Infective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone de...rivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature.
TY - CHAP
AU - Senerovic, Lidija
AU - Opsenica, Dejan
AU - Moric, Ivana
AU - Aleksic, Ivana
AU - Spasić, Marta
AU - Vasiljevic, Branka
PY - 2019
UR - http://cherry.chem.bg.ac.rs/handle/123456789/4274
AB - Infective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone derivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature.
PB - Springer Nature
T2 - Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health
T1 - Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents
DO - 10.1007/5584_2019_428
ER -
@article{
author = "Senerovic, Lidija and Opsenica, Dejan and Moric, Ivana and Aleksic, Ivana and Spasić, Marta and Vasiljevic, Branka",
year = "2019",
url = "http://cherry.chem.bg.ac.rs/handle/123456789/4274",
abstract = "Infective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone derivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature.",
publisher = "Springer Nature",
journal = "Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health",
title = "Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents",
doi = "10.1007/5584_2019_428"
}
Senerovic L, Opsenica D, Moric I, Aleksic I, Spasić M, Vasiljevic B. Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents. Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Health. 2019;
Senerovic, L., Opsenica, D., Moric, I., Aleksic, I., Spasić, M.,& Vasiljevic, B. (2019). Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents.
Advances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public HealthSpringer Nature..
https://doi.org/10.1007/5584_2019_428
Senerovic Lidija, Opsenica Dejan, Moric Ivana, Aleksic Ivana, Spasić Marta, Vasiljevic Branka, "Quinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agents" (2019),
https://doi.org/10.1007/5584_2019_428 .
, 