Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts
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2021
Authors
Filip, SnežanaĐurović, Saša

Blagojević, Stevan

Tomić, Ana

Ranitović, Aleksandra
Gašić, Uroš M.

Tešić, Živoslav Lj.

Zeković, Zoran P.
Article (Published version)

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The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra‐high‐performance liquid chromatography, with a diode array detector coupled with triple‐quadrupole mass spectrometer and gas chromatography–mass spectrometry techniques. Thirty‐one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5‐O‐caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram‐positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATC...C 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.
Keywords:
antimicrobial activity / chemical profile / leaf extraction / Maclura pomifera (Osage orange) / MoraceaeSource:
Archiv der Pharmazie, 2021, 354, e2000195-Publisher:
- Wiley
Funding / projects:
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-200007)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200051 (Institute of General and Physical Chemistry, Belgrade) (RS-200051)
DOI: 10.1002/ardp.202000195
ISSN: 0365-6233
WoS: 000585342500001
Scopus: 2-s2.0-85092402429
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Filip, Snežana AU - Đurović, Saša AU - Blagojević, Stevan AU - Tomić, Ana AU - Ranitović, Aleksandra AU - Gašić, Uroš M. AU - Tešić, Živoslav Lj. AU - Zeković, Zoran P. PY - 2021 UR - https://cherry.chem.bg.ac.rs/handle/123456789/4338 AB - The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra‐high‐performance liquid chromatography, with a diode array detector coupled with triple‐quadrupole mass spectrometer and gas chromatography–mass spectrometry techniques. Thirty‐one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5‐O‐caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram‐positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties. PB - Wiley T2 - Archiv der Pharmazie T1 - Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts VL - 354 SP - e2000195 DO - 10.1002/ardp.202000195 ER -
@article{ author = "Filip, Snežana and Đurović, Saša and Blagojević, Stevan and Tomić, Ana and Ranitović, Aleksandra and Gašić, Uroš M. and Tešić, Živoslav Lj. and Zeković, Zoran P.", year = "2021", abstract = "The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra‐high‐performance liquid chromatography, with a diode array detector coupled with triple‐quadrupole mass spectrometer and gas chromatography–mass spectrometry techniques. Thirty‐one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5‐O‐caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram‐positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.", publisher = "Wiley", journal = "Archiv der Pharmazie", title = "Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts", volume = "354", pages = "e2000195", doi = "10.1002/ardp.202000195" }
Filip, S., Đurović, S., Blagojević, S., Tomić, A., Ranitović, A., Gašić, U. M., Tešić, Ž. Lj.,& Zeković, Z. P.. (2021). Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts. in Archiv der Pharmazie Wiley., 354, e2000195. https://doi.org/10.1002/ardp.202000195
Filip S, Đurović S, Blagojević S, Tomić A, Ranitović A, Gašić UM, Tešić ŽL, Zeković ZP. Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts. in Archiv der Pharmazie. 2021;354:e2000195. doi:10.1002/ardp.202000195 .
Filip, Snežana, Đurović, Saša, Blagojević, Stevan, Tomić, Ana, Ranitović, Aleksandra, Gašić, Uroš M., Tešić, Živoslav Lj., Zeković, Zoran P., "Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts" in Archiv der Pharmazie, 354 (2021):e2000195, https://doi.org/10.1002/ardp.202000195 . .