Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone
Abstract
Based on biological properties of epoxyquinols from natural sources, bromo and epoxyquinols derived from estrone were synthesized and screened against Fem-X. HeLa and K-562 cell lines. Evidence was found that the bromine atom and the epoxy moiety significantly increase the antiproliferative activity within the series. (C) 2001 Elsevier Science Ltd. All rights reserved.
Source:
Bioorganic and Medicinal Chemistry Letters, 2001, 11, 16, 2197-2200Publisher:
- Pergamon-Elsevier Science Ltd, Oxford
DOI: 10.1016/S0960-894X(01)00402-4
ISSN: 0960-894X
PubMed: 11514169
WoS: 000170325000032
Scopus: 2-s2.0-0035921015
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Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Milić, Dragana AU - Kop, Tatjana AU - Juranić, Z. AU - Gasic, MJ AU - Šolaja, Bogdan A. PY - 2001 UR - https://cherry.chem.bg.ac.rs/handle/123456789/468 AB - Based on biological properties of epoxyquinols from natural sources, bromo and epoxyquinols derived from estrone were synthesized and screened against Fem-X. HeLa and K-562 cell lines. Evidence was found that the bromine atom and the epoxy moiety significantly increase the antiproliferative activity within the series. (C) 2001 Elsevier Science Ltd. All rights reserved. PB - Pergamon-Elsevier Science Ltd, Oxford T2 - Bioorganic and Medicinal Chemistry Letters T1 - Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone VL - 11 IS - 16 SP - 2197 EP - 2200 DO - 10.1016/S0960-894X(01)00402-4 ER -
@article{ author = "Milić, Dragana and Kop, Tatjana and Juranić, Z. and Gasic, MJ and Šolaja, Bogdan A.", year = "2001", abstract = "Based on biological properties of epoxyquinols from natural sources, bromo and epoxyquinols derived from estrone were synthesized and screened against Fem-X. HeLa and K-562 cell lines. Evidence was found that the bromine atom and the epoxy moiety significantly increase the antiproliferative activity within the series. (C) 2001 Elsevier Science Ltd. All rights reserved.", publisher = "Pergamon-Elsevier Science Ltd, Oxford", journal = "Bioorganic and Medicinal Chemistry Letters", title = "Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone", volume = "11", number = "16", pages = "2197-2200", doi = "10.1016/S0960-894X(01)00402-4" }
Milić, D., Kop, T., Juranić, Z., Gasic, M.,& Šolaja, B. A.. (2001). Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone. in Bioorganic and Medicinal Chemistry Letters Pergamon-Elsevier Science Ltd, Oxford., 11(16), 2197-2200. https://doi.org/10.1016/S0960-894X(01)00402-4
Milić D, Kop T, Juranić Z, Gasic M, Šolaja BA. Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone. in Bioorganic and Medicinal Chemistry Letters. 2001;11(16):2197-2200. doi:10.1016/S0960-894X(01)00402-4 .
Milić, Dragana, Kop, Tatjana, Juranić, Z., Gasic, MJ, Šolaja, Bogdan A., "Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone" in Bioorganic and Medicinal Chemistry Letters, 11, no. 16 (2001):2197-2200, https://doi.org/10.1016/S0960-894X(01)00402-4 . .