Cyclization Reactions of Oxyallyl Cation. A Method for Cyclopentane Ring Formation
Abstract
Unsaturated oxyallyl cations with a suitably positioned alkene bond undergo 5-exo-cyclization with the formation of vinylcyclopentane derivatives. Alkyne analogues provide allenes. The reaction proceeds with a moderate to excellent level of stereoselectivity and allows for asymmetric induction in the reaction with chiral substrate.
Source:
Organic Letters, 2019, 21, 23, 9618-9621Publisher:
- ACS
Projects:
- The development of new synthetic methods and their application in the synthesis of natural products and biologically active molecules (RS-172027)
- Serbian Academy of Sciences and Arts (Project No. F193)
- Reinforcement of the Faculty of Chemistry, University of Belgrade, towards becoming a Center of Excellence in the region of WB for Molecular Biotechnology and Food research (EU-256716)
Note:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3841
DOI: 10.1021/acs.orglett.9b03791
ISSN: 1523-7060