Repozitorijum Hemijskog fakulteta - Cherry
Univerzitet u Beogradu - Hemijski fakultet
    • English
    • Српски
    • Српски (Serbia)
  • Srpski (latinica) 
    • Engleski
    • Srpski (ćirilica)
    • Srpski (latinica)
  • Prijava
Pregled zapisa 
  •   Cherry
  • Hemijski fakultet
  • Publikacije
  • Pregled zapisa
  •   Cherry
  • Hemijski fakultet
  • Publikacije
  • Pregled zapisa
JavaScript is disabled for your browser. Some features of this site may not work without it.

Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid

Thumbnail
2020
Bioactivity_biocompatibility_and_pub_2019.pdf (655.7Kb)
Autori
Katanić-Stanković, Jelena
Srećković, Nikola
Mišić, Danijela
Gašić, Uroš M.
Imbimbo, Paola
Monti, Daria M.
Mihailović, Vladimir
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentu
Apstrakt
The plants from genus Salvia, as one of the largest genus in Lamiaceae family, are frequently in use for various purposes, as foods, in cosmetic industry, or in traditional and official medicine. Salvia verticillata L. (liliac sage) is one of sidelined sage species with potential bioactivity, reported in traditional medicine. The aim of this study was to acquire a phytochemical profile of the methanol extract obtained from S. verticillata aerial parts and to evaluate its antioxidant, antimicrobial, and biocompatibility potential. Characteristic compounds of the genus Salvia, such as rosmarinic and caffeic acids, along with their derivatives (e.g. salvianolic and yunnaneic acids isomers) and flavonoids, have been identified by ultrahigh-performance Orbitrap metabolomic fingerprinting as the main phenolic metabolites in S. verticillata. The extract displayed moderate antimicrobial properties and significant antioxidant potential, with the half maximal inhibitory concentration values (IC5...0) ranging from 33 to 73 μg/mL. Importantly, full biocompatibility of the extract with eukaryotic cell lines was observed up to 72 h. The obtained results revealed the presence of polyphenolic bioactive compounds in S. verticillata extract with promising antioxidant potential and significant biocompatibility. In this regard, S. verticillata can find new perspectives of application as a food ingredient, in cosmetic and pharmaceutical industries, as it represents a valuable source of compounds with prominent health properties, with a special focus on rosmarinic acid.

Ključne reči:
Antimicrobial / Antioxidant / Biocompatibility / Lilac sage / Phytochemical analysis / Salvia verticillata L.
Izvor:
Industrial Crops and Products, 2020, 143, 111932-
Izdavač:
  • Elsevier
Finansiranje / projekti:
  • Simultana bioremedijacija i soilifikacija degradiranih prostora, za očuvanje prirodnih resursa biološki aktivnih supstanci i razvoj i proizvodnju biomaterijala i dijetetskih proizvoda (RS-43004)
  • Korelacija strukture i osobina prirodnih i sintetičkih molekula i njihovih kompleksa sa metalima (RS-172017)
  • Fiziološka, hemijska i molekularna analiza diverziteta odabranih retkih i ugroženih biljnih vrsta u cilju ex situ zaštite i produkcije biološki aktivnih jedinjenja (RS-173024)

DOI: 10.1016/j.indcrop.2019.111932

ISSN: 0926-6690

WoS: 000503323200018

Scopus: 2-s2.0-85074711443
[ Google Scholar ]
26
17
URI
https://cherry.chem.bg.ac.rs/handle/123456789/3791
Kolekcije
  • Publikacije
Institucija/grupa
Hemijski fakultet
TY  - JOUR
AU  - Katanić-Stanković, Jelena
AU  - Srećković, Nikola
AU  - Mišić, Danijela
AU  - Gašić, Uroš M.
AU  - Imbimbo, Paola
AU  - Monti, Daria M.
AU  - Mihailović, Vladimir
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3791
AB  - The plants from genus Salvia, as one of the largest genus in Lamiaceae family, are frequently in use for various purposes, as foods, in cosmetic industry, or in traditional and official medicine. Salvia verticillata L. (liliac sage) is one of sidelined sage species with potential bioactivity, reported in traditional medicine. The aim of this study was to acquire a phytochemical profile of the methanol extract obtained from S. verticillata aerial parts and to evaluate its antioxidant, antimicrobial, and biocompatibility potential. Characteristic compounds of the genus Salvia, such as rosmarinic and caffeic acids, along with their derivatives (e.g. salvianolic and yunnaneic acids isomers) and flavonoids, have been identified by ultrahigh-performance Orbitrap metabolomic fingerprinting as the main phenolic metabolites in S. verticillata. The extract displayed moderate antimicrobial properties and significant antioxidant potential, with the half maximal inhibitory concentration values (IC50) ranging from 33 to 73 μg/mL. Importantly, full biocompatibility of the extract with eukaryotic cell lines was observed up to 72 h. The obtained results revealed the presence of polyphenolic bioactive compounds in S. verticillata extract with promising antioxidant potential and significant biocompatibility. In this regard, S. verticillata can find new perspectives of application as a food ingredient, in cosmetic and pharmaceutical industries, as it represents a valuable source of compounds with prominent health properties, with a special focus on rosmarinic acid.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid
VL  - 143
SP  - 111932
DO  - 10.1016/j.indcrop.2019.111932
ER  - 
@article{
author = "Katanić-Stanković, Jelena and Srećković, Nikola and Mišić, Danijela and Gašić, Uroš M. and Imbimbo, Paola and Monti, Daria M. and Mihailović, Vladimir",
year = "2020",
abstract = "The plants from genus Salvia, as one of the largest genus in Lamiaceae family, are frequently in use for various purposes, as foods, in cosmetic industry, or in traditional and official medicine. Salvia verticillata L. (liliac sage) is one of sidelined sage species with potential bioactivity, reported in traditional medicine. The aim of this study was to acquire a phytochemical profile of the methanol extract obtained from S. verticillata aerial parts and to evaluate its antioxidant, antimicrobial, and biocompatibility potential. Characteristic compounds of the genus Salvia, such as rosmarinic and caffeic acids, along with their derivatives (e.g. salvianolic and yunnaneic acids isomers) and flavonoids, have been identified by ultrahigh-performance Orbitrap metabolomic fingerprinting as the main phenolic metabolites in S. verticillata. The extract displayed moderate antimicrobial properties and significant antioxidant potential, with the half maximal inhibitory concentration values (IC50) ranging from 33 to 73 μg/mL. Importantly, full biocompatibility of the extract with eukaryotic cell lines was observed up to 72 h. The obtained results revealed the presence of polyphenolic bioactive compounds in S. verticillata extract with promising antioxidant potential and significant biocompatibility. In this regard, S. verticillata can find new perspectives of application as a food ingredient, in cosmetic and pharmaceutical industries, as it represents a valuable source of compounds with prominent health properties, with a special focus on rosmarinic acid.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid",
volume = "143",
pages = "111932",
doi = "10.1016/j.indcrop.2019.111932"
}
Katanić-Stanković, J., Srećković, N., Mišić, D., Gašić, U. M., Imbimbo, P., Monti, D. M.,& Mihailović, V.. (2020). Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid. in Industrial Crops and Products
Elsevier., 143, 111932.
https://doi.org/10.1016/j.indcrop.2019.111932
Katanić-Stanković J, Srećković N, Mišić D, Gašić UM, Imbimbo P, Monti DM, Mihailović V. Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid. in Industrial Crops and Products. 2020;143:111932.
doi:10.1016/j.indcrop.2019.111932 .
Katanić-Stanković, Jelena, Srećković, Nikola, Mišić, Danijela, Gašić, Uroš M., Imbimbo, Paola, Monti, Daria M., Mihailović, Vladimir, "Bioactivity, biocompatibility and phytochemical assessment of lilac sage, Salvia verticillata L. (Lamiaceae) - A plant rich in rosmarinic acid" in Industrial Crops and Products, 143 (2020):111932,
https://doi.org/10.1016/j.indcrop.2019.111932 . .

DSpace software copyright © 2002-2015  DuraSpace
O repozitorijumu CHERRY (CHEmistry RepositoRY) | Pošaljite zapažanja

re3dataOpenAIRERCUB
 

 

Kompletan repozitorijumInstitucije/grupeAutoriNasloviTemeOva institucijaAutoriNasloviTeme

Statistika

Pregled statistika

DSpace software copyright © 2002-2015  DuraSpace
O repozitorijumu CHERRY (CHEmistry RepositoRY) | Pošaljite zapažanja

re3dataOpenAIRERCUB