Production of bacterial nanocellulose (BNC) and its application as a solid support in transition metal catalysed cross-coupling reactions
Božinović, Nina S.
Pavlović, Vladimir D.
Manojlović, Dragan D.
Babu, Ramesh P.
Article (Accepted Version)
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Bacterial nanocellulose (BNC) emerged as an attractive advanced biomaterial that provides desirable properties such as high strength, lightweight, tailorable surface chemistry, hydrophilicity, and biodegradability. BNC was successfully obtained from a wide range of carbon sources including sugars derived from grass biomass using Komagataeibacter medellinensis ID13488 strain with yields up to 6 g L −1 in static fermentation. Produced BNC was utilized in straightforward catalyst preparation as a solid support for two different transition metals, palladium and copper with metal loading of 20 and 3 wt%, respectively. Sustainable catalysts were applied in the synthesis of valuable fine chemicals, such as biphenyl-4-amine and 4′-fluorobiphenyl-4-amine, used in drug discovery, perfumes and dye industries with excellent product yields of up to 99%. Pd/BNC catalyst was reused 4 times and applied in two consecutive reactions, Suzuki-Miyaura cross-coupling reaction followed by hydrogenation of ni...tro to amino group while Cu/BNC catalyst was examined in Chan-Lam coupling reaction. Overall, the environmentally benign process of obtaining nanocellulose from biomass, followed by its utilisation as a solid support in metal-catalysed reactions and its recovery has been described. These findings reveal that BNC is a good support material, and it can be used as a support for different catalytic systems.
Keywords:Bacterial nanocellulose / Cross-coupling reactions, catalysis / Komagataeibacter medellinensis
Source:International Journal of Biological Macromolecules, 2019, 129, 351-360
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- This is the peer-reviewed version of the following article: Jeremic, S.; Djokic, L.; Ajdačić, V.; Božinović, N.; Pavlovic, V.; Manojlović, D. D.; Babu, R.; Senthamaraikannan, R.; Rojas, O.; Opsenica, I.; et al. Production of Bacterial Nanocellulose (BNC) and Its Application as a Solid Support in Transition Metal Catalysed Cross-Coupling Reactions. Int. J. Biol. Macromol. 2019, 129, 351–360. https://doi.org/10.1016/j.ijbiomac.2019.01.154