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dc.creatorTrifunović, Snežana S.
dc.creatorVajs, Vlatka
dc.creatorMacura, S
dc.creatorJuranic, N
dc.creatorDjarmati, Z
dc.creatorJankov, Ratko M.
dc.creatorMilosavljevic, S
dc.date.accessioned2018-11-22T00:02:23Z
dc.date.available2018-11-22T00:02:23Z
dc.date.issued1998
dc.identifier.issn0031-9422
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/400
dc.description.abstractThe isolation of two oxidation products of hyperforin from the aerial parts of Hypericum perforatum and their structure determination by means of 2D NMR methods is reported. The products had the same 1-(2-methyl-1-oxopropyl)-2,12-dioxo-3,10 beta-bis(3-methyl-2-butenyl)-11 beta-methyl-11 alpha-(4-methyl-3-pentenyl)-5-oxatricyclo[6.3.1.0(4.8)]-3-dodecene skeleton. In addition, one of them, with the same number of carbons as hyperforin (C35H52O5), contained a 1-methyl-1-hydroxyethyl group in the 6 beta-position, whereas the other compound (a hemiacetal, C32H46O5), presumably a degradation product of hyperforin, exhibited a 6-hydroxy function. The latter was an inseparable mixture of 6 alpha- and 6 beta-hydroxy epimers undergoing (according to phase sensitive NOESY) mutual :interconversion. (C) 1998 Elsevier Science Ltd. All rights reserved.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.rightsrestrictedAccess
dc.sourcePhytochemistry
dc.subjectHypericum perforatumen
dc.subjectHypericaceaeen
dc.subjectsupercritical CO2 fractionationen
dc.subjectoxidized hyperforinsen
dc.titleOxidation products of hyperforin from Hypericum perforatumen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДјармати, З; Вајс, В; Мацура, С; Јураниц, Н; Милосављевиц, С; Јанков, Р; Трифуновић, Снежана;
dc.citation.volume49
dc.citation.issue5
dc.citation.spage1305
dc.citation.epage1310
dc.identifier.wos000077125100024
dc.identifier.doi10.1016/S0031-9422(97)00903-5
dc.citation.other49(5): 1305-1310
dc.citation.rankM22
dc.identifier.pmid9842729
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-0032487784
dc.identifier.rcubKon_1373


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