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dc.creatorSenerovic, Lidija
dc.creatorOpsenica, Dejan
dc.creatorMoric, Ivana
dc.creatorAleksic, Ivana
dc.creatorSpasić, Marta
dc.creatorVasiljevic, Branka
dc.date.accessioned2020-12-12T10:31:37Z
dc.date.available2020-12-12T10:31:37Z
dc.date.issued2019
dc.identifier.issn2365-2675
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/4274
dc.description.abstractInfective diseases have become health threat ofa global proportion due to appearance andspread of microorganisms resistant to majorityof therapeutics currently used for their treatment.Therefore, there is a constant need fordevelopment of new antimicrobial agents, aswell as novel therapeutic strategies.Quinolines and quinolones, isolated fromplants, animals, and microorganisms, havedemonstrated numerous biological activitiessuch as antimicrobial, insecticidal, antiinflammatory,antiplatelet, and antitumor. Formore than two centuries quinoline/quinolonemoiety has been used as a scaffold for drugdevelopment and even today it represents aninexhaustible inspiration for design and developmentof novel semi-synthetic or syntheticagents exhibiting broad spectrum ofbioactivities. The structural diversity ofsynthetized compounds provides high andselective activity attained through differentmechanisms of action, as well as low toxicityon human cells. This review describes quinolineand quinolone derivatives withantibacterial, antifungal, anti-virulent,antiviral, and anti-parasitic activities with thefocus on the last 10 years literature.sr
dc.language.isoensr
dc.publisherSpringer Naturesr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172008/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173048/RS//sr
dc.rightsrestrictedAccesssr
dc.sourceAdvances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Healthsr
dc.subjectAntibioticssr
dc.subjectAntifungalssr
dc.subjectAnti-parasiticssr
dc.subjectAntiviralssr
dc.subjectAnti-virulence activitysr
dc.subjectQuinoline/quinolone derivativessr
dc.titleQuinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agentssr
dc.typebookPartsr
dc.rights.licenseARRsr
dcterms.abstractВасиљевиц, Бранка; Сенеровиц, Лидија; Aлексиц, Ивана; Спасић, Марта; Мориц, Ивана; Опсеница, Дејан;
dc.rights.holderSpringer Nature Switzerland AG 2019sr
dc.identifier.doi10.1007/5584_2019_428
dc.identifier.pmid31515709
dc.type.versionpublishedVersionsr
dc.identifier.scopus2-s2.0-85089126743


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