Faculty of Chemistry Repository - Cherry
University of Belgrade - Faculty of Chemistry
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrilic)
    • Serbian (Latin)
  • Login
View Item 
  •   Faculty of Chemistry Repository - Cherry
  • Hemijski fakultet
  • Publikacije
  • View Item
  •   Faculty of Chemistry Repository - Cherry
  • Hemijski fakultet
  • Publikacije
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Cobalt(II), Zinc(II), Iron(III), and Copper(II) Complexes Bearing Positively Charged Quaternary Ammonium Functionalities: Synthesis, Characterization, Electrochemical Behavior, and SOD Activity

Thumbnail
2020
Cobalt(II)_Zinc(II)_Iron(III)_pub_2020.pdf (2.203Mb)
Authors
Stojičkov, Marko
Sturm, Sabrina
Čobeljić, Božidar
Pevec, Andrej
Jevtović, Mima
Scheitler, Andreas
Radanović, Dušanka
Senft, Laura
Turel, Iztok
Anđelković, Katarina K.
Miehlich, Matthias
Meyer, Karsten
Ivanović‐Burmazović, Ivana
Article (Published version)
Metadata
Show full item record
Abstract
We have synthesized and characterized Co(II) (1), Zn(II) (2), Fe(III) (3) and Cu(II) (4) complexes of 2,2'‐[2,6‐pyridinediylbis(ethylidyne‐1‐hydrazinyl‐2‐ylidene)]bis[N,N,N‐trimethyl‐2‐oxoethanaminium] dichloride (H2LCl2) by NMR, IR, and X‐Band EPR spectroscopy, respectively, as well as by single‐crystal X‐ray structural analysis. H2LCl2 belongs to the class of diacetylpyridine bis(hydrazone) ligands and bears two positively charged quaternary ammonium functionalities. The complexes 1–3 possess a pentagonal‐bipyramidal geometry, whereas 4 has square‐pyramidal geometry. Redox reactivity and SOD activity of the complexes was studied by means of electrochemical measurements in aqueous‐buffer and DMF or DMSO solutions, respectively, as well as by stopped‐flow measurements. Complexes 1–3 do not have SOD activity, whereas 4 exhibits a high catalytic rate constant for the superoxide dismutation, kcat = 1.73 × 107 m–1 s–1 (in MOPS buffer solution of pH = 7.4). The results were discussed in ter...ms of complex redox potentials, electrostatic interactions and their spatial distribution, kinetic lability of metal centers, and stability of peroxo intermediates, respectively.

Keywords:
Cobalt / Copper / Electrochemistry / Iron / SOD activity / Structure elucidation
Source:
European Journal of Inorganic Chemistry, 2020, 3347-3358
Publisher:
  • Wiley-VCH Verlag
Projects:
  • Interactions of natural products, their derivatives and coordination compounds with proteins and nucleic acids (RS-172055)
  • Slovenian Research Agency (ARRS) through program P‐0175
  • ERASMUS + program
  • DFG (IV 80/13‐1 project)
  • Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) (RS-200026)

DOI: 10.1002/ejic.202000415

ISSN: 1099-0682

WoS: 000564577200001

Scopus: 2-s2.0-85090058906
[ Google Scholar ]
URI
http://cherry.chem.bg.ac.rs/handle/123456789/4285
Collections
  • Publikacije
Institution
Hemijski fakultet
TY  - JOUR
AU  - Stojičkov, Marko
AU  - Sturm, Sabrina
AU  - Čobeljić, Božidar
AU  - Pevec, Andrej
AU  - Jevtović, Mima
AU  - Scheitler, Andreas
AU  - Radanović, Dušanka
AU  - Senft, Laura
AU  - Turel, Iztok
AU  - Anđelković, Katarina K.
AU  - Miehlich, Matthias
AU  - Meyer, Karsten
AU  - Ivanović‐Burmazović, Ivana
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4285
AB  - We have synthesized and characterized Co(II) (1), Zn(II) (2), Fe(III) (3) and Cu(II) (4) complexes of 2,2'‐[2,6‐pyridinediylbis(ethylidyne‐1‐hydrazinyl‐2‐ylidene)]bis[N,N,N‐trimethyl‐2‐oxoethanaminium] dichloride (H2LCl2) by NMR, IR, and X‐Band EPR spectroscopy, respectively, as well as by single‐crystal X‐ray structural analysis. H2LCl2 belongs to the class of diacetylpyridine bis(hydrazone) ligands and bears two positively charged quaternary ammonium functionalities. The complexes 1–3 possess a pentagonal‐bipyramidal geometry, whereas 4 has square‐pyramidal geometry. Redox reactivity and SOD activity of the complexes was studied by means of electrochemical measurements in aqueous‐buffer and DMF or DMSO solutions, respectively, as well as by stopped‐flow measurements. Complexes 1–3 do not have SOD activity, whereas 4 exhibits a high catalytic rate constant for the superoxide dismutation, kcat = 1.73 × 107 m–1 s–1 (in MOPS buffer solution of pH = 7.4). The results were discussed in terms of complex redox potentials, electrostatic interactions and their spatial distribution, kinetic lability of metal centers, and stability of peroxo intermediates, respectively.
PB  - Wiley-VCH Verlag
T2  - European Journal of Inorganic Chemistry
T1  - Cobalt(II), Zinc(II), Iron(III), and Copper(II) Complexes Bearing Positively Charged Quaternary Ammonium Functionalities: Synthesis, Characterization, Electrochemical Behavior, and SOD Activity
SP  - 3347
EP  - 3358
DO  - 10.1002/ejic.202000415
ER  - 
@article{
author = "Stojičkov, Marko and Sturm, Sabrina and Čobeljić, Božidar and Pevec, Andrej and Jevtović, Mima and Scheitler, Andreas and Radanović, Dušanka and Senft, Laura and Turel, Iztok and Anđelković, Katarina K. and Miehlich, Matthias and Meyer, Karsten and Ivanović‐Burmazović, Ivana",
year = "2020",
url = "http://cherry.chem.bg.ac.rs/handle/123456789/4285",
abstract = "We have synthesized and characterized Co(II) (1), Zn(II) (2), Fe(III) (3) and Cu(II) (4) complexes of 2,2'‐[2,6‐pyridinediylbis(ethylidyne‐1‐hydrazinyl‐2‐ylidene)]bis[N,N,N‐trimethyl‐2‐oxoethanaminium] dichloride (H2LCl2) by NMR, IR, and X‐Band EPR spectroscopy, respectively, as well as by single‐crystal X‐ray structural analysis. H2LCl2 belongs to the class of diacetylpyridine bis(hydrazone) ligands and bears two positively charged quaternary ammonium functionalities. The complexes 1–3 possess a pentagonal‐bipyramidal geometry, whereas 4 has square‐pyramidal geometry. Redox reactivity and SOD activity of the complexes was studied by means of electrochemical measurements in aqueous‐buffer and DMF or DMSO solutions, respectively, as well as by stopped‐flow measurements. Complexes 1–3 do not have SOD activity, whereas 4 exhibits a high catalytic rate constant for the superoxide dismutation, kcat = 1.73 × 107 m–1 s–1 (in MOPS buffer solution of pH = 7.4). The results were discussed in terms of complex redox potentials, electrostatic interactions and their spatial distribution, kinetic lability of metal centers, and stability of peroxo intermediates, respectively.",
publisher = "Wiley-VCH Verlag",
journal = "European Journal of Inorganic Chemistry",
title = "Cobalt(II), Zinc(II), Iron(III), and Copper(II) Complexes Bearing Positively Charged Quaternary Ammonium Functionalities: Synthesis, Characterization, Electrochemical Behavior, and SOD Activity",
pages = "3347-3358",
doi = "10.1002/ejic.202000415"
}
Stojičkov M, Sturm S, Čobeljić B, Pevec A, Jevtović M, Scheitler A, Radanović D, Senft L, Turel I, Anđelković KK, Miehlich M, Meyer K, Ivanović‐Burmazović I. Cobalt(II), Zinc(II), Iron(III), and Copper(II) Complexes Bearing Positively Charged Quaternary Ammonium Functionalities: Synthesis, Characterization, Electrochemical Behavior, and SOD Activity. European Journal of Inorganic Chemistry. 2020;:3347-3358
Stojičkov, M., Sturm, S., Čobeljić, B., Pevec, A., Jevtović, M., Scheitler, A., Radanović, D., Senft, L., Turel, I., Anđelković, K. K., Miehlich, M., Meyer, K.,& Ivanović‐Burmazović, I. (2020). Cobalt(II), Zinc(II), Iron(III), and Copper(II) Complexes Bearing Positively Charged Quaternary Ammonium Functionalities: Synthesis, Characterization, Electrochemical Behavior, and SOD Activity.
European Journal of Inorganic ChemistryWiley-VCH Verlag., 3347-3358.
https://doi.org/10.1002/ejic.202000415
Stojičkov Marko, Sturm Sabrina, Čobeljić Božidar, Pevec Andrej, Jevtović Mima, Scheitler Andreas, Radanović Dušanka, Senft Laura, Turel Iztok, Anđelković Katarina K., Miehlich Matthias, Meyer Karsten, Ivanović‐Burmazović Ivana, "Cobalt(II), Zinc(II), Iron(III), and Copper(II) Complexes Bearing Positively Charged Quaternary Ammonium Functionalities: Synthesis, Characterization, Electrochemical Behavior, and SOD Activity" (2020):3347-3358,
https://doi.org/10.1002/ejic.202000415 .

DSpace software copyright © 2002-2015  DuraSpace
About CHERRY - CHEmistry RepositoRY | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceInstitutionsAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About CHERRY - CHEmistry RepositoRY | Send Feedback

OpenAIRERCUB