dc.creator | Gandra, Upendar Reddy | |
dc.creator | Sinopoli, Alessandro | |
dc.creator | Moncho, Salvador | |
dc.creator | Nanda Kumar, Manjula | |
dc.creator | Ninković, Dragan | |
dc.creator | Zarić, Snežana D. | |
dc.creator | Sohail, Muhammad | |
dc.creator | Al-Meer, Saeed | |
dc.creator | Brothers, Edward N. | |
dc.creator | Mazloum, Nayef A. | |
dc.creator | Al-Hashimi, Mohammed | |
dc.creator | Bazzi, Hassan S. | |
dc.date.accessioned | 2019-11-07T16:49:13Z | |
dc.date.available | 2019-11-07T16:49:13Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1944-8244 | |
dc.identifier.uri | https://cherry.chem.bg.ac.rs/handle/123456789/3636 | |
dc.description.abstract | Carbon monoxide (CO) is an important biological gasotransmitter in living cells. Precise spatial and temporal control over release of CO is a major requirement for clinical application. To date, the most reported carbon monoxide releasing materials use expensive fabrication methods and require harmful and poorly designed tissue-penetrating UV irradiation to initiate the CO release precisely at infected sites. Herein, we report the first example of utilizing a green light-responsive CO-releasing polymer P synthesized via ring-opening metathesis polymerization. Both monomer M and polymer P were very stable under dark conditions and CO release was effectively triggered using minimal power and low energy wavelength irradiation (550 nm, ≤28 mW). Time-dependent density functional theory (TD-DFT) calculations were carried out to simulate the electronic transition and insight into the nature of the excitations for both L and M. TD-DFT calculations indicate that the absorption peak of M is mainly due to the excitation of the seventh singlet excited state, S7. Furthermore, stretchable materials using polytetrafluoroethylene (PTFE) strips based on P were fabricated to afford P-PTFE, which can be used as a simple, inexpensive, and portable CO storage bandage. Insignificant cytotoxicity as well as cell permeability was found for M and P against human embryonic kidney cells. | |
dc.publisher | American Chemical Society | |
dc.rights | restrictedAccess | |
dc.source | ACS Applied Materials and Interfaces | |
dc.subject | carbon monoxide (CO) | |
dc.subject | CO-releasing material (CORMat) | |
dc.subject | light-responsive | |
dc.subject | polymer conjugates | |
dc.subject | portable CO storage and CO release bandage | |
dc.title | Green Light-Responsive CO-Releasing Polymeric Materials Derived from Ring-Opening Metathesis Polymerization | |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Синополи, Aлессандро; Зарић, Снежана; Баззи, Хассан С.; Нанда Кумар, Мањула; Нинковић, Драган; Сохаил, Мухаммад; Aл-Меер, Саеед; Бротхерс, Едwард Н.; Мазлоум, Наyеф A.; Aл-Хасхими, Мохаммед; Монцхо, Салвадор; Гандра, Упендар Реддy; | |
dc.citation.volume | 11 | |
dc.citation.issue | 37 | |
dc.citation.spage | 34376 | |
dc.citation.epage | 34384 | |
dc.identifier.wos | 000487179900091 | |
dc.identifier.doi | 10.1021/acsami.9b12628 | |
dc.citation.rank | aM21~ | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-85072508757 | |