Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations
Само за регистроване кориснике
2020
Аутори
Mészáros, János P.Geisler, Heiko
Poljarević, Jelena
Roller, Alexander
Legina, Maria S.
Hejl, Michaela
Jakupec, Michael A.
Keppler, Bernhard K.
Kandioller, Wolfgang
Enyedy, Éva A.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and solution phase by analytical, spectroscopic, electrochemical and single crystal X-ray diffraction techniques. Comparative studies revealed the influence of the respective metal center (Ru, Os, Rh), leaving group (Cl, Br, I) and arene (p-cymene, toluene, pentamethylcyclopentadienyl), as well as the naphthoquinone ligand on the structural properties and solution speciation. Additionally, cytotoxicity was tested in SW480, CH1/PA-1 and A549 human cancer cell lines showing a broad range of IC50 values.
Кључне речи:
Cytotoxicity / Half-sandwich complexes / Natural ligands / Solution stability / X-ray crystal structuresИзвор:
Journal of Organometallic Chemistry, 2020, 907Издавач:
- Elsevier
Финансирање / пројекти:
- GINOP-2.3.2-15- 2016-00038
- FK 124240
- FIKP program TUDFO/47138e1/2019- ITM. J.P. M
- ÚNKP-19-3 National Excellence Program of the Ministry for Innovation and Technology
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3805
DOI: 10.1016/j.jorganchem.2019.121070
ISSN: 0022-328X
WoS: 000506406600004
Scopus: 2-s2.0-85076311922
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Mészáros, János P. AU - Geisler, Heiko AU - Poljarević, Jelena AU - Roller, Alexander AU - Legina, Maria S. AU - Hejl, Michaela AU - Jakupec, Michael A. AU - Keppler, Bernhard K. AU - Kandioller, Wolfgang AU - Enyedy, Éva A. PY - 2020 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3804 AB - Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and solution phase by analytical, spectroscopic, electrochemical and single crystal X-ray diffraction techniques. Comparative studies revealed the influence of the respective metal center (Ru, Os, Rh), leaving group (Cl, Br, I) and arene (p-cymene, toluene, pentamethylcyclopentadienyl), as well as the naphthoquinone ligand on the structural properties and solution speciation. Additionally, cytotoxicity was tested in SW480, CH1/PA-1 and A549 human cancer cell lines showing a broad range of IC50 values. PB - Elsevier T2 - Journal of Organometallic Chemistry T1 - Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations VL - 907 DO - 10.1016/j.jorganchem.2019.121070 ER -
@article{ author = "Mészáros, János P. and Geisler, Heiko and Poljarević, Jelena and Roller, Alexander and Legina, Maria S. and Hejl, Michaela and Jakupec, Michael A. and Keppler, Bernhard K. and Kandioller, Wolfgang and Enyedy, Éva A.", year = "2020", abstract = "Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and solution phase by analytical, spectroscopic, electrochemical and single crystal X-ray diffraction techniques. Comparative studies revealed the influence of the respective metal center (Ru, Os, Rh), leaving group (Cl, Br, I) and arene (p-cymene, toluene, pentamethylcyclopentadienyl), as well as the naphthoquinone ligand on the structural properties and solution speciation. Additionally, cytotoxicity was tested in SW480, CH1/PA-1 and A549 human cancer cell lines showing a broad range of IC50 values.", publisher = "Elsevier", journal = "Journal of Organometallic Chemistry", title = "Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations", volume = "907", doi = "10.1016/j.jorganchem.2019.121070" }
Mészáros, J. P., Geisler, H., Poljarević, J., Roller, A., Legina, M. S., Hejl, M., Jakupec, M. A., Keppler, B. K., Kandioller, W.,& Enyedy, É. A.. (2020). Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations. in Journal of Organometallic Chemistry Elsevier., 907. https://doi.org/10.1016/j.jorganchem.2019.121070
Mészáros JP, Geisler H, Poljarević J, Roller A, Legina MS, Hejl M, Jakupec MA, Keppler BK, Kandioller W, Enyedy ÉA. Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations. in Journal of Organometallic Chemistry. 2020;907. doi:10.1016/j.jorganchem.2019.121070 .
Mészáros, János P., Geisler, Heiko, Poljarević, Jelena, Roller, Alexander, Legina, Maria S., Hejl, Michaela, Jakupec, Michael A., Keppler, Bernhard K., Kandioller, Wolfgang, Enyedy, Éva A., "Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations" in Journal of Organometallic Chemistry, 907 (2020), https://doi.org/10.1016/j.jorganchem.2019.121070 . .