Semisynthesis of Taxol (R): an improved procedure far the isolation of 10-deacetylbaccatin III

dc.creator	Saičić, Radomir
dc.creator	Matović, Radomir
dc.creator	Čeković, Živorad
dc.date.accessioned	2018-11-22T00:02:46Z
dc.date.available	2018-11-22T00:02:46Z
dc.date.issued	1999
dc.identifier.issn	0352-5139
dc.identifier.uri	https://cherry.chem.bg.ac.rs/handle/123456789/419
dc.description.abstract	From the needles of domestic yew, (Taxus baccata), 10-deacetylbaccatin III (10-DAB) call be isolated in quantities of up to 297 mg per kg of fresh needles. Additional quantities of 10-DAB call be obtained from the extract by NaBH4 mediated reductive hydrolysis of baccatin esters. A four-step procedure converts 10-DAB into taxol in 58% overall yield.	en
dc.publisher	Serbian Chemical Soc, Belgrade
dc.rights	restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.source	Journal of the Serbian Chemical Society
dc.subject	anti-tumor agents	en
dc.subject	taxol	en
dc.subject	natural products	en
dc.subject	semisynthesis	en
dc.title	Semisynthesis of Taxol (R): an improved procedure far the isolation of 10-deacetylbaccatin III	en
dc.type	article
dc.rights.license	BY-NC-ND
dcterms.abstract	Матовиц, Р; Саичић, Радомир; Цековиц, З;
dc.citation.volume	64
dc.citation.issue	9
dc.citation.spage	497
dc.citation.epage	503
dc.identifier.wos	000082557600001
dc.citation.other	64(9): 497-503
dc.type.version	publishedVersion	en
dc.identifier.scopus	2-s2.0-0038929346
dc.identifier.rcub	https://hdl.handle.net/21.15107/rcub_cherry_419

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