Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents
Authorized Users Only
2019
Authors
Senerovic, LidijaOpsenica, Dejan M.

Moric, Ivana
Aleksic, Ivana
Spasić, Marta
Vasiljević, Branka

Book part (Published version)

Springer Nature Switzerland AG 2019
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Infective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone de...rivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature.
Keywords:
Antibiotics / Antifungals / Anti-parasitics / Antivirals / Anti-virulence activity / Quinoline/quinolone derivativesSource:
Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health, 2019Publisher:
- Springer Nature
Funding / projects:
- The synthesis of aminoquinoline-based antimalarials and botulinum neurotoxin A inhibitors (RS-172008)
- Microbial diversity study and characterization of beneficial environmental microorganisms (RS-173048)
DOI: 10.1007/5584_2019_428
ISSN: 2365-2675
PubMed: 31515709
Scopus: 2-s2.0-85089126743
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Hemijski fakultet / Faculty of ChemistryTY - CHAP AU - Senerovic, Lidija AU - Opsenica, Dejan M. AU - Moric, Ivana AU - Aleksic, Ivana AU - Spasić, Marta AU - Vasiljević, Branka PY - 2019 UR - https://cherry.chem.bg.ac.rs/handle/123456789/4274 AB - Infective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone derivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature. PB - Springer Nature T2 - Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health T1 - Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents DO - 10.1007/5584_2019_428 ER -
@inbook{ author = "Senerovic, Lidija and Opsenica, Dejan M. and Moric, Ivana and Aleksic, Ivana and Spasić, Marta and Vasiljević, Branka", year = "2019", abstract = "Infective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone derivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature.", publisher = "Springer Nature", journal = "Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health", booktitle = "Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents", doi = "10.1007/5584_2019_428" }
Senerovic, L., Opsenica, D. M., Moric, I., Aleksic, I., Spasić, M.,& Vasiljević, B.. (2019). Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents. in Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health Springer Nature.. https://doi.org/10.1007/5584_2019_428
Senerovic L, Opsenica DM, Moric I, Aleksic I, Spasić M, Vasiljević B. Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents. in Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health. 2019;. doi:10.1007/5584_2019_428 .
Senerovic, Lidija, Opsenica, Dejan M., Moric, Ivana, Aleksic, Ivana, Spasić, Marta, Vasiljević, Branka, "Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents" in Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health (2019), https://doi.org/10.1007/5584_2019_428 . .