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dc.creatorNikolić, Andrea M.
dc.creatorŽivković, Filip
dc.creatorSelaković, Života
dc.creatorWipf, Peter
dc.creatorOpsenica, Igor
dc.date.accessioned2020-12-14T08:33:36Z
dc.date.available2020-12-14T08:33:36Z
dc.date.issued2020
dc.identifier.issn1099-0690
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/4294
dc.description.abstractAn efficient one-pot, two step method for fusing two biologically active motifs, CF3-substituted pyrazoles and isochromenes, was developed. Selective O-benzylation of CF3-substituted pyrazolones and subsequent Pd-catalyzed direct C–H arylation generate a fused tricycle. For the synthesized compounds through-space 13C–19F spin–spin coupling was revealed. In addition, the synthesis of three thioisochromene analogues, and one isocoumarin derivative, was accomplished.
dc.languageen
dc.publisherWiley
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS//
dc.relationSerbianAcademy of Sciences and Arts under strategic projects pro-gramme - grant agreement No. 01-2019-F65.
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/256716/EU//
dc.rightsrestrictedAccess
dc.sourceEuropean Journal of Organic Chemistry
dc.source2-s2.0-85089311831
dc.subjectC–F correlation
dc.subjectHeterocycles
dc.subjectIsochromenes
dc.subjectPalladium
dc.subjectPyrazoles
dc.titleOne-Pot Two-Step Synthesis of Isochromene-Fused CF3-Substituted Pyrazoles
dc.typearticleen
dc.rights.licenseARR
dcterms.abstractНиколић, Aндреа М.; Живковић, Филип; Селаковић, Живота; Wипф, Петер; Опсеница, Игор;
dc.citation.volume2020
dc.citation.issue34
dc.citation.spage5616
dc.citation.epage5619
dc.identifier.wos000558493900001
dc.identifier.doihttps://doi.org/10.1002/ejoc.202000942
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85089311831


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