lc00231e
Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3427

DOI: 10.1039/c6lc00231e

ISSN: 1473-0197

PubMed: 26999495

WoS: 000374224900006

Scopus: 2-s2.0-84964963468

[ Google Scholar ]



	116
	121

TY  - JOUR
AU  - Chen, Qiushui
AU  - Utech, Stefanie
AU  - Chen, Dong
AU  - Prodanović, Radivoje
AU  - Lin, Jin-Ming
AU  - Weitz, David A.
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2820
AB  - This paper reports a droplet-based microfluidic approach to fabricate a large number of monodisperse, portable microtissues, each in an individual drop. We use water-water-oil double emulsions as templates and spatially assemble hepatocytes in the core and fibroblasts in the shell, forming a 3D liver model in a drop.
PB  - Royal Soc Chemistry, Cambridge
T2  - Lab on A Chip
T1  - Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet
VL  - 16
IS  - 8
SP  - 1346
EP  - 1349
DO  - 10.1039/c6lc00231e
ER  -

@article{
author = "Chen, Qiushui and Utech, Stefanie and Chen, Dong and Prodanović, Radivoje and Lin, Jin-Ming and Weitz, David A.",
year = "2016",
abstract = "This paper reports a droplet-based microfluidic approach to fabricate a large number of monodisperse, portable microtissues, each in an individual drop. We use water-water-oil double emulsions as templates and spatially assemble hepatocytes in the core and fibroblasts in the shell, forming a 3D liver model in a drop.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Lab on A Chip",
title = "Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet",
volume = "16",
number = "8",
pages = "1346-1349",
doi = "10.1039/c6lc00231e"
}

Chen, Q., Utech, S., Chen, D., Prodanović, R., Lin, J.,& Weitz, D. A.. (2016). Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet. in Lab on A Chip
Royal Soc Chemistry, Cambridge., 16(8), 1346-1349.
https://doi.org/10.1039/c6lc00231e

Chen Q, Utech S, Chen D, Prodanović R, Lin J, Weitz DA. Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet. in Lab on A Chip. 2016;16(8):1346-1349.
doi:10.1039/c6lc00231e .

Chen, Qiushui, Utech, Stefanie, Chen, Dong, Prodanović, Radivoje, Lin, Jin-Ming, Weitz, David A., "Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet" in Lab on A Chip, 16, no. 8 (2016):1346-1349,
https://doi.org/10.1039/c6lc00231e . .